Search results
- 1.0564278 - ÚOCHB 2023 FR eng A - Abstract
Šnajdr, Ivan - Krečmerová, Marcela - Bell, B. - Alt, J. - Gori, S. - Rais, R. - Majer, Pavel - Slusher, B.
Synthesis and biological activity of itaconate prodrugs.
EFMC-ISMC 2022. 27th International Symposium on Medicinal Chemistry. Nice: Société de Chimie Thérapeutique, 2022, č. článku 146..
[EFMC-ISMC 2022. International Symposium on Medicinal Chemistry /27./. 04.09.2022-08.09.2022, Nice]
Institutional support: RVO:61388963
Keywords : itaconates * prodrugs * inflammation
OECD category: Medicinal chemistry
Permanent Link: https://hdl.handle.net/11104/0335987 - 2.0557262 - ÚOCHB 2023 NL eng A - Abstract
Peters, D. - Norris, L. - Tenora, Lukáš - Šnajdr, Ivan - Zhu, X. - Sakamoto, S. - Veeravalli, V. - Thomas, A. - Majer, Pavel - Rais, R. - Slusher, B.
Discovery of IBD3540: A Novel Gut-Restricted Glutamate Carboxypeptidase II Inhibitor with Preclinical Anti-Colitis Activity.
Journal of Crohns & Colitis. Oxford University Press. Roč. 16 (2022), I174-I175. ISSN 1873-9946. E-ISSN 1876-4479.
[Congress of ECCO /17./. 16.02.2022-19.02.2022, online]
Institutional support: RVO:61388963
Keywords : glutamate carboxypeptidase
OECD category: Biochemistry and molecular biology
https://doi.org/10.1093/ecco-jcc/jjab232.197
Permanent Link: http://hdl.handle.net/11104/0331342 - 3.0548469 - ÚOCHB 2022 CZ eng A - Abstract
Hadzima, Martin - Houštecká, Radka - Pallová, Lenka - Hánová, Iva - Fanfrlík, Jindřich - Brynda, Jiří - Lepšík, Martin - Mertlíková-Kaiserová, Helena - Horn, Martin - Mareš, Michael - Majer, Pavel
Design, Synthesis and Activity of Biomimetic Macrocyclic Inhibitors of Human Cathepsin D.
Liblice 2021. 55th Advances in Organic, Bioorganic and Pharmaceutical Chemistry. Praha: Czech Chemical Society, 2021. s. 112.
[Liblice 2021. Advances in Organic, Bioorganic and Pharmaceutical Chemistry /55./. 03.11.2021-06.11.2021, Špindlerův Mlýn]
Institutional support: RVO:61388963
Keywords : inhibitor * cathepsin * macrocycles * peptides * statine * synthesis
OECD category: Medicinal chemistry
Permanent Link: http://hdl.handle.net/11104/0324491 - 4.0547733 - ÚOCHB 2022 CZ eng A - Abstract
Reiberger, Róbert - Radilová, Kateřina - Král, Michal - Majer, Pavel - Konvalinka, Jan - Kožíšek, Milan - Machara, Aleš
Synthesis and In Vitro Evaluation of C-7 and C-8 Luteolin Derivatives as Influenza Endonuclease Inhibitors.
Liblice 2021. 55th Advances in Organic, Bioorganic and Pharmaceutical Chemistry. Praha: Czech Chemical Society, 2021. s. 181.
[Liblice 2021. Advances in Organic, Bioorganic and Pharmaceutical Chemistry /55./. 03.11.2021-06.11.2021, Špindlerův Mlýn]
Institutional support: RVO:61388963
OECD category: Biochemistry and molecular biology
Permanent Link: http://hdl.handle.net/11104/0323916 - 5.0547731 - ÚOCHB 2022 CZ eng A - Abstract
Zima, Václav - Radilová, Kateřina - Berenguer Albiñana, Carlos - Karlukova, Elena - Konvalinka, Jan - Brynda, Jiří - Fanfrlík, Jindřich - Weber, Jan - Majer, Pavel - Kožíšek, Milan - Machara, Aleš
Unraveling the Anti-Influenza Effect of Flavonoids: Experimental Validation of Flavonoids as Endonuclease Inhibitors.
Liblice 2021. 55th Advances in Organic, Bioorganic and Pharmaceutical Chemistry. Praha: Czech Chemical Society, 2021. s. 72.
[Liblice 2021. Advances in Organic, Bioorganic and Pharmaceutical Chemistry /55./. 03.11.2021-06.11.2021, Špindlerův Mlýn]
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) LM2015064
Institutional support: RVO:61388963
OECD category: Biochemistry and molecular biology
Permanent Link: http://hdl.handle.net/11104/0323912 - 6.0545193 - ÚOCHB 2022 US eng A - Abstract
Lemberg, K. M. - Aguilar, J. M. H. - Alt, J. - Krečmerová, Marcela - Majer, Pavel - Rais, R. - Slusher, B.
A novel protide purine antimetabolite combines with the prodrug glutamine antagonist JHU395 in preclinical models of Ras-driven sarcomas.
Cancer Research. American Association for Cancer Research. Roč. 81, č. 13 (2021). ISSN 0008-5472. E-ISSN 1538-7445.
[AACR Annual Meeting 2021. 10.04.2021-15.04.2021, online]
Institutional support: RVO:61388963
OECD category: Organic chemistry
https://doi.org/10.1158/1538-7445.AM2021-1293
Permanent Link: http://hdl.handle.net/11104/0321931 - 7.0521281 - ÚOCHB 2020 US eng A - Abstract
Tenora, Lukáš - Novotná, Kateřina - Jančařík, Andrej - Rais, R. - Alt, J. - Slusher, B. S. - Majer, Pavel
Prodrugs of 6-Diazo-5-oxo-L-norleucine: Strategy for Delivery in Brain and Potencial Treatment of Lymphoma.
Boulder Peptide Symposium 2019. Boulder: Boulder Peptide Society, 2019.
[Boulder Peptide Symposium 2019. 23.09.2019-26.09.2019, Boulder]
Institutional support: RVO:61388963
Keywords : prodrugs * 6-diazo-5-oxo-L-norleucine * brain targeting
OECD category: Medicinal chemistry
Permanent Link: http://hdl.handle.net/11104/0305914 - 8.0521273 - ÚOCHB 2020 GR eng A - Abstract
Tenora, Lukáš - Novotná, Kateřina - Jančařík, Andrej - Rais, R. - Alt, J. - Slusher, B. S. - Majer, Pavel
Prodrugs of 6-Diazo-5-oxo-L-norleucine: Strategy for Delivery in Brain and Potencial Treatment of Lymphoma.
EFMC-ASMC’19. 8th EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry. Athens: European Federation for Medicinal Chemistry, 2019. s. 294.
[EFMC-ASMC’19. EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry /8./. 01.09.2019-05.09.2019, Athens]
Institutional support: RVO:61388963
Keywords : prodrugs * 6-diazo-5-oxo-L-norleucine * brain targeting
OECD category: Medicinal chemistry
Permanent Link: http://hdl.handle.net/11104/0305911 - 9.0521256 - ÚOCHB 2020 US eng A - Abstract
Šnajdr, Ivan - Jančařík, Andrej - Tenora, Lukáš - Nedelcovych, M. - Alt, J. - Englert, J. - Rojas, C. - Le, A. - Elgogary, A. - Tan, J. - Monincová, Lenka - Pate, K. - Adams, R. - Ferraris, D. - Powell, J. - Majer, Pavel - Rais, R. - Slusher, B. S.
Prodrugs of 6-Diazo-5-oxo-L-norleucine (DON) with Enhanced CSF Delivery in Monkeys as a Potential Treatment for Glioblastoma.
Boulder Peptide Symposium 2019. Boulder: Boulder Peptide Society, 2019.
[Boulder Peptide Symposium 2019. 23.09.2019-26.09.2019, Boulder]
Institutional support: RVO:61388963
Keywords : DON * glioblastoma * prodrugs
OECD category: Medicinal chemistry
Permanent Link: http://hdl.handle.net/11104/0305888 - 10.0521237 - ÚOCHB 2020 GR eng A - Abstract
Šnajdr, Ivan - Jančařík, Andrej - Tenora, Lukáš - Nedelcovych, M. - Alt, J. - Englert, J. - Rojas, C. - Le, A. - Elgogary, A. - Tan, J. - Monincová, Lenka - Pate, K. - Adams, R. - Ferraris, D. - Powell, J. - Majer, Pavel - Rais, R. - Slusher, B. S.
Prodrugs of 6-Diazo-5-oxo-L-norleucine (DON) with Enhanced CSF Delivery in Monkeys as a Potential Treatment for Glioblastoma.
EFMC-ASMC’19. 8th EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry. Athens: European Federation for Medicinal Chemistry, 2019. s. 352.
[EFMC-ASMC’19. EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry /8./. 01.09.2019-05.09.2019, Athens]
Institutional support: RVO:61388963
Keywords : DON * glioblastoma * prodrugs
OECD category: Medicinal chemistry
Permanent Link: http://hdl.handle.net/11104/0305872