Search results

  1. 1.
    0580603 - BC 2024 RIV US eng J - Journal Article
    Taleva, Gergana - Husová, Michaela - Panicucci, Brian - Hierro-Yap, Carolina - Pineda, E. - Biran, M. - Moos, Martin - Šimek, Petr - Butter, F. - Bringaud, F. - Zíková, Alena
    Mitochondrion of the Trypanosoma brucei long slender bloodstream form is capable of ATP production by substrate-level phosphorylation.
    PLoS Pathogens. Roč. 19, č. 10 (2023), č. článku e1011699. ISSN 1553-7366. E-ISSN 1553-7374
    R&D Projects: GA ČR(CZ) GA20-14409S
    EU Projects: European Commission(XE) 101044951 - MitoSignal
    Institutional support: RVO:60077344
    Keywords : inducible expression system * succinate coa-transferase * trypanocidal action * lipid biosynthesis * acetate * fractionation * complex
    OECD category: Cell biology
    Impact factor: 6.7, year: 2022
    Method of publishing: Open access
    https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1011699
    Permanent Link: https://hdl.handle.net/11104/0349377
     
     
  2. 2.
    0579778 - BC 2024 RIV NL eng J - Journal Article
    Lukeš, Julius - Speijer, D. - Zíková, Alena - Alfonzo, J. D. - Hashimi, Hassan - Field, Mark Christian
    Trypanosomes as a magnifying glass for cell and molecular biology.
    Trends in Parasitology. Roč. 39, č. 11 (2023), s. 902-912. ISSN 1471-4922. E-ISSN 1471-5007
    R&D Projects: GA ČR(CZ) GA23-07674S; GA ČR(CZ) GX23-06479X; GA ČR(CZ) GA20-14409S
    EU Projects: European Commission(XE) 101044951 - MitoSignal; Wellcome Trust(GB) 204697/Z/16/Z
    Grant - others:Gordon and Betty Moore Foundation(US) GBMF9354
    Program: Science
    Institutional support: RVO:60077344
    Keywords : variant surface glycoprotein * double-stranded-rna * alternative oxidase * sleeping sickness * brucei * mitochondria * import * localization * degradation * peroxisomes
    OECD category: Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology
    Impact factor: 9.6, year: 2022
    Method of publishing: Limited access
    https://www.sciencedirect.com/science/article/pii/S1471492223001952?via%3Dihub
    Permanent Link: https://hdl.handle.net/11104/0348589
    FileDownloadSizeCommentaryVersionAccess
    Lukes_2023_TrendsinParasitol.pdf01.4 MBAuthor’s postprintopen-access
     
     
  3. 3.
    0574463 - BC 2024 RIV US eng J - Journal Article
    Valach, M. - Benz, Corinna - Aguilar, L.C. - Gahura, Ondřej - Faktorová, Drahomíra - Zíková, Alena - Oeffinger, M. - Burger, G. - Gray, M.W. - Lukeš, Julius
    Miniature RNAs are embedded in an exceptionally protein-rich mitoribosome via an elaborate assembly pathway.
    Nucleic Acids Research. Roč. 51, č. 12 (2023), s. 6443-6460. ISSN 0305-1048. E-ISSN 1362-4962
    R&D Projects: GA ČR(CZ) GX23-06479X; GA ČR(CZ) GJ20-04150Y; GA MŠMT(CZ) EF16_019/0000759
    EU Projects: European Commission(XE) 101044951 - MitoSignal
    Grant - others:Gordon and Betty Moore Foundation(US) GBMF9354
    Institutional support: RVO:60077344
    Keywords : RNAs * protein-rich mitoribosome
    OECD category: Microbiology
    Impact factor: 14.9, year: 2022
    Method of publishing: Open access
    https://academic.oup.com/nar/article/51/12/6443/7173778?login=true
    Permanent Link: https://hdl.handle.net/11104/0344803
    FileDownloadSizeCommentaryVersionAccess
    Valach_2023_NucAcidRes.pdf42.3 MBPublisher’s postprintopen-access
     
     
  4. 4.
    0574448 - BC 2024 RIV US eng J - Journal Article
    Wong, Jonathan - Zíková, Alena - Gahura, Ondřej
    The Ancestral Shape of the Access Proton Path of Mitochondrial ATP Synthases Revealed by a Split Subunit-a.
    Molecular Biology and Evolution. Roč. 40, č. 6 (2023), č. článku msad146. ISSN 0737-4038. E-ISSN 1537-1719
    R&D Projects: GA ČR(CZ) GJ20-04150Y; GA MŠMT(CZ) EF16_019/0000759
    EU Projects: European Commission(XE) 101044951 - MitoSignal
    Institutional support: RVO:60077344
    Keywords : subunit-a * proton translocation * gene fragmentation * proton path * Trypanosoma brucei * mitochondrial ATP synthase
    OECD category: Biochemistry and molecular biology
    Impact factor: 10.7, year: 2022
    Method of publishing: Open access
    https://academic.oup.com/mbe/article/40/6/msad146/7203835?login=true
    Permanent Link: https://hdl.handle.net/11104/0344809
    FileDownloadSizeCommentaryVersionAccess
    Wong_2023_MolBiolEvol.pdf25.7 MBPublisher’s postprintopen-access
     
     
  5. 5.
    0569955 - BTÚ 2023 RIV US eng J - Journal Article
    Arbon, D. - Zeniskova, K. - Subrtova, K. - Mach, J. - Štursa, Jan - Machado, M. - Zahedifard, F. - Leštinová, T. - Hierro Yap, Carolina - Neužil, Jiří - Volf, P. - Ganter, M. - Zoltner, M. - Zíková, Alena - Werner, Lukáš - Suták, R.
    Repurposing of MitoTam: Novel Anti-Cancer Drug Candidate Exhibits Potent Activity against Major Protozoan and Fungal Pathogens.
    Antimicrobial Agents and Chemotherapy. Roč. 66, č. 8 (2022). ISSN 0066-4804. E-ISSN 1098-6596
    R&D Projects: GA MŠMT(CZ) EF16_019/0000759; GA ČR(CZ) GA20-14409S; GA MŠMT(CZ) LM2018129; GA MŠMT(CZ) EF18_046/0016045; GA ČR(CZ) GA20-14409S
    Institutional support: RVO:86652036 ; RVO:60077344
    Keywords : Candida * Cryptococcus * drug * Leishmania
    OECD category: Pharmacology and pharmacy; Cell biology (BC-A)
    Impact factor: 4.9, year: 2022
    Method of publishing: Open access
    https://journals.asm.org/doi/10.1128/aac.00727-22
    Permanent Link: https://hdl.handle.net/11104/0341283
     
     
  6. 6.
    0567779 - BC 2023 RIV GB eng J - Journal Article
    Gahura, Ondřej - Chauhan, Prashant - Zíková, Alena
    Mechanisms and players of mitoribosomal biogenesis revealed in trypanosomatids.
    Trends in Parasitology. Roč. 38, č. 12 (2022), s. 1053-1067. ISSN 1471-4922. E-ISSN 1471-5007
    R&D Projects: GA ČR(CZ) GJ20-04150Y; GA MŠMT(CZ) EF16_019/0000759
    Institutional support: RVO:60077344
    Keywords : assembly factor * biogenesis * mitochondrial ribosomes * mitoribosomes * Trypanosoma
    OECD category: Biochemistry and molecular biology
    Impact factor: 9.6, year: 2022
    Method of publishing: Limited access
    https://www.sciencedirect.com/science/article/pii/S1471492222001878?via%3Dihub
    Permanent Link: https://hdl.handle.net/11104/0339044
     
     
  7. 7.
    0564728 - BC 2023 RIV US eng J - Journal Article
    Zíková, Alena
    Mitochondrial adaptations throughout the Trypanosoma brucei life cycle.
    Journal of Eukaryotic Microbiology. Roč. 69, č. 6 (2022), č. článku e12911. ISSN 1066-5234. E-ISSN 1550-7408
    R&D Projects: GA ČR(CZ) GA20-14409S; GA MŠMT(CZ) EF16_019/0000759; GA ČR(CZ) GA22-34480S
    Institutional support: RVO:60077344
    Keywords : differentiation * metabolism * mitochondria * signaling * Trypanosoma
    OECD category: Cell biology
    Impact factor: 2.2, year: 2022
    Method of publishing: Limited access
    https://onlinelibrary.wiley.com/doi/10.1111/jeu.12911
    Permanent Link: https://hdl.handle.net/11104/0340561
     
     
  8. 8.
    0563879 - MBÚ 2023 RIV DE eng J - Journal Article
    Štěpánek, O. - Čmoková, Adéla - Procházková, Eliška - Grobárová, V. - Černý, J. - Slapničková, Martina - Zíková, Alena - Kolařík, Miroslav - Baszczyňski, O.
    Piperazine-Modified Ketoconazole Derivatives Show Increased Activity against Fungal and Trypanosomatid Pathogens.
    ChemMedChem. Roč. 17, č. 21 (2022), č. článku e202200385. ISSN 1860-7179. E-ISSN 1860-7187
    R&D Projects: GA ČR(CZ) GA19-07707S; GA MZd(CZ) NU21-05-00681; GA MŠMT(CZ) EF16_019/0000759
    Grant - others:AV ČR JFS20ST-127; AV ČR JFS20ST-127
    Program: SEA-Europe JFS; SEA-Europe JFS
    Institutional support: RVO:61388971 ; RVO:61388963 ; RVO:60077344
    Keywords : Ketoconazole * Antifungal agents * Aspergillus * Trypanosoma
    OECD category: Microbiology; Analytical chemistry (UOCHB-X); Organic chemistry (BC-A)
    Impact factor: 3.4, year: 2022
    Method of publishing: Limited access
    https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cmdc.202200385
    Permanent Link: https://hdl.handle.net/11104/0335666
     
     
  9. 9.
    0563704 - BC 2023 RIV GB eng J - Journal Article
    Gahura, Ondřej - Muhleip, A. - Hierro Yap, Carolina - Panicucci, Brian - Jain, Minal - Hollaus, D. - Slapničková, Martina - Zíková, Alena - Amunts, A.
    An ancestral interaction module promotes oligomerization in divergent mitochondrial ATP synthases.
    Nature Communications. Roč. 13, č. 1 (2022), č. článku 5989. E-ISSN 2041-1723
    R&D Projects: GA ČR(CZ) GA18-17529S; GA ČR(CZ) GJ20-04150Y; GA MŠMT(CZ) EF16_019/0000759
    Institutional support: RVO:60077344
    Keywords : Mitochondrial * synthase * lineage
    OECD category: Biochemistry and molecular biology
    Impact factor: 16.6, year: 2022
    Method of publishing: Open access
    https://www.nature.com/articles/s41467-022-33588-z
    Permanent Link: https://hdl.handle.net/11104/0339020
     
     
  10. 10.
    0561246 - ÚOCHB 2023 RIV DE eng J - Journal Article
    Lemke, C. - Jílková, Adéla - Ferber, D. - Braune, A. - On, A. - Johe, P. - Zíková, Alena - Schirmeister, T. - Mareš, Michael - Horn, Martin - Gütschow, M.
    Two Tags in One Probe: Combining Fluorescence- and Biotin-based Detection of the Trypanosomal Cysteine Protease Rhodesain.
    Chemistry - A European Journal. Roč. 28, č. 62 (2022), č. článku e202201636. ISSN 0947-6539. E-ISSN 1521-3765
    R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) EF16_019/0000759
    Institutional support: RVO:61388963 ; RVO:60077344
    Keywords : activity-based probes * affinity chromatography * cysteine proteases * imaging agents * peptidomimetics * rhodesain * size exclusion chromatography
    OECD category: Biochemistry and molecular biology; Microbiology (BC-A)
    Impact factor: 4.3, year: 2022
    Method of publishing: Open access
    https://doi.org/10.1002/chem.202201636
    Permanent Link: https://hdl.handle.net/11104/0333931
     
     

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