Search results
- 1.0583349 - ÚOCHB 2025 RIV US eng J - Journal Article
Dhillon, Arun - Persson, B. D. - Volkov, A. N. - Sülzen, Hagen - Kádek, Alan - Pompach, Petr - Kereiche, Sami - Lepšík, Martin - Danskog, K. - Uetrecht, C. - Arnberg, N. - Zoll, Sebastian
Structural insights into the interaction between adenovirus C5 hexon and human lactoferrin.
Journal of Virology. Roč. 98, č. 3 (2024), č. článku e01576-23. ISSN 0022-538X. E-ISSN 1098-5514
R&D Projects: GA MŠMT LM2023042; GA MŠMT(CZ) EF18_046/0015974
Institutional support: RVO:61388963 ; RVO:61388971 ; RVO:86652036
Keywords : adenovirus * lactoferrin * cryo-EM * immune evasion * viral entry
OECD category: Virology (MBU-M)
Impact factor: 5.4, year: 2022
Method of publishing: Open access
https://doi.org/10.1128/jvi.01576-23
Permanent Link: https://hdl.handle.net/11104/0351321
Research data: ZENODO - 2.0582928 - ÚOCHB 2025 RIV US eng J - Journal Article
Pecina, Adam - Fanfrlík, Jindřich - Lepšík, Martin - Řezáč, Jan
SQM2.20: Semiempirical quantum-mechanical scoring function yields DFT-quality protein-ligand binding affinity predictions in minutes.
Nature Communications. Roč. 15, February (2024), č. článku 1127. E-ISSN 2041-1723
Research Infrastructure: e-INFRA CZ II - 90254
Institutional support: RVO:61388963
Keywords : NDDO approximations * free-energies * docking
Impact factor: 16.6, year: 2022
Method of publishing: Open access
https://doi.org/10.1038/s41467-024-45431-8
Permanent Link: https://hdl.handle.net/11104/0350971
Research data: ZENODO - 3.0574395 - ÚOCHB 2024 RIV DE eng J - Journal Article
Kuba, Miroslav - Khoroshyy, Petro - Lepšík, Martin - Kužmová, Erika - Kodr, David - Kraus, Tomáš - Hocek, Michal
Real-time Imaging of Nascent DNA in Live Cells by Monitoring the Fluorescence Lifetime of DNA-Incorporated Thiazole Orange-Modified Nucleotides.
Angewandte Chemie - International Edition. Roč. 62, č. 38 (2023), č. článku e202307548. ISSN 1433-7851. E-ISSN 1521-3773
R&D Projects: GA ČR(CZ) GX20-00885X
Institutional support: RVO:61388963
Keywords : DNA synthesis * fluorescence lifetime imaging microscopy * fluorophores * metabolic labelling * nucleotides
OECD category: Organic chemistry
Impact factor: 16.6, year: 2022
Method of publishing: Open access
https://doi.org/10.1002/anie.202307548
Permanent Link: https://hdl.handle.net/11104/0344723 - 4.0571224 - ÚOCHB 2024 RIV US eng J - Journal Article
Pávová, Marcela - Reyes Gutierrez, Paul Eduardo - Kozák, Jaroslav - Dobiaš, Juraj - Yurenko, Yevgen - Lepšík, Martin - Teplý, Filip - Weber, Jan
Helquat dyes targeting G-quadruplexes as a new class of anti-HIV-1 inhibitors.
Scientific Reports. Roč. 13, April (2023), č. článku 6096. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA MŠMT(CZ) LX22NPO5103
Research Infrastructure: e-INFRA CZ - 90140
Institutional support: RVO:61388963
Keywords : long terminal repeat * promoter * binding
OECD category: Virology
Impact factor: 4.6, year: 2022
Method of publishing: Open access
https://doi.org/10.1038/s41598-023-33263-3
Permanent Link: https://hdl.handle.net/11104/0342496File Download Size Commentary Version Access s41598-023-33263-3.pdf 1 1.9 MB Publisher’s postprint open-access - 5.0569104 - ÚOCHB 2024 RIV US eng J - Journal Article
Porkolab, V. - Lepšík, Martin - Ordanini, S. - St John, A. - Le Roy, A. - Thépaut, M. - Paci, E. - Ebel, C. - Bernardi, A. - Fieschi, F.
Powerful Avidity with a Limited Valency for Virus-Attachment Blockers on DC-SIGN: Combining Chelation and Statistical Rebinding with Structural Plasticity of the Receptor.
ACS Central Science. Roč. 9, č. 4 (2023), s. 709-718. ISSN 2374-7943. E-ISSN 2374-7951
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : lectin receptors * trans-infection * ligands
OECD category: Physical chemistry
Impact factor: 18.2, year: 2022
Method of publishing: Open access
https://doi.org/10.1021/acscentsci.2c01136
Permanent Link: https://hdl.handle.net/11104/0340429 - 6.0567034 - ÚOCHB 2024 RIV GB eng J - Journal Article
Fanfrlík, Jindřich - Brynda, Jiří - Kugler, Michael - Lepšík, Martin - Pospíšilová, Klára - Holub, Josef - Hnyk, Drahomír - Nekvinda, Jan - Grüner, Bohumír - Řezáčová, Pavlína
B-H⋯π and C-H⋯π interactions in protein-ligand complexes: carbonic anhydrase II inhibition by carborane sulfonamides.
Physical Chemistry Chemical Physics. Roč. 25, č. 3 (2023), s. 1728-1733. ISSN 1463-9076. E-ISSN 1463-9084
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA MŠMT LX22NPO5102; GA ČR(CZ) GA21-14409S
Institutional support: RVO:61388963 ; RVO:61388980
Keywords : ⋯π * hydrogen bond * dispersion
OECD category: Physical chemistry; Inorganic and nuclear chemistry (UACH-T)
Impact factor: 3.3, year: 2022
Method of publishing: Open access
https://doi.org/10.1039/D2CP04673C
Permanent Link: https://hdl.handle.net/11104/0338302File Download Size Commentary Version Access 10.1039D2CP04673C.pdf 2 2 MB Publisher’s postprint open-access - 7.0564527 - ÚOCHB 2024 RIV GB eng J - Journal Article
Lin, Jingjing - Selicharová, Irena - Mitrová, Katarína - Fabre, Benjamin - Miriyala, Vijay Madhav - Lepšík, Martin - Jiráček, Jiří - Garre Hernández, María Soledad
Targeting the insulin receptor with hormone and peptide dimers.
Journal of Peptide Science. Roč. 29, č. 4 (2023), č. článku e3461. ISSN 1075-2617. E-ISSN 1099-1387
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : insulin * dimer * bioconjugate * agonism * antagonism * peptidomimetics * receptor * peptide hormone
OECD category: Biochemistry and molecular biology
Impact factor: 2.1, year: 2022
Method of publishing: Limited access
https://doi.org/10.1002/psc.3461
Permanent Link: https://hdl.handle.net/11104/0336187 - 8.0556783 - ÚOCHB 2023 RIV US eng J - Journal Article
Giacobelli, V. G. - Fujishima, K. - Lepšík, Martin - Tretyachenko, V. - Kadavá, T. - Makarov, M. - Bednárová, Lucie - Novák, Petr - Hlouchová, Klára
In Vitro Evolution Reveals Noncationic Protein-RNA Interaction Mediated by Metal Ions.
Molecular Biology and Evolution. Roč. 39, č. 3 (2022), č. článku msac032. ISSN 0737-4038. E-ISSN 1537-1719
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) ED1.1.00/02.0109
EU Projects: European Commission(XE) 823839 - EPIC-XS
Research Infrastructure: e-INFRA CZ - 90140
Institutional support: RVO:61388963 ; RVO:61388971
Keywords : RNA-protein interaction * genetic code evolution * protein evolution * mRNA-display
OECD category: Biochemistry and molecular biology
Impact factor: 10.7, year: 2022
Method of publishing: Open access
https://doi.org/10.1093/molbev/msac032
Permanent Link: http://hdl.handle.net/11104/0330979File Download Size Commentary Version Access 0556783.pdf 5 982.6 KB Publisher’s postprint open-access
Research data: Mendeley Data - 9.0556399 - ÚOCHB 2023 RIV DE eng J - Journal Article
Tobola, F. - Lepšík, Martin - Zia, S. R. - Leffler, H. - Nilsson, U. J. - Blixt, O. - Imberty, A. - Wiltschi, B.
Engineering the Ligand Specificity of the Human Galectin-1 by Incorporation of Tryptophan Analogues.
Chembiochem. Roč. 23, č. 5 (2022), č. článku e202100593. ISSN 1439-4227. E-ISSN 1439-7633
Institutional support: RVO:61388963
Keywords : lectins * molecular dynamic * non-canonical amino acids * protein engineering * synthetic glycobiolog
OECD category: Biochemistry and molecular biology
Impact factor: 3.2, year: 2022
Method of publishing: Limited access
https://doi.org/10.1002/cbic.202100593
Permanent Link: http://hdl.handle.net/11104/0331096 - 10.0553871 - ÚOCHB 2023 RIV GB eng J - Journal Article
Benýšek, Jakub - Buša, Michal - Rubešová, Petra - Fanfrlík, Jindřich - Lepšík, Martin - Brynda, Jiří - Matoušková, Zuzana - Bartz, U. - Horn, Martin - Gütschow, M. - Mareš, Michael
Highly potent inhibitors of cathepsin K with a differently positioned cyanohydrazide warhead: structural analysis of binding mode to mature and zymogen-like enzymes.
Journal of Enzyme Inhibition and Medicinal Chemistry. Roč. 37, č. 1 (2022), s. 515-526. ISSN 1475-6366. E-ISSN 1475-6374
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : Cathepsin K * protease inhibitor * cyanohydrazide warhead * azadipeptide nitrile * crystal structure
OECD category: Biochemistry and molecular biology
Impact factor: 5.6, year: 2022
Method of publishing: Open access
https://doi.org/10.1080/14756366.2021.2024527
Permanent Link: http://hdl.handle.net/11104/0328551