Search results
- 1.0579804 - ÚMG 2024 RIV US eng J - Journal Article
Mejdrova, I. - Dušek, J. - Škach, K. - Štefela, A. - Škoda, J. - Chalupský, Karel - Dohnalová, Klára - Pávková, I. - Kronenberger, T. - Rashidian, A. - Smutná, L. - Duchoslav, V. - Smutný, T. - Pávek, P. - Nencka, R.
Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure.
Journal of Medicinal Chemistry. Roč. 66, č. 4 (2023), s. 2422-2456. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT(CZ) LM2015040; GA ČR GA22-05167S; GA MŠMT ED2.1.00/19.0395
Institutional support: RVO:68378050
Keywords : pregnane-x-receptor * car * activation * pxr * ligand * derivatives * identification * artemisinin * metabolites * expression
OECD category: Cell biology
Impact factor: 7.3, year: 2022
Method of publishing: Open access
https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c01140
Permanent Link: https://hdl.handle.net/11104/0348603 - 2.0569356 - ÚOCHB 2024 RIV US eng J - Journal Article
Mejdrová, Ivana - Dušek, J. - Škach, Kryštof - Štefela, A. - Škoda, J. - Chalupský, Karel - Dohnalová, K. - Pavková, I. - Kronenberger, T. - Rashidian, A. - Smutná, L. - Duchoslav, Vojtěch - Smutný, T. - Pávek, P. - Nencka, Radim
Discovery of Novel Human Constitutive Androstane Receptor Agonists with the Imidazo[1,2-a]pyridine Structure.
Journal of Medicinal Chemistry. Roč. 66, č. 4 (2023), s. 2422-2456. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA TA ČR(CZ) TN01000013
Institutional support: RVO:61388963
Keywords : pregnane X receptor * CAR * activation
OECD category: Pharmacology and pharmacy
Impact factor: 7.3, year: 2022
Method of publishing: Open access
https://doi.org/10.1021/acs.jmedchem.2c01140
Permanent Link: https://hdl.handle.net/11104/0340675
Research data: Zenodo - 3.0565349 - ÚOCHB 2024 RIV DE eng J - Journal Article
Díaz-Holguín, A. - Rashidian, A. - Pijnenburg, D. - Monteiro Ferreira, G. - Štefela, A. - Kašpar, Miroslav - Kudová, Eva - Poso, A. - van Beuningen, R. - Pávek, P. - Kronenberger, T.
When Two Become One: Conformational Changes in FXR/RXR Heterodimers Bound to Steroidal Antagonists.
ChemMedChem. Roč. 18, č. 4 (2023), č. článku e202200556. ISSN 1860-7179. E-ISSN 1860-7187
Institutional support: RVO:61388963
Keywords : bile acids * molecular dynamics simulations * nuclear receptors * farnesoid X receptor
OECD category: Organic chemistry
Impact factor: 3.4, year: 2022
Method of publishing: Open access
https://doi.org/10.1002/cmdc.202200556
Permanent Link: https://hdl.handle.net/11104/0336902
Research data: Zenodo