Search results
- 1.0585467 - MBÚ 2025 RIV NL eng J - Journal Article
Lepesheva, Anna - Grobarčíková, Michaela - Osičková, Adriana - Jurnečka, David - Knoblochová, Šárka - Čížková, Monika - Osička, Radim - Šebo, Peter - Mašín, Jiří
Modification of the RTX domain cap by acyl chains of adapted length rules the formation of functional hemolysin pores.
Biochimica Et Biophysica Acta-Biomembranes. Roč. 1866, č. 5 (2024), s. 184311. ISSN 0005-2736. E-ISSN 1879-2642
R&D Projects: GA ČR(CZ) GA22-15825S; GA ČR(CZ) GA22-01558S; GA ČR(CZ) GX19-27630X; GA MŠMT(CZ) LX22NPO5103; GA MŠMT(CZ) EH22_008/0004597
Research Infrastructure: EATRIS-CZ IV - 90253; CIISB III - 90242
Institutional support: RVO:61388971
Keywords : RTX toxin * Adenylate cyclase toxin * α-Hemolysin * Chimera * Fatty acylation * Cytotoxicity
OECD category: Microbiology
Impact factor: 3.4, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0005273624000427?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0353157File Download Size Commentary Version Access Modification of the RTX.pdf 2 3 MB Publisher’s postprint open-access
Research data: the ProteomeXchange Consortium via the PRIDE partner repository with the data set identifier PXD046160 - 2.0573968 - MBÚ 2024 RIV NL eng J - Journal Article
Osičková, Adriana - Knoblochová, Šárka - Bumba, Ladislav - Man, Petr - Kalaninová, Zuzana - Lepesheva, Anna - Jurnečka, David - Čížková, Monika - Biedermannová, Lada - Goldsmith, J. A. - Maynard, J. A. - McLellan, J. S. - Osička, Radim - Šebo, Peter - Mašín, Jiří
A conserved tryptophan in the acylated segment of RTX toxins controls their βinf2/inf integrin–independent cell penetration.
Journal of Biological Chemistry. Roč. 299, č. 8 (2023), č. článku 104978. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA ČR(CZ) GA22-01558S; GA ČR(CZ) GA22-01558S; GA MŠMT(CZ) LX22NPO5103; GA MŠMT(CZ) EF18_046/0015974; GA ČR(CZ) GX19-27630X
Research Infrastructure: e-INFRA CZ - 90140; EATRIS-CZ IV - 90253; CIISB III - 90242
Institutional support: RVO:61388971 ; RVO:86652036
Keywords : acylated segment * adenylate cyclase toxin * cytotoxicity * hydrogen/deuterium exchange * RTX toxin * thermal stability * tryptophan residue * α-hemolysin * β integrins 2
OECD category: Microbiology
Impact factor: 4.8, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0021925823020069?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0344352 - 3.0547497 - MBÚ 2022 RIV DE eng J - Journal Article
Lepesheva, Anna - Osičková, Adriana - Holubová, Jana - Jurnečka, David - Knoblochová, Šárka - Espinosa-Vinals, Carlos Angel - Bumba, Ladislav - Škopová, Karolína - Fišer, Radovan - Osička, Radim - Šebo, Peter - Mašín, Jiří
Different roles of conserved tyrosine residues of the acylated domains in folding and activity of RTX toxins.
Scientific Reports. Roč. 11, č. 1 (2021), č. článku 19814. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA MŠMT(CZ) LM2018133; GA ČR(CZ) GA19-12695S; GA ČR(CZ) GX19-27630X; GA ČR(CZ) GA19-04607S
Research Infrastructure: CIISB II - 90127
Institutional support: RVO:61388971
Keywords : adenylate-cyclase toxin * escherichia-coli hemolysin * bordetella-pertussis cyaa * cell-invasive activity * alpha-hemolysin * membrane translocation * complement receptor-3 * fatty-acylation * calcium * binding
OECD category: Biochemistry and molecular biology
Impact factor: 4.997, year: 2021
Method of publishing: Open access
https://www.nature.com/articles/s41598-021-99112-3
Permanent Link: http://hdl.handle.net/11104/0323712