Search results

  1. 1.
    0506413 - BFÚ 2020 RIV US eng J - Journal Article
    Zajac, Juraj - Kostrhunová, Hana - Novohradský, Vojtěch - Vrána, Oldřich - Raveendran, R. - Gibson, D. - Kašpárková, J. - Brabec, Viktor
    Potentiation of mitochondrial dysfunction in tumor cells by conjugates of metabolic modulator dichloroacetate with a Pt(IV) derivative of oxaliplatin.
    Journal of Inorganic Biochemistry. Roč. 156, MAR 2016 (2016), s. 89-97. ISSN 0162-0134. E-ISSN 1873-3344
    R&D Projects: GA ČR(CZ) GA14-21053S; GA MŠMT(CZ) LH14317; GA MŠMT(CZ) LD14019
    Institutional support: RVO:68081707
    Keywords : in-vitro cytotoxicity * platinum(iv) complexes * antitumor-activity * increases sensitivity
    OECD category: Biochemistry and molecular biology
    Impact factor: 3.348, year: 2016
    Method of publishing: Limited access
    https://www.sciencedirect.com/science/article/pii/S0162013415301331?via%3Dihub
    Permanent Link: http://hdl.handle.net/11104/0297657
     
     
  2. 2.
    0471985 - BFÚ 2022 GB eng J - Journal Article
    Brabec, Viktor - Vrána, Oldřich - Nováková, Olga - Kašpárková, Jana
    Comment on ´Delivering a photosensitive transplatin prodrug to overcome cisplatin drug resistance´ by H. Song, W. Li, R. Qi, L. Yan, X. Jing, M. Zheng and H. Xiao, Chem. Commun., 2015, 51, 11493.
    2016. Chemical Communications. Roč. 52, č. 21 (2016), s. 4096-4098. ISSN 1359-7345. E-ISSN 1364-548X
    Institutional support: RVO:68081707
    Keywords : interstrand cross-links * dna * platinum
    OECD category: Physical chemistry
    Impact factor: 6.319, year: 2016
    Method of publishing: Limited access
    https://pubs.rsc.org/en/content/articlelanding/2016/CC/C5CC09589A
    Permanent Link: http://hdl.handle.net/11104/0269344
     
     
  3. 3.
    0471974 - BFÚ 2017 RIV DE eng J - Journal Article
    Vrána, Oldřich - Novohradský, Vojtěch - Medrikova, Z. - Burdikova, J. - Stuchlíková, O. - Kašpárková, Jana - Brabec, Viktor
    Internalization of Ineffective Platinum Complex in Nanocapsules Renders It Cytotoxic.
    Chemistry - A European Journal. Roč. 22, č. 8 (2016), s. 2728-2735. ISSN 0947-6539. E-ISSN 1521-3765
    R&D Projects: GA ČR(CZ) GA14-21053S
    Institutional support: RVO:68081707
    Keywords : interstrand cross-links * dna-adducts * cisplatin nanocapsules
    Subject RIV: BO - Biophysics
    Impact factor: 5.317, year: 2016
    Permanent Link: http://hdl.handle.net/11104/0269333
     
     
  4. 4.
    0471967 - BFÚ 2017 RIV DE eng J - Journal Article
    Medrikova, Z. - Novohradský, Vojtěch - Zajac, Juraj - Vrána, Oldřich - Kašpárková, Jana - Bakandritsos, A. - Petr, M. - Zbořil, R. - Brabec, Viktor
    Enhancing Tumor Cell Response to Chemotherapy through the Targeted Delivery of Platinum Drugs Mediated by Highly Stable, Multifunctional Carboxymethylcellulose-Coated Magnetic Nanoparticles.
    Chemistry - A European Journal. Roč. 22, č. 28 (2016), s. 9750-9759. ISSN 0947-6539. E-ISSN 1521-3765
    R&D Projects: GA MŠMT(CZ) LH14317; GA ČR(CZ) GA14-21053S
    Institutional support: RVO:68081707
    Keywords : iron-oxide nanoparticles * maghemite nanoparticles * nanocrystal clusters * anticancer drugs
    Subject RIV: BO - Biophysics
    Impact factor: 5.317, year: 2016
    Permanent Link: http://hdl.handle.net/11104/0269327
     
     
  5. 5.
    0446237 - BFÚ 2016 RIV US eng J - Journal Article
    Novohradský, Vojtěch - Zerzánková, Lenka - Štěpánková, Jana - Vrána, Oldřich - Raveendran, R. - Gibson, D. - Kašpárková, Jana - Brabec, Viktor
    New insights into the molecular and epigenetic effects of antitumor Pt(IV)-valproic acid conjugates in human ovarian cancer cells.
    Biochemical Pharmacology. Roč. 95, č. 3 (2015), s. 133-144. ISSN 0006-2952. E-ISSN 1873-2968
    R&D Projects: GA ČR(CZ) GA14-21053S; GA MŠMT(CZ) LD14019
    Institutional support: RVO:68081707
    Keywords : HISTONE DEACETYLASE INHIBITORS * MALIGNANT PLEURAL MESOTHELIOMA * VALPROIC ACID
    Subject RIV: BO - Biophysics
    Impact factor: 5.091, year: 2015
    Permanent Link: http://hdl.handle.net/11104/0248226
     
     
  6. 6.
    0439813 - BFÚ 2015 RIV US eng J - Journal Article
    Liu, Z. - Habtemariam, A. - Pizarro, A.M. - Fletcher, S.A. - Kisová, Anna - Vrána, Oldřich - Salassa, L. - Bruijnincx, P.C.A. - Clarkson, G.J. - Brabec, Viktor - Sadler, P. J.
    Organometallic Half-Sandwich Iridium Anticancer Complexes.
    Journal of Medicinal Chemistry. Roč. 54, č. 8 (2011), 3011-3026. ISSN 0022-2623. E-ISSN 1520-4804
    R&D Projects: GA ČR(CZ) GPP303/11/P047; GA ČR(CZ) GAP301/10/0598
    Keywords : RUTHENIUM(II) ARENE COMPLEXES * CANCER-CELL CYTOTOXICITY * DNA-BINDING PROPERTIES
    Subject RIV: BO - Biophysics
    Impact factor: 5.248, year: 2011
    Permanent Link: http://hdl.handle.net/11104/0243028
     
     
  7. 7.
    0435977 - BFÚ 2015 RIV US eng J - Journal Article
    Vaverková, V. - Vrána, Oldřich - Adam, V. - Pekárek, T. - Jampílek, J. - Babula, P.
    The Study of Naphthoquinones and Their Complexes with DNA by Using Raman Spectroscopy and Surface Enhanced Raman Spectroscopy: New Insight into Interactions of DNA with Plant Secondary Metabolites.
    BioMed Research International. Roč. 2014, June (2014). ISSN 2314-6133. E-ISSN 2314-6141
    Institutional support: RVO:68081707
    Keywords : CALF-THYMUS DNA * FLUORESCENT SYMMETRIC PHENAZINES * VITAMIN-K CYCLE
    Subject RIV: BO - Biophysics
    Impact factor: 1.579, year: 2014
    Permanent Link: http://hdl.handle.net/11104/0239821
     
     
  8. 8.
    0435475 - BFÚ 2015 RIV US eng J - Journal Article
    Novohradský, Vojtěch - Zerzánková, Lenka - Štěpánková, Jana - Vrána, Oldřich - Raveendran, R. - Gibson, D. - Kašpárková, Jana - Brabec, Viktor
    Antitumor platinum(IV) derivatives of oxaliplatin with axial valproato ligands.
    Journal of Inorganic Biochemistry. Roč. 140, NOV2014 (2014), s. 72-79. ISSN 0162-0134. E-ISSN 1873-3344
    R&D Projects: GA ČR(CZ) GA14-21053S
    Institutional support: RVO:68081707
    Keywords : Platinum(IV) prodrugs * Anticancer * Histone deacetylase
    Subject RIV: BO - Biophysics
    Impact factor: 3.444, year: 2014
    Permanent Link: http://hdl.handle.net/11104/0239852
     
     
  9. 9.
    0435470 - BFÚ 2015 FR eng J - Journal Article
    Nováková, Olga - Lišková, Barbora - Vystrčilová, Jana - Suchánková, Tereza - Vrána, Oldřich - Starha, P. - Trávníček, Z. - Brabec, Viktor
    Conformation and recognition of DNA damaged by antitumor cis-dichlorido platinum(II) complex of CDK inhibitor bohemine.
    European Journal of Medicinal Chemistry. Roč. 78, MAY2014 (2014), s. 54-64. ISSN 0223-5234. E-ISSN 1768-3254
    R&D Projects: GA ČR(CZ) GA13-08273S
    Institutional support: RVO:68081707
    Keywords : Antitumor * Platinum * DNA
    Subject RIV: BO - Biophysics
    Impact factor: 3.447, year: 2014
    Permanent Link: http://hdl.handle.net/11104/0239338
     
     
  10. 10.
    0394814 - BFÚ 2014 RIV DE eng J - Journal Article
    Muchová, T. - Prachařová, J. - Štarha, P. - Olivová, R. - Vrána, Oldřich - Benešová, B. - Kašpárková, J. - Trávníček, Z. - Brabec, Viktor
    Insight into the toxic effects of cis-dichloridoplatinum(II) complexes containing 7-azaindole halogeno derivatives in tumor cells.
    Journal of Biological Inorganic Chemistry. Roč. 18, č. 5 (2013), s. 579-589. ISSN 0949-8257. E-ISSN 1432-1327
    R&D Projects: GA ČR(CZ) GAP301/10/0598; GA MŠMT(CZ) LH13096
    Institutional research plan: CEZ:AV0Z50040702
    Institutional support: RVO:68081707
    Keywords : CELLULAR-RESPONSE * LUNG-CANCER * PLATINUM(II)
    Subject RIV: BO - Biophysics
    Impact factor: 3.164, year: 2013
    Permanent Link: http://hdl.handle.net/11104/0222996
     
     

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