Search results
- 1.0583406 - ÚOCHB 2025 RIV US eng J - Journal Article
Chalupnik, P. - Marek, Aleš - Hovah, M. E. L. - Pickering, D. S. - Temperini, P. - Donbosco, S. - Szymanska, E. - Johansen, T. N.
Tritium and deuterium labelling of a kainate receptor antagonist and evaluation as a radioligand.
Journal of Labelled Compounds and Radiopharmaceuticals. Roč. 67, č. 4 (2024), s. 120-130. ISSN 0362-4803. E-ISSN 1099-1344
Institutional support: RVO:61388963
Keywords : ionotropic glutamate receptors * quinoxaline-2,3-diones * tritium labelling
Impact factor: 1.8, year: 2022
Method of publishing: Open access
https://doi.org/10.1002/jlcr.4087
Permanent Link: https://hdl.handle.net/11104/0351364 - 2.0583159 - ÚOCHB 2025 RIV US eng J - Journal Article
Kriegelstein, Michal - Nováková, Gabriela - Marek, Aleš
Synthesis of [3H]Org24598 using in-house prepared [3H]MeI.
Journal of Labelled Compounds and Radiopharmaceuticals. Roč. 67, č. 3 (2024), s. 91-103. ISSN 0362-4803. E-ISSN 1099-1344
Institutional support: RVO:61388963
Keywords : [H-3]fluoxetine * [H-3]methylation * [H-3]methyl iodide preparation * [H-3]Org24598 * [H-3]thioanisol * COware gas reactor * GlyT1 inhibitor
Impact factor: 1.8, year: 2022
Method of publishing: Limited access
https://doi.org/10.1002/jlcr.4084
Permanent Link: https://hdl.handle.net/11104/0351151 - 3.0561240 - ÚOCHB 2023 RIV GB eng J - Journal Article
Brož, Břetislav - Tureček, F. - Marek, Aleš
Low-scale syringe-made synthesis of 15N-labeled oligonucleotides.
Journal of Labelled Compounds and Radiopharmaceuticals. Roč. 65, č. 12 (2022), s. 309-314. ISSN 0362-4803. E-ISSN 1099-1344
R&D Projects: GA MŠMT(CZ) LTAUSA19094
Institutional support: RVO:61388963
Keywords : 15N-labeled oligonucleotides * low-scale * phosphoramidite synthesis * syringe-made codon synthesis
OECD category: Analytical chemistry
Impact factor: 1.8, year: 2022
Method of publishing: Limited access
https://doi.org/10.1002/jlcr.4000
Permanent Link: https://hdl.handle.net/11104/0333924 - 4.0559559 - ÚOCHB 2023 RIV GB eng J - Journal Article
Kriegelstein, Michal - Marek, Aleš
Synthesis of N-acetyl-L-aspartyl-L-glutamic acid, [3H]NAAG.
Journal of Labelled Compounds and Radiopharmaceuticals. Roč. 65, č. 9 (2022), s. 244-253. ISSN 0362-4803. E-ISSN 1099-1344
Institutional support: RVO:61388963
Keywords : [2H]Glu * [3H]Glu * [3H]NAAG * labeled amino acid * microscale synthesis * tritium labeling
OECD category: Analytical chemistry
Impact factor: 1.8, year: 2022
Method of publishing: Limited access
https://doi.org/10.1002/jlcr.3991
Permanent Link: https://hdl.handle.net/11104/0332825 - 5.0552858 - ÚOCHB 2023 RIV GB eng J - Journal Article
Yongsong, T. - Brož, Břetislav - Tureček, F. - Marek, Aleš
Tritium hydrogen-isotope exchange with electron-poor tertiary benzenesulfonamide moiety, application in late-stage labeling of T0901317.
Journal of Labelled Compounds and Radiopharmaceuticals. Roč. 65, č. 2 (2022), s. 36-44. ISSN 0362-4803. E-ISSN 1099-1344
Institutional support: RVO:61388963
Keywords : catalyst * D2 vs. T2 reactivity * hydrogen isotope exchange * iridium * late-stage-labeling * T0901317 * tetrafluoroethylsulfonamides * tertiary benzenesulfonamides
OECD category: Analytical chemistry
Impact factor: 1.8, year: 2022
Method of publishing: Limited access
https://doi.org/10.1002/jlcr.3958
Permanent Link: http://hdl.handle.net/11104/0327951 - 6.0546208 - ÚOCHB 2022 RIV GB eng J - Journal Article
Kriegelstein, Michal - Hroch, M. - Marek, Aleš
Synthesis of [13C6]-ibrutinib.
Journal of Labelled Compounds and Radiopharmaceuticals. Roč. 64, č. 13 (2021), s. 500-512. ISSN 0362-4803. E-ISSN 1099-1344
Institutional support: RVO:61388963
Keywords : carbon-13 * cost-effective synthesis * stable isotope labeling * [13C6]-ibrutinib
OECD category: Analytical chemistry
Impact factor: 1.949, year: 2021
Method of publishing: Limited access
https://doi.org/10.1002/jlcr.3944
Permanent Link: http://hdl.handle.net/11104/0322756 - 7.0541447 - ÚOCHB 2022 RIV GB eng J - Journal Article
Griem-Krey, N. - Frolund, B. - Marek, Aleš - Wellendorph, P.
Radiolabeled HOCPCA as a highly useful tool in drug discovery and pharmacology.
Journal of Labelled Compounds and Radiopharmaceuticals. Roč. 64, č. 2 (2021), s. 77-81. ISSN 0362-4803. E-ISSN 1099-1344
Institutional support: RVO:61388963
Keywords : GHB high-affinity binding sites * MCT1 uptake * radioligand binding * selective GHB ligand
OECD category: Analytical chemistry
Impact factor: 1.949, year: 2021
Method of publishing: Limited access
https://doi.org/10.1002/jlcr.3870
Permanent Link: http://hdl.handle.net/11104/0318999 - 8.0541244 - ÚOCHB 2022 RIV GB eng J - Journal Article
Pražienková, Veronika - Marek, Aleš - Maletínská, Lenka
Iodination of CART(61-102) peptide: Preserved binding and anorexigenic activity in mice.
Journal of Labelled Compounds and Radiopharmaceuticals. Roč. 64, č. 2 (2021), s. 61-63. ISSN 0362-4803. E-ISSN 1099-1344
Institutional support: RVO:61388963
Keywords : CART peptide * PC12 cells * competitive binding experiments * food intake
OECD category: Biochemistry and molecular biology
Impact factor: 1.949, year: 2021
Method of publishing: Limited access
https://doi.org/10.1002/jlcr.3871
Permanent Link: http://hdl.handle.net/11104/0318832 - 9.0533542 - ÚOCHB 2021 RIV GB eng J - Journal Article
Jiráček, Jiří - Žáková, Lenka - Marek, Aleš
Radiolabeled hormones in insulin research, a minireview.
Journal of Labelled Compounds and Radiopharmaceuticals. Roč. 63, č. 14 (2020), s. 576-581. ISSN 0362-4803. E-ISSN 1099-1344
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA ČR(CZ) GA19-14069S
Institutional support: RVO:61388963
Keywords : assay * binding * hormone * IGF * insulin * radiolabeling * receptor
OECD category: Biochemistry and molecular biology
Impact factor: 1.921, year: 2020
Method of publishing: Limited access
https://doi.org/10.1002/jlcr.3881
Permanent Link: http://hdl.handle.net/11104/0312368 - 10.0510965 - ÚOCHB 2020 RIV GB eng J - Journal Article
Brož, Břetislav - Marek, Aleš
Tritiodefluorination of alkyl C─F groups.
Journal of Labelled Compounds and Radiopharmaceuticals. Roč. 62, č. 11 (2019), s. 743-750. ISSN 0362-4803. E-ISSN 1099-1344
Institutional support: RVO:61388963
Keywords : C-F activation * deuterium labeled alkane * deuterodefluorination * frustrated Lewis pairs * hydrogen activation * non-metallic reagent * tritiodefluorination * tritium labeled alkane * ultra-mild reaction conditions * very low tritium pressure
OECD category: Analytical chemistry
Impact factor: 1.809, year: 2019
Method of publishing: Limited access
https://onlinelibrary.wiley.com/doi/abs/10.1002/jlcr.3782
Permanent Link: http://hdl.handle.net/11104/0301318