Search results
- 1.0579447 - ÚOCHB 2025 RIV GB eng J - Journal Article
Misehe, Mbilo - Šála, Michal - Matoušová, Marika - Hercík, Kamil - Kocek, Hugo - Chalupská, Dominika - Chaloupecká, Ema - Hájek, Miroslav - Bouřa, Evžen - Mertlíková-Kaiserová, Helena - Nencka, Radim
Design, synthesis and evaluation of novel thieno[2,3d]pyrimidine derivatives as potent and specific RIPK2 inhibitors.
Bioorganic & Medicinal Chemistry. Roč. 97, January (2024), č. článku 129567. ISSN 0968-0896. E-ISSN 1464-3391
R&D Projects: GA MZd(CZ) NU20-05-00472; GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Keywords : kinase inhibitor * thieno [2,3d] pyrimidine derivative * receptor-interacting protein kinase 2 * RIPK2 * NOD
Impact factor: 3.5, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.bmcl.2023.129567
Permanent Link: https://hdl.handle.net/11104/0348249File Download Size Commentary Version Access 10.1016j.bmcl.2023.129567.pdf 0 1.6 MB Publisher’s postprint open-access - 2.0577921 - ÚOCHB 2024 RIV GB eng J - Journal Article
Kraina, Pavel - Česnek, Michal - Tloušťová, Eva - Mertlíková-Kaiserová, Helena - Fulton, C. J. - Davidson, E. K. - Smith, B. P. - Watts, V. J. - Janeba, Zlatko
Discovery of a potent and selective human AC2 inhibitor based on 7-deazapurine analogues of adefovir.
Bioorganic & Medicinal Chemistry. Roč. 95, November (2023), č. článku 117508. ISSN 0968-0896. E-ISSN 1464-3391
R&D Projects: GA MŠMT LTAUSA18086
Institutional support: RVO:61388963
Keywords : acyclic nucleoside phosphonates * adefovir * 7-deazapurine * prodrugs * adenylate cyclase
OECD category: Organic chemistry
Impact factor: 3.5, year: 2022
Method of publishing: Limited access
https://doi.org/10.1016/j.bmc.2023.117508
Permanent Link: https://hdl.handle.net/11104/0346999 - 3.0563244 - BFÚ 2023 RIV GB eng J - Journal Article
Figueiredo, J. - Carreira-Barral, I. - Quesada, R. - Mergny, Jean-Louis - Cruz, A.
Synthesis and evaluation of 2,9-disubstituted-1,10-phenanthroline derivatives as G-quadruplex binders.
Bioorganic & Medicinal Chemistry. Roč. 73, NOV 1 2022 (2022), č. článku 116971. ISSN 0968-0896. E-ISSN 1464-3391
R&D Projects: GA MŠMT EF15_003/0000477
Institutional support: RVO:68081707
Keywords : G-quadruplex structures * derivatives * Biophysical evaluation * In vitro studies * 2 * 9-disubstituted-1 * 10-phenanthroline
OECD category: Biochemistry and molecular biology
Impact factor: 3.5, year: 2022
Method of publishing: Open access
https://reader.elsevier.com/reader/sd/pii/S0968089622003649?token=A4EAFEEB1A2D211C650C572D440F273643EE887CF8238E8B72F14E24D6A6E20A00CA5CE417490443521225405C2455A0&originRegion=eu-west-1&originCreation=20221108091428
Permanent Link: https://hdl.handle.net/11104/0340610 - 4.0556554 - ÚOCHB 2023 RIV GB eng J - Journal Article
Chaturvedi, Ritu - Long, E. C.
Mechanistic studies of dinucleotide and oligonucleotide model cyclobutane pyrimidine dimer (CPD) DNA lesions under alkaline conditions.
Bioorganic & Medicinal Chemistry. Roč. 54, January (2022), č. článku 116499. ISSN 0968-0896. E-ISSN 1464-3391
Institutional support: RVO:61388963
Keywords : DNA damage * cyclobutane pyrimidine dimer * alkaline reactivity * hemiaminal * DNA strand break
OECD category: Analytical chemistry
Impact factor: 3.5, year: 2022
Method of publishing: Limited access
https://doi.org/10.1016/j.bmc.2021.116499
Permanent Link: http://hdl.handle.net/11104/0331080 - 5.0552686 - ÚOCHB 2023 RIV GB eng J - Journal Article
Lášek, Tomáš - Petrová, Magdalena - Markusová Kóšiová, Ivana - Šimák, Ondřej - Buděšínský, Miloš - Kozák, Jaroslav - Snášel, Jan - Vavřina, Zdeněk - Birkuš, Gabriel - Rosenberg, Ivan - Páv, Ondřej
5′-Phosphonate modified oligoadenylates as potent activators of human RNase L.
Bioorganic & Medicinal Chemistry. Roč. 56, Feb 15 (2022), č. článku 116632. ISSN 0968-0896. E-ISSN 1464-3391
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : RNase L * Oligoadenylate * Phosphonate oligonucleotide * OAS-RNase L pathway * 2-5A
OECD category: Biochemistry and molecular biology
Impact factor: 3.5, year: 2022
Method of publishing: Limited access
https://doi.org/10.1016/j.bmc.2022.116632
Permanent Link: http://hdl.handle.net/11104/0327809 - 6.0545890 - ÚEB 2022 RIV GB eng J - Journal Article
Maková, B. - Mik, V. - Lišková, B. - Gonzalez, G. - Vítek, D. - Medvedíková, M. - Monfort, B. - Ručilová, V. - Kadlecová, A. - Khirsariya, P. - Gándara Barreiro, Z. - Havlíček, Libor - Zatloukal, M. - Soural, M. - Paruch, K. - D'Autréaux, B. - Hajdúch, M. - Strnad, M. - Voller, Jiří
Cytoprotective activities of kinetin purine isosteres.
Bioorganic & Medicinal Chemistry. Roč. 33, MAR 1 (2021), č. článku 115993. ISSN 0968-0896. E-ISSN 1464-3391
Institutional support: RVO:61389030
Keywords : bioisostery – Friedreich́s ataxia * Cytokinin * Kinetin * Mitoprotection – familial dysautonomia * Neuroprotection
OECD category: Pharmacology and pharmacy
Impact factor: 3.461, year: 2021
Method of publishing: Open access
http://doi.org/10.1016/j.bmc.2021.115993
Permanent Link: http://hdl.handle.net/11104/0322516File Download Size Commentary Version Access 2021_Makova_BIOORGANIC & MEDICINAL CHEMISTRY_115993.pdf 1 1.1 MB Other open-access - 7.0538783 - ÚOCHB 2022 RIV GB eng J - Journal Article
Pomeislová, Alice - Otmar, Miroslav - Rubešová, Petra - Benýšek, Jakub - Matoušová, Marika - Mertlíková-Kaiserová, Helena - Pohl, Radek - Poštová Slavětínská, Lenka - Pomeisl, Karel - Krečmerová, Marcela
1,2,4-Thiadiazole acyclic nucleoside phosphonates as inhibitors of cysteine dependent enzymes cathepsin K and GSK-3β.
Bioorganic & Medicinal Chemistry. Roč. 32, Feb 15 (2021), č. článku 115998. ISSN 0968-0896. E-ISSN 1464-3391
R&D Projects: GA MŠMT(CZ) LM2018133; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963 ; RVO:61389013 ; RVO:68378271
Keywords : thiadiazoles * 5-amino-1,2,4-thiadiazol-3-(2H)-one * acyclic nucleoside phosphonates * epigenetic * cathepsin K * glycogen synthase kinase 3β
OECD category: Biochemistry and molecular biology; Polymer science (UMCH-V); Organic chemistry (FZU-D)
Impact factor: 3.461, year: 2021
Method of publishing: Limited access
https://doi.org/10.1016/j.bmc.2021.115998
Permanent Link: http://hdl.handle.net/11104/0316958 - 8.0522874 - ÚMG 2020 RIV GB eng J - Journal Article
Zima, V. - Albinana, C. B. - Rojíková, K. - Pokorná, J. - Pachl, P. - Řezáčová, Pavlína - Hudlický, J. - Navrátil, V. - Majer, P. - Konvalinka, J. - Kožíšek, M. - Machara, A.
Investigation of flexibility of neuraminidase 150-loop using tamiflu derivatives in influenza A viruses H1N1 and H5N1.
Bioorganic & Medicinal Chemistry. Roč. 27, č. 13 (2019), s. 2935-2947. ISSN 0968-0896. E-ISSN 1464-3391
Institutional support: RVO:68378050
Keywords : Influenza neuraminidase * Oseltamivir * Click chemistry * Crystal structure
OECD category: Cell biology
Impact factor: 3.073, year: 2019
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0968089619305358?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0307288 - 9.0522677 - ÚEB 2020 RIV GB eng J - Journal Article
Matušková, Vlasta - Zatloukal, M. - Voller, Jiří - Grúz, Jiří - Pěkná, Z. - Briestenská, K. - Mistríková, J. - Spíchal, L. - Doležal, Karel - Strnad, Miroslav
New aromatic 6-substituted 2′-deoxy-9-(β)-D-ribofuranosylpurine derivatives as potential plant growth regulators.
Bioorganic & Medicinal Chemistry. Roč. 28, č. 2 (2020), č. článku 115230. ISSN 0968-0896. E-ISSN 1464-3391
R&D Projects: GA MŠMT(CZ) EF16_019/0000827
Institutional support: RVO:61389030
Keywords : 2′-Deoxyribosides * Antioxidative capacity * Antiviral testing * Aromatic cytokinins * Plant growth regulator * Purine derivatives
OECD category: Biochemistry and molecular biology
Impact factor: 3.641, year: 2020
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0968089619317304
Permanent Link: http://hdl.handle.net/11104/0307127File Download Size Commentary Version Access 2020_Matuskova_BIOORGANIC & MEDICINAL CHEMISTRY_115230.pdf 1 959.4 KB Other open-access - 10.0511157 - FZÚ 2020 RIV GB eng J - Journal Article
Pomeisl, Karel - Lamatová, N. - Šolínová, V. - Pohl, R. - Brabcová, J. - Kašička, V. - Krečmerová, M.
Enantioselective resolution of side-chain modified gem-difluorinated alcohols catalysed by Candida antarctica lipase B and monitored by capillary electrophoresis.
Bioorganic & Medicinal Chemistry. Roč. 27, č. 7 (2019), s. 1246-1253. ISSN 0968-0896. E-ISSN 1464-3391
Institutional support: RVO:68378271
Keywords : acyclic nucleoside phosphonates * candida antarctica lipase * capillary electrophoresis * enantioselective resolution * enzyme catalysis
OECD category: Biochemistry and molecular biology
Impact factor: 3.073, year: 2019
Method of publishing: Limited access
https://doi.org/10.1016/j.bmc.2019.02.022
Permanent Link: http://hdl.handle.net/11104/0301493