Search results
- 1.0576214 - ÚOCHB 2024 RIV US eng J - Journal Article
Lemberg, K. M. - Ali, E. S. - Krečmerová, Marcela - Aguilar, J. M. H. - Alt, J. - Peters, D. E. - Zhao, L. - Wu, Y. - Nuha, N. - Asara, J. M. - Staedtke, V. - Pratilas, C. A. - Majer, Pavel - Rais, R. - Ben-Sahra, I. - Slusher, B. S.
Pro-905, a Novel Purine Antimetabolite, Combines with Glutamine Amidotransferase Inhibition to Suppress Growth of Malignant Peripheral Nerve Sheath Tumor.
Molecular Cancer Therapeutics. Roč. 22, č. 12 (2023), s. 1390-1403. ISSN 1535-7163. E-ISSN 1538-8514
R&D Projects: GA MŠMT(CZ) LM2023053
Institutional support: RVO:61388963
Keywords : loading 6-mercaptopurine therapies * standard dose 6-mercaptopurine * combination 6-mercaptopurine
OECD category: Medicinal chemistry
Impact factor: 5.7, year: 2022
Method of publishing: Open access
https://doi.org/10.1158/1535-7163.MCT-23-0258
Permanent Link: https://hdl.handle.net/11104/0345801 - 2.0558031 - ÚOCHB 2023 RIV CH eng J - Journal Article
Krečmerová, Marcela - Majer, Pavel - Rais, R. - Slusher, B. S.
Phosphonates and Phosphonate Prodrugs in Medicinal Chemistry: Past Successes and Future Prospects.
Frontiers in Chemistry. Roč. 10, May (2022), č. článku 889737. ISSN 2296-2646. E-ISSN 2296-2646
R&D Projects: GA MŠMT(CZ) LM2018133
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonates * antivirals * prodrugs * protides * GCPII * prostate-specific membrane antigen * FOLH1 * 2-PMPA
OECD category: Organic chemistry
Impact factor: 5.5, year: 2022
Method of publishing: Open access
https://doi.org/10.3389/fchem.2022.889737
Permanent Link: http://hdl.handle.net/11104/0331849 - 3.0556926 - ÚOCHB 2023 RIV CH eng J - Journal Article
Andrei, G. - Fiten, P. - Krečmerová, Marcela - Opdenakker, G. - Topalis, D. - Snoeck, R.
Poxviruses Bearing DNA Polymerase Mutations Show Complex Patterns of Cross-Resistance.
Biomedicines. Roč. 10, č. 3 (2022), č. článku 580. E-ISSN 2227-9059
R&D Projects: GA MŠMT(CZ) LM2018133
Institutional support: RVO:61388963
Keywords : vaccinia virus * DNA polymerase * drug resistance * nucleotide analogues * cidofovir * acyclic nucleoside phosphonates * phosphonoacetic acid
OECD category: Biochemistry and molecular biology
Impact factor: 4.7, year: 2022
Method of publishing: Open access
https://doi.org/10.3390/biomedicines10030580
Permanent Link: http://hdl.handle.net/11104/0331038 - 4.0555574 - ÚOCHB 2023 RIV CZ cze J - Journal Article
Krečmerová, Marcela
Od 5-azapyrimidinové chemie k thiadiazolům.
[From 5-Azapyrimidine Chemistry to Thiadiazoles.]
Chemické listy. Roč. 116, č. 3 (2022), s. 152-162. ISSN 0009-2770. E-ISSN 1213-7103
R&D Projects: GA MŠMT(CZ) LM2018133
Institutional support: RVO:61388963
Keywords : 5-azacytidine * acyclic nucleoside phosphonate * thiadiazoles * antivirotika * thiadiazoly * katepsin K * kinasa glykogensyntasy 3β * cystein-dependentní enzymy
OECD category: Organic chemistry
Impact factor: 0.6, year: 2022
Method of publishing: Open access
https://doi.org/10.54779/chl20220152
Permanent Link: http://hdl.handle.net/11104/0330035 - 5.0540528 - ÚOCHB 2022 RIV US eng J - Journal Article
Onwubiko, N. O. - Diaz, S. A. - Krečmerová, Marcela - Nasheuer, H. P.
Alkoxyalkyl Esters of Nucleotide Analogs Inhibit Polyomavirus DNA Replication and Large T Antigen Activities.
Antimicrobial Agents and Chemotherapy. Roč. 65, č. 3 (2021), č. článku e01641-20. ISSN 0066-4804. E-ISSN 1098-6596
R&D Projects: GA MŠMT(CZ) LM2018133
Institutional support: RVO:61388963
Keywords : ATPase * DNA helicase * DNA replication * Large T antigen * Nucleoside Analogs * Polyomavirus * Protein-DNA interactions
OECD category: Biochemistry and molecular biology
Impact factor: 5.938, year: 2021
Method of publishing: Limited access
https://doi.org/10.1128/aac.01641-20
Permanent Link: http://hdl.handle.net/11104/0318157 - 6.0539494 - ÚOCHB 2022 RIV CH eng J - Journal Article
Snášel, Jan - Machová, Iva - Šolínová, Veronika - Kašička, Václav - Krečmerová, Marcela - Pichová, Iva
Phosphofructokinases a and b from mycobacterium tuberculosis display different catalytic properties and allosteric regulation.
International Journal of Molecular Sciences. Roč. 22, č. 3 (2021), č. článku 1483. E-ISSN 1422-0067
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : Mycobacterium tuberculosis * glycolysis * phosphofructokinase A and B * allosteric regulation * enzyme kinetics
OECD category: Biochemistry and molecular biology
Impact factor: 6.208, year: 2021
Method of publishing: Open access
https://doi.org/10.3390/ijms22031483
Permanent Link: http://hdl.handle.net/11104/0317591 - 7.0538783 - ÚOCHB 2022 RIV GB eng J - Journal Article
Pomeislová, Alice - Otmar, Miroslav - Rubešová, Petra - Benýšek, Jakub - Matoušová, Marika - Mertlíková-Kaiserová, Helena - Pohl, Radek - Poštová Slavětínská, Lenka - Pomeisl, Karel - Krečmerová, Marcela
1,2,4-Thiadiazole acyclic nucleoside phosphonates as inhibitors of cysteine dependent enzymes cathepsin K and GSK-3β.
Bioorganic & Medicinal Chemistry. Roč. 32, Feb 15 (2021), č. článku 115998. ISSN 0968-0896. E-ISSN 1464-3391
R&D Projects: GA MŠMT(CZ) LM2018133; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963 ; RVO:61389013 ; RVO:68378271
Keywords : thiadiazoles * 5-amino-1,2,4-thiadiazol-3-(2H)-one * acyclic nucleoside phosphonates * epigenetic * cathepsin K * glycogen synthase kinase 3β
OECD category: Biochemistry and molecular biology; Polymer science (UMCH-V); Organic chemistry (FZU-D)
Impact factor: 3.461, year: 2021
Method of publishing: Limited access
https://doi.org/10.1016/j.bmc.2021.115998
Permanent Link: http://hdl.handle.net/11104/0316958 - 8.0531220 - ÚEB 2021 RIV GB eng J - Journal Article
Nowicka, Anna - Tokarz, Barbara - Zwyrtková, Jana - Tomaštíková, Eva - Procházková, Klára - Ercan, U. - Finke, A. - Rozhon, W. - Poppenberger, B. - Otmar, M. - Niezgodzki, I. - Krečmerová, Marcela - Schubert, I. - Pečinka, Aleš
Comparative analysis of epigenetic inhibitors reveals different degrees of interference with transcriptional gene silencing and induction of DNA damage.
Plant Journal. Roč. 102, č. 1 (2020), s. 68-84. ISSN 0960-7412. E-ISSN 1365-313X
R&D Projects: GA MŠMT(CZ) EF16_019/0000827; GA MŠMT(CZ) LTC18026; GA ČR(CZ) GA19-13848S
Grant - others:AVČR(CZ) Purkyně Fellowship
Institutional support: RVO:61389030 ; RVO:61388963
Keywords : Arabidopsis thaliana * cytidine analog * DNA damage * DNA methylation * epigenetic inhibitors * genome stability * Vicia faba
OECD category: Biochemistry and molecular biology
Impact factor: 6.486, year: 2020
Method of publishing: Open access
http://doi.org/10.1111/tpj.14612
Permanent Link: http://hdl.handle.net/11104/0309933File Download Size Commentary Version Access 2020_Nowicka_Plant Journal_68.pdf 6 6.1 MB Other open-access - 9.0509814 - ÚOCHB 2020 RIV GB eng J - Journal Article
Pomeisl, Karel - Krečmerová, Marcela - Pohl, Radek - Snoeck, R. - Andrei, G.
Synthesis of fluorinated acyclic nucleoside phosphonates with 5-azacytosine base moiety.
Tetrahedron. Roč. 75, č. 39 (2019), č. článku 130529. ISSN 0040-4020. E-ISSN 1464-5416
R&D Projects: GA MŠMT(CZ) LM2015064; GA MŠMT(CZ) LO1304
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonates * 5-azacytosine * fluorinated nucleotides * prodrugs * phosphonates
OECD category: Organic chemistry
Impact factor: 2.233, year: 2019
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0040402019308622?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0300433 - 10.0508547 - ÚOCHB 2020 RIV RO eng J - Journal Article
Baránek, M. - Otmar, M. - Krečmerová, Marcela - Eichmeier, A. - Moudrá, J. - Mynarzová, Z.
Effect of Different DNA Demethylating Agents on In vitro Cultures of Peach Rootstock GF 677.
Notulae Botanicae Horti Agrobotanici Cluj-Napoca. Roč. 47, č. 3 (2019), s. 896-902. ISSN 0255-965X. E-ISSN 1842-4309
Institutional support: RVO:61388963
Keywords : 5,6-dihydro-5-azacytosine * dihydroxypropyladenine * epigenetic changes * micropropagation * somaclonal variability
OECD category: Organic chemistry
Impact factor: 1.168, year: 2019
Method of publishing: Open access
https://www.notulaebotanicae.ro/index.php/nbha/article/view/11373
Permanent Link: http://hdl.handle.net/11104/0299420