Search results

  1. 1.
    0586126 - MBÚ 2025 RIV NL eng J - Journal Article
    Weber, P. - Bojarová, Pavla - Brouzdová, Jitka - Křen, Vladimír - Kulik, Natalia - Stütz, A.E. - Thonhofer, M. - Wrodnigg, T.M.
    Diaminocyclopentane – l-Lysine Adducts: Potent and selective inhibitors of human O-GlcNAcase.
    Bioorganic Chemistry. Roč. 148, July 2024 (2024), č. článku 107452. ISSN 0045-2068. E-ISSN 1090-2120
    R&D Projects: GA ČR(CZ) GF21-01948L; GA MŠMT(CZ) EH22_008/0004597
    Research Infrastructure: e-INFRA CZ - 90140; CERIT-SC - 90085; CESNET II - 90042
    Institutional support: RVO:61388971
    Keywords : Glycosidase * Inhibition * Inhibition * O-GlcNAcase * Hexosaminidase * Diaminocyclopentane * Tau protein * Alzheimer’s disease
    OECD category: Biochemistry and molecular biology
    Impact factor: 5.1, year: 2022
    Method of publishing: Open access
    https://www.sciencedirect.com/science/article/pii/S0045206824003572
    Permanent Link: https://hdl.handle.net/11104/0353722
    FileDownloadSizeCommentaryVersionAccess
    Diaminocyclopentane – l-Lysine Adducts.pdf07.4 MBPublisher’s postprintopen-access
     
     
  2. 2.
    0585706 - ÚOCHB 2025 RIV NL eng J - Journal Article
    Chaloupecká, Ema - Kurfiřt, Martin - Červenková Šťastná, Lucie - Karban, Jindřich - Dračínský, Martin
    Exploring long-range fluorine-carbon J-coupling for conformational analysis of deoxyfluorinated disaccharides: A combined computational and NMR study.
    Bioorganic Chemistry. Roč. 147, June (2024), č. článku 107388. ISSN 0045-2068. E-ISSN 1090-2120
    R&D Projects: GA ČR(CZ) GA23-05146S
    Institutional support: RVO:61388963 ; RVO:67985858
    Keywords : saccharides * NMR spectroscopy * conformation * DFT calculations * fluorine
    OECD category: Organic chemistry (UCHP-M)
    Impact factor: 5.1, year: 2022
    Method of publishing: Limited access
    https://doi.org/10.1016/j.bioorg.2024.107388
    Permanent Link: https://hdl.handle.net/11104/0353409
    FileDownloadSizeCommentaryVersionAccess
    1-s2.0-S0045206824002931-main.pdf03.6 MBPublisher’s postprintrequire
     
     
  3. 3.
    0585671 - ÚCHP 2025 RIV NL eng J - Journal Article
    Kurfiřt, Martin - Hamala, Vojtěch - Beránek, J. - Červenková Šťastná, Lucie - Červený, Jakub - Dračínský, Martin - Bernášková, Jana - Spiwok, V. - Bosáková, Z. - Bojarová, Pavla - Karban, Jindřich
    Synthesis and unexpected binding of monofluorinated N,Nʹ-diacetylchitobiose and LacdiNAc to wheat germ agglutinin.
    Bioorganic Chemistry. Roč. 147, June 2024 (2024), č. článku 107395. ISSN 0045-2068. E-ISSN 1090-2120
    R&D Projects: GA ČR(CZ) GA23-05146S; GA MŠMT(CZ) LTC20052; GA MŠMT(CZ) LM2023055
    Grant - others:MEYS(XE) CA18103
    Research Infrastructure: e-INFRA CZ II - 90254
    Institutional support: RVO:67985858 ; RVO:61388971 ; RVO:61388963
    Keywords : fluorinated carbohydrates * chemical synthesis * wheat germ agglutinin * ELLA
    OECD category: Organic chemistry; Organic chemistry (UOCHB-X); Organic chemistry (MBU-M)
    Impact factor: 5.1, year: 2022
    Method of publishing: Open access with time embargo
    Permanent Link: https://hdl.handle.net/11104/0353359
    FileDownloadSizeCommentaryVersionAccess
    0585671.pdf04.6 MBAuthor’s postprintrequire
     
     
  4. 4.
    0585278 - MBÚ 2025 RIV NL eng J - Journal Article
    Vrbata, David - Červený, Jakub - Kulik, Natalia - Hovorková, Michaela - Balogová, Soňa - Vlachová, Miluše - Pelantová, Helena - Křen, Vladimír - Bojarová, Pavla
    Glycomimetic inhibitors of tandem-repeat galectins: Simple and efficient.
    Bioorganic Chemistry. Roč. 145, April 24 (2024), č. článku 107231. ISSN 0045-2068. E-ISSN 1090-2120
    R&D Projects: GA ČR(CZ) GA22-00262S; GA MŠMT(CZ) LUC23148
    Research Infrastructure: e-INFRA CZ II - 90254
    Institutional support: RVO:61388971
    Keywords : carbohydrate-recognition * domain * lectin * oligosaccharide * optimization * expression * crystal * docking * Glycomimetic * Molecular modeling * Tandem-repeat galectin * Structure-affinity relationship * Thiodigalactoside
    OECD category: Biochemistry and molecular biology
    Impact factor: 5.1, year: 2022
    Method of publishing: Limited access
    https://www.sciencedirect.com/science/article/pii/S0045206824001366?via%3Dihub
    Permanent Link: https://hdl.handle.net/11104/0353049
     
     
  5. 5.
    0583286 - ÚOCHB 2025 RIV NL eng J - Journal Article
    Khaleel, E. F. - Sabt, A. - Korycka-Machala, M. - Badi, R. M. - Son, N. T. - Ha, N. X. - Hamissa, Mohamed Farouk - Elsawi, A. E. - Elkaeed, E. B. - Dziadek, B. - Eldehna, W. M. - Dziadek, J.
    Identification of new anti-mycobacterial agents based on quinoline-isatin hybrids targeting enoyl acyl carrier protein reductase (InhA).
    Bioorganic Chemistry. Roč. 144, March (2024), č. článku 107138. ISSN 0045-2068. E-ISSN 1090-2120
    Institutional support: RVO:61388963
    Keywords : biological activities * mycobacterium tuberculosis * InhA inhibitors * molecular docking * molecular dynamics Simulation
    Impact factor: 5.1, year: 2022
    Method of publishing: Limited access
    https://doi.org/10.1016/j.bioorg.2024.107138
    Permanent Link: https://hdl.handle.net/11104/0351289
     
     
  6. 6.
    0577013 - MBÚ 2024 RIV NL eng J - Journal Article
    Weber, P. - Mészáros, Zuzana - Bojarová, Pavla - Ebner, M. - Fischer, R. - Křen, Vladimír - Kulik, Natalia - Müller, P. - Vlachová, Miluše - Slámová, Kristýna - Stütz, A.E. - Thonhofer, M. - Torvisco, A. - Wrodnigg, T. M. - Wolfsgruber, A.
    Highly functionalized diaminocyclopentanes: A new route to potent and selective inhibitors of human O-GlcNAcase.
    Bioorganic Chemistry. Roč. 140, November 2023 (2023), č. článku 106819. ISSN 0045-2068. E-ISSN 1090-2120
    R&D Projects: GA ČR(CZ) GF21-01948L
    Institutional support: RVO:61388971
    Keywords : Glycosidase inhibition * O-GlcNAcase * Diaminocyclopentane * Alzheimer's disease
    OECD category: Biochemistry and molecular biology
    Impact factor: 5.1, year: 2022
    Method of publishing: Open access
    https://www.sciencedirect.com/science/article/pii/S0045206823004807?via%3Dihub
    Permanent Link: https://hdl.handle.net/11104/0347328
     
     
  7. 7.
    0567424 - MBÚ 2024 RIV NL eng J - Journal Article
    Hovorková, Michaela - Červený, Jakub - Bumba, Ladislav - Pelantová, Helena - Cvačka, Josef - Křen, Vladimír - Renaudet, O. - Goyard, D. - Bojarová, Pavla
    Advanced high-affinity glycoconjugate ligands of galectins.
    Bioorganic Chemistry. Roč. 131, February (2023), č. článku 106279. ISSN 0045-2068. E-ISSN 1090-2120
    R&D Projects: GA ČR(CZ) GA22-00317S; GA MŠMT(CZ) LTC19038
    Institutional support: RVO:61388971 ; RVO:61388963
    Keywords : Biolayer interferometry * Carbohydrate * Click chemistry * Galectin * Glycoconjugate * Multivalency * Transglycosylation
    OECD category: Biochemistry and molecular biology; Analytical chemistry (UOCHB-X)
    Impact factor: 5.1, year: 2022
    Method of publishing: Limited access
    https://www.sciencedirect.com/science/article/pii/S004520682200685X?via%3Dihub
    Permanent Link: https://hdl.handle.net/11104/0342596
     
     
  8. 8.
    0561914 - FZÚ 2023 RIV US eng J - Journal Article
    Gholivand, K. - Faraghi, M. - Fallah, N. - Babaei, A. - Pirastehfar, F. - Dušek, Michal - Eigner, Václav - Salimi, F.
    Therapeutic potential of phospho-thiadiazole derivatives as anti-glioblastoma agents: synthesis, biological assessment and computational study.
    Bioorganic Chemistry. Roč. 129, Dec. (2022), č. článku 106123. ISSN 0045-2068. E-ISSN 1090-2120
    R&D Projects: GA MŠMT(CZ) EF16_019/0000760
    Grant - others:OP VVV - SOLID21(XE) CZ.02.1.01/0.0/0.0/16_019/0000760
    Institutional support: RVO:68378271
    Keywords : phospho thiadiazole * anticancer activity * X-ray structure * DFT calculation * molecular docking
    OECD category: Condensed matter physics (including formerly solid state physics, supercond.)
    Impact factor: 5.1, year: 2022
    Method of publishing: Limited access
    https://doi.org/10.1016/j.bioorg.2022.106123
    Permanent Link: https://hdl.handle.net/11104/0334335
     
     
  9. 9.
    0561212 - FZÚ 2023 RIV US eng J - Journal Article
    Nepovímová, E. - Svobodová, L. - Doležal, R. - Rostohar, Danijela … Total 30 authors
    Tacrine – benzothiazoles: novel class of potential multitarget anti-Alzheimer's drugs dealing with cholinergic, amyloid and mitochondrial systems.
    Bioorganic Chemistry. Roč. 107, Feb (2021), č. článku 104596. ISSN 0045-2068. E-ISSN 1090-2120
    EU Projects: European Commission(XE) 654148 - LASERLAB-EUROPE
    Institutional support: RVO:68378271
    Keywords : Alzheimer's disease * tacrine * benzothiazole * acetylcholinesterase Inhibitors * amyloid beta * ABAD * MTDLs
    OECD category: Optics (including laser optics and quantum optics)
    Impact factor: 5.307, year: 2021
    Method of publishing: Limited access
    https://doi.org/10.1016/j.bioorg.2020.104596
    Permanent Link: https://hdl.handle.net/11104/0333898
     
     
  10. 10.
    0559646 - MBÚ 2023 RIV US eng J - Journal Article
    Velueta-Viveros, M. - Martinez-Bailen, M. - Puerta, A. - Romero-Hernandez, L. L. - Křen, Vladimír - Merino-Montiel, P. - Montiel-Smith, S. - Fernandes, Miguel X. - Moreno-Vargas, Antonio J. - Padron, Jose M. - Lopez, O. - Fernandez-Bolanos, J. G.
    Carbohydrate-derived bicyclic selenazolines as new dual inhibitors (cholinesterases/OGA) against Alzheimer's disease.
    Bioorganic Chemistry. Roč. 127, OCT 2022 (2022), č. článku 105983. ISSN 0045-2068. E-ISSN 1090-2120
    R&D Projects: GA ČR(CZ) GF21-01948L
    Institutional support: RVO:61388971
    Keywords : Selenazolines * AChE * BuChE * oga * Docking simulations
    OECD category: Biochemistry and molecular biology
    Impact factor: 5.1, year: 2022
    Method of publishing: Limited access
    https://www.sciencedirect.com/science/article/pii/S0045206822003881?via%3Dihub
    Permanent Link: https://hdl.handle.net/11104/0333195
     
     

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