Search results
- 1.0642428 - ÚOCHB 2026 RIV GB eng J - Journal Article
Pokorná, Jana - Hadzima, Martin - Křenková, Alena - Smith, Joshua David - Šubr, Vladimír - Kryštůfek, Robin - Hubálek, Martin - Starková, Jana - Šrámková, Karolína - Etrych, Tomáš - Kostka, Libor - Sedlák, František - Konvalinka, Jan - Šácha, Pavel
Uncovering the Glutamate Carboxypeptidase II Microenvironment Using a Multi-labeling Proteomic Approach.
Scientific Reports. (2025). ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA ČR(CZ) GA23-05642S; GA MŠMT LX22NPO5102; GA MZd(CZ) NU22-03-00318
Institutional support: RVO:61388963 ; RVO:61389013
Keywords : PSMA * protein proximity labeling * iBody * HRP * µMap * riboflavin
OECD category: Biochemistry and molecular biology
Impact factor: 3.9, year: 2024 ; AIS: 1.029, rok: 2024
Method of publishing: Open access
Result website:
https://doi.org/10.1038/s41598-025-28826-5DOI: https://doi.org/10.1038/s41598-025-28826-5
Permanent Link: https://hdl.handle.net/11104/0372342File Download Size Commentary Version Access 10.1038s41598-025-28826-5.pdf 0 1.1 MB Publisher’s postprint open-access - 2.0639946 - ÚMCH 2026 RIV US eng J - Journal Article
Pytlíková, Sára - Jiang, B. - Woldřichová, Lucie - Kotalík, Kevin - Androvič, Ladislav - Gao, S. - Šubr, Vladimír - Rumlerová, Anna - Pola, Robert - Podhorská, Natália - Filipová, Marcela - Zhang, M. - Pechar, Michal - Fang, J. - Laga, Richard - Etrych, Tomáš
Polymer nanomedicines with pH-triggered pirarubicin release: revealing the role of carrier hydrophilicity and release kinetics in anticancer performance.
Biomacromolecules. Roč. 26, č. 10 (2025), s. 7013-7023. ISSN 1525-7797. E-ISSN 1526-4602
R&D Projects: GA MŠMT LX22NPO5102; GA MŠMT(CZ) LUAUS24239
Institutional support: RVO:61389013
Keywords : nanomedicines * pH-sensitive drug release * hydrophilic carriers
OECD category: Polymer science
Impact factor: 5.4, year: 2024 ; AIS: 0.95, rok: 2024
Method of publishing: Open access
Result website:
https://pubs.acs.org/doi/10.1021/acs.biomac.5c01344DOI: https://doi.org/10.1021/acs.biomac.5c01344
Permanent Link: https://hdl.handle.net/11104/0370380File Download Size Commentary Version Access 0639946.pdf 0 5.2 MB CC-BY 4.0 Publisher’s postprint open-access - 3.0587571 - ÚOCHB 2025 RIV US eng J - Journal Article
Hadzima, Martin - Faucher, F. F. - Blažková, K. - Yim, J. J. - Guerra, M. - Chen, S. - Woods, E. C. - Park, K. W. - Šácha, Pavel - Šubr, Vladimír - Kostka, Libor - Etrych, Tomáš - Majer, Pavel - Konvalinka, Jan - Bogyo, M.
Polymer-Tethered Quenched Fluorescent Probes for Enhanced Imaging of Tumor-Associated Proteases.
ACS Sensors. Roč. 9, č. 7 (2024), s. 3720-3729. ISSN 2379-3694. E-ISSN 2379-3694
R&D Projects: GA MŠMT LX22NPO5102; GA MŠMT(CZ) EF18_053/0016940; GA MZd(CZ) NU21-08-00280; GA ČR(CZ) GA23-05642S
Institutional support: RVO:61388963 ; RVO:61389013
Keywords : fluorescence * imaging * protease * cancer * HPMA copolymer * iBody
OECD category: Polymer science; Polymer science (UMCH-V)
Impact factor: 9.1, year: 2024 ; AIS: 1.539, rok: 2024
Method of publishing: Open access
Result website:
https://doi.org/10.1021/acssensors.4c00912DOI: https://doi.org/10.1021/acssensors.4c00912
Permanent Link: https://hdl.handle.net/11104/0354701File Download Size Commentary Version Access 0587571.pdf 2 6.2 MB Publisher’s postprint open-access 10.1021acssensors.4c00912.pdf 3 6.2 MB Publisher’s postprint open-access - 4.0586357 - ÚOCHB 2025 RIV NL eng J - Journal Article
Zamani, Mohammad Reza - Hadzima, Martin - Blažková, Kristýna - Šubr, Vladimír - Ormsby, Tereza - Celis-Gutierrez, J. - Malissen, B. - Kostka, Libor - Etrych, Tomáš - Šácha, Pavel - Konvalinka, Jan
Polymer-based antibody mimetics (iBodies) target human PD-L1 and function as a potent immune checkpoint blocker.
Journal of Biological Chemistry. Roč. 300, č. 6 (2024), č. článku 107325. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA MŠMT LX22NPO5102; GA ČR(CZ) GA23-05642S
Institutional support: RVO:61388963 ; RVO:61389013
Keywords : PD-1 * PD-L1 * immune checkpoint * HPMA copolymer * antibody mimetic * T-cell * inhibitor * immunotherapy * immunosuppression * tumor immunology
OECD category: Biochemistry and molecular biology; Polymer science (UMCH-V)
Impact factor: 3.9, year: 2024 ; AIS: 1.458, rok: 2024
Method of publishing: Open access
Result website:
https://doi.org/10.1016/j.jbc.2024.107325DOI: https://doi.org/10.1016/j.jbc.2024.107325
Permanent Link: https://hdl.handle.net/11104/0353904File Download Size Commentary Version Access 0586357.pdf 2 1.6 MB Publisher’s postprint open-access 10.1016j.jbc.2024.107325.pdf 8 1.6 MB Publisher’s postprint open-access - 5.0583958 - ÚMCH 2025 RIV CH eng J - Journal Article
Šubr, Vladimír - Kostka, Libor - Plicka, J. - Sedláček, O. - Etrych, Tomáš
Highly effective synthetic polymer-based blockers of non-specific interactions in immunochemical analyses.
Polymers. Roč. 16, č. 6 (2024), č. článku 758. ISSN 2073-4360. E-ISSN 2073-4360
R&D Projects: GA ČR(CZ) GA23-05642S; GA TA ČR(CZ) TN02000122; GA MŠMT LX22NPO5102
Institutional support: RVO:61389013
Keywords : HPMA copolymer * blocker * non-specific interactions
OECD category: Polymer science
Impact factor: 4.9, year: 2024 ; AIS: 0.7, rok: 2024
Method of publishing: Open access
Result website:
https://www.mdpi.com/2073-4360/16/6/758DOI: https://doi.org/10.3390/polym16060758
Permanent Link: https://hdl.handle.net/11104/0352006File Download Size Commentary Version Access 0583958.pdf 2 2.2 MB Creative Commons Attribution (CC BY) license Publisher’s postprint open-access - 6.0580702 - MBÚ 2025 RIV NL eng J - Journal Article
Kovář, Marek - Šubr, Vladimír - Běhalová, Kateřina - Studenovský, Martin - Starenko, Daniil - Kovářová, Jiřina - Procházková, Petra - Etrych, Tomáš - Kostka, Libor
Chemosensitization of tumors via simultaneous delivery of STAT3 inhibitor and doxorubicin through HPMA copolymer-based nanotherapeutics with pH-sensitive activation.
Nanomedicine: Nanotechnology, Biology and Medicine. Roč. 56, February 2024 (2024), s. 102730. ISSN 1549-9634. E-ISSN 1549-9642
R&D Projects: GA MZd(CZ) NU21-03-00273; GA MŠMT LX22NPO5102
Institutional support: RVO:61388971 ; RVO:61389013
Keywords : STAT3 inhibitor * Doxorubicin * HPMA copolymer carrier * pH-sensitive drug * release
OECD category: Pharmacology and pharmacy; Medicinal chemistry (UMCH-V)
Impact factor: 4.6, year: 2024 ; AIS: 0.775, rok: 2024
Method of publishing: Open access
Result website:
https://www.sciencedirect.com/science/article/pii/S1549963423000813DOI: https://doi.org/10.1016/j.nano.2023.102730
Permanent Link: https://hdl.handle.net/11104/0349459File Download Size Commentary Version Access 0580702.pdf 10 5 MB CC BY license Publisher’s postprint open-access Kovar et al_Nanomedicine.pdf 0 5 MB Publisher’s postprint open-access - 7.0578323 - ÚMCH 2024 RIV NL eng J - Journal Article
Pechar, Michal - Král, Vlastimil - Kracíková, Lucie - Androvič, Ladislav - Hrdá, Eliška - Pola, Robert - Pytlíková, Sára - Studenovský, Martin - Kostka, Libor - Šubr, Vladimír - Etrych, Tomáš - Kočková, Olga - Ferreira Mendes, Jessica Marianne - Fábry, Milan - Laga, Richard
Tumor-specific targeting of polymer drug delivery systems with recombinant proteins bound via tris(nitrilotriacetic acid).
International Journal of Pharmaceutics. Roč. 648, 15 December (2023), č. článku 123619. ISSN 0378-5173. E-ISSN 1873-3476
R&D Projects: GA MŠMT LX22NPO5102
Institutional support: RVO:61389013 ; RVO:61388963
Keywords : hydrophilic polymers * thermo-responsive polymers * polymer drug delivery system
OECD category: Polymer science; Biochemistry and molecular biology (UOCHB-X)
Impact factor: 5.3, year: 2023 ; AIS: 0.748, rok: 2023
Method of publishing: Open access
Result website:
https://www.sciencedirect.com/science/article/pii/S0378517323010414?via%3DihubDOI: https://doi.org/10.1016/j.ijpharm.2023.123619
Permanent Link: https://hdl.handle.net/11104/0347753File Download Size Commentary Version Access 0578323.pdf 0 4.4 MB License CC BY 4.0 Publisher’s postprint open-access - 8.0575824 - ÚMCH 2024 RIV AU eng J - Journal Article
Tavares, Marina Rodrigues - Islam, R. - Šubr, Vladimír - Hackbarth, S. - Gao, S. - Yang, K. - Lobaz, Volodymyr - Fang, J. - Etrych, Tomáš
Polymer theranostics with multiple stimuli-based activation of photodynamic therapy and tumor imaging.
Theranostics. Roč. 13, č. 14 (2023), s. 4952-4973. ISSN 1838-7640. E-ISSN 1838-7640
R&D Projects: GA MZd(CZ) NU21-08-00280; GA MŠMT LX22NPO5102
Grant - others:AV ČR(CZ) JSPS-22-01
Program: Bilaterální spolupráce
Institutional support: RVO:61389013
Keywords : fluorescence imaging * photodynamic therapy * pH-responsive theranostics
OECD category: Polymer science
Impact factor: 12.4, year: 2023 ; AIS: 2.499, rok: 2023
Method of publishing: Open access
Result website:
https://www.thno.org/v13p4952DOI: https://doi.org/10.7150/thno.86211
Permanent Link: https://hdl.handle.net/11104/0346030File Download Size Commentary Version Access 0575824.pdf 2 8.4 MB License CC BY Publisher’s postprint open-access - 9.0571287 - ÚMCH 2024 RIV CH eng J - Journal Article
Hackbarth, S. - Gao, S. - Šubr, Vladimír - Lin, L. - Pohl, J. - Etrych, Tomáš - Fang, J.
Singlet oxygen in vivo: it is all about intensity - part 2.
Journal of Personalized Medicine. Roč. 13, č. 5 (2023), č. článku 781. E-ISSN 2075-4426
R&D Projects: GA MZd(CZ) NU21-08-00280; GA MŠMT LX22NPO5102
Institutional support: RVO:61389013
Keywords : photodynamic therapy * singlet oxygen * time-resolved phosphorescence
OECD category: Polymer science
Impact factor: 3, year: 2023 ; AIS: 0.682, rok: 2023
Method of publishing: Open access
Result website:
https://www.mdpi.com/2075-4426/13/5/781DOI: https://doi.org/10.3390/jpm13050781
Permanent Link: https://hdl.handle.net/11104/0344181File Download Size Commentary Version Access 0571287.pdf 1 3.2 MB License CC BY Publisher’s postprint open-access - 10.0565942 - ÚMCH 2024 RIV US eng J - Journal Article
Islam, R. - Kotalík, Kevin - Šubr, Vladimír - Gao, S. - Zhou, J.-R. - Yokomizo, K. - Etrych, Tomáš - Fang, J.
HPMA copolymer conjugated 5-aminolevulinic acid exhibits superior efficacy for photodynamic therapy with tumor-responsive and targeting properties.
Nanomedicine: Nanotechnology, Biology and Medicine. Roč. 48, February (2023), č. článku 102636. ISSN 1549-9634. E-ISSN 1549-9642
R&D Projects: GA MŠMT LX22NPO5102
Grant - others:AV ČR(CZ) JSPS-22-01
Program: Bilaterální spolupráce
Institutional support: RVO:61389013
Keywords : HPMA copolymer * 5-aminolevulinic acid * photodynamic therapy
OECD category: Polymer science
Impact factor: 4.2, year: 2023 ; AIS: 0.805, rok: 2023
Method of publishing: Open access
Result website:
https://www.sciencedirect.com/science/article/pii/S1549963422001228?via%3DihubDOI: https://doi.org/10.1016/j.nano.2022.102636
Permanent Link: https://hdl.handle.net/11104/0337420File Download Size Commentary Version Access 0565942.pdf 0 1.5 MB CC BY License Publisher’s postprint open-access