Search results
- 1.0575940 - ÚEB 2024 RIV GB eng J - Journal Article
Voňka, Petr - Rárová, L. - Bazgier, V. - Tichý, V. - Kolářová, T. - Holčáková, J. - Berka, K. - Kvasnica, Miroslav - Oklešťková, Jana - Kudová, Eva - Strnad, Miroslav - Hrstka, Roman
Small change – big consequence: The impact of C15-C16 double bond in a D‑ring of estrone on estrogen receptor activity.
Journal of Steroid Biochemistry and Molecular Biology. Roč. 233, OCT (2023), č. článku 106365. ISSN 0960-0760
R&D Projects: GA MŠMT(CZ) LM2023055; GA MŠMT LX22NPO5102
Research Infrastructure: e-INFRA CZ - 90140; BBMRI.cz IV - 90233
Institutional support: RVO:61389030 ; RVO:61388963
Keywords : Apoptosis * Docking of steroid library * Estrogen receptor alpha * Luciferase assay * Mitochondrial membrane potential
OECD category: Biochemistry and molecular biology
Impact factor: 4.1, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.jsbmb.2023.106365
Permanent Link: https://hdl.handle.net/11104/0345624File Download Size Commentary Version Access 2023_Vonka_JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY_106365.pdf 3 5.7 MB Other open-access - 2.0532925 - ÚEB 2021 RIV GB eng J - Journal Article
Kubiasová, K. - Montesinos, J. C. - Šamajová, O. - Nisler, Jaroslav - Mik, V. - Semerádová, H. - Plíhalová, Lucie - Novák, Ondřej - Marhavý, P. - Cavallari, N. - Zalabák, D. - Berka, K. - Doležal, Karel - Galuszka, P. - Šamaj, J. - Strnad, Miroslav - Benková, E. - Plíhal, Ondřej - Spíchal, L.
Cytokinin fluoroprobe reveals multiple sites of cytokinin perception at plasma membrane and endoplasmic reticulum.
Nature Communications. Roč. 11, č. 1 (2020), č. článku 4285. E-ISSN 2041-1723
R&D Projects: GA MŠMT(CZ) EF16_019/0000827; GA ČR(CZ) GA16-04184S
Institutional support: RVO:61389030
Keywords : LIGAND-BINDING PROPERTIES * ARABIDOPSIS-THALIANA * HISTIDINE KINASE
OECD category: Biochemistry and molecular biology
Impact factor: 14.919, year: 2020
Method of publishing: Open access
http://doi.org/10.1038/s41467-020-17949-0
Permanent Link: http://hdl.handle.net/11104/0311304File Download Size Commentary Version Access 2020_Kubiasova_NATURE COMMUNICATIONS_4285.pdf 3 3.5 MB Other open-access - 3.0509260 - ÚEB 2020 RIV FR eng J - Journal Article
Jorda, Radek - Řezníčková, Eva - Kiełczewska, U. - Maj, J. - Morzycki, J.W. - Siergiejczyk, L. - Bazgier, Václav - Berka, K. - Rárová, Lucie - Wojtkielewicz, A.
Synthesis of novel galeterone derivatives and evaluation of their in vitro activity against prostate cancer cell lines.
European Journal of Medicinal Chemistry. Roč. 179, OCT 1 (2019), s. 483-492. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA ČR(CZ) GA19-01383S; GA MŠMT(CZ) LM2015047
Institutional support: RVO:61389030
Keywords : Galeterone * Prostate * Steroid
OECD category: Organic chemistry
Impact factor: 5.573, year: 2019
Method of publishing: Open access
http://dx.doi.org/10.1016/j.ejmech.2019.06.040
Permanent Link: http://hdl.handle.net/11104/0300005File Download Size Commentary Version Access 2019_Jorda_EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY_483.pdf 1 2.2 MB Other open-access - 4.0507579 - ÚFCH JH 2020 RIV CZ cze J - Journal Article
Berka, K. - Sršeň, Š. - Slavíček, Petr
Je strojové učení budoucností teoretické chemie?
[Is machine learning the future of theoretical chemistry?]
Chemické listy. Roč. 112, č. 10 (2018), s. 640-647. ISSN 0009-2770. E-ISSN 1213-7103
Institutional support: RVO:61388955
Keywords : Artificial intelligence * Machine learning * Neural networks * qsar * Quantum chemistry * Theoretical chemistry
OECD category: Physical chemistry
Impact factor: 0.311, year: 2018
Method of publishing: Open access
Permanent Link: http://hdl.handle.net/11104/0298567File Download Size Commentary Version Access 0507579.pdf 2 531 KB open access Publisher’s postprint open-access - 5.0490059 - ÚEB 2019 RIV US eng J - Journal Article
Gucký, T. - Řezníčková, Eva - Radošová Muchová, T. - Jorda, Radek - Klejová, Z. - Malínková, V. - Berka, K. - Bazgier, V. - Ajani, Haresh - Lepšík, Martin - Divoký, V. - Kryštof, Vladimír
Discovery of N-2-(4-Amino-cyclohexyl)-9-cyclopentyl-N-6-(4-morpholin-4-ylmethyl-phenyl)-9H-purine-2,6-diamine as a Potent FLT3 Kinase Inhibitor for Acute Myeloid Leukemia with FLT3 Mutations.
Journal of Medicinal Chemistry. Roč. 61, č. 9 (2018), s. 3855-3869. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT(CZ) LO1204; GA MŠMT(CZ) LM2015047; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61389030 ; RVO:61388963
Keywords : INTERNAL TANDEM DUPLICATION * AMG 925 * QUIZARTINIB
OECD category: Hematology; Medicinal chemistry (UOCHB-X)
Impact factor: 6.054, year: 2018
Permanent Link: http://hdl.handle.net/11104/0284356File Download Size Commentary Version Access 2018_Gucky_JOURNAL OF MEDICINAL CHEMISTRY_3855.pdf 1 5.1 MB Other open-access - 6.0485540 - BFÚ 2018 RIV NL eng J - Journal Article
Huličiak, Miroslav - Bazgier, V. - Berka, K. - Kubala, M.
RH421 binds into the ATP-binding site on the Na+/K+-ATPase.
Biochimica Et Biophysica Acta-Biomembranes. Roč. 1859, č. 10 (2017), s. 2113-2122. ISSN 0005-2736. E-ISSN 1879-2642
Institutional support: RVO:68081707
Keywords : sodium-potassium pump * crystal-structure * conformational-changes
OECD category: Biochemistry and molecular biology
Impact factor: 3.438, year: 2017
Permanent Link: http://hdl.handle.net/11104/0280515 - 7.0476344 - ÚEB 2018 RIV FR eng J - Journal Article
Řezníčková, Eva - Tenora, L. - Pospíšilová, Pavlína - Galeta, J. - Jorda, Radek - Berka, K. - Majer, Pavel - Potáček, M. - Kryštof, Vladimír
ALK5 kinase inhibitory activity and synthesis of 2,3,4-substituted 5,5-dimethyl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazoles.
European Journal of Medicinal Chemistry. Roč. 127, FEB 15 (2017), s. 632-642. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA MŠMT(CZ) LO1204; GA ČR(CZ) GA15-15264S; GA MŠMT(CZ) LM2015047
Institutional support: RVO:61389030 ; RVO:61388963
Keywords : i-receptor kinase * beta signaling pathway * small-molecule inhibitor * tgf-beta * domain inhibitors * growth * fibrosis * cancer * potent * series * Transforming growth factor beta receptor I * Protein kinase * Inhibitor * Substituted pyrrolo[1,2-b]pyrazoles
OECD category: Pharmacology and pharmacy; Pharmacology and pharmacy (UOCHB-X)
Impact factor: 4.816, year: 2017
Permanent Link: http://hdl.handle.net/11104/0272863File Download Size Commentary Version Access 2017_Reznickova_EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY_632.pdf 4 1.3 MB Other open-access - 8.0474191 - ÚOCHB 2018 RIV IE eng J - Journal Article
Carazo, A. - Hyršová, L. - Dušek, J. - Chodounská, Hana - Horvátová, A. - Berka, K. - Bazgier, V. - Gan-Schreier, H. - Chamulitrat, W. - Kudová, Eva - Pávek, P.
Acetylated deoxycholic (DCA) and cholic (CA) acids are potent ligands of pregnane X (PXR) receptor.
Toxicology Letters. Roč. 265, Jan 4 (2017), s. 86-96. ISSN 0378-4274. E-ISSN 1879-3169
R&D Projects: GA TA ČR(CZ) TE01020028
Institutional support: RVO:61388963
Keywords : PXR * metabolism * bile acids * nuclear receptors * FXR
OECD category: Organic chemistry
Impact factor: 3.166, year: 2017
Permanent Link: http://hdl.handle.net/11104/0271341 - 9.0467239 - ÚEB 2017 RIV US eng J - Journal Article
Bazgier, Václav - Berka, K. - Otyepka, M. - Banáš, P.
Exponential Repulsion Improves Structural Predictability of Molecular Docking.
Journal of Computational Chemistry. Roč. 37, č. 28 (2016), s. 2485-2494. ISSN 0192-8651. E-ISSN 1096-987X
Institutional support: RVO:61389030
Keywords : cyclin-dependent kinases * structure-based design * scoring functions * cdk2 inhibitors * force-field * ligand interactions * drug discovery * purine * potent * protein-kinase-2 * molecular docking * dock 6.6 * drug design * cyclin-dependent kinase 2 * directory of decoys
Subject RIV: CF - Physical ; Theoretical Chemistry
Impact factor: 3.229, year: 2016
Permanent Link: http://hdl.handle.net/11104/0265352File Download Size Commentary Version Access 2016_Bazgier_JOURNAL OF COMPUTATIONAL CHEMISTRY_2485.pdf 0 445.8 KB Other open-access - 10.0464462 - ÚEB 2017 RIV GB eng J - Journal Article
Kvasnica, Miroslav - Oklešťková, Jana - Bazgier, Václav - Rárová, L. - Kořínková, Petra - Mikulík, Jaromír - Buděšínský, Miloš - Béreš, T. - Berka, K. - Lu, Q. - Russinova, E. - Strnad, Miroslav
Design, synthesis and biological activities of new brassinosteroid analogues with a phenyl group in the side chain.
Organic & Biomolecular Chemistry. Roč. 14, č. 37 (2016), s. 8691-8701. ISSN 1477-0520. E-ISSN 1477-0539
R&D Projects: GA MŠMT(CZ) LO1204; GA ČR GJ15-08202Y; GA MŠMT(CZ) LM2015047
Institutional support: RVO:61389030 ; RVO:61388963
Keywords : ASYMMETRIC DIHYDROXYLATION * IMMUNOMODULATORY ACTIVITY * BRI1
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 3.564, year: 2016
Permanent Link: http://hdl.handle.net/11104/0263315File Download Size Commentary Version Access 2016_Kvasnica_ORGANIC & BIOMOLECULAR CHEMISTRY_8691.pdf 2 1.4 MB Other open-access