Search results

  1. 1.
    0580702 - MBÚ 2025 RIV NL eng J - Journal Article
    Kovář, Marek - Šubr, Vladimír - Běhalová, Kateřina - Studenovský, Martin - Starenko, Daniil - Kovářová, Jiřina - Procházková, Petra - Etrych, Tomáš - Kostka, Libor
    Chemosensitization of tumors via simultaneous delivery of STAT3 inhibitor and doxorubicin through HPMA copolymer-based nanotherapeutics with pH-sensitive activation.
    Nanomedicine: Nanotechnology, Biology and Medicine. Roč. 56, February 2024 (2024), s. 102730. ISSN 1549-9634. E-ISSN 1549-9642
    R&D Projects: GA MZd(CZ) NU21-03-00273; GA MŠMT LX22NPO5102
    Institutional support: RVO:61388971 ; RVO:61389013
    Keywords : STAT3 inhibitor * Doxorubicin * HPMA copolymer carrier * pH-sensitive drug * release
    OECD category: Pharmacology and pharmacy; Medicinal chemistry (UMCH-V)
    Impact factor: 5.4, year: 2022
    Method of publishing: Open access
    https://www.sciencedirect.com/science/article/pii/S1549963423000813
    Permanent Link: https://hdl.handle.net/11104/0349459
    FileDownloadSizeCommentaryVersionAccess
    0580702.pdf15 MBCC BY licensePublisher’s postprintopen-access
    Kovar et al_Nanomedicine.pdf05 MBPublisher’s postprintopen-access
     
     
  2. 2.
    0580623 - ÚMCH 2025 RIV GB eng J - Journal Article
    Pytlíková, Sára - Pechar, Michal - Chytil, Petr - Studenovský, Martin - Pola, Robert - Kotrchová, Lenka - Konefal, Rafal - Čtveráčková, Lucie - Laga, Richard - Pankrác, J. - Gao, S. - Jiang, B. - Yang, K. - Fang, J. - Filipová, Marcela - Etrych, Tomáš
    Highly hydrophilic methacrylamide-based copolymers as precursors for polymeric nanomedicines containing anthracyclines.
    European Polymer Journal. Roč. 205, 7 February (2024), č. článku 112756. ISSN 0014-3057. E-ISSN 1873-1945
    R&D Projects: GA MŠMT LX22NPO5102; GA ČR(CZ) GA22-12483S
    Grant - others:AV ČR(CZ) JSPS-22-01
    Program: Bilaterální spolupráce
    Institutional support: RVO:61389013
    Keywords : drug delivery systems * polymer drug carriers * N‑(1,3‑dihydroxyprop-2-yl) methacrylamide
    OECD category: Polymer science
    Impact factor: 6, year: 2022
    Method of publishing: Open access
    https://www.sciencedirect.com/science/article/pii/S001430572400017X?via%3Dihub
    Permanent Link: https://hdl.handle.net/11104/0349466
    FileDownloadSizeCommentaryVersionAccess
    0580623.pdf01.5 MBCC BY LicensePublisher’s postprintopen-access
     
     
  3. 3.
    0578323 - ÚMCH 2024 RIV NL eng J - Journal Article
    Pechar, Michal - Král, Vlastimil - Kracíková, Lucie - Androvič, Ladislav - Hrdá, Eliška - Pola, Robert - Pytlíková, Sára - Studenovský, Martin - Kostka, Libor - Šubr, Vladimír - Etrych, Tomáš - Kočková, Olga - Ferreira Mendes, Jessica Marianne - Fábry, Milan - Laga, Richard
    Tumor-specific targeting of polymer drug delivery systems with recombinant proteins bound via tris(nitrilotriacetic acid).
    International Journal of Pharmaceutics. Roč. 648, 15 December (2023), č. článku 123619. ISSN 0378-5173. E-ISSN 1873-3476
    R&D Projects: GA MŠMT LX22NPO5102
    Institutional support: RVO:61389013 ; RVO:61388963
    Keywords : hydrophilic polymers * thermo-responsive polymers * polymer drug delivery system
    OECD category: Polymer science; Biochemistry and molecular biology (UOCHB-X)
    Impact factor: 5.8, year: 2022
    Method of publishing: Open access
    https://www.sciencedirect.com/science/article/pii/S0378517323010414?via%3Dihub
    Permanent Link: https://hdl.handle.net/11104/0347753
    FileDownloadSizeCommentaryVersionAccess
    0578323.pdf04.4 MBLicense CC BY 4.0Publisher’s postprintopen-access
     
     
  4. 4.
    0567633 - ÚMCH 2024 RIV CH eng J - Journal Article
    Pola, Robert - Vícha, Matěj - Trousil, Jiří - Grosmanová, Eliška - Pechar, Michal - Rumlerová, Anna - Studenovský, Martin - Kučerová, E. - Ulbrich, P. - Vokatá, B. - Etrych, Tomáš
    Polymer-antimicrobial peptide constructs with tailored drug-release behavior.
    Pharmaceutics. Roč. 15, č. 2 (2023), č. článku 406. E-ISSN 1999-4923
    R&D Projects: GA ČR(CZ) GA20-04790S
    Institutional support: RVO:61389013
    Keywords : antimicrobial peptides * HPMA copolymers * bacteria
    OECD category: Polymer science
    Impact factor: 5.4, year: 2022
    Method of publishing: Open access
    https://www.mdpi.com/1999-4923/15/2/406
    Permanent Link: https://hdl.handle.net/11104/0341392
     
     
  5. 5.
    0561407 - ÚMCH 2023 RIV US eng J - Journal Article
    Pechar, Michal - Pola, Robert - Studenovský, Martin - Bláhová, Markéta - Grosmanová, Eliška - Dydowiczová, Aneta - Filipová, Marcela - Islam, R. - Gao, S. - Fang, J. - Etrych, Tomáš
    Polymer nanomedicines with enzymatically triggered activation: a comparative study of in vitro and in vivo anti-cancer efficacy related to the spacer structure.
    Nanomedicine: Nanotechnology, Biology and Medicine. Roč. 46, November (2022), č. článku 102597. ISSN 1549-9634. E-ISSN 1549-9642
    R&D Projects: GA ČR(CZ) GA22-12483S; GA MŠMT(CZ) LTAUSA18083
    Grant - others:AV ČR(CZ) JSPS-22-01
    Program: Bilaterální spolupráce
    Institutional support: RVO:61389013
    Keywords : drug delivery * polymer cancerostatics * enzymatic release
    OECD category: Polymer science
    Impact factor: 5.4, year: 2022
    Method of publishing: Limited access
    https://www.sciencedirect.com/science/article/pii/S1549963422000831
    Permanent Link: https://hdl.handle.net/11104/0334099
     
     
  6. 6.
    0559474 - ÚMCH 2023 RIV US eng J - Journal Article
    Kousalová, Jana - Šírová, Milada - Kostka, Libor - Šubr, Vladimír - Kovářová, Jiřina - Běhalová, Kateřina - Studenovský, Martin - Kovář, Marek - Etrych, Tomáš
    Metastatic spread inhibition of cancer cells through stimuli-sensitive HPMA copolymer-bound actinonin nanomedicines.
    Nanomedicine: Nanotechnology, Biology and Medicine. Roč. 44, August (2022), č. článku 102578. ISSN 1549-9634. E-ISSN 1549-9642
    R&D Projects: GA MŠMT(CZ) LTAUSA18083
    Grant - others:AV ČR(CZ) JSPS-22-01
    Program: Bilaterální spolupráce
    Institutional support: RVO:61389013 ; RVO:61388971
    Keywords : matrix metalloproteinases * metastases * actinonin
    OECD category: Polymer science; Oncology (MBU-M)
    Impact factor: 5.4, year: 2022
    Method of publishing: Limited access
    https://www.sciencedirect.com/science/article/pii/S1549963422000648?via%3Dihub
    Permanent Link: https://hdl.handle.net/11104/0332758
     
     
  7. 7.
    0558143 - ÚMCH 2023 RIV CH eng J - Journal Article
    Studenovský, Martin - Rumlerová, Anna - Kovářová, Jiřina - Dvořáková, Barbora - Sivák, Ladislav - Kostka, Libor - Berdár, Daniel - Etrych, Tomáš - Kovář, Marek
    HPMA copolymer mebendazole conjugate allows systemic administration and possesses antitumour activity in vivo.
    Pharmaceutics. Roč. 14, č. 6 (2022), č. článku 1201. E-ISSN 1999-4923
    R&D Projects: GA ČR(CZ) GA19-05649S; GA MŠMT(CZ) LTAUSA18083
    Grant - others:AV ČR(CZ) JSPS-22-01
    Program: Bilaterální spolupráce
    Institutional support: RVO:61389013 ; RVO:61388971
    Keywords : mebendazole * drug delivery * cancer therapy
    OECD category: Polymer science; Pharmacology and pharmacy (MBU-M)
    Impact factor: 5.4, year: 2022
    Method of publishing: Open access
    https://www.mdpi.com/1999-4923/14/6/1201
    Permanent Link: https://hdl.handle.net/11104/0333076
     
     
  8. 8.
    0545100 - ÚMCH 2022 RIV CH eng J - Journal Article
    Studenovský, Martin - Rumlerová, Anna - Kostka, Libor - Etrych, Tomáš
    HPMA-based polymer conjugates for repurposed drug mebendazole and other imidazole-based therapeutics.
    Polymers. Roč. 13, č. 15 (2021), č. článku 2530. E-ISSN 2073-4360
    R&D Projects: GA ČR(CZ) GA19-01417S; GA ČR(CZ) GA19-05649S; GA MŠMT(CZ) LTAUSA18083
    Institutional support: RVO:61389013
    Keywords : mebendazole * drug delivery * drug repurposing
    OECD category: Polymer science
    Impact factor: 4.967, year: 2021
    Method of publishing: Open access
    https://www.mdpi.com/2073-4360/13/15/2530
    Permanent Link: http://hdl.handle.net/11104/0321902
     
     
  9. 9.
    0542896 - MBÚ 2022 RIV NL eng J - Journal Article
    Sivák, Ladislav - Šubr, Vladimír - Kovářová, Jiřina - Dvořáková, Barbora - Šírová, Milada - Říhová, Blanka - Randárová, Eva - Kraus, Michal - Tomala, Jakub - Studenovský, Martin - Vondráčková, Michaela - Sedláček, Radislav - Makovický, Peter - Fučíková, J. - Vošahlíková, Š. - Spíšek, R. - Kostka, Libor - Etrych, Tomáš - Kovář, Marek
    Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling.
    Journal of Controlled Release. Roč. 332, APR 10 2021 (2021), s. 563-580. ISSN 0168-3659. E-ISSN 1873-4995
    R&D Projects: GA ČR(CZ) GA19-05649S; GA MŠMT(CZ) LM2015040; GA MŠMT(CZ) ED1.1.00/02.0109
    Research Infrastructure: CCP - 90040
    Institutional support: RVO:61388971 ; RVO:61389013 ; RVO:68378050
    Keywords : Ritonavir derivate * Polymer carrier * pH-controlled release * Antitumor activity * Proteasome inhibition * STAT3 signaling inhibition
    OECD category: Microbiology; Polymer science (UMCH-V)
    Impact factor: 11.467, year: 2021
    Method of publishing: Limited access
    https://www.sciencedirect.com/science/article/pii/S0168365921001267
    Permanent Link: http://hdl.handle.net/11104/0320232
     
     
  10. 10.
    0534797 - ÚMCH 2021 RIV DE eng J - Journal Article
    Sýkora, D. - Záruba, K. - Butnariu, M. - Tatar, A. - Pham, H. M. - Studenovský, Martin - Řezanka, P. - Král, V.
    New multimodal stationary phases prepared by Ugi multicomponent approach.
    Journal of Separation Science. Roč. 43, č. 22 (2020), s. 4178-4190. ISSN 1615-9306. E-ISSN 1615-9314
    Institutional support: RVO:61389013
    Keywords : hydrophilic interaction * hydrophobic interaction * ion-exchange interaction
    OECD category: Polymer science
    Impact factor: 3.645, year: 2020
    Method of publishing: Limited access
    https://onlinelibrary.wiley.com/doi/10.1002/jssc.202000587
    Permanent Link: http://hdl.handle.net/11104/0313251
     
     

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