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- 1.0576137 - ÚOCHB 2024 RIV US eng J - Journal Article
Inniss, N. L. - Kozic, Ján - Li, F. - Rosas-Lemus, M. - Minasov, G. - Rybáček, Jiří - Zhu, Y. - Pohl, Radek - Shuvalova, L. - Rulíšek, Lubomír - Brunzelle, J. S. - Bednárová, Lucie - Štefek, Milan - Kormaník, Ján Michael - Andris, Erik - Šebestík, Jaroslav - Li, A. S. M. - Brown, P. J. - Schmitz, U. - Saikatendu, K. - Chang, E. - Nencka, Radim - Vedadi, M. - Satchell, K. J. F.
Discovery of a Druggable, Cryptic Pocket in SARS-CoV-2 nsp16 Using Allosteric Inhibitors.
ACS Infectious Diseases. Roč. 9, č. 10 (2023), s. 1918-1931. ISSN 2373-8227
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA MZd(CZ) NU20-05-00472
Institutional support: RVO:61388963
Keywords : coronavirus * NSP16 methyltransferase * covalent inhibitors * structural biology * antiviral
OECD category: Virology
Impact factor: 5.3, year: 2022
Method of publishing: Limited access
https://doi.org/10.1021/acsinfecdis.3c00203
Permanent Link: https://hdl.handle.net/11104/0345731 - 2.0574244 - ÚOCHB 2024 RIV US eng J - Journal Article
Štefek, Milan - Chalupská, Dominika - Chalupský, Karel - Zgarbová, Michala - Dvořáková, Alexandra - Krafčíková, Petra - Li, A. S. M. - Šála, Michal - Dejmek, Milan - Otava, Tomáš - Chaloupecká, Ema - Kozák, Jaroslav - Kozic, Ján - Vedadi, M. - Weber, Jan - Mertlíková-Kaiserová, Helena - Nencka, Radim
Rational Design of Highly Potent SARS-CoV-2 nsp14 Methyltransferase Inhibitors.
ACS Omega. Roč. 8, č. 30 (2023), s. 27410-27418. ISSN 2470-1343. E-ISSN 2470-1343
R&D Projects: GA MZd(CZ) NU20-05-00472; GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Keywords : SARS-CoV-2 * genetics * inhibitors
OECD category: Virology
Impact factor: 4.1, year: 2022
Method of publishing: Open access
https://doi.org/10.1021/acsomega.3c02815
Permanent Link: https://hdl.handle.net/11104/0344580File Download Size Commentary Version Access acsomega.3c02815 (2).pdf 0 5.1 MB Publisher’s postprint open-access - 3.0569149 - ÚOCHB 2024 RIV NL eng J - Journal Article
Li, F. - Ghiabi, P. - Hajian, T. - Klíma, Martin - Li, A. S. M. - Yazdi, A. K. - Chau, I. - Loppnau, P. - Kutera, M. - Seitova, A. - Bolotokova, A. - Hutchinson, A. - Perveen, S. - Bouřa, Evžen - Vedadi, M.
SS148 and WZ16 inhibit the activities of nsp10-nsp16 complexes from all seven human pathogenic coronaviruses.
Biochimica et Biophysica Acta-General Subjects. Roč. 1867, č. 4 (2023), č. článku 130319. ISSN 0304-4165. E-ISSN 1872-8006
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : RNA methyltransferase * viral protein * enzyme purification * enzyme kinetics * RNA virus * nsp10-nsp16 complex * coronavirus
OECD category: Biochemistry and molecular biology
Impact factor: 3, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.bbagen.2023.130319
Permanent Link: https://hdl.handle.net/11104/0340473