Search results

  1. 1.
    0564278 - ÚOCHB 2023 FR eng A - Abstract
    Šnajdr, Ivan - Krečmerová, Marcela - Bell, B. - Alt, J. - Gori, S. - Rais, R. - Majer, Pavel - Slusher, B.
    Synthesis and biological activity of itaconate prodrugs.
    EFMC-ISMC 2022. 27th International Symposium on Medicinal Chemistry. Nice: Société de Chimie Thérapeutique, 2022, č. článku 146..
    [EFMC-ISMC 2022. International Symposium on Medicinal Chemistry /27./. 04.09.2022-08.09.2022, Nice]
    Institutional support: RVO:61388963
    Keywords : itaconates * prodrugs * inflammation
    OECD category: Medicinal chemistry
    Permanent Link: https://hdl.handle.net/11104/0335987

               
     
     
  2. 2.
    0557262 - ÚOCHB 2023 NL eng A - Abstract
    Peters, D. - Norris, L. - Tenora, Lukáš - Šnajdr, Ivan - Zhu, X. - Sakamoto, S. - Veeravalli, V. - Thomas, A. - Majer, Pavel - Rais, R. - Slusher, B.
    Discovery of IBD3540: A Novel Gut-Restricted Glutamate Carboxypeptidase II Inhibitor with Preclinical Anti-Colitis Activity.
    Journal of Crohns & Colitis. Oxford University Press. Roč. 16 (2022), I174-I175. ISSN 1873-9946. E-ISSN 1876-4479.
    [Congress of ECCO /17./. 16.02.2022-19.02.2022, online]
    Institutional support: RVO:61388963
    Keywords : glutamate carboxypeptidase
    OECD category: Biochemistry and molecular biology
    https://doi.org/10.1093/ecco-jcc/jjab232.197
    Permanent Link: http://hdl.handle.net/11104/0331342

               
     
     
  3. 3.
    0548469 - ÚOCHB 2022 CZ eng A - Abstract
    Hadzima, Martin - Houštecká, Radka - Pallová, Lenka - Hánová, Iva - Fanfrlík, Jindřich - Brynda, Jiří - Lepšík, Martin - Mertlíková-Kaiserová, Helena - Horn, Martin - Mareš, Michael - Majer, Pavel
    Design, Synthesis and Activity of Biomimetic Macrocyclic Inhibitors of Human Cathepsin D.
    Liblice 2021. 55th Advances in Organic, Bioorganic and Pharmaceutical Chemistry. Praha: Czech Chemical Society, 2021. s. 112.
    [Liblice 2021. Advances in Organic, Bioorganic and Pharmaceutical Chemistry /55./. 03.11.2021-06.11.2021, Špindlerův Mlýn]
    Institutional support: RVO:61388963
    Keywords : inhibitor * cathepsin * macrocycles * peptides * statine * synthesis
    OECD category: Medicinal chemistry
    Permanent Link: http://hdl.handle.net/11104/0324491

               
     
     
  4. 4.
    0547733 - ÚOCHB 2022 CZ eng A - Abstract
    Reiberger, Róbert - Radilová, Kateřina - Král, Michal - Majer, Pavel - Konvalinka, Jan - Kožíšek, Milan - Machara, Aleš
    Synthesis and In Vitro Evaluation of C-7 and C-8 Luteolin Derivatives as Influenza Endonuclease Inhibitors.
    Liblice 2021. 55th Advances in Organic, Bioorganic and Pharmaceutical Chemistry. Praha: Czech Chemical Society, 2021. s. 181.
    [Liblice 2021. Advances in Organic, Bioorganic and Pharmaceutical Chemistry /55./. 03.11.2021-06.11.2021, Špindlerův Mlýn]
    Institutional support: RVO:61388963
    OECD category: Biochemistry and molecular biology
    Permanent Link: http://hdl.handle.net/11104/0323916

               
     
     
  5. 5.
    0547731 - ÚOCHB 2022 CZ eng A - Abstract
    Zima, Václav - Radilová, Kateřina - Berenguer Albiñana, Carlos - Karlukova, Elena - Konvalinka, Jan - Brynda, Jiří - Fanfrlík, Jindřich - Weber, Jan - Majer, Pavel - Kožíšek, Milan - Machara, Aleš
    Unraveling the Anti-Influenza Effect of Flavonoids: Experimental Validation of Flavonoids as Endonuclease Inhibitors.
    Liblice 2021. 55th Advances in Organic, Bioorganic and Pharmaceutical Chemistry. Praha: Czech Chemical Society, 2021. s. 72.
    [Liblice 2021. Advances in Organic, Bioorganic and Pharmaceutical Chemistry /55./. 03.11.2021-06.11.2021, Špindlerův Mlýn]
    R&D Projects: GA MŠk(CZ) EF16_019/0000729; GA MŠk(CZ) LM2015064
    Institutional support: RVO:61388963
    OECD category: Biochemistry and molecular biology
    Permanent Link: http://hdl.handle.net/11104/0323912

               
     
     
  6. 6.
    0545193 - ÚOCHB 2022 US eng A - Abstract
    Lemberg, K. M. - Aguilar, J. M. H. - Alt, J. - Krečmerová, Marcela - Majer, Pavel - Rais, R. - Slusher, B.
    A novel protide purine antimetabolite combines with the prodrug glutamine antagonist JHU395 in preclinical models of Ras-driven sarcomas.
    Cancer Research. American Association for Cancer Research. Roč. 81, č. 13 (2021). ISSN 0008-5472. E-ISSN 1538-7445.
    [AACR Annual Meeting 2021. 10.04.2021-15.04.2021, online]
    Institutional support: RVO:61388963
    OECD category: Organic chemistry
    https://doi.org/10.1158/1538-7445.AM2021-1293
    Permanent Link: http://hdl.handle.net/11104/0321931

               
     
     
  7. 7.
    0521281 - ÚOCHB 2020 US eng A - Abstract
    Tenora, Lukáš - Novotná, Kateřina - Jančařík, Andrej - Rais, R. - Alt, J. - Slusher, B. S. - Majer, Pavel
    Prodrugs of 6-Diazo-5-oxo-L-norleucine: Strategy for Delivery in Brain and Potencial Treatment of Lymphoma.
    Boulder Peptide Symposium 2019. Boulder: Boulder Peptide Society, 2019.
    [Boulder Peptide Symposium 2019. 23.09.2019-26.09.2019, Boulder]
    Institutional support: RVO:61388963
    Keywords : prodrugs * 6-diazo-5-oxo-L-norleucine * brain targeting
    OECD category: Medicinal chemistry
    Permanent Link: http://hdl.handle.net/11104/0305914

               
     
     
  8. 8.
    0521273 - ÚOCHB 2020 GR eng A - Abstract
    Tenora, Lukáš - Novotná, Kateřina - Jančařík, Andrej - Rais, R. - Alt, J. - Slusher, B. S. - Majer, Pavel
    Prodrugs of 6-Diazo-5-oxo-L-norleucine: Strategy for Delivery in Brain and Potencial Treatment of Lymphoma.
    EFMC-ASMC’19. 8th EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry. Athens: European Federation for Medicinal Chemistry, 2019. s. 294.
    [EFMC-ASMC’19. EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry /8./. 01.09.2019-05.09.2019, Athens]
    Institutional support: RVO:61388963
    Keywords : prodrugs * 6-diazo-5-oxo-L-norleucine * brain targeting
    OECD category: Medicinal chemistry
    Permanent Link: http://hdl.handle.net/11104/0305911

               
     
     
  9. 9.
    0521256 - ÚOCHB 2020 US eng A - Abstract
    Šnajdr, Ivan - Jančařík, Andrej - Tenora, Lukáš - Nedelcovych, M. - Alt, J. - Englert, J. - Rojas, C. - Le, A. - Elgogary, A. - Tan, J. - Monincová, Lenka - Pate, K. - Adams, R. - Ferraris, D. - Powell, J. - Majer, Pavel - Rais, R. - Slusher, B. S.
    Prodrugs of 6-Diazo-5-oxo-L-norleucine (DON) with Enhanced CSF Delivery in Monkeys as a Potential Treatment for Glioblastoma.
    Boulder Peptide Symposium 2019. Boulder: Boulder Peptide Society, 2019.
    [Boulder Peptide Symposium 2019. 23.09.2019-26.09.2019, Boulder]
    Institutional support: RVO:61388963
    Keywords : DON * glioblastoma * prodrugs
    OECD category: Medicinal chemistry
    Permanent Link: http://hdl.handle.net/11104/0305888

               
     
     
  10. 10.
    0521237 - ÚOCHB 2020 GR eng A - Abstract
    Šnajdr, Ivan - Jančařík, Andrej - Tenora, Lukáš - Nedelcovych, M. - Alt, J. - Englert, J. - Rojas, C. - Le, A. - Elgogary, A. - Tan, J. - Monincová, Lenka - Pate, K. - Adams, R. - Ferraris, D. - Powell, J. - Majer, Pavel - Rais, R. - Slusher, B. S.
    Prodrugs of 6-Diazo-5-oxo-L-norleucine (DON) with Enhanced CSF Delivery in Monkeys as a Potential Treatment for Glioblastoma.
    EFMC-ASMC’19. 8th EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry. Athens: European Federation for Medicinal Chemistry, 2019. s. 352.
    [EFMC-ASMC’19. EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry /8./. 01.09.2019-05.09.2019, Athens]
    Institutional support: RVO:61388963
    Keywords : DON * glioblastoma * prodrugs
    OECD category: Medicinal chemistry
    Permanent Link: http://hdl.handle.net/11104/0305872

               
     
     

  This site uses cookies to make them easier to browse. Learn more about how we use cookies.