Search results

  1. 1.
    0577921 - ÚOCHB 2024 RIV GB eng J - Journal Article
    Kraina, Pavel - Česnek, Michal - Tloušťová, Eva - Mertlíková-Kaiserová, Helena - Fulton, C. J. - Davidson, E. K. - Smith, B. P. - Watts, V. J. - Janeba, Zlatko
    Discovery of a potent and selective human AC2 inhibitor based on 7-deazapurine analogues of adefovir.
    Bioorganic & Medicinal Chemistry. Roč. 95, November (2023), č. článku 117508. ISSN 0968-0896. E-ISSN 1464-3391
    R&D Projects: GA MŠMT LTAUSA18086
    Institutional support: RVO:61388963
    Keywords : acyclic nucleoside phosphonates * adefovir * 7-deazapurine * prodrugs * adenylate cyclase
    OECD category: Organic chemistry
    Impact factor: 3.5, year: 2022
    Method of publishing: Limited access
    https://doi.org/10.1016/j.bmc.2023.117508
    Permanent Link: https://hdl.handle.net/11104/0346999
     
     
  2. 2.
    0575380 - ÚOCHB 2024 RIV NL eng J - Journal Article
    Spengler, J. R. - Carter, K. - Delang, L. - Durantel, D. - Gowen, B. B. - Herrero, L. J. - Hurst, B. - Janeba, Zlatko - Jordan, R. - Luo, D. - Meier, C. - Moffat, J. - Rocha-Pereira, J. - Seley-Radtke, K. L. - Welch, S. R. - Schang, L. M.
    Meeting report: 36th International Conference on Antiviral Research in Lyon, France March 13-17, 2023.
    Antiviral Research. Roč. 217, September (2023), č. článku 105678. ISSN 0166-3542. E-ISSN 1872-9096
    Institutional support: RVO:61388963
    Keywords : viruses * antivirals * inhibitors
    OECD category: Virology
    Impact factor: 7.6, year: 2022
    Method of publishing: Limited access
    https://doi.org/10.1016/j.antiviral.2023.105678
    Permanent Link: https://hdl.handle.net/11104/0345183
     
     
  3. 3.
    0573369 - ÚOCHB 2024 RIV US eng J - Journal Article
    Vaňková, Karolína - Keough, D. T. - Hocková, Dana - Guddat, L. W. - Janeba, Zlatko
    N2'-Branched Acyclic Nucleoside Phosphonates Containing 9-Deazahypoxanthine as Inhibitors of Plasmodium falciparum 6-Oxopurine Phosphoribosyltransferase.
    ChemMedChem. Roč. 18, č. 15 (2023), č. článku e202300211. ISSN 1860-7179. E-ISSN 1860-7187
    R&D Projects: GA ČR(CZ) GA19-07707S
    Institutional support: RVO:61388963
    Keywords : acyclic nucleoside phosphonates * inhibitors * hypoxanthine-guanine-(xanthine) phosphoribosyltransferase * malaria * Plasmodium falciparum
    OECD category: Organic chemistry
    Impact factor: 3.4, year: 2022
    Method of publishing: Open access
    https://doi.org/10.1002/cmdc.202300211
    Permanent Link: https://hdl.handle.net/11104/0343833
     
     
  4. 4.
    0572565 - ÚOCHB 2024 RIV US eng J - Journal Article
    Skácel, Jan - Djukic, Stefan - Baszczyňski, Ondřej - Kalčic, Filip - Bílek, Tadeáš - Chalupský, Karel - Kozák, Jaroslav - Dvořáková, Alexandra - Tloušťová, Eva - Kráľová, Zuzana - Šmídková, Markéta - Voldřich, Jan - Rumlová, M. - Pachl, Petr - Brynda, Jiří - Vučková, Tereza - Fábry, Milan - Snášel, Jan - Pichová, Iva - Řezáčová, Pavlína - Mertlíková-Kaiserová, Helena - Janeba, Zlatko
    Design, Synthesis, Biological Evaluation, and Crystallographic Study of Novel Purine Nucleoside Phosphorylase Inhibitors.
    Journal of Medicinal Chemistry. Roč. 66, č. 10 (2023), s. 6652-6681. ISSN 0022-2623. E-ISSN 1520-4804
    R&D Projects: GA TA ČR(CZ) TN01000013; GA MŠMT(CZ) EF16_019/0000729; GA MŠMT LX22NPO5102
    Institutional support: RVO:61388963
    Keywords : multisubstrate analog inhibitors * transition-state analog * human erythrocytes
    OECD category: Organic chemistry
    Impact factor: 7.3, year: 2022
    Method of publishing: Open access
    https://doi.org/10.1021/acs.jmedchem.2c02097
    Permanent Link: https://hdl.handle.net/11104/0343213
    FileDownloadSizeCommentaryVersionAccess
    10.1021acs.jmedchem.2c02097.pdf15.7 MBPublisher’s postprintopen-access
     
     
  5. 5.
    0568174 - ÚOCHB 2024 RIV US eng J - Journal Article
    Prener, Ladislav - Baszczyňski, Ondřej - Kaiser, Martin Maxmilian - Dračínský, Martin - Stepan, G. - Lee, Y. J. - Brumshtein, B. - Yu, H. - Jansa, P. - Lansdon, E. B. - Janeba, Zlatko
    Design and Synthesis of Novel HIV-1 NNRTIs with Bicyclic Cores and with Improved Physicochemical Properties.
    Journal of Medicinal Chemistry. Roč. 66, č. 3 (2023), s. 1761-1777. ISSN 0022-2623. E-ISSN 1520-4804
    Institutional support: RVO:61388963
    Keywords : reverse transcriptase inhibitors * wild type * optimization
    OECD category: Organic chemistry
    Impact factor: 7.3, year: 2022
    Method of publishing: Open access
    https://doi.org/10.1021/acs.jmedchem.2c01574
    Permanent Link: https://hdl.handle.net/11104/0339509
     
     
  6. 6.
    0559133 - ÚOCHB 2023 RIV FR eng J - Journal Article
    Vaňková, Karolína - Doleželová, Eva - Tloušťová, Eva - Hocková, Dana - Zíková, Alena - Janeba, Zlatko
    Synthesis and anti-trypanosomal evaluation of novel N-branched acyclic nucleoside phosphonates bearing 7-aryl-7-deazapurine nucleobase.
    European Journal of Medicinal Chemistry. Roč. 239, September (2022), č. článku 114559. ISSN 0223-5234. E-ISSN 1768-3254
    R&D Projects: GA ČR(CZ) GA19-07707S; GA MŠMT(CZ) EF16_019/0000759
    Institutional support: RVO:61388963 ; RVO:60077344
    Keywords : acyclic nucleoside phosphonates * nucleotides * Suzuki reaction * Trypanosoma * tubercidin
    OECD category: Organic chemistry
    Impact factor: 6.7, year: 2022
    Method of publishing: Limited access
    https://doi.org/10.1016/j.ejmech.2022.114559
    Permanent Link: https://hdl.handle.net/11104/0332552
     
     
  7. 7.
    0557633 - ÚOCHB 2023 RIV GB eng J - Journal Article
    Janeba, Zlatko - Elizondo, C.
    Genus Mammillaria Haw. in the Yucatan Peninsula.
    Bradleya. Roč. 40, May (2022), s. 150-160. ISSN 0265-086X
    Institutional support: RVO:61388963
    Keywords : Yucatan Peninsula * cactaceae * Mammillaria columbiana subsp. yucatanensis * Mammillaria heyderi subsp. gaumeri * gaumeri * distribution range * conservation
    OECD category: Plant sciences, botany
    Impact factor: 1.6, year: 2022
    Method of publishing: Limited access
    https://doi.org/10.25223/brad.sp40.2022.a14
    Permanent Link: http://hdl.handle.net/11104/0331638
     
     
  8. 8.
    0556761 - ÚOCHB 2023 RIV US eng J - Journal Article
    Klejch, Tomáš - Keough, D. T. - King, G. - Doleželová, Eva - Česnek, Michal - Buděšínský, Miloš - Zíková, Alena - Janeba, Zlatko - Guddat, L. W. - Hocková, Dana
    Stereo-Defined Acyclic Nucleoside Phosphonates are Selective and Potent Inhibitors of Parasite 6-Oxopurine Phosphoribosyltransferases.
    Journal of Medicinal Chemistry. Roč. 65, č. 5 (2022), s. 4030-4057. ISSN 0022-2623. E-ISSN 1520-4804
    R&D Projects: GA ČR(CZ) GA19-07707S; GA MŠMT(CZ) EF16_019/0000759
    Institutional support: RVO:61388963 ; RVO:60077344
    Keywords : hypoxanthine-guanine phosporibosyltransferase * Plasmodium falciparum * Helicobacter pylori
    OECD category: Medicinal chemistry
    Impact factor: 7.3, year: 2022
    Method of publishing: Limited access
    https://doi.org/10.1021/acs.jmedchem.1c01881
    Permanent Link: http://hdl.handle.net/11104/0330950
     

    Research data: PDB, PDB, PDB
     
  9. 9.
    0553286 - ÚOCHB 2023 RIV US eng J - Journal Article
    Khatun, M. - Kumar, K. - Baidya, A. - Mondal, R. K. - Baszczyňski, Ondřej - Kalčic, Filip - Banerjee, S. - Dhali, G. K. - Das, K. - Chowdhury, A. - Janeba, Zlatko - Chakrabarti, S. - Datta, S.
    Variability in the Responses of Hepatitis B Virus D-Subgenotypes to Antiviral Therapy: Designing Pan-D-Subgenotypic Reverse Transcriptase Inhibitors.
    Journal of Virology. Roč. 96, č. 2 (2022), č. článku e01800-21. ISSN 0022-538X. E-ISSN 1098-5514
    Institutional support: RVO:61388963
    Keywords : antiviral activity * entecavir * hepatitis B virus D-subgenotypes * high throughput virtual screening * phosphonate prodrug * zenofovir
    OECD category: Organic chemistry
    Impact factor: 5.4, year: 2022
    Method of publishing: Limited access
    https://doi.org/10.1128/JVI.01800-21
    Permanent Link: http://hdl.handle.net/11104/0328267
     
     
  10. 10.
    0552051 - ÚOCHB 2023 RIV GB eng J - Journal Article
    Procházková, Eliška - Filo, J. - Mužíková Čechová, Lucie - Dračínský, Martin - Císařová, I. - Janeba, Zlatko - Kawamura, I. - Naito, A. - Kuběna, Ivo - Nádaždy, P. - Šiffalovič, P. - Cigáň, M.
    Photoswitching of 5-phenylazopyrimidines in crystalline powders and thin films.
    Dyes and Pigments. Roč. 199, March (2022), č. článku 110066. ISSN 0143-7208. E-ISSN 1873-3743
    R&D Projects: GA ČR(CZ) GA20-01472S
    Institutional support: RVO:61388963 ; RVO:68081723
    Keywords : Azo dyes * NMR spectroscopy * solid-state photoswitching * thin films
    OECD category: Analytical chemistry; Analytical chemistry (UFM-A)
    Impact factor: 4.5, year: 2022
    Method of publishing: Limited access
    https://doi.org/10.1016/j.dyepig.2021.110066
    Permanent Link: http://hdl.handle.net/11104/0327213
     

    Research data: CCDC, CCDC, CCDC, CCDC, CCDC
     

  This site uses cookies to make them easier to browse. Learn more about how we use cookies.