Search results
- 1.0473875 - MBÚ 2018 RIV NL eng J - Journal Article
Šírová, Milada - Strohalm, Jiří - Chytil, Petr - Lidický, Ondřej - Tomala, Jakub - Říhová, Blanka - Etrych, Tomáš
The structure of polymer carriers controls the efficacy of the experimental combination treatment of tumors with HPMA copolymer conjugates carrying doxorubicin and docetaxel.
Journal of Controlled Release. Roč. 246, JAN 28 (2017), s. 1-11. ISSN 0168-3659. E-ISSN 1873-4995
R&D Projects: GA ČR(CZ) GA14-12742S; GA ČR(CZ) GA15-02986S; GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) ED1.1.00/02.0109; GA MZd(CZ) NV16-28600A; GA ČR(CZ) GAP301/12/1254
Institutional support: RVO:61388971 ; RVO:61389013
Keywords : Drug delivery * HPMA * Doxorubicin
OECD category: Immunology; Polymer science (UMCH-V)
Impact factor: 7.877, year: 2017
Permanent Link: http://hdl.handle.net/11104/0270992 - 2.0473557 - MBÚ 2018 RIV GB eng J - Journal Article
Sivák, Ladislav - Šubr, Vladimír - Tomala, Jakub - Říhová, Blanka - Strohalm, Jiří - Etrych, Tomáš - Kovář, Marek
Overcoming multidrug resistance via simultaneous delivery of cytostatic drug and P-glycoprotein inhibitor to cancer cells by HPMA copolymer conjugate.
Biomaterials. Roč. 115, JAN 2017 (2017), s. 65-80. ISSN 0142-9612. E-ISSN 1878-5905
R&D Projects: GA ČR(CZ) GAP301/12/1254; GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:61388971 ; RVO:61389013
Keywords : Multidrug resistance * P-glycoprotein * Doxorubicin
OECD category: Microbiology; Polymer science (UMCH-V)
Impact factor: 8.806, year: 2017
Permanent Link: http://hdl.handle.net/11104/0270692 - 3.0463915 - MBÚ 2017 RIV NL eng J - Journal Article
Tomalová, Barbora - Šírová, Milada - Rossmann, Pavel - Pola, Robert - Strohalm, Jiří - Chytil, Petr - Černý, Viktor - Tomala, Jakub - Kabešová, Martina - Říhová, Blanka - Ulbrich, Karel - Etrych, Tomáš - Kovář, Marek
The structure-dependent toxicity, pharmacokinetics and anti-tumour activity of HPMA copolymer conjugates in the treatment of solid tumours and leukaemia.
Journal of Controlled Release. Roč. 223, 10 February (2016), s. 1-10. ISSN 0168-3659. E-ISSN 1873-4995
R&D Projects: GA ČR(CZ) GAP301/11/0325; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:61388971 ; RVO:61389013
Keywords : HPMA * Doxorubicin * Structure
Subject RIV: EE - Microbiology, Virology; CD - Macromolecular Chemistry (UMCH-V)
Impact factor: 7.786, year: 2016
Permanent Link: http://hdl.handle.net/11104/0263061 - 4.0458826 - ÚOCHB 2017 RIV DE eng J - Journal Article
Šácha, Pavel - Knedlík, Tomáš - Schimer, Jiří - Tykvart, Jan - Parolek, Jan - Navrátil, Václav - Dvořáková, Petra - Sedlák, František - Ulbrich, Karel - Strohalm, Jiří - Majer, Pavel - Šubr, Vladimír - Konvalinka, Jan
iBodies: Modular Synthetic Antibody Mimetics Based on Hydrophilic Polymers Decorated with Functional Moieties.
Angewandte Chemie - International Edition. Roč. 55, č. 7 (2016), s. 2356-2360. ISSN 1433-7851. E-ISSN 1521-3773
R&D Projects: GA ČR GBP208/12/G016; GA MŠMT LO1302
Institutional support: RVO:61388963 ; RVO:61389013
Keywords : antibody mimetics * HPMA * molecular recognition * polymer conjugates * protein targeting
Subject RIV: CE - Biochemistry; CD - Macromolecular Chemistry (UMCH-V)
Impact factor: 11.994, year: 2016
http://onlinelibrary.wiley.com/doi/10.1002/anie.201508642/full
Permanent Link: http://hdl.handle.net/11104/0259057 - 5.0450073 - ÚMCH 2016 RIV CH eng J - Journal Article
Lidický, Ondřej - Janoušková, Olga - Strohalm, Jiří - Alam, M. - Klener, P. - Etrych, Tomáš
Anti-lymphoma efficacy comparison of anti-Cd20 monoclonal antibody-targeted and non-targeted star-shaped polymer-prodrug conjugates.
Molecules. Roč. 20, č. 11 (2015), s. 19849-19864. E-ISSN 1420-3049
R&D Projects: GA MŠMT(CZ) ED1.1.00/02.0109; GA ČR(CZ) GA15-02986S; GA MŠMT(CZ) LO1507
Institutional support: RVO:61389013
Keywords : HPMA copolymers * drug delivery systems * doxorubicin
Subject RIV: CD - Macromolecular Chemistry
Impact factor: 2.465, year: 2015
Permanent Link: http://hdl.handle.net/11104/0252998 - 6.0448356 - MBÚ 2016 RIV US eng J - Journal Article
Votavová, Petra - Tomala, Jakub - Šubr, Vladimír - Strohalm, Jiří - Ulbrich, Karel - Říhová, Blanka - Kovář, Marek
Novel IL-2-Poly(HPMA)Nanoconjugate Based Immunotherapy.
Journal of Biomedical Nanotechnology. Roč. 11, č. 9 (2015), s. 1662-1673. ISSN 1550-7033. E-ISSN 1550-7041
R&D Projects: GA ČR GA13-12885S; GA MŠMT(CZ) ED1.1.00/02.0109
Grant - others:AV ČR(CZ) AP0802
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388971 ; RVO:61389013
Keywords : Interleukin-2 * N-(2-hydroxypropyl)Methacrylamide * Poly(HPMA) Conjugate
Subject RIV: EC - Immunology; EC - Immunology (UMCH-V)
Impact factor: 3.929, year: 2015
Permanent Link: http://hdl.handle.net/11104/0250101 - 7.0439488 - ÚMCH 2015 RIV GB eng J - Journal Article
Etrych, Tomáš - Strohalm, Jiří - Šírová, Milada - Tomalová, Barbora - Rossmann, Pavel - Říhová, Blanka - Ulbrich, Karel - Kovář, Marek
High-molecular weight star conjugates containing docetaxel with high anti-tumor activity and low systemic toxicity in vivo.
Polymer Chemistry. Roč. 6, č. 1 (2015), s. 160-170. ISSN 1759-9954. E-ISSN 1759-9962
R&D Projects: GA ČR GAP301/11/0325; GA ČR GCP207/12/J030; GA MŠMT(CZ) EE2.3.20.0055
Institutional support: RVO:61389013 ; RVO:61388971
Keywords : star polymer * HPMA copolymers * docetaxel
Subject RIV: CD - Macromolecular Chemistry; EC - Immunology (MBU-M)
Impact factor: 5.687, year: 2015
Permanent Link: http://hdl.handle.net/11104/0244872 - 8.0431003 - ÚMCH 2015 RIV US eng J - Journal Article
Šubr, Vladimír - Sivák, Ladislav - Koziolová, Eva - Braunová, Alena - Pechar, Michal - Strohalm, Jiří - Kabešová, Martina - Říhová, Blanka - Ulbrich, Karel - Kovář, Marek
Synthesis of poly[N-(2-hydroxypropyl)methacrylamide] conjugates of inhibitors of the ABC transporter that overcome multidrug resistance in doxorubicin-resistant P388 cells in vitro.
Biomacromolecules. Roč. 15, č. 8 (2014), s. 3030-3043. ISSN 1525-7797. E-ISSN 1526-4602
R&D Projects: GA ČR GAP301/12/1254; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:61389013 ; RVO:61388971
Keywords : N-(2-hydroxypropyl)methacrylamide copolymers * multidrug resistance * P-glycoprotein inhibitors
Subject RIV: CD - Macromolecular Chemistry; FD - Oncology ; Hematology (MBU-M)
Impact factor: 5.750, year: 2014
Permanent Link: http://hdl.handle.net/11104/0236142 - 9.0425011 - MBÚ 2014 RIV NL eng J - Journal Article
Šírová, Milada - Kabešová, Martina - Kovář, Lubomír - Etrych, Tomáš - Strohalm, Jiří - Ulbrich, Karel - Říhová, Blanka
HPMA Copolymer-Bound Doxorubicin Induces Immunogenic Tumor Cell Death.
Current Medicinal Chemistry. Roč. 20, č. 38 (2013), s. 4815-4826. ISSN 0929-8673. E-ISSN 1875-533X
R&D Projects: GA ČR GAP301/12/1254
Institutional support: RVO:61388971 ; RVO:61389013
Keywords : Anti-tumor immune response * calreticulin * heat shock proteins
Subject RIV: CE - Biochemistry
Impact factor: 3.715, year: 2013
Permanent Link: http://hdl.handle.net/11104/0230969 - 10.0391498 - ÚMCH 2014 RIV US eng J - Journal Article
Šubr, Vladimír - Kostka, Libor - Strohalm, Jiří - Etrych, Tomáš - Ulbrich, Karel
Synthesis of well-defined semitelechelic poly[N-(2-hydroxypropyl)methacrylamide] polymers with functional group at the .alpha.-end of the polymer chain by RAFT polymerization.
Macromolecules. Roč. 46, č. 6 (2013), s. 2100-2108. ISSN 0024-9297. E-ISSN 1520-5835
R&D Projects: GA ČR GAP301/12/1254; GA MŠMT EE2.3.30.0029
Institutional support: RVO:61389013
Keywords : RAFT polymerization * N-(2-hydroxypropyl)methacrylamide * semitelechelic polymers
Subject RIV: CD - Macromolecular Chemistry
Impact factor: 5.927, year: 2013
Permanent Link: http://hdl.handle.net/11104/0221256