Search results

  1. 1.
    0510201 - BFÚ 2020 RIV GB eng J - Journal Article
    Lukášová, Emilie - Řezáčová, M. - Bačíková, Alena - Sebejova, L. - Vávrová, J. - Kozubek, Stanislav
    Distinct cellular responses to replication stress leading to apoptosis or senescence.
    FEBS Open Bio. Roč. 9, č. 5 (2019), s. 870-890. ISSN 2211-5463. E-ISSN 2211-5463
    R&D Projects: GA ČR GBP302/12/G157; GA MZd NV16-29835A
    Institutional support: RVO:68081707
    Keywords : oncogene-induced senescence * dna-damage response * h2ax phosphorylation * cancer-cells * atr * chk1
    OECD category: Biochemistry and molecular biology
    Impact factor: 2.231, year: 2019
    Method of publishing: Open access
    https://febs.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/2211-5463.12632
    Permanent Link: http://hdl.handle.net/11104/0300726
     
     
  2. 2.
    0507904 - FZÚ 2020 RIV US eng J - Journal Article
    Kratochvílová, Irena - Kopečná, Olga - Bačíková, Alena - Pagáčová, Eva - Falková, Iva - Follett, S.E. - Elliott, K.W. - Varga, K. - Golan, Martin - Falk, Martin
    Changes in cryopreserved cell nuclei serve as indicators of processes during freezing and thawing.
    Langmuir. Roč. 35, č. 23 (2019), s. 7496-7508. ISSN 0743-7463
    R&D Projects: GA MŠk EF16_019/0000760; GA MŠk EF16_013/0001406; GA MŠk(CZ) LO1409; GA ČR(CZ) GA15-05095S; GA ČR(CZ) GA16-12454S; GA MZd NV16-29835A
    Grant - others: OP VVV - SOLID21(XE) CZ.02.1.01/0.0/0.0/16_019/0000760; OP VVV - SAFMAT(XE) CZ.02.1.01/0.0/0.0/16_013/0001406
    Institutional support: RVO:68378271 ; RVO:68081707
    Keywords : cryopreservation * chromatin condensation * cell nuclei membrane
    OECD category: Biophysics; Physical chemistry (BFU-R)
    Impact factor: 3.557, year: 2019
    Method of publishing: Limited access
    https://doi.org/10.1021/acs.langmuir.8b02742
    Permanent Link: http://hdl.handle.net/11104/0298867
     
     
  3. 3.
    0501639 - BFÚ 2019 RIV CH eng J - Journal Article
    Bobkova, E. - Depeš, Daniel - Lee, J.H. - Jezkova, L. - Falková, Iva - Pagáčová, Eva - Kopečná, Olga - Zadneprianetc, M. - Bačíková, Alena - Kulikova, E. - Smirnova, E. - Bulanova, T. - Boreyko, A. - Krasavin, E. - Wenz, F. - Bestvater, F. - Hildenbrand, G. - Hausmann, M. - Falk, Martin
    Recruitment of 53BP1 Proteins for DNA Repair and Persistence of Repair Clusters Differ for Cell Types as Detected by Single Molecule Localization Microscopy.
    International Journal of Molecular Sciences. Roč. 19, č. 12 (2018), č. článku 3713. E-ISSN 1422-0067
    R&D Projects: GA ČR(CZ) GA16-12454S; GA MZd NV16-29835A
    Institutional support: RVO:68081707
    Keywords : strand-break repair * high-let * alternative pathways * h2ax phosphorylation
    OECD category: Biochemistry and molecular biology
    Impact factor: 4.183, year: 2018
    Permanent Link: http://hdl.handle.net/11104/0293634
     
     
  4. 4.
    0495086 - BFÚ 2019 RIV DE eng J - Journal Article
    Depeš, Daniel - Lee, J.H. - Bobkova, E. - Jezkova, L. - Falková, Iva - Bestvater, F. - Pagáčová, Eva - Kopečná, Olga - Zadneprianetc, M. - Bačíková, Alena - Kulikova, E. - Smirnova, E. - Bulanova, T. - Boreyko, A. - Krasavin, E. - Hausmann, M. - Falk, Martin
    Single-molecule localization microscopy as a promising tool for gamma H2AX/53BP1 foci exploration.
    European Physical Journal D. Roč. 72, č. 9 (2018), č. článku 158. ISSN 1434-6060. E-ISSN 1434-6079
    R&D Projects: GA ČR(CZ) GA16-12454S; GA MZd NV16-29835A
    Institutional support: RVO:68081707
    Keywords : double-strand breaks * high-let-irradiation * precision distance microscopy * complex cell responses * linear-energy-transfer * clustered dna-damage * beam cancer-therapy * chromatin-structure * nanoscopy techniques * electron-microscopy
    OECD category: Biochemistry and molecular biology
    Impact factor: 1.331, year: 2018
    Permanent Link: http://hdl.handle.net/11104/0288105
     
     
  5. 5.
    0494984 - BFÚ 2019 RIV GB eng J - Journal Article
    Falk, Martin - Falková, Iva - Kopečná, Olga - Bačíková, Alena - Pagáčová, Eva - Šimek, Daniel - Golan, Martin - Kozubek, Stanislav - Pekarová, Michaela - Follett, S.E. - Klejdus, B. - Elliott, K.W. - Varga, K. - Teplá, O. - Kratochvílová, Irena
    Chromatin architecture changes and DNA replication fork collapse are critical features in cryopreserved cells that are differentially controlled by cryoprotectants.
    Scientific Reports. Roč. 8, OCT 2 2018 (2018), č. článku 14694. ISSN 2045-2322. E-ISSN 2045-2322
    R&D Projects: GA MZd NV16-29835A; GA ČR(CZ) GA16-12454S; GA MŠk(CZ) LO1409
    Grant - others: FUNBIO(XE) CZ.2.16/3.1.00/21568
    Institutional support: RVO:68081707 ; RVO:68378271
    Keywords : human spermatozoa * oxidative-stress * damage response * repair * trehalose * integrity * dynamics * sperm * fragmentation * instability
    OECD category: Cell biology; Biophysics (FZU-D)
    Impact factor: 4.011, year: 2018
    Permanent Link: http://hdl.handle.net/11104/0288034
    FileDownloadSizeCommentaryVersionAccess
    0494984.pdf83.9 MBCC licencePublisher’s postprintopen-access
     
     
  6. 6.
    0485752 - BFÚ 2018 GB eng J - Journal Article
    Lukášová, Emilie - Kovařík, Aleš - Bačíková, Alena - Falk, Martin - Kozubek, Stanislav
    Loss of lamin B receptor is necessary to induce cellular senescence.
    Biochemical Journal. Roč. 474 (2017), s. 281-300. ISSN 0264-6021. E-ISSN 1470-8728
    R&D Projects: GA ČR GBP302/12/G157; GA ČR GBP501/12/G090
    Institutional support: RVO:68081707
    Keywords : oncogene-induced senescence * inner nuclear-membrane * dna-damage response
    OECD category: Genetics and heredity (medical genetics to be 3)
    Impact factor: 3.857, year: 2017
    Permanent Link: http://hdl.handle.net/11104/0280696
     
     
  7. 7.
    0485555 - BFÚ 2018 RIV DE eng J - Journal Article
    Falk, Martin - Hořáková, Z. - Svobodová, M. - Masařík, M. - Kopečná, Olga - Gumulec, J. - Raudenská, M. - Depeš, Daniel - Bačíková, Alena - Falková, Iva - Binkova, H.
    gamma H2AX/53BP1 foci as a potential pre-treatment marker of HNSCC tumors radiosensitivity preliminary methodological study and discussion.
    European Physical Journal D. Roč. 71, č. 9 (2017), č. článku 241. ISSN 1434-6060. E-ISSN 1434-6079
    R&D Projects: GA ČR(CZ) GA16-12454S
    Institutional support: RVO:68081707
    Keywords : squamous-cell carcinoma * cancer-associated fibroblasts
    OECD category: Biochemistry and molecular biology
    Impact factor: 1.393, year: 2017
    Permanent Link: http://hdl.handle.net/11104/0280520
     
     
  8. 8.
    0471970 - BFÚ 2020 RIV US eng J - Journal Article
    Hofer, Michal - Falk, Martin - Komůrková, Denisa - Falková, Iva - Bačíková, Alena - Klejdus, B. - Pagáčová, Eva - Štefančíková, Lenka - Weiterová, Lenka - Angelis, Karel - Kozubek, Stanislav - Dušek, L. - Galbavy, S.
    Two New Faces of Amifostine: Protector from DNA Damage in Normal Cells and Inhibitor of DNA Repair in Cancer Cells.
    Journal of Medicinal Chemistry. Roč. 59, č. 7 (2016), s. 3003-3017. ISSN 0022-2623. E-ISSN 1520-4804
    R&D Projects: GA ČR GBP302/12/G157; GA ČR(CZ) GA16-12454S; GA MZd NV16-29835A; GA ČR GA16-01137S
    Institutional support: RVO:68081707 ; RVO:61389030
    Keywords : alternative splicing variant * order chromatin-structure
    OECD category: Pharmacology and pharmacy; Pharmacology and pharmacy (UEB-Q)
    Impact factor: 6.259, year: 2016
    Method of publishing: Limited access
    https://pubs.acs.org/doi/10.1021/acs.jmedchem.5b01628#
    Permanent Link: http://hdl.handle.net/11104/0269330
    FileDownloadSizeCommentaryVersionAccess
    03_Hofer_JMedChem_2016.pdf56.3 MBOtheropen-access
     
     
  9. 9.
    0440773 - ÚJF 2015 RIV US eng J - Journal Article
    Falk, Martin - Hausmann, M. - Lukášová, Emilie - Biswas, A. - Hildenbrand, G. - Davídková, Marie - Krasavin, E. - Kleibl, Z. - Falková, Iva - Ježková, L. - Štefančíková, Lenka - Ševčík, J. - Hofer, Michal - Bačíková, Alena - Matula, Pavel - Boreyko, A. - Vachelová, Jana - Michaelidesová, Anna - Kozubek, Stanislav
    Determining Omics Spatiotemporal Dimensions Using Exciting New Nanoscopy Techniques to Assess Complex Cell Responses to DNA Damage: Part B-Structuromics.
    Critical Reviews in Eukaryotic Gene Expression. Roč. 24, č. 3 (2014), s. 225-247. ISSN 1045-4403. E-ISSN 2162-6502
    R&D Projects: GA ČR GBP302/12/G157; GA ČR GAP302/10/1022; GA MŠk LD12039; GA MŠk LD12008; GA MŠk(XE) LM2011019
    Institutional support: RVO:68081707 ; RVO:61389005
    Keywords : omics * ionizing radiation * low-dose dilemma * biological complexity and variability * higher-order chromatin structure * DNA damage response * formation of chromosomal translocations * confocal microscopy * localization nanoscopy
    Subject RIV: BO - Biophysics; BO - Biophysics (BFU-R)
    Impact factor: 1.571, year: 2014
    Permanent Link: http://hdl.handle.net/11104/0243900
     
     
  10. 10.
    0424749 - BFÚ 2014 RIV GB eng J - Journal Article
    Ježková, L. - Falk, Martin - Falková, Iva - Davídková, Marie - Bačíková, Alena - Štefančíková, Lenka - Vachelová, Jana - Michaelidesová, Anna - Lukášová, Emilie - Boreyko, A. - Krasavin, E. - Kozubek, Stanislav
    Function of chromatin structure and dynamics in DNA damage, repair and misrepair: gamma-rays and protons in action.
    Applied Radiation and Isotopes. Roč. 83, SI (2014), s. 128-136. ISSN 0969-8043
    R&D Projects: GA MŠk(CZ) EE2.3.30.0030; GA ČR(CZ) GBP302/12/G157; GA ČR(CZ) GAP302/10/1022; GA ČR(CZ) GBP108/12/G108; GA MŠk(CZ) LD12039; GA MŠk(CZ) LD12008
    Institutional support: RVO:68081707 ; RVO:61389005
    Keywords : DNA double-strand breaks * Higher-order chromatin structure and DSB repair * Formation of chromosomal translocations
    Subject RIV: BO - Biophysics; BO - Biophysics (UJF-V)
    Impact factor: 1.231, year: 2014
    Permanent Link: http://hdl.handle.net/11104/0230775