Search results
- 1.0194775 - UOCHB-X 20030081 RIV GB eng J - Journal Article
Ingr, Marek - Kondrová, Taťána - Stříšovský, Kvido - Majerová, E. - Konvalinka, Jan
Kinetics of the dimerization of retroviral proteases: The "fireman's grip" and dimerization.
Protein Science. Roč. 12, - (2003), s. 2173-2182. ISSN 0961-8368. E-ISSN 1469-896X
R&D Projects: GA MZd NI6339
Institutional research plan: CEZ:AV0Z4055905
Keywords : retroviral protease * dimerization * HIV protease
Subject RIV: CE - Biochemistry
Impact factor: 3.787, year: 2003
Permanent Link: http://hdl.handle.net/11104/0090446 - 2.0194573 - UOCHB-X 20020244 RIV GB eng J - Journal Article
Weber, Jan - Mesters, J. R. - Lepšík, Martin - Prejdová, Jana - Švec, Martin - Šponarová, Jana - Mlčochová, Petra - Skalická, Kristina - Stříšovský, Kvido - Kondrová, Taťána - Souček, Milan - Machala, L. - Staňková, M. - Vondrášek, Jiří - Klimkait, T. - Kraeusslich, H. G. - Hilgenfeld, R. - Konvalinka, Jan
Unusual binding mode of an HIV-1 protease inhibitor explains its potency against multi-grug-resistant virus strains.
Journal of Molecular Biology. Roč. 324, - (2002), s. 739-754. ISSN 0022-2836. E-ISSN 1089-8638
R&D Projects: GA ČR GA203/00/0828; GA MŠMT LN00A032; GA MZd NI6339
Institutional research plan: CEZ:AV0Z4055905
Keywords : HIV protease inhibitor
Subject RIV: CE - Biochemistry
Impact factor: 5.359, year: 2002
Permanent Link: http://hdl.handle.net/11104/0090248 - 3.0189173 - UMCH-V 20033128 RIV US eng J - Journal Article
Skálová, Tereza - Hašek, Jindřich - Dohnálek, Jan - Petroková, Hana - Buchtelová, Eva - Dušková, Jarmila - Souček, Milan - Majer, Pavel - Kondrová, Taťána - Konvalinka, Jan
An ethylenamine inhibitor binds tightly to both wild type and mutant HIV-1 proteases. Structure and energy study.
Journal of Medicinal Chemistry. Roč. 46, č. 9 (2003), s. 1636-1644. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA AV ČR IAA4050811; GA AV ČR KJB4050312; GA ČR GV203/98/K023; GA ČR GA204/00/P091; GA ČR GA203/00/D117; GA MZd NI6339
Institutional research plan: CEZ:AV0Z4050913; CEZ:AV0Z4055905
Keywords : mutant HIV-1 protease * ethylenamine inhibitor * structure
Subject RIV: CD - Macromolecular Chemistry
Impact factor: 4.820, year: 2003
Permanent Link: http://hdl.handle.net/11104/0085014 - 4.0100873 - UOCHB-X 20043061 RIV CZ eng J - Journal Article
Kožíšek, Milan - Prejdová, Jana - Souček, Milan - Machala, L. - Staňková, M. - Linka, M. - Brůčková, M. - Konvalinka, Jan
Characterisation of mutated proteinases derived from HIV-positive patients: enzime activity, vitality and inhibition.
[Charakterisace mutantních proteas odvozených z HIV-positivních pacientů: enzymová aktivita, vitalita a inhibice.]
Collection of Czechoslovak Chemical Communications. Roč. 69, č. 3 (2004), s. 703-714. ISSN 0010-0765
R&D Projects: GA MZd NI6339
Grant - others:5th Framework(XE) QLK2-CT-2001-02360
Institutional research plan: CEZ:AV0Z4055905
Keywords : enzyme inhibitors * HIV protease * enzyme kinetics
Subject RIV: CE - Biochemistry
Impact factor: 1.062, year: 2004
Permanent Link: http://hdl.handle.net/11104/0008357 - 5.0025455 - ÚOCHB 2006 RIV NL eng J - Journal Article
Prejdová, Jana - Machala, L. - Staňková, M. - Linka, M. - Brůčková, M. - Vandasová, J. - Konvalinka, Jan
Response of HIV positive patients to the long-term salvage therapy by lopinavir/ritonavir.
[Odpověď HIV-positivních pacientů na dlouhodobou léčbu kombinací lopinavir-ritonavir.]
Journal of Clinical Virology. Roč. 33, č. 4 (2005), 319-323. ISSN 1386-6532. E-ISSN 1873-5967
R&D Projects: GA MZd(CZ) NI6339
Grant - others:5th Framework(XE) QLK2-CT-2001-02360
Institutional research plan: CEZ:AV0Z4055905
Keywords : protease inhibitor * salvage therapy * resistance development
Subject RIV: CE - Biochemistry
Impact factor: 2.623, year: 2005
Permanent Link: http://hdl.handle.net/11104/0115841 - 6.0025445 - ÚOCHB 2006 RIV SK eng J - Journal Article
Prejdová, Jana - Weber, Jan - Machala, L. - Reiniš, Milan - Linka, M. - Brůčková, M. - Vandasová, M. - Staňková, M. - Konvalinka, Jan
Long-term analysis of resistance development in HIV-1 positive patients treated with protease and reverse transcriptase inhibitors: Correlation of the genotype and disease progression.
[Dlouhodobá analysa vývoje resistence u HIV-positivních osob léčených inhibitory virové proteasy v České republice: korelace mezi genotypem a postupem choroby.]
Acta virologica. Roč. 49, č. 1 (2005), 29-36. ISSN 0001-723X. E-ISSN 1336-2305
R&D Projects: GA MZd(CZ) NI6339
Grant - others:5th Framework(XE) QLK2-CT-2001-02360
Institutional research plan: CEZ:AV0Z4055905
Keywords : HIV * protease inhibitors * resistance development
Subject RIV: CE - Biochemistry
Impact factor: 0.696, year: 2005
Permanent Link: http://hdl.handle.net/11104/0115831