Search results
- 1.0583976 - ÚOCHB 2025 RIV US eng J - Journal Article
Sedlák, František - Kvasnička, A. - Marešová, Barbora - Brumarová, R. - Dobešová, D. - Dostálová, K. - Šrámková, Karolína - Pehr, Martin - Šácha, Pavel - Friedecký, D. - Konvalinka, Jan
Parallel Metabolomics and Lipidomics of a PSMA/GCPII Deficient Mouse Model Reveal Alteration of NAAG Levels and Brain Lipid Composition.
ACS Chemical Neuroscience. Roč. 15, č. 7 (2024), s. 1342-1355. ISSN 1948-7193. E-ISSN 1948-7193
R&D Projects: GA ČR(CZ) GA21-04166S; GA MŠMT LX22NPO5102
Institutional support: RVO:61388963
Keywords : lipidomics * metabolomics * N-acetyl-aspartyl-glutamate * glutamatecarboxypeptidase II * folh1 * folyl-poly-gamma-glutamylhydrolase I
Impact factor: 5, year: 2022
Method of publishing: Open access
https://doi.org/10.1021/acschemneuro.3c00494
Permanent Link: https://hdl.handle.net/11104/0351973File Download Size Commentary Version Access 10.1021acschemneuro.3c00494.pdf 0 4.6 MB Publisher’s postprint open-access - 2.0565334 - ÚOCHB 2023 RIV NL eng J - Journal Article
Majerová, Taťána - Konvalinka, Jan
Viral proteases as therapeutic targets.
Molecular Aspects of Medicine. Roč. 88, December (2022), č. článku 101159. ISSN 0098-2997. E-ISSN 1872-9452
R&D Projects: GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Keywords : hepatitis C virus * human immunodeficiency virus * orally bioavailable inhibitor
OECD category: Virology
Impact factor: 10.6, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.mam.2022.101159
Permanent Link: https://hdl.handle.net/11104/0336883File Download Size Commentary Version Access 10.1016j.mam.2022.101159.pdf 4 8.1 MB Publisher’s postprint open-access - 3.0563164 - ÚOCHB 2023 RIV NL eng J - Journal Article
Radilová, Kateřina - Zima, Václav - Král, Michal - Machara, Aleš - Majer, Pavel - Hodek, Jan - Weber, Jan - Brynda, Jiří - Strmeň, Timotej - Konvalinka, Jan - Kožíšek, Milan
Thermodynamic and structural characterization of an optimized peptide-based inhibitor of the influenza polymerase PA-PB1 subunit interaction.
Antiviral Research. Roč. 208, December (2022), č. článku 105449. ISSN 0166-3542. E-ISSN 1872-9096
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Keywords : antiviral peptides * influenza A polymerase * protein-protein interaction * AlphaScreen * isothermal titration calorimetry
OECD category: Biochemistry and molecular biology
Impact factor: 7.6, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.antiviral.2022.105449
Permanent Link: https://hdl.handle.net/11104/0335206File Download Size Commentary Version Access 10.1016j.antiviral.2022.105449.pdf 5 6.4 MB Publisher’s postprint open-access - 4.0561657 - ÚMG 2023 RIV DE eng J - Journal Article
Grinceviciene, S. - Vaitkiene, D. - Kanopiene, D. - Vanseviciute, R. - Tykvart, J. - Sukovas, A. - Celiesiute, J. - Didziokiene, E. I. - Cizauskas, A. - Laurinaviciene, A. - Král, Vlastimil - Hlavačková, Anna - Zemanová, J. - Stravinskiene, D. - Sliziene, A. - Petrosiute, A. - Petrauskas, V. - Balsyte, R. - Grincevicius, J. - Navrátil, V. - Jahn, Ullrich - Konvalinka, Jan - Zvirbliene, A. - Matulis, D. - Matuliene, J.
Factors, associated with elevated concentration of soluble carbonic anhydrase IX in plasma of women with cervical dysplasia.
Scientific Reports. Roč. 12, č. 1 (2022), č. článku 15397. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA ČR(CZ) GA17-14510S
Institutional support: RVO:68378050 ; RVO:61388963
Keywords : squamous cell carcinoma * false negative rate * chlamydia trachomatis * natural history * cancer * risk * neoplasia * expression * osteopontin * progression
OECD category: Biochemistry and molecular biology; Biochemistry and molecular biology (UOCHB-X)
Impact factor: 4.6, year: 2022
Method of publishing: Open access
https://www.nature.com/articles/s41598-022-19492-y#Sec10
Permanent Link: https://hdl.handle.net/11104/0338631 - 5.0552067 - ÚOCHB 2023 RIV US eng J - Journal Article
Bím, Daniel - Navrátil, Michal - Gutten, Ondrej - Konvalinka, Jan - Kutil, Zsofia - Culka, Martin - Navrátil, Václav - Alexandrova, A. N. - Bařinka, Cyril - Rulíšek, Lubomír
Predicting Effects of Site-Directed Mutagenesis on Enzyme Kinetics by QM/MM and QM Calculations: A Case of Glutamate Carboxypeptidase II.
Journal of Physical Chemistry B. Roč. 126, č. 1 (2022), s. 132-143. ISSN 1520-6106. E-ISSN 1520-5207
R&D Projects: GA MŠMT(CZ) LTAUSA19148; GA ČR(CZ) GA18-14167S; GA ČR(CZ) GJ19-22269Y
Institutional support: RVO:61388963 ; RVO:86652036
Keywords : monoamine-oxidase B * reaction mechanism * membrane antigen
OECD category: Physical chemistry
Impact factor: 3.3, year: 2022
Method of publishing: Limited access
https://doi.org/10.1021/acs.jpcb.1c09240
Permanent Link: http://hdl.handle.net/11104/0327224 - 6.0547609 - ÚOCHB 2022 RIV US eng J - Journal Article
Blažková, Kristýna - Beranová, Jana - Hradilek, Martin - Kostka, Libor - Šubr, Vladimír - Etrych, Tomáš - Šácha, Pavel - Konvalinka, Jan
The Development of a High-Affinity Conformation-Sensitive Antibody Mimetic Using a Biocompatible Copolymer Carrier (iBody).
Journal of Biological Chemistry. Roč. 297, č. 5 (2021), č. článku 101342. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA ČR(CZ) GA21-04166S; GA ČR(CZ) GA19-05649S; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963 ; RVO:61389013
Keywords : antibody mimetics * bicyclic phage display * molecular recognition * HPMA copolymer * PSMA * phage display * cyclic peptide * protein targeting * nanotechnology * chemical biology
OECD category: Biochemistry and molecular biology; Polymer science (UMCH-V)
Impact factor: 5.485, year: 2021
Method of publishing: Open access
https://doi.org/10.1016/j.jbc.2021.101342
Permanent Link: http://hdl.handle.net/11104/0323818 - 7.0547173 - ÚMCH 2022 RIV GB eng J - Journal Article
Šubr, Vladimír - Ormsby, Tereza - Šácha, Pavel - Konvalinka, Jan - Etrych, Tomáš - Kostka, Libor
The role of the biotin linker in polymer antibody mimetics, iBodies, in biochemical assays.
Polymer Chemistry. Roč. 12, č. 41 (2021), s. 6009-6021. ISSN 1759-9954. E-ISSN 1759-9962
R&D Projects: GA ČR(CZ) GA19-05649S; GA ČR(CZ) GA19-10280S; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61389013 ; RVO:61388963
Keywords : HPMA * iBody * biotin
OECD category: Polymer science; Biochemical research methods (UOCHB-X)
Impact factor: 5.364, year: 2021
Method of publishing: Limited access
https://pubs.rsc.org/en/content/articlelanding/2021/PY/D1PY00707F
Permanent Link: http://hdl.handle.net/11104/0324045 - 8.0544791 - ÚOCHB 2022 RIV FR eng J - Journal Article
Šimková, Adéla - Ormsby, Tereza - Sidej, Natan - Poštová Slavětínská, Lenka - Brynda, Jiří - Beranová, Jana - Šácha, Pavel - Majer, Pavel - Konvalinka, Jan
Structure-activity relationship and biochemical evaluation of novel fibroblast activation protein and prolyl endopeptidase inhibitors with α-ketoamide warheads.
European Journal of Medicinal Chemistry. Roč. 224, Nov 15 (2021), č. článku 113717. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA ČR(CZ) GA19-10280S; GA MZd(CZ) NV15-31379A; GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) LM2015064
Institutional support: RVO:61388963
Keywords : fibroblast activation protein * seprase * FAP inhibitor * serine protease inhibition * prolyl endopeptidase * α-Ketoamide inhibitor
OECD category: Medicinal chemistry
Impact factor: 7.088, year: 2021
Method of publishing: Open access
https://doi.org/10.1016/j.ejmech.2021.113717
Permanent Link: http://hdl.handle.net/11104/0321598 - 9.0544040 - ÚOCHB 2022 RIV CH eng J - Journal Article
Reiberger, Róbert - Radilová, Kateřina - Král, Michal - Zima, Václav - Majer, Pavel - Brynda, Jiří - Dračínský, Martin - Konvalinka, Jan - Kožíšek, Milan - Machara, Aleš
Synthesis and In Vitro Evaluation of C-7 and C-8 Luteolin Derivatives as Influenza Endonuclease Inhibitors.
International Journal of Molecular Sciences. Roč. 22, č. 14 (2021), č. článku 7735. E-ISSN 1422-0067
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) LM2018133
Institutional support: RVO:61388963
Keywords : bio-isosterism * cross-coupling * endonuclease inhibitor * flavonoids * influenza * Mannich reaction * RNA polymerase
OECD category: Biochemistry and molecular biology
Impact factor: 6.208, year: 2021
Method of publishing: Open access
https://doi.org/10.3390/ijms22147735
Permanent Link: http://hdl.handle.net/11104/0321100 - 10.0543118 - ÚOCHB 2022 RIV US eng J - Journal Article
Kryštůfek, Robin - Šácha, Pavel - Starková, Jana - Brynda, Jiří - Hradilek, Martin - Tloušťová, Eva - Grzymska, J. - Rut, W. - Boucher, M. J. - Drag, M. - Majer, Pavel - Hájek, Miroslav - Řezáčová, Pavlína - Madhani, H. D. - Craik, C. S. - Konvalinka, Jan
Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery.
Journal of Medicinal Chemistry. Roč. 64, č. 10 (2021), s. 6706-6719. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : immunodeficiency virus HIV * in-vitro * virulence factors
OECD category: Medicinal chemistry
Impact factor: 8.039, year: 2021
Method of publishing: Open access
https://doi.org/10.1021/acs.jmedchem.0c02177
Permanent Link: http://hdl.handle.net/11104/0320402