Search results
- 1.0570600 - ÚŽFG 2024 RIV GB eng J - Journal Article
Lněničková, K. - Vrba, J. - Kosina, P. - Papoušková, B. - Mekadim, Chahrazed - Mrázek, Jakub - Sova, M. - Sovová, E. - Valentová, Kateřina - Křen, Vladimír - Kouřilová, P. - Vrbková, J. - Ulrichová, J.
Metabolic profiling of silymarin constituents in urine and feces of healthy volunteers: A 90-day study.
Journal of Functional Foods. Roč. 100, Jan 23 (2023), č. článku 105391. ISSN 1756-4646. E-ISSN 2214-9414
R&D Projects: GA ČR(CZ) GA18-00132S; GA ČR GA21-00551S; GA MŠMT(CZ) LTC19039
Institutional support: RVO:67985904 ; RVO:61388971
Keywords : flavonolignans * silybin * taxifolin
OECD category: Microbiology; Pharmacology and pharmacy (MBU-M)
Impact factor: 5.6, year: 2022
Method of publishing: Limited access
https://asep.lib.cas.cz/arl-cav/cs/csg/?repo=crepo1&key=37782471041
Permanent Link: https://hdl.handle.net/11104/0341904 - 2.0567079 - MBÚ 2024 RIV NL eng J - Journal Article
Kaci, H. - Bodnárová, S. - Fliszar-Nyul, E. - Lemli, B. - Pelantová, Helena - Valentová, Kateřina - Bakos, E. - Ozvegy-Laczka, C. - Poór, M.
Interaction of luteolin, naringenin, and their sulfate and glucuronide conjugates with human serum albumin, cytochrome P450 (CYP2C9, CYP2C19, and CYP3A4) enzymes and organic anion transporting polypeptide (OATP1B1 and OATP2B1) transporters.
Biomedicine & Pharmacotherapy. Roč. 157, January 23 (2023), č. článku 114078. ISSN 0753-3322. E-ISSN 1950-6007
R&D Projects: GA ČR GA21-00551S
Institutional support: RVO:61388971
Keywords : Luteolin * Naringenin * Sulfate * glucuronide metabolites * Human serum albumin * Cytochrome P450 enzymes * OATP transporters
OECD category: Pharmacology and pharmacy
Impact factor: 7.5, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0753332222014676?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0342645 - 3.0566377 - MBÚ 2023 RIV CH eng J - Journal Article
Hurtová, Martina - Káňová, Kristýna - Dobiasová, S. - Holasová, K. - Čáková, D. - Hoang, L. - Biedermann, David - Kuzma, Marek - Cvačka, Josef - Křen, Vladimír - Viktorová, J. - Valentová, Kateřina
Selectively Halogenated Flavonolignans—Preparation and Antibacterial Activity.
International Journal of Molecular Sciences. Roč. 23, č. 23 (2022), č. článku 15121. E-ISSN 1422-0067
R&D Projects: GA MŠMT(CZ) LTC20070; GA ČR GA21-00551S
EU Projects: European Commission(CZ) CA17104
Institutional support: RVO:61388971 ; RVO:61388963
Keywords : bacteria * biological activity * flavonoids * flavonolignans * halogenation * multidrug resistance
OECD category: Medicinal chemistry; Analytical chemistry (UOCHB-X)
Impact factor: 5.6, year: 2022
Method of publishing: Open access
https://www.mdpi.com/1422-0067/23/23/15121
Permanent Link: https://hdl.handle.net/11104/0337716 - 4.0558662 - MBÚ 2023 RIV GB eng J - Journal Article
Křen, Vladimír - Valentová, Kateřina
Silybin and its congeners: from traditional medicine to molecular effects.
Natural Product Reports. Roč. 39, č. 6 (2022), s. 1264-1281. ISSN 0265-0568. E-ISSN 1460-4752
R&D Projects: GA ČR GA21-00551S; GA MŠMT(CZ) LTC20070
EU Projects: European Commission(CZ) CA17104 - STRATAGEM
Institutional support: RVO:61388971
Keywords : milk thistle * silymarin flavonolignans * in-vitro * silibinin * silychristin * isosilybin * 2,3-dehydrosilybin * diastereoisomers * identification * derivatives
OECD category: Medicinal chemistry
Impact factor: 11.9, year: 2022
Method of publishing: Limited access
https://pubs.rsc.org/en/content/articlelanding/2022/NP/D2NP00013J
Permanent Link: https://hdl.handle.net/11104/0332537 - 5.0557462 - MBÚ 2023 RIV FR eng J - Journal Article
Holasová, K. - Křížkovská, B. - Hoang, L. - Dobiasová, S. - Lipov, J. - Macek, T. - Křen, Vladimír - Valentová, Kateřina - Ruml, T. - Viktorová, J.
Flavonolignans from silymarin modulate antibiotic resistance and virulence in Staphylococcus aureus.
Biomedicine & Pharmacotherapy. Roč. 149, May 2022 (2022), č. článku 112806. ISSN 0753-3322. E-ISSN 1950-6007
R&D Projects: GA MŠMT(CZ) LTC20070; GA ČR GA21-00551S
Institutional support: RVO:61388971
Keywords : nora efflux pump * multidrug-resistance * ampicillin-sulbactam * biofilm formation * pcr assay * silibinin * expression * vitro * antibacterial * derivatives * Flavonolignans * Silybin * Silychristin * Multidrug resistance * Staphylococcus aureus * Efflux pump
OECD category: Pharmacology and pharmacy
Impact factor: 7.5, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0753332222001949?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0331460 - 6.0554672 - MBÚ 2023 RIV CH eng J - Journal Article
Hurtová, Martina - Biedermann, David - Osifová, Zuzana - Cvačka, Josef - Valentová, Kateřina - Křen, Vladimír
Preparation of Synthetic and Natural Derivatives of Flavonoids Using Suzuki-Miyaura Cross-Coupling Reaction.
Molecules. Roč. 27, č. 3 (2022), č. článku 967. E-ISSN 1420-3049
R&D Projects: GA ČR(CZ) GA21-01799S; GA ČR GA21-00551S; GA MŠMT(CZ) LTC20070
Institutional support: RVO:61388971 ; RVO:61388963
Keywords : flavonoids * Suzuki-Miyaura cross-coupling reaction * prenylation * borylation
OECD category: Organic chemistry; Analytical chemistry (UOCHB-X)
Impact factor: 4.6, year: 2022
Method of publishing: Open access
https://www.mdpi.com/1420-3049/27/3/967
Permanent Link: http://hdl.handle.net/11104/0330489 - 7.0547158 - MBÚ 2022 RIV CH eng J - Journal Article
Vrba, J. - Papoušková, B. - Lněničková, K. - Kosina, P. - Křen, Vladimír - Ulrichová, J.
Metabolism of 2,3-Dehydrosilybin A and 2,3-Dehydrosilybin B: A Study with Human Hepatocytes and Recombinant UDP-Glucuronosyltransferases and Sulfotransferases.
Antioxidants. Roč. 10, č. 6 (2021), č. článku 954. E-ISSN 2076-3921
R&D Projects: GA ČR GA21-00551S
Institutional support: RVO:61388971
Keywords : dehydrosilybin * silybin * metabolism * glucuronidation * sulfation * UDP-glucuronosyltransferase * sulfotransferase
OECD category: Biochemistry and molecular biology
Impact factor: 7.675, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2076-3921/10/6/954
Permanent Link: http://hdl.handle.net/11104/0323480 - 8.0547149 - MBÚ 2022 RIV CH eng J - Journal Article
Biedermann, David - Hurtová, Martina - Benada, Oldřich - Valentová, Kateřina - Biedermannová, Lada - Křen, Vladimír
Continuous diastereomeric kinetic resolution—silybins a and b.
Catalysts. Roč. 11, č. 9 (2021), č. článku 1106. E-ISSN 2073-4344
R&D Projects: GA MŠMT(CZ) LTC18071; GA ČR GA21-00551S
Institutional support: RVO:61388971 ; RVO:86652036
Keywords : Silybin * Silybum marianum * Silymarin * milk thistle * lipase * Novozym 435 * diastereomers * resolution * flow reaction
OECD category: Organic chemistry; Physical chemistry (BTO-N)
Impact factor: 4.501, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2073-4344/11/9/1106
Permanent Link: http://hdl.handle.net/11104/0323472