Search results
- 1.0189173 - UMCH-V 20033128 RIV US eng J - Journal Article
Skálová, Tereza - Hašek, Jindřich - Dohnálek, Jan - Petroková, Hana - Buchtelová, Eva - Dušková, Jarmila - Souček, Milan - Majer, Pavel - Kondrová, Taťána - Konvalinka, Jan
An ethylenamine inhibitor binds tightly to both wild type and mutant HIV-1 proteases. Structure and energy study.
Journal of Medicinal Chemistry. Roč. 46, č. 9 (2003), s. 1636-1644. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA AV ČR IAA4050811; GA AV ČR KJB4050312; GA ČR GV203/98/K023; GA ČR GA204/00/P091; GA ČR GA203/00/D117; GA MZd NI6339
Institutional research plan: CEZ:AV0Z4050913; CEZ:AV0Z4055905
Keywords : mutant HIV-1 protease * ethylenamine inhibitor * structure
Subject RIV: CD - Macromolecular Chemistry
Impact factor: 4.820, year: 2003
Permanent Link: http://hdl.handle.net/11104/0085014 - 2.0188952 - UMCH-V 20023367 RIV US eng J - Journal Article
Dohnálek, Jan - Hašek, Jindřich - Dušková, Jarmila - Petroková, Hana - Hradilek, Martin - Souček, Milan - Konvalinka, Jan - Brynda, Jiří - Sedláček, Juraj - Fábry, Milan
Hydroxyethylamine isostere of an HIV-1 protease inhibitor prefers its amine to the hydroxy group in binding to catalytic aspartates. A synchrotron study of HIV-1 protease in complex with a peptidomimetic inhibitor.
Journal of Medicinal Chemistry. Roč. 45, č. 7 (2002), s. 1432-1438. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA AV ČR IAA4050811; GA ČR GA203/97/P031; GA ČR GV203/98/K023; GA ČR GA203/00/D117; GA ČR GA204/00/P091
Institutional research plan: CEZ:AV0Z4050913
Keywords : HIV-1 protease * hydroxyethylamine-containing inhibitor * aspartate
Subject RIV: CE - Biochemistry
Impact factor: 4.566, year: 2002
Permanent Link: http://hdl.handle.net/11104/0084819