Search results
- 1.0429114 - ÚOCHB 2015 CZ eng C - Conference Paper (international conference)
Šála, Michal - Dejmek, Milan - Procházková, Eliška - Hřebabecký, Hubert - Rybáček, Jiří - Dračínský, Martin - Novák, Pavel - Rosenbergová, Šárka - Fukal, J. - Sychrovský, Vladimír - Rosenberg, Ivan - Nencka, Radim
Novel conformationally locked nucleosides and nucleotides based on bicyclo[3.2.1]octane scaffold as a pseudosugar moiety.
Chemistry of Nucleic Acid Components. 16th Symposium. Praha: Institute of Organic Chemistry and Biochemistry AS CR, v. v. i, 2014 - (Hocek, M.), s. 379-380. Collection Symposium Series, 14. ISBN 978-80-86241-50-0.
[Symposium on Chemistry of Nucleic Acid Components /16./. Český Krumlov (CZ), 08.06.2014-13.06.2014]
R&D Projects: GA ČR GPP207/12/P625; GA TA ČR TA03010598
Institutional support: RVO:61388963
Keywords : locked nucleosides * LNA
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0234449 - 2.0429111 - ÚOCHB 2015 CZ eng C - Conference Paper (international conference)
Procházková, Eliška - Hřebabecký, Hubert - Nencka, Radim - Dračínský, Martin
Enzymatic decomposition of a locked nucleoside phosphoramidate monitored by 31P NMR spectroscopy.
Chemistry of Nucleic Acid Components. 16th Symposium. Praha: Institute of Organic Chemistry and Biochemistry AS CR, v. v. i, 2014 - (Hocek, M.), s. 356-357. Collection Symposium Series, 14. ISBN 978-80-86241-50-0.
[Symposium on Chemistry of Nucleic Acid Components /16./. Český Krumlov (CZ), 08.06.2014-13.06.2014]
R&D Projects: GA ČR GA13-24880S; GA ČR GPP207/12/P625
Institutional support: RVO:61388963
Keywords : phosphoramidate derivatives * enzymatic hydrolysis * NMR spectroscopy
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0234445 - 3.0428926 - ÚOCHB 2015 CZ eng C - Conference Paper (international conference)
Nencka, Radim - Šála, Michal - Hřebabecký, Hubert - Procházková, Eliška - Mackman, R. - Barauskas, O. - Lee, Y. J. - Tian, Y.
Novel conformationally locked nucleosides and nucleotides.
Chemistry of Nucleic Acid Components. 16th Symposium. Praha: Institute of Organic Chemistry and Biochemistry AS CR, v. v. i, 2014 - (Hocek, M.), s. 119-122. Collection Symposium Series, 14. ISBN 978-80-86241-50-0.
[Symposium on Chemistry of Nucleic Acid Components /16./. Český Krumlov (CZ), 08.06.2014-13.06.2014]
R&D Projects: GA ČR GPP207/12/P625; GA MV VG20102015046
Institutional support: RVO:61388963
Keywords : locked nucleoside analogues * oligonucleotide synthesis
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0234281 - 4.0360803 - ÚOCHB 2012 CZ eng C - Conference Paper (international conference)
Dejmek, Milan - Hřebabecký, Hubert - Šála, Michal - Dračínský, Martin - Nencka, Radim
Synthesis of conformationally locked carbocyclic nucleosides with norbornane as pseudosugar moiety.
Chemistry of Nucleic Acid Components. 15th Symposium. Praha: Institute of Organic Chemistry and Biochemistry AS CR, v. v. i., 2011 - (Hocek, M.), s. 208-215. Collection Symposium Series, 12. ISBN 978-80-86241-37-1.
[Chemistry of Nucleic Acid Components /15./. Český Krumlov (CZ), 05.06.2011-10.06.2011]
R&D Projects: GA MŠMT 1M0508
Institutional research plan: CEZ:AV0Z40550506
Keywords : norbornane * conformationally locked cyrbocyclic nucleosides
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0198268 - 5.0310025 - ÚOCHB 2009 RIV CZ eng C - Conference Paper (international conference)
Pomeisl, Karel - Holý, Antonín - Votruba, Ivan - Nencka, Radim - Pohl, Radek
Facile syntheses of pyrimidine acyclic nucleoside phosphonates and their potential evaluation for biomedical applications.
[Snadné syntézy pyrimidinových acyklických nukleosidfosfonátů a jejich potenciál v biomedicinálních aplikacích.]
Chemistry of Nucleic Acid Components. Praha: Institute of Organic Chemistry and Biochemistry ASCR, 2008 - (Hocek, M.), s. 201-205. Collection Symposium Series, 10. ISBN 978-80-86241-29-6.
[Symposium on Chemistry of Nucleic Acid Components /14./. Český Krumlov (CZ), 08.06.2008-13.06.2008]
R&D Projects: GA MŠMT 1M0508; GA AV ČR 1QS400550501
Institutional research plan: CEZ:AV0Z40550506
Keywords : acyclic nucleoside phosphonates * thymidine phosphorylase * dUTPpase
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0162012 - 6.0309994 - ÚOCHB 2009 RIV CZ eng C - Conference Paper (international conference)
Nencka, Radim - Hřebabecký, Hubert - Votruba, Ivan - Dračínský, Martin - Holý, Antonín
Metalation of 6-halo-2,4-dimethoxypyrimidines as the key step for the synthesis of biologicaly active compounds.
[Metalace 6-halo-2,4-dimethoxypyrimidinů jako klíčový krok pro syntézu biologicky aktivních sloučenin.]
Chemistry of Nucleic Acid Components. Praha: Institute of Organic Chemistry and Biochemistry ASCR, 2008 - (Hocek, M.), s. 249-253. Collection Symposium Series, 10. ISBN 978-80-86241-29-6.
[Symposium on Chemistry of Nucleic Acid Components /14./. Český Krumlov (CZ), 08.06.2008-13.06.2008]
R&D Projects: GA MŠMT 1M0508; GA AV ČR 1QS400550501
Institutional research plan: CEZ:AV0Z40550506
Keywords : pyrimidine * organometallic * cross-coupling * lithiation
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0161994 - 7.0022923 - ÚOCHB 2006 RIV CZ eng C - Conference Paper (international conference)
Nencka, Radim - Votruba, Ivan - Hřebabecký, Hubert - Tloušťová, Eva - Horská, Květoslava - Masojídková, Milena - Holý, Antonín
Design and synthesis of 5,6-disubstituted uracil derivatives as potent inhibitors of thymidine phosphorylase.
[Design a syntéza 5,6-disubstituovaných uracilových derivátů jako účinných inhibitorů thymidinfosforylasy.]
Chemistry of Nucleic Acid Components. Praha: ÚOCHB AV ČR, 2005 - (Hocek, M.), s. 441-442. Collection Symposium Series, 7. ISBN 80-86241-25-4.
[Chemistry of Nucleic Acid Components /13./. Špindlerův Mlýn (CZ), 03.09.2005-09.09.2005]
R&D Projects: GA ČR(CZ) GA203/03/0089
Institutional research plan: CEZ:AV0Z40550506
Keywords : thymidine phosphorylase inhibitor * uracil * angiogenesis
Subject RIV: CC - Organic Chemistry
Permanent Link: http://hdl.handle.net/11104/0111621