Search results
- 1.0576137 - ÚOCHB 2024 RIV US eng J - Journal Article
Inniss, N. L. - Kozic, Ján - Li, F. - Rosas-Lemus, M. - Minasov, G. - Rybáček, Jiří - Zhu, Y. - Pohl, Radek - Shuvalova, L. - Rulíšek, Lubomír - Brunzelle, J. S. - Bednárová, Lucie - Štefek, Milan - Kormaník, Ján Michael - Andris, Erik - Šebestík, Jaroslav - Li, A. S. M. - Brown, P. J. - Schmitz, U. - Saikatendu, K. - Chang, E. - Nencka, Radim - Vedadi, M. - Satchell, K. J. F.
Discovery of a Druggable, Cryptic Pocket in SARS-CoV-2 nsp16 Using Allosteric Inhibitors.
ACS Infectious Diseases. Roč. 9, č. 10 (2023), s. 1918-1931. ISSN 2373-8227
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA MZd(CZ) NU20-05-00472
Institutional support: RVO:61388963
Keywords : coronavirus * NSP16 methyltransferase * covalent inhibitors * structural biology * antiviral
OECD category: Virology
Impact factor: 5.3, year: 2022
Method of publishing: Limited access
https://doi.org/10.1021/acsinfecdis.3c00203
Permanent Link: https://hdl.handle.net/11104/0345731 - 2.0574244 - ÚOCHB 2024 RIV US eng J - Journal Article
Štefek, Milan - Chalupská, Dominika - Chalupský, Karel - Zgarbová, Michala - Dvořáková, Alexandra - Krafčíková, Petra - Li, A. S. M. - Šála, Michal - Dejmek, Milan - Otava, Tomáš - Chaloupecká, Ema - Kozák, Jaroslav - Kozic, Ján - Vedadi, M. - Weber, Jan - Mertlíková-Kaiserová, Helena - Nencka, Radim
Rational Design of Highly Potent SARS-CoV-2 nsp14 Methyltransferase Inhibitors.
ACS Omega. Roč. 8, č. 30 (2023), s. 27410-27418. ISSN 2470-1343. E-ISSN 2470-1343
R&D Projects: GA MZd(CZ) NU20-05-00472; GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Keywords : SARS-CoV-2 * genetics * inhibitors
OECD category: Virology
Impact factor: 4.1, year: 2022
Method of publishing: Open access
https://doi.org/10.1021/acsomega.3c02815
Permanent Link: https://hdl.handle.net/11104/0344580File Download Size Commentary Version Access acsomega.3c02815 (2).pdf 0 5.1 MB Publisher’s postprint open-access - 3.0574061 - ÚOCHB 2024 RIV NL eng J - Journal Article
Škvára, Petr - Chalupská, Dominika - Klíma, Martin - Kozic, Ján - Šilhán, Jan - Bouřa, Evžen
Structural basis for RNA-cap recognition and methylation by the mpox methyltransferase VP39.
Antiviral Research. Roč. 216, August (2023), č. článku 105663. ISSN 0166-3542. E-ISSN 1872-9096
R&D Projects: GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Keywords : messenger-RNA * virus methyltransferase
OECD category: Virology
Impact factor: 7.6, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.antiviral.2023.105663
Permanent Link: https://hdl.handle.net/11104/0344428File Download Size Commentary Version Access 10.1016j.antiviral.2023.105663.pdf 1 3 MB Publisher’s postprint open-access
Research data: PDB - 4.0571446 - ÚOCHB 2024 RIV US eng J - Journal Article
Šilhán, Jan - Klíma, Martin - Otava, Tomáš - Škvára, Petr - Chalupská, Dominika - Chalupský, Karel - Kozic, Ján - Nencka, Radim - Bouřa, Evžen
Discovery and structural characterization of monkeypox virus methyltransferase VP39 inhibitors reveal similarities to SARS-CoV-2 nsp14 methyltransferase.
Nature Communications. Roč. 14, April (2023), č. článku 2259. E-ISSN 2041-1723
R&D Projects: GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Keywords : messenger RNA * recognition * binding
OECD category: Virology
Impact factor: 16.6, year: 2022
Method of publishing: Open access
https://doi.org/10.1038/s41467-023-38019-1
Permanent Link: https://hdl.handle.net/11104/0342665File Download Size Commentary Version Access 10.1038s41467-023-38019-1.pdf 0 1.9 MB Publisher’s postprint open-access - 5.0544176 - ÚOCHB 2022 RIV US eng J - Journal Article
Dostalík, Pavel - Krafčíková, Petra - Šilhán, Jan - Kozic, Ján - Chalupská, Dominika - Chalupský, Karel - Bouřa, Evžen
Structural Analysis of the OC43 Coronavirus 2′-O-RNA Methyltransferase.
Journal of Virology. Roč. 95, č. 15 (2021), č. článku e00463-21. ISSN 0022-538X. E-ISSN 1098-5514
R&D Projects: GA ČR(CZ) GA21-25280S
Institutional support: RVO:61388963
Keywords : OC43 * coronavirus * crystal structure * methyltransferase
OECD category: Biochemistry and molecular biology
Impact factor: 6.549, year: 2021
Method of publishing: Open access with time embargo
https://doi.org/10.1128/JVI.00463-21
Permanent Link: http://hdl.handle.net/11104/0321236