Search results

  1. 1.
    0636785 - ÚOCHB 2026 RIV DE eng J - Journal Article
    Kaiser, Lukáš - Ondruš, Marek - Poštová Slavětínská, Lenka - Raindlová, Veronika - Hocek, Michal
    Polymerase Synthesis of Hypermodified DNA Displaying a Combination of Thiol, Hydroxyl, Carboxylate, and Imidazole Functional Groups in the Major Groove.
    Chemistry - A European Journal. Roč. 31, č. 34 (2025), č. článku e202501034. ISSN 0947-6539. E-ISSN 1521-3765
    R&D Projects: GA ČR(CZ) GX20-00885X
    Institutional support: RVO:61388963
    Keywords : DNA * enzymatic syntheses * nucleotides * polymerases
    Impact factor: 3.9, year: 2023 ; AIS: 0.89, rok: 2023
    Method of publishing: Open access
    Result website:
    https://doi.org/10.1002/chem.202501034DOI: https://doi.org/10.1002/chem.202501034
    Permanent Link: https://hdl.handle.net/11104/0367776
     
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    10.1002chem.202501034.pdf12.2 MBPublisher’s postprintopen-access
     
    Research data: Národní repozitář
  2. 2.
    0635671 - ÚOCHB 2026 RIV US eng J - Journal Article
    Šinkevičiūtė, Ugnė - Sánchez Quirante, Tania - Rožánková, Samanta - Poštová Slavětínská, Lenka - Raindlová, Veronika - Hocek, Michal
    Synthesis of 2-Substituted Adenosine Triphosphate Derivatives and their use in Enzymatic Synthesis and Postsynthetic Labelling of RNA.
    Chembiochem. Roč. 26, č. 12 (2025), č. článku e202500241. ISSN 1439-4227. E-ISSN 1439-7633
    R&D Projects: GA MŠMT(CZ) EH22_008/0004575
    EU Projects: European Commission(XE) 861381 - NATURE-ETN
    Institutional support: RVO:61388963
    Keywords : click reactions * DNA polymerases * nucleosides triphosphates * nucleotides * polyA polymerase * RNA polymerases * thiol-ene addition
    Impact factor: 2.6, year: 2023 ; AIS: 0.736, rok: 2023
    Method of publishing: Open access
    Result website:
    https://doi.org/10.1002/cbic.202500241DOI: https://doi.org/10.1002/cbic.202500241
    Permanent Link: https://hdl.handle.net/11104/0366704
     
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    10.1002cbic.202500241.pdf01.1 MBPublisher’s postprintopen-access
     
    Research data: Národní repozitář
  3. 3.
    0618183 - ÚOCHB 2026 RIV US eng J - Journal Article
    Kuprikova, Natalia - Ondruš, Marek - Bednárová, Lucie - Kraus, Tomáš - Poštová Slavětínská, Lenka - Sýkorová, Veronika - Hocek, Michal
    Zwitterionic DNA: enzymatic synthesis of hypermodified DNA bearing four different cationic substituents at all four nucleobases.
    Nucleic Acids Research. Roč. 53, č. 5 (2025), č. článku gkaf155. ISSN 0305-1048. E-ISSN 1362-4962
    R&D Projects: GA ČR(CZ) GX20-00885X
    Institutional support: RVO:61388963
    Keywords : catalytic repertoire * primer extension * nucleic-acids
    Impact factor: 16.7, year: 2023 ; AIS: 5.863, rok: 2023
    Method of publishing: Open access
    Result website:
    https://doi.org/10.1093/nar/gkaf155DOI: https://doi.org/10.1093/nar/gkaf155
    Permanent Link: https://hdl.handle.net/11104/0365078
     
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    10.1093nargkaf155.pdf21.7 MBPublisher’s postprintopen-access
     
  4. 4.
    0604332 - ÚOCHB 2026 RIV GB eng J - Journal Article
    Šoltysová, Markéta - Güixens-Gallardo, Pedro - Sieglová, Irena - Soldánová, Anna - Krejčiříková, Veronika - Fábry, Milan - Brynda, Jiří - Khoroshyy, Petro - Hocek, Michal - Řezáčová, Pavlína
    Using environment-sensitive tetramethylated thiophene-BODIPY fluorophores in DNA probes for studying effector-induced conformational changes of protein–DNA complexes.
    RSC Chemical Biology. Roč. 6, č. 3 (2025), s. 376-386. ISSN 2633-0679. E-ISSN 2633-0679
    R&D Projects: GA MŠMT(CZ) EH22_008/0004575; GA ČR(CZ) GX20-00885X
    Institutional support: RVO:61388963
    Keywords : Bacillus subtilis * transcription * repressor
    OECD category: Biochemistry and molecular biology
    Impact factor: 4.2, year: 2023
    Method of publishing: Open access
    Result website:
    https://doi.org/10.1039/D4CB00260ADOI: https://doi.org/10.1039/D4CB00260A
    Permanent Link: https://hdl.handle.net/11104/0361714
     
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    10.1039D4CB00260A.pdf51.6 MBPublisher’s postprintopen-access
     
  5. 5.
    0603544 - ÚOCHB 2026 RIV DE eng J - Journal Article
    Šinkevičiūtė, Ugnė - Dvořáková, Marcela - Tichý, Michal - Gurská, S. - Ječmeňová, K. - Poštová Slavětínská, Lenka - Džubák, P. - Hajdúch, M. - Hocek, Michal
    Synthesis and Biological Activity of 2,6-Disubstituted 7-Deazapurine Ribonucleosides.
    European Journal of Organic Chemistry. Roč. 28, č. 5 (2025), č. článku e202401187. ISSN 1434-193X. E-ISSN 1099-0690
    R&D Projects: GA MŠMT LX22NPO5102
    Research Infrastructure: CZ-OPENSCREEN IV - 90252; EATRIS-CZ IV - 90253
    Institutional support: RVO:61388963
    Keywords : nucleosides * pyrrolo[2,3-d]pyrimidines * cytostatics * adenosine receptors * cross-coupling * glycosylation * 7-deazapurine nucleosides * cytotoxic activity
    OECD category: Organic chemistry
    Impact factor: 2.5, year: 2023 ; AIS: 0.517, rok: 2023
    Method of publishing: Open access
    Result website:
    https://doi.org/10.1002/ejoc.202401187DOI: https://doi.org/10.1002/ejoc.202401187
    Permanent Link: https://hdl.handle.net/11104/0360888
     
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    10.1002ejoc.202401187.pdf34.7 MBPublisher’s postprintopen-access
     
  6. 6.
    0603499 - ÚOCHB 2026 RIV US eng J - Journal Article
    Ivancová, Ivana - Sánchez Quirante, Tania - Ondruš, Marek - Pohl, Radek - Vlková, Marta - Žilecká, Eva - Bouřa, Evžen - Hocek, Michal
    Enzymatic synthesis of reactive RNA probes containing squaramate-linked cytidine or adenosine for bioconjugations and cross-linking with lysine-containing peptides and proteins.
    Communications Chemistry. Roč. 8, January (2025), č. článku 1. ISSN 2399-3669. E-ISSN 2399-3669
    R&D Projects: GA ČR(CZ) GX20-00885X; GA MŠMT(CZ) EH22_008/0004575
    Institutional support: RVO:61388963
    Keywords : binding sites * DNA * identification
    OECD category: Organic chemistry
    Impact factor: 5.9, year: 2023 ; AIS: 1.585, rok: 2023
    Method of publishing: Open access
    Result website:
    https://doi.org/10.1038/s42004-024-01399-6DOI: https://doi.org/10.1038/s42004-024-01399-6
    Permanent Link: https://hdl.handle.net/11104/0360822
     
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    10.1038s42004-024-01399-6.pdf42.1 MBPublisher’s postprintopen-access
     
    Research data: Národní repozitář
  7. 7.
    0600677 - ÚOCHB 2025 RIV US eng J - Journal Article
    Gracias, Filip - Pohl, Radek - Sýkorová, Veronika - Hocek, Michal
    Bacteriophage-related epigenetic natural and non-natural pyrimidine nucleotides and their influence on transcription with T7 RNA polymerase.
    Communications Chemistry. Roč. 7, November (2024), č. článku 256. ISSN 2399-3669. E-ISSN 2399-3669
    R&D Projects: GA MŠMT(CZ) EH22_008/0004575
    Institutional support: RVO:61388963
    Keywords : major groove * deoxyribonucleic acid * modified base
    OECD category: Biochemistry and molecular biology
    Impact factor: 5.9, year: 2023 ; AIS: 1.585, rok: 2023
    Method of publishing: Open access
    Result website:
    https://doi.org/10.1038/s42004-024-01354-5DOI: https://doi.org/10.1038/s42004-024-01354-5
    Permanent Link: https://hdl.handle.net/11104/0357989
     
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    s42004-024-01354-5.pdf42.5 MBPublisher’s postprintopen-access
     
  8. 8.
    0587190 - ÚOCHB 2025 RIV DE eng J - Journal Article
    Spampinato, Ambra - Leone, Denise Liu - Pohl, Radek - Tarábek, Ján - Šoltysová, Markéta - Polák, Marek - Kádek, Alan - Sýkorová, Veronika - Řezáčová, Pavlína - Hocek, Michal
    ABNOH-Linked Nucleotides and DNA for Bioconjugation and Cross-linking with Tryptophan-Containing Peptides and Proteins.
    Chemistry - A European Journal. Roč. 30, č. 49 (2024), č. článku e202402151. ISSN 0947-6539. E-ISSN 1521-3765
    R&D Projects: GA ČR(CZ) GX20-00885X; GA MŠMT(CZ) EH22_008/0004575
    Research Infrastructure: CIISB III - 90242
    Institutional support: RVO:61388963 ; RVO:61388971
    Keywords : bioconjugation * DNA * proteins * nucleotides * oligonucleotides * peptides * N-oxyl radicals
    OECD category: Biochemistry and molecular biology
    Impact factor: 3.9, year: 2023 ; AIS: 0.89, rok: 2023
    Method of publishing: Open access
    Result website:
    https://doi.org/10.1002/chem.202402151DOI: https://doi.org/10.1002/chem.202402151
    Permanent Link: https://hdl.handle.net/11104/0354457
     
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    10.1002chem.202402151.pdf45.6 MBPublisher’s postprintopen-access
     
  9. 9.
    0587089 - ÚOCHB 2025 RIV DE eng J - Journal Article
    Krömer, Matouš - Poštová Slavětínská, Lenka - Hocek, Michal
    Glyco-DNA: Enzymatic Synthesis of Base-modified and Hypermodified DNA Displaying up to Four Different Monosaccharide Units in the Major Groove.
    Chemistry - A European Journal. Roč. 30, č. 48 (2024), č. článku e202402318. ISSN 0947-6539. E-ISSN 1521-3765
    R&D Projects: GA ČR(CZ) GX20-00885X
    Institutional support: RVO:61388963
    Keywords : DNA synthesis * nucleotides * carbohydrates * lectins * glycopolymers
    OECD category: Organic chemistry
    Impact factor: 3.9, year: 2023 ; AIS: 0.89, rok: 2023
    Method of publishing: Open access
    Result website:
    https://doi.org/10.1002/chem.202402318DOI: https://doi.org/10.1002/chem.202402318
    Permanent Link: https://hdl.handle.net/11104/0354386
     
  10. 10.
    0585794 - ÚOCHB 2025 RIV US eng J - Journal Article
    Fleuti, Marianne - Sánchez Quirante, Tania - Poštová Slavětínská, Lenka - Tloušťová, Eva - Tichý, Michal - Gurská, S. - Džubák, P. - Hajdúch, M. - Hocek, Michal
    Synthesis and Biological Profiling of Quinolino-Fused 7-Deazapurine Nucleosides.
    ACS Omega. Roč. 9, č. 18 (2024), s. 20557-20570. ISSN 2470-1343. E-ISSN 2470-1343
    R&D Projects: GA MŠMT LX22NPO5102
    Research Infrastructure: CZ-OPENSCREEN IV - 90252; EATRIS-CZ IV - 90253
    Institutional support: RVO:61388963
    Keywords : ·LiCl * enzymatic incorporation * analogs
    OECD category: Organic chemistry
    Impact factor: 3.7, year: 2023 ; AIS: 0.639, rok: 2023
    Method of publishing: Open access
    Result website:
    https://doi.org/10.1021/acsomega.4c02031DOI: https://doi.org/10.1021/acsomega.4c02031
    Permanent Link: https://hdl.handle.net/11104/0353484
     
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    10.1021acsomega.4c02031.pdf52.5 MBPublisher’s postprintopen-access
     

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