Search results
- 1.0532352 - FGÚ 2021 RIV US eng J - Journal Article
Plecitá-Hlavatá, Lydie - Engstová, Hana - Holendová, Blanka - Tauber, Jan - Špaček, Tomáš - Petrásková, Lucie - Křen, Vladimír - Špačková, Jitka - Gotvaldová, Klára - Ježek, Jan - Dlasková, Andrea - Smolková, Katarína - Ježek, Petr
Mitochondrial Superoxide Production Decreases on Glucose-Stimulated Insulin Secretion in Pancreatic beta Cells Due to Decreasing Mitochondrial Matrix NADH/NAD(+) Ratio.
Antioxidants & Redox Signaling. Roč. 33, č. 12 (2020), s. 789-815. ISSN 1523-0864. E-ISSN 1557-7716
R&D Projects: GA ČR(CZ) GA16-06700S; GA ČR(CZ) GA17-01813S; GA ČR(CZ) GA20-00408S
Institutional support: RVO:67985823 ; RVO:61388971
Keywords : mitochondrial superoxide generation * pancreatic beta cells * glucose-stimulated insulin secretion * Complex I * NADH/NAD(+) ratio * fluorescence lifetime imaging
OECD category: Endocrinology and metabolism (including diabetes, hormones); Analytical chemistry (MBU-M)
Impact factor: 8.401, year: 2020
Method of publishing: Open access
https://www.liebertpub.com/doi/10.1089/ars.2019.7800
Permanent Link: http://hdl.handle.net/11104/0310854 - 2.0506716 - FGÚ 2020 RIV US eng J - Journal Article
Plecitá-Hlavatá, Lydie - Engstová, Hana - Ježek, Jan - Holendová, Blanka - Tauber, Jan - Petrásková, Lucie - Křen, Vladimír - Ježek, Petr
Potential of Mitochondria-Targeted Antioxidants to Prevent Oxidative Stress in Pancreatic beta-cells.
Oxidative Medicine and Cellular Longevity. Roč. 2019, č. 2019 (2019), č. článku 1826303. ISSN 1942-0900. E-ISSN 1942-0994
R&D Projects: GA ČR(CZ) GA16-06700S; GA ČR(CZ) GA17-01813S; GA ČR(CZ) GA18-00121S
Institutional support: RVO:67985823 ; RVO:61388971
Keywords : pancreatic beta cells * pancreatic islets * mitochondria- targeted antioxidants * oxidative stress * SkQ * S3QEL * S1QEL
OECD category: Cell biology; Physiology (including cytology) (MBU-M)
Impact factor: 5.076, year: 2019
Method of publishing: Open access
https://doi.org/10.1155/2019/1826303
Permanent Link: http://hdl.handle.net/11104/0297909 - 3.0496706 - FGÚ 2019 RIV CH eng J - Journal Article
Ježek, Jan - Plecitá-Hlavatá, Lydie - Ježek, Petr
Aglycemic HepG2 Cells Switch From Aminotransferase Glutaminolytic Pathway of Pyruvate Utilization to Complete Krebs Cycle at Hypoxia.
Frontiers in Endocrinology. Roč. 9, Oct 26 (2018), č. článku 637. ISSN 1664-2392. E-ISSN 1664-2392
R&D Projects: GA ČR(CZ) GA17-01813S
Institutional support: RVO:67985823
Keywords : hypoxia * HepG2 cells * aglycemia * oxidative phosphorylation * glycolysis * glutaminolysis
OECD category: Physiology (including cytology)
Impact factor: 3.634, year: 2018
Permanent Link: http://hdl.handle.net/11104/0289358 - 4.0489819 - FGÚ 2019 RIV GB eng J - Journal Article
Jabůrek, Martin - Ježek, Jan - Ježek, Petr
Cytoprotective activity of mitochondrial uncoupling protein‐2 in lung and spleen.
FEBS Open Bio. Roč. 8, č. 4 (2018), s. 692-701. ISSN 2211-5463. E-ISSN 2211-5463
R&D Projects: GA ČR GA15-02051S
Institutional support: RVO:67985823
Keywords : antioxidative synergy * cytoprotection * mitochondrial phospholipase iPLA2 gamma * mitochondrial uncoupling protein UCP2 * protein carbonylation
OECD category: Biochemistry and molecular biology
Impact factor: 1.959, year: 2018
Permanent Link: http://hdl.handle.net/11104/0284159 - 5.0454395 - FGÚ 2016 RIV US eng J - Journal Article
Plecitá-Hlavatá, Lydie - Ježek, Jan - Ježek, Petr
Aglycemia keeps mitochondrial oxidative phosphorylation under hypoxic conditions in HepG2 cells.
Journal of Bioenergetics and Biomembranes. Roč. 47, č. 6 (2015), s. 467-476. ISSN 0145-479X. E-ISSN 1573-6881
R&D Projects: GA ČR(CZ) GAP302/10/0346; GA ČR(CZ) GA13-02033S; GA MŠMT(CZ) LH11055
Institutional support: RVO:67985823
Keywords : cancer mitochondria * non-canonical response to hypoxia * hypoxia-inducible factor * glutaminolysis * HepG2 cells
Subject RIV: ED - Physiology
Impact factor: 2.080, year: 2015
Permanent Link: http://hdl.handle.net/11104/0255080 - 6.0451864 - FGÚ 2016 RIV US eng J - Journal Article
Ježek, Jan - Dlasková, Andrea - Zelenka, Jaroslav - Jabůrek, Martin - Ježek, Petr
H2O2-Activated Mitochondrial Phospholipase iPLA2 gamma Prevents Lipotoxic Oxidative Stress in Synergy with UCP2, Amplifies Signaling via G-Protein-Coupled Receptor GPR40, and Regulates Insulin Secretion in Pancreatic beta-Cells.
Antioxidants & Redox Signaling. Roč. 23, č. 12 (2015), s. 958-972. ISSN 1523-0864. E-ISSN 1557-7716
R&D Projects: GA ČR(CZ) GPP303/11/P320; GA ČR(CZ) GA13-02033S; GA ČR(CZ) GA13-06666S; GA ČR GA15-02051S
Institutional support: RVO:67985823
Keywords : mitochondrial phospholipase iPLA2 gamma * uncoupling protein UCP2 * G-protein coupled receptor - 40 * glucose-stimulated insulin secretion * pancreatic beta cells
Subject RIV: FB - Endocrinology, Diabetology, Metabolism, Nutrition
Impact factor: 7.093, year: 2015
Permanent Link: http://hdl.handle.net/11104/0252926 - 7.0428036 - FGÚ 2015 RIV CZ eng J - Journal Article
Ježek, Petr - Olejár, Tomáš - Smolková, Katarína - Ježek, Jan - Dlasková, Andrea - Plecitá-Hlavatá, Lydie - Zelenka, Jaroslav - Špaček, Tomáš - Engstová, Hana - Reguera Pajuelo, David - Jabůrek, Martin
Antioxidant and regulatory role of mitochondrial uncoupling protein UCP2 in pancreatic beta-cells.
Physiological Research. Roč. 63, Suppl.1 (2014), S73-S91. ISSN 0862-8408. E-ISSN 1802-9973
R&D Projects: GA ČR(CZ) GAP302/10/0346; GA ČR(CZ) GAP305/12/1247; GA ČR(CZ) GPP304/10/P204; GA MŠMT(CZ) EE2.3.30.0025
Institutional support: RVO:67985823
Keywords : mitochondria * uncoupling protein UCP2 * pancreatic beta-cells * reactive oxygen species * glucose-stimulated insulin secretion
Subject RIV: EA - Cell Biology
Impact factor: 1.293, year: 2014
Permanent Link: http://hdl.handle.net/11104/0233445 - 8.0391725 - FGÚ 2014 RIV GB eng J - Journal Article
Jabůrek, Martin - Ježek, Jan - Zelenka, Jaroslav - Ježek, Petr
Antioxidant activity by a synergy of redox-sensitive mitochondrial phospholipase A2 and uncoupling protein-2 in lung and spleen.
International Journal of Biochemistry and Cell Biology. Roč. 45, č. 4 (2013), s. 816-825. ISSN 1357-2725. E-ISSN 1878-5875
R&D Projects: GA ČR(CZ) GAP302/10/0346; GA ČR(CZ) GPP303/11/P320; GA MŠMT(CZ) ME09018
Institutional research plan: CEZ:AV0Z50110509
Institutional support: RVO:67985823
Keywords : mitochondrial uncoupling protein UCP2 * mitochondrial phospholipase A(2) isoform gamma * mitochondrial oxidative stress attenuation * fatty acid * antioxidant mechanism
Subject RIV: ED - Physiology
Impact factor: 4.240, year: 2013
Permanent Link: http://hdl.handle.net/11104/0220691 - 9.0355107 - FGÚ 2011 RIV US eng J - Journal Article
Gabrielová, E. - Jabůrek, Martin - Gažák, Radek - Vostálová, J. - Ježek, Jan - Křen, Vladimír - Modrianský, M.
Dehydrosilybin attenuates the production of ROS in rat cardiomyocyte mitochondria with an uncoupler-like mechanism.
Journal of Bioenergetics and Biomembranes. Roč. 42, č. 6 (2010), s. 499-509. ISSN 0145-479X. E-ISSN 1573-6881
R&D Projects: GA ČR(CZ) GA303/08/0658
Institutional research plan: CEZ:AV0Z50110509; CEZ:AV0Z50200510
Keywords : Reactive oxygen species * Cardiomyocytes * Dehydrosilybin
Subject RIV: CE - Biochemistry
Impact factor: 3.637, year: 2010
Permanent Link: http://hdl.handle.net/11104/0193950 - 10.0355105 - FGÚ 2011 RIV CZ eng J - Journal Article
Ježek, Jan - Jabůrek, Martin - Zelenka, Jaroslav - Ježek, Petr
Mitochondrial phospholipase A2 activated by reactive oxygen species in heart mitochondria induces mild uncoupling.
Physiological Research. Roč. 59, č. 5 (2010), s. 737-747. ISSN 0862-8408. E-ISSN 1802-9973
R&D Projects: GA ČR(CZ) GA303/07/0105; GA MŠMT ME09018; GA AV ČR(CZ) KJB500110902
Institutional research plan: CEZ:AV0Z50110509
Keywords : Heart mitochondrial phospholipase A2 * Fatty Acids * Adenine nucleotide translocase
Subject RIV: ED - Physiology
Impact factor: 1.646, year: 2010
Permanent Link: http://hdl.handle.net/11104/0193948