Search results
- 1.0579877 - ÚMG 2025 RIV GR eng J - Journal Article
Urban, L. - Novák, S. - Coma, M. - Dvořánková, B. - Lacina, L. - Šáchová, Jana - Hradilová, Miluše - Svatoňová, Petra - Kolář, Michal - Strnad, Hynek - Březinová, J. - Smetana, K. - Gal, P. - Szabó, P.
Unravelling heterogeneous effects of cancer-associated fibroblasts on poor prognosis markers in breast cancer EM-G3 cell line: iIn vitro/i-targeted treatment (anti-IL-6, anti-VEGF-A, anti-MFGE8) based on transcriptomic profiling.
Oncology Reports. Roč. 51, č. 1 (2024), č. článku 3. ISSN 1021-335X. E-ISSN 1791-2431
R&D Projects: GA MŠMT(CZ) EF16_019/0000785; GA MŠMT LX22NPO5102
Institutional support: RVO:68378050
Keywords : expression * growth * hallmarks * diagnosis * vimentin * invasion * epithelial-mesenchymal interaction * cell differentiation * tumor microenvironment * breast cancer * neutralizing antibody
OECD category: Cell biology
Impact factor: 3.8, year: 2023 ; AIS: 0.656, rok: 2023
Method of publishing: Open access
Result website:
https://www.spandidos-publications.com/10.3892/or.2023.8662DOI: https://doi.org/10.3892/or.2023.8662
Permanent Link: https://hdl.handle.net/11104/0348661File Download Size Commentary Version Access Urban L. 2023.pdf 0 1.4 MB Publisher’s postprint open-access - 2.0578397 - MBÚ 2024 RIV US eng J - Journal Article
Táborská, P. - Lukáč, Pavol - Stakheev, Dmitry - Rajsiglová, Lenka - Kalkusová, K. - Strnadová, K. - Lacina, L. - Dvořánková, B. - Novotný, Jiří - Kolář, Michal - Vraná, M. - Čechová, H. - Ransdorfová, S. - Valerianová, M. - Smetana Jr., K. - Vannucci, Luca - Smrž, Daniel
Novel PD-L1- and collagen-expressing patient-derived cell line of undifferentiated pleomorphic sarcoma (JBT19) as a model for cancer immunotherapy.
Scientific Reports. Roč. 13, November (2023), s. 19079. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA MZd(CZ) NU23-08-00071; GA MŠMT LX22NPO5102; GA MŠMT(CZ) LM2018129; GA MŠMT(CZ) EF18_046/0016045
Institutional support: RVO:61388971 ; RVO:68378050
Keywords : B7-H1 Antigen * Histiocytoma * Immunotherapy * ligand * programmed death 1 ligand 1 * malignant fibrous histiocytoma * cell line * nude mouse
OECD category: Immunology; Oncology (UMG-J)
Impact factor: 3.8, year: 2023 ; AIS: 1.061, rok: 2023
Method of publishing: Open access
Result website:
https://www.nature.com/articles/s41598-023-46305-7DOI: https://doi.org/10.1038/s41598-023-46305-7
Permanent Link: https://hdl.handle.net/11104/0347395File Download Size Commentary Version Access Scientific Reports 2023 Taborska Vannucci Smrz IF 4.6 Q2.pdf 7 7.7 MB Publisher’s postprint open-access - 3.0561287 - ÚMG 2023 RIV CH eng J - Journal Article
Talianova, V. - Kejik, Z. - Kaplánek, R. - Veselá, K. - Abramenko, N. - Lacina, L. - Strnadová, K. - Dvořánková, B. - Martásek, P. - Masarik, M. - Houdová Megová, M. - Bušek, P. - Křížová, J. - Zdražilová, L. - Hansíková, H. - Vlčák, Erik - Filimonenko, Vlada - Šedo, A. - Smetana, K. - Jakubek, M.
New-Generation Heterocyclic Bis-Pentamethinium Salts as Potential Cytostatic Drugs with Dual IL-6R and Mitochondria-Targeting Activity.
Pharmaceutics. Roč. 14, č. 8 (2022), č. článku 1712. ISSN 1999-4923. E-ISSN 1999-4923
R&D Projects: GA MŠMT(CZ) EF16_019/0000785; GA MŠMT LX22NPO5102; GA MŠMT(CZ) LM2018129; GA MŠMT(CZ) EF18_046/0016045; GA MŠMT(CZ) EF16_013/0001775
Research Infrastructure: EATRIS-CZ III - 90133
Institutional support: RVO:68378050
Keywords : IL-6R synthetic inhibitors * mitochondria * cancer
OECD category: Pharmacology and pharmacy
Impact factor: 5.4, year: 2022 ; AIS: 0.756, rok: 2022
Method of publishing: Open access
Result website:
https://www.mdpi.com/1999-4923/14/8/1712DOI: https://doi.org/10.3390/pharmaceutics14081712
Permanent Link: https://hdl.handle.net/11104/0333975File Download Size Commentary Version Access pharmaceutics-14-01712.pdf 0 3.4 MB Publisher’s postprint open-access - 4.0555562 - ÚMG 2023 RIV DE eng J - Journal Article
Strnadová, K. - Pfeiferová, Lucie - Přikryl, P. - Dvořánková, B. - Vlčák, Erik - Frýdlová, J. - Vokurka, M. - Novotný, Jiří - Šáchová, Jana - Hradilová, Miluše - Brábek, J. - Šmigová, J. - Rösel, D. - Smetana, K. Jr. - Kolář, Michal - Lacina, L.
Exosomes produced by melanoma cells significantly influence the biological properties of normal and cancer-associated fibroblasts.
Histochemistry and Cell Biology. Roč. 157, č. 2 (2022), s. 153-172. ISSN 0948-6143. E-ISSN 1432-119X
R&D Projects: GA MŠMT(CZ) EF16_019/0000785; GA MŠMT(CZ) LM2018129; GA MŠMT(CZ) EF18_046/0016045; GA MŠMT(CZ) EF16_013/0001775; GA ČR(CZ) GA19-05048S
Institutional support: RVO:68378050
Keywords : Melanoma * Cancer-associated fibroblasts * Exosomes * il-6 * il-8 * Proinflammatory cytokine
OECD category: Cell biology
Impact factor: 2.3, year: 2022 ; AIS: 0.7, rok: 2022
Method of publishing: Open access
Result website:
https://link.springer.com/article/10.1007/s00418-021-02052-2DOI: https://doi.org/10.1007/s00418-021-02052-2
Permanent Link: http://hdl.handle.net/11104/0330026 - 5.0539639 - ÚMG 2021 RIV CH eng J - Journal Article
Novotný, Jiří - Strnadová, K. - Dvořánková, B. - Kocourková, Šárka - Jaksa, R. - Dundr, P. - Pačes, Václav - Smetana, K. - Kolář, Michal - Lacina, L.
Single-Cell RNA Sequencing Unravels Heterogeneity of the Stromal Niche in Cutaneous Melanoma Heterogeneous Spheroids.
Cancers (Basel). Roč. 12, č. 11 (2020), č. článku 3324. ISSN 2072-6694. E-ISSN 2072-6694
R&D Projects: GA MŠMT(CZ) LM2018131
Institutional support: RVO:68378050
Keywords : melanoma * spheroids * fibroblasts * subpopulation * heterogeneity * Interleukin-6 * cytokine * senescence-associated secretory phenotype * extracellular matrix * single-cell sequencing
OECD category: Biochemistry and molecular biology
Impact factor: 6.639, year: 2020 ; AIS: 1.323, rok: 2020
Method of publishing: Open access
Result website:
https://www.mdpi.com/2072-6694/12/11/3324DOI: https://doi.org/10.3390/cancers12113324
Permanent Link: http://hdl.handle.net/11104/0317376 - 6.0518779 - ÚŽFG 2020 RIV GR eng J - Journal Article
Kučera, J. - Strnadová, K. - Dvořánková, B. - Lacina, L. - Krajsová, I. - Štork, J. - Kovářová, Hana - Kupcová Skalníková, Helena - Vodička, Petr - Motlík, Jan - Dundr, P. - Smetana, K. Jr. - Kodet, O.
Serum proteomic analysis of melanoma patients with immunohistochemical profiling of primary melanomas and cultured cells: Pilot study.
Oncology Reports. Roč. 42, č. 5 (2019), s. 1793-1804. ISSN 1021-335X. E-ISSN 1791-2431
R&D Projects: GA MŠMT(CZ) LO1609; GA MŠMT(CZ) EF16_019/0000785
Institutional support: RVO:67985904
Keywords : melanoma * inflammation * microenvironment
OECD category: Oncology
Impact factor: 3.417, year: 2019 ; AIS: 0.594, rok: 2019
Method of publishing: Open access
Result website:
https://www.spandidos-publications.com/10.3892/or.2019.7319DOI: https://doi.org/10.3892/or.2019.7319
Permanent Link: http://hdl.handle.net/11104/0303836 - 7.0507255 - MBÚ 2020 RIV CZ eng J - Journal Article
Fík, Z. - Dvořánková, B. - Kodet, O. - Bouček, Jan - Betka, Jaroslav - Betka, J. - André, S. - Gabius, H. J. - Šnajdr, P. - Smetana, K. Jr. - Chovanec, M.
Towards Dissecting Molecular Routes of Intercellular Communication in the Tumour Microenvironment: Phenotypic Plasticity of Stem Cell-Associated Markers in Co-culture (Carcinoma Cell/Fibroblast) Systems.
Folia Biologica. Roč. 60, č. 5 (2014), s. 205-212. ISSN 0015-5500. E-ISSN 0015-5500
R&D Projects: GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:61388971
Keywords : cancer-associated fibroblasts * cancer stem cell * CD44
OECD category: Microbiology
Impact factor: 1.000, year: 2014 ; AIS: 0.238, rok: 2014
Method of publishing: Open access
Result website:
https://fb.cuni.cz/file/5753/fb2014a0040.pdf
Permanent Link: http://hdl.handle.net/11104/0298279 - 8.0502204 - ÚMG 2019 RIV GR eng J - Journal Article
Kodet, O. - Dvořánková, B. - Bendlová, B. - Sykorova, V. - Krajsova, I. - Štork, J. - Kučera, J. - Szabo, P. - Strnad, Hynek - Kolář, Michal - Vlček, Čestmír - Smetana, K. - Lacina, L.
Microenvironment-driven resistance to B-Raf inhibition in a melanoma patient is accompanied by broad changes of gene methylation and expression in distal fibroblasts.
International Journal of Molecular Medicine. Roč. 41, č. 5 (2018), s. 2687-2703. ISSN 1107-3756. E-ISSN 1791-244X
R&D Projects: GA MZd(CZ) NV16-29032A; GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) ED1.1.00/02.0109
Grant - others:GA MŠk(CZ) LM2015042
Institutional support: RVO:68378050
Keywords : melanoma * cancer-associated fibroblast * genome * transcriptome * gene methylation * stroma * smooth muscle actin * alpha-actin-2 * B-Raf inhibitor * transforming growth factor-1 * stroma-driven resistance
OECD category: Biochemistry and molecular biology
Impact factor: 2.928, year: 2018 ; AIS: 0.571, rok: 2018
DOI: https://doi.org/10.3892/ijmm.2018.3448
Permanent Link: http://hdl.handle.net/11104/0294149 - 9.0502203 - ÚMG 2019 RIV US eng J - Journal Article
Jobe, N.P. - Živicová, V. - Mifkova, A. - Rosel, D. - Dvořánková, B. - Kodet, O. - Strnad, Hynek - Kolář, Michal - Sedo, A. - Smetana, K. - Strnadova, K. - Brabek, J. - Lacina, L.
Fibroblasts potentiate melanoma cells in vitro invasiveness induced by UV-irradiated keratinocytes.
Histochemistry and Cell Biology. Roč. 149, č. 5 (2018), s. 503-516. ISSN 0948-6143. E-ISSN 1432-119X
R&D Projects: GA MZd(CZ) NV16-29032A; GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:68378050
Keywords : Cancer-associated fibroblasts * Keratinocytes * Cancer microenvironment * Cytokine * Chemokine * Melanoma
OECD category: Biochemistry and molecular biology
Impact factor: 2.640, year: 2018 ; AIS: 0.687, rok: 2018
DOI: https://doi.org/10.1007/s00418-018-1650-4
Permanent Link: http://hdl.handle.net/11104/0294147 - 10.0487351 - ÚMG 2018 RIV GR eng J - Journal Article
Živicová, V. - Lacina, L. - Mateu, R. - Smetana, K. - Kavkova, R. - Krejci, E.D. - Grim, M. - Kvasilová, A. - Borský, J. - Strnad, Hynek - Hradilová, Miluše - Šáchová, Jana - Kolář, Michal - Dvořánková, B.
Analysis of dermal fibroblasts isolated from neonatal and child cleft lip and adult skin: Developmental implications on reconstructive surgery.
International Journal of Molecular Medicine. Roč. 40, č. 5 (2017), s. 1323-1334. ISSN 1107-3756. E-ISSN 1791-244X
R&D Projects: GA ČR GA13-20293S; GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) ED1.1.00/02.0109
Grant - others:GA MŠk(CZ) LM2015042
Institutional support: RVO:68378050
Keywords : dermal fibroblasts * myofibroblast * neonatal healing * trandforming growth factor-beta * cleft
OECD category: Cell biology
Impact factor: 2.784, year: 2017 ; AIS: 0.527, rok: 2017
DOI: https://doi.org/10.3892/ijmm.2017.3128
Permanent Link: http://hdl.handle.net/11104/0282006