Search results

  1. 1.
    0541879 - ÚOCHB 2022 RIV US eng J - Journal Article
    Perlíková, Pavla - Krajczyk, Anna - Doleželová, Eva - Slapničková, Martina - Milisavljevič, Nemanja - Poštová Slavětínská, Lenka - Tloušťová, Eva - Gurská, S. - Džubák, P. - Hajdúch, M. - Zíková, Alena - Hocek, Michal
    Synthesis and Antitrypanosomal Activity of 6-Substituted 7-Methyl-7-deazapurine Nucleosides.
    ACS Infectious Diseases. Roč. 7, č. 4 (2021), s. 917-926. ISSN 2373-8227
    R&D Projects: GA MŠk(CZ) EF16_019/0000729; GA MŠk(CZ) EF16_019/0000759; GA ČR(CZ) GA19-08124S; GA ČR(CZ) GA19-07707S; GA MŠk(CZ) LM2015064
    Grant - others:AV ČR(CZ) AP1501
    Program:Akademická prémie - Praemium Academiae
    Institutional support: RVO:61388963 ; RVO:60077344
    Keywords : nucleosides * antiparasitic activity * antitrypanosomal * cytotoxicity
    OBOR OECD: Organic chemistry
    Impact factor: 4.614, year: 2019
    https://doi.org/10.1021/acsinfecdis.1c00062
    Permanent Link: http://hdl.handle.net/11104/0319376
     
  2. 2.
    0541749 - ÚOCHB 2022 RIV US eng J - Journal Article
    Magriñá, I. - Ortiz, M. - Simonova, Anna - Hocek, Michal - O´Sullivan, C. K. - Forster, R. J.
    Ferrocene-Containing DNA Monolayers: Influence of Electrostatics on the Electron Transfer Dynamics.
    Langmuir. Roč. 37, č. 11 (2021), s. 3359-3369. ISSN 0743-7463
    R&D Projects: GA MŠk(CZ) EF16_019/0000729
    Grant - others:AV ČR(CZ) AP1501
    Program:Akademická prémie - Praemium Academiae
    Institutional support: RVO:61388963
    OBOR OECD: Organic chemistry
    Impact factor: 3.557, year: 2019
    https://doi.org/10.1021/acs.langmuir.0c03485
    Permanent Link: http://hdl.handle.net/11104/0319281
     
  3. 3.
    0541740 - ÚOCHB 2022 RIV DE eng J - Journal Article
    Güixens-Gallardo, Pedro - Hocek, Michal
    Acetophenyl‐thienyl‐aniline‐Linked Nucleotide for Construction of Solvatochromic Fluorescence Light‐Up DNA Probes Sensing Protein‐DNA Interactions.
    Chemistry - A European Journal. Roč. 27 (2021). ISSN 0947-6539
    R&D Projects: GA ČR(CZ) GA17-14791S; GA MŠk(CZ) EF16_019/0000729
    Grant - others:AV ČR(CZ) AP1501
    Program:Akademická prémie - Praemium Academiae
    Institutional support: RVO:61388963
    Keywords : fluorescent labelling * DNA polymerases * nucleotides * protein-DNA interactions * solvatochromism
    OBOR OECD: Organic chemistry
    Impact factor: 4.857, year: 2019
    https://doi.org/10.1002/chem.202100575
    Permanent Link: http://hdl.handle.net/11104/0319263
     
  4. 4.
    0541603 - ÚOCHB 2022 RIV GB eng J - Journal Article
    Nguyen, Van hai - Tichý, Michal - Rožánková, Samanta - Pohl, Radek - Downey, Alan Michael - Doleželová, Eva - Tloušťová, Eva - Slapničková, Martina - Zíková, Alena - Hocek, Michal
    Synthesis and anti-trypanosomal activity of 3′-fluororibonucleosides derived from 7-deazapurine nucleosides.
    Bioorganic and Medicinal Chemistry Letters. Roč. 40, May 15 (2021), č. článku 127957. ISSN 0960-894X
    R&D Projects: GA ČR(CZ) GA19-08124S; GA ČR(CZ) GA19-07707S
    Grant - others:AV ČR(CZ) AP1501
    Program:Akademická prémie - Praemium Academiae
    Institutional support: RVO:61388963 ; RVO:60077344
    Keywords : nucleosides * deazapurines * fluorinated compounds * antiparasitic * anti-trypanosomal agents
    OBOR OECD: Organic chemistry; Organic chemistry (BC-A)
    Impact factor: 2.572, year: 2019
    https://doi.org/10.1016/j.bmcl.2021.127957
    Permanent Link: http://hdl.handle.net/11104/0319136
     
  5. 5.
    0541460 - ÚOCHB 2022 RIV US eng J - Journal Article
    Milisavljevič, Nemanja - Konkoľová, Eva - Kozák, Jaroslav - Hodek, Jan - Veselovská, Lucia - Sýkorová, Veronika - Čížek, Karel - Pohl, Radek - Eyer, Luděk - Svoboda, P. - Růžek, Daniel - Weber, Jan - Nencka, Radim - Bouřa, Evžen - Hocek, Michal
    Antiviral Activity of 7-Substituted 7-Deazapurine Ribonucleosides, Monophosphate Prodrugs, and Triphoshates against Emerging RNA Viruses.
    ACS Infectious Diseases. Roč. 7, č. 2 (2021), s. 471-478. ISSN 2373-8227
    R&D Projects: GA ČR(CZ) GA19-08124S; GA MZd(CZ) NU20-05-00472; GA MŠk(CZ) LTAUSA18016; GA MŠk(CZ) EF16_019/0000729
    Grant - others:AV ČR(CZ) AP1501
    Program:Akademická prémie - Praemium Academiae
    Institutional support: RVO:61388963 ; RVO:60077344
    Keywords : 7-deazapurine ribonucleosides * monophosphate prodrugs * triphoshates * RNA viruses * 7-deazapurine ribonucleosides monophosphate prodrugs triphoshates RNA viruses antiviral activity
    OBOR OECD: Organic chemistry
    Impact factor: 4.614, year: 2019
    https://doi.org/10.1021/acsinfecdis.0c00829
    Permanent Link: http://hdl.handle.net/11104/0319010
     
  6. 6.
    0537186 - ÚOCHB 2021 RIV GB eng J - Journal Article
    Ondruš, Marek - Sýkorová, Veronika - Bednárová, Lucie - Pohl, Radek - Hocek, Michal
    Enzymatic synthesis of hypermodified DNA polymers for sequence-specific display of four different hydrophobic groups.
    Nucleic Acids Research. Roč. 48, č. 21 (2020), s. 11982-11993. ISSN 1362-4962
    R&D Projects: GA ČR(CZ) GX20-00885X
    Grant - others:AV ČR(CZ) AP1501
    Program:Akademická prémie - Praemium Academiae
    Institutional support: RVO:61388963
    Keywords : nucleotides * DNA * functionalized polymers
    Subject RIV: CC - Organic Chemistry
    OBOR OECD: Organic chemistry
    Impact factor: 11.147, year: 2018
    https://doi.org/10.1093/nar/gkaa999
    Permanent Link: http://hdl.handle.net/11104/0316289
     
  7. 7.
    0535556 - ÚOCHB 2021 RIV US eng J - Journal Article
    Chakrapani, Aswathi - Vaňková Hausnerová, Viola - Ruiz-Larrabeiti, Olatz - Pohl, Radek - Krásný, Libor - Hocek, Michal
    Photocaged 5-(Hydroxymethyl)pyrimidine Nucleoside Phosphoramidites for Specific Photoactivatable Epigenetic Labeling of DNA.
    Organic Letters. Roč. 22, č. 22 (2020), s. 9081-9085. ISSN 1523-7060
    R&D Projects: GA MŠk(CZ) EF16_019/0000729; GA ČR(CZ) GX20-00885X; GA ČR(CZ) GA20-12109S
    Grant - others:AV ČR(CZ) Akademická prémie - Praemium Academiae
    Institutional support: RVO:61388963 ; RVO:61388971
    Keywords : nucleosides * epigenetic nucleobases * oligonucleotides
    Subject RIV: CC - Organic Chemistry; EE - Microbiology, Virology (MBU-M)
    OBOR OECD: Organic chemistry; Microbiology (MBU-M)
    Impact factor: 6.091, year: 2019
    https://doi.org/10.1021/acs.orglett.0c03462
    Permanent Link: http://hdl.handle.net/11104/0313624
     
  8. 8.
    0534197 - ÚOCHB 2021 RIV US eng J - Journal Article
    Veselovská, Lucia - Pohl, Radek - Tloušťová, Eva - Gurská, S. - Džubák, P. - Hajdúch, M. - Hocek, Michal
    Pyrido-Fused Deazapurine Bases: Synthesis and Glycosylation of 4-Substituted 9H-Pyrido[2′,3′:4,5]- and Pyrido[4′,3′:4,5]pyrrolo[2,3-d]pyrimidines.
    ACS Omega. Roč. 5, č. 40 (2020), s. 26278-26286. ISSN 2470-1343
    R&D Projects: GA ČR(CZ) GA19-08124S; GA MŠk(CZ) LM2015064
    Grant - others:AV ČR(CZ) AP1501
    Program:Akademická prémie - Praemium Academiae
    Institutional support: RVO:61388963
    Keywords : Thymidylate synthase inhibitors * receptor tyrosine kinase * biological activity
    Subject RIV: CC - Organic Chemistry
    OBOR OECD: Organic chemistry
    Impact factor: 2.870, year: 2019
    https://doi.org/10.1021/acsomega.0c04302
    Permanent Link: http://hdl.handle.net/11104/0312441
     
  9. 9.
    0532766 - ÚOCHB 2021 RIV DE eng J - Journal Article
    Veselovská, Lucia - Kudlová, N. - Gurská, S. - Lišková, B. - Medvedíková, M. - Hodek, Ondřej - Tloušťová, Eva - Milisavljevič, Nemanja - Tichý, Michal - Perlíková, Pavla - Mertlíková-Kaiserová, Helena - Trylčová, Jana - Pohl, Radek - Klepetářová, Blanka - Džubák, P. - Hajdúch, M. - Hocek, Michal
    Synthesis and Cytotoxic and Antiviral Activity Profiling of All-Four Isomeric Series of Pyrido-Fused 7-Deazapurine Ribonucleosides.
    Chemistry - A European Journal. Roč. 26, č. 57 (2020), s. 13002-13015. ISSN 0947-6539
    R&D Projects: GA ČR(CZ) GA19-08124S; GA MZd(CZ) NV15-31984A; GA MŠk(CZ) LM2015064
    Grant - others:AV ČR(CZ) AP1501
    Program:Akademická prémie - Praemium Academiae
    Institutional support: RVO:61388963
    Keywords : antitumor agents * antiviral agents * drug discovery * phosphorylation * ribonucleosides
    Subject RIV: CC - Organic Chemistry
    OBOR OECD: Organic chemistry
    Impact factor: 4.857, year: 2019
    https://doi.org/10.1002/chem.202001124
    Permanent Link: http://hdl.handle.net/11104/0311179
     
  10. 10.
    0532387 - ÚOCHB 2021 RIV US eng J - Journal Article
    Fleuti, Marianne - Bártová, Kateřina - Poštová Slavětínská, Lenka - Tloušťová, Eva - Tichý, Michal - Gurská, S. - Pavliš, P. - Džubák, P. - Hajdúch, M. - Hocek, Michal
    Synthesis and Biological Profiling of Pyrazolo-Fused 7-Deazapurine Nucleosides.
    Journal of Organic Chemistry. Roč. 85, č. 16 (2020), s. 10539-10551. ISSN 0022-3263
    R&D Projects: GA ČR(CZ) GA19-08124S; GA MZd(CZ) NV15-31984A; GA MŠk(CZ) LM2015064
    Grant - others:AV ČR(CZ) AP1501
    Program:Akademická prémie - Praemium Academiae
    Institutional support: RVO:61388963
    Keywords : tyrosine kinase * inhibitors * adenosine
    Subject RIV: CC - Organic Chemistry
    OBOR OECD: Organic chemistry
    Impact factor: 4.335, year: 2019
    https://doi.org/10.1021/acs.joc.0c00928
    Permanent Link: http://hdl.handle.net/11104/0310889