Search results
- 1.0482266 - BC 2018 RIV US eng J - Journal Article
Garbe, J.C. - Vrba, Lukáš - Sputova, K. - Fuchs, L. - Novák, Petr - Brothman, A.R. - Jackson, M. - Chin, K. - LaBarge, M.A. - Watts, G. - Futscher, B. W. - Stampfer, M.R.
Immortalization of normal human mammary epithelial cells in two steps by direct targeting of senescence barriers does not require gross genomic alterations.
Cell Cycle. Roč. 13, č. 21 (2014), s. 3423-3435. ISSN 1538-4101. E-ISSN 1551-4005
Institutional support: RVO:60077344
Keywords : genomic instability * human mammary epithelial cells * telomerase
OECD category: Cell biology
Impact factor: 4.565, year: 2014
Permanent Link: http://hdl.handle.net/11104/0277648 - 2.0398564 - BC 2014 US eng J - Journal Article
Vrba, Lukáš - Munoz-Rodriguez, J.L. - Stampfer, M.R. - Futscher, B. W.
miRNA Gene Promoters Are Frequent Targets of Aberrant DNA Methylation in Human Breast Cancer.
PLoS ONE. Roč. 8, č. 1 (2013), e54398. ISSN 1932-6203. E-ISSN 1932-6203
Institutional support: RVO:60077344
Keywords : Tumor-Suppressor * feedback loop * microRNAs
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 3.534, year: 2013
Permanent Link: http://hdl.handle.net/11104/0226034 - 3.0383234 - BC 2013 US eng J - Journal Article
Severson, P.L. - Tokar, E.J. - Vrba, Lukáš - Waalkes, M.P. - Futscher, B. W.
Agglomerates of aberrant DNA methylation are associated with toxicant-induced malignant transformation.
Epigenetics. Roč. 7, č. 11 (2012), s. 1238-1248. ISSN 1559-2294. E-ISSN 1559-2308
Institutional research plan: CEZ:AV0Z50510513
Keywords : agglomerative DNA methylation * H3K27me3 * H3K9me3 * epigenetics
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 4.920, year: 2012
Permanent Link: http://hdl.handle.net/11104/0213237 - 4.0383230 - BC 2013 US eng J - Journal Article
Vrba, Lukáš - Garbe, J. - Stampfer, M.R. - Futscher, B. W.
Epigenetic regulation of normal human mammary cell type-specific miRNAs.
Genome Research. Roč. 21, č. 12 (2011), s. 2026-2037. ISSN 1088-9051. E-ISSN 1549-5469
Institutional research plan: CEZ:AV0Z50510513
Institutional support: RVO:60077344
Keywords : DNA metylation * gene expression * transcription
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 13.608, year: 2011
Permanent Link: http://hdl.handle.net/11104/0213234 - 5.0370369 - BC 2012 RIV US eng J - Journal Article
Vrba, Lukáš - Jensen, T.J. - Garbe, J. - Heimark, R.L. - Cress, A.E. - Dickinson, S. - Stampfer, M.R. - Futscher, B. W.
Role for DNA Methylation in the Regulation of miR-200c and miR-141 Expression in Normal and Cancer Cells.
PLoS ONE. Roč. 5, č. 1 (2010), e8697. ISSN 1932-6203. E-ISSN 1932-6203
Institutional research plan: CEZ:AV0Z50510513
Keywords : GENE-EXPRESSION * HISTONE METHYLTRANSFERASE * E-CADHERIN
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 4.411, year: 2010
Permanent Link: http://hdl.handle.net/11104/0204198 - 6.0321750 - BC 2009 RIV GB eng J - Journal Article
Vrba, Lukáš - Junk, D.J. - Novák, Petr - Futscher, B. W.
P53 induces distinct epigenetic states at its direct target promoters.
[P53 indukuje vazbou v cílových promotorech rozdílné epigenetické stavy.]
BMC Genomics. Roč. 9, - (2008), s. 486. ISSN 1471-2164. E-ISSN 1471-2164
Institutional research plan: CEZ:AV0Z50510513
Keywords : immunoprecipitation * promoter
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 3.926, year: 2008
Permanent Link: http://hdl.handle.net/11104/0170196 - 7.0096853 - BC 2010 RIV CZ eng J - Journal Article
Patzak, J. - Vrba, Lukáš - Matoušek, Jaroslav
New STS molecular markers for assessment of genetic diversity and DNA fingerprinting in hop (Humulus lupulus L.).
[Nové STS molekulové markery pro stanovení genetické diverzity a identifikaci genotypů chmelu (Humulus lupulus L.).]
Genome. Roč. 50, č. 1 (2007), s. 15-25. ISSN 0831-2796. E-ISSN 1480-3321
R&D Projects: GA ČR GA521/03/0072
Institutional research plan: CEZ:AV0Z50510513
Keywords : hop (Humulus lupulus L.) * genetic diversity
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 1.785, year: 2007
Permanent Link: http://hdl.handle.net/11104/0156123 - 8.0078506 - BC 2007 RIV US eng J - Journal Article
Matoušek, Jaroslav - Vrba, Lukáš - Škopek, Josef - Orctová, Lidmila - Pešina, Karel - Heyerick, A. - Baulcombe, D. - De Keukeleire, D.
Sequence analysis of a "true" chalcone synthase (chs_H1) oligofamily from hop (Humulus lupulus L.) and PAP1 activation of chs_H1 in heterologous systems.
[Sekvenční analýza oligorodiny "pravé" chalkonsyntázy (chs_H1) z chmelu (Humulus lupulus L.) a aktivace chs_H1 pomocí PAP1 v heterologních systémech.]
Journal of Agricultural and Food Chemistry. Roč. 54, - (2006), s. 7606-7615. ISSN 0021-8561. E-ISSN 1520-5118
R&D Projects: GA ČR GA521/03/0072; GA ČR(CZ) GP521/06/P323
Institutional research plan: CEZ:AV0Z50510513
Keywords : cDNA library * Humulus lupulus L.
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 2.322, year: 2006
Permanent Link: http://hdl.handle.net/11104/0143593 - 9.0076399 - BC 2007 RIV NL eng J - Journal Article
Kocábek, Tomáš - Řepková, J. - Dudová, M. - Hoyerová, Klára - Vrba, Lukáš
Isolation and characterization of a novel semi-lethal Arabidopsis thaliana mutant of gene for pentatricopeptide (PPR) repeat-containing protein.
[Izolace a charakterizace nové semiletální mutace u Arabidopsis thaliana v genu pro protein obsahující PPR.]
Genetica. Roč. 128, - (2006), s. 395-407. ISSN 0016-6707. E-ISSN 1573-6857
R&D Projects: GA ČR GA521/00/D036; GA ČR(CZ) GD204/05/H505; GA AV ČR KJB600510503
Institutional research plan: CEZ:AV0Z50510513
Keywords : Arabidopsis thaliana * gene manipulation
Subject RIV: EB - Genetics ; Molecular Biology
Impact factor: 1.492, year: 2006
Permanent Link: http://hdl.handle.net/11104/0143507