Search results
- 1.0585365 - FGÚ 2025 RIV GB eng J - Journal Article
Chvíla, S. - Kubová, Hana - Mareš, Pavel - Kudová, Eva - Štěpánek, F.
A zuranolone nanocrystal formulation enables solubility-independent in vivo study of pentylenetetrazol-induced seizures in a rat model.
RSC Pharmaceutics. Roč. 1, č. 1 (2024), s. 37-46. E-ISSN 2976-8713
R&D Projects: GA MŠMT(CZ) LX22NPO5104; GA MZd(CZ) EF16_025/0007444
Institutional support: RVO:67985823 ; RVO:61388963
Keywords : nanocrystal formulation * neuroactive steroids * zuranolone * solubility * epilepsy
OECD category: Neurosciences (including psychophysiology
Method of publishing: Open access
https://doi.org/10.1039/D3PM00043E
Permanent Link: https://hdl.handle.net/11104/0353090File Download Size Commentary Version Access 24_0037_0585365.pdf 1 1.5 MB Publisher’s postprint open-access - 2.0583680 - FGÚ 2025 RIV NL eng J - Journal Article
Lebedeva, M. - Kubištová, A. - Spišská, V. - Filipovská, E. - Pačesová, D. - Svobodová, I. - Kuchtiak, Viktor - Balík, Aleš - Bendová, Z.
The disruption of circadian rhythmicity of gene expression in the hippocampus and associated structures in Gria2R/R mice, a comparison with C57BL/6J and Adar2−/− mice strains.
Brain Research. Roč. 1826, 1 March (2024), č. článku 148739. ISSN 0006-8993. E-ISSN 1872-6240
R&D Projects: GA MZd(CZ) EF16_025/0007444
Institutional support: RVO:67985823
Keywords : circadian rhythms * Adar2 * Gria2 * mice * hippocampus * suprachiasmatic nucleus
OECD category: Neurosciences (including psychophysiology
Impact factor: 2.9, year: 2022
https://doi.org/10.1016/j.brainres.2023.148739
Permanent Link: https://hdl.handle.net/11104/0352122 - 3.0583244 - FGÚ 2025 RIV CH eng J - Journal Article
Kysilov, Bohdan - Kuchtiak, Viktor - Hrčka Krausová, Barbora - Balík, Aleš - Kořínek, Miloslav - Fili, Klevinda - Dobrovolski, Mark - Abramová, Vera - Chodounská, Hana - Kudová, Eva - Božíková, Paulina - Černý, Jiří - Smejkalová, Tereza - Vyklický ml., Ladislav
Disease-associated nonsense and frame-shift variants resulting in the truncation of the GluN2A or GluN2B C-terminal domain decrease NMDAR surface expression and reduce potentiating effects of neurosteroids.
Cellular and Molecular Life Sciences. Roč. 81, č. 1 (2024), č. článku 36. ISSN 1420-682X. E-ISSN 1420-9071
R&D Projects: GA ČR(CZ) GA23-04922S; GA TA ČR(CZ) TN02000109; GA MZd(CZ) EF16_025/0007444
Institutional support: RVO:67985823 ; RVO:61388963 ; RVO:86652036
Keywords : glutamate receptors * channelopathy * endogenous neuroactive steroid * GRIN2 genes * surface expression * rescue pharmacology
OECD category: Neurosciences (including psychophysiology
Impact factor: 8, year: 2022
Method of publishing: Open access
https://doi.org/10.1007/s00018-023-05062-6
Permanent Link: https://hdl.handle.net/11104/0351253 - 4.0572804 - FGÚ 2024 RIV US eng J - Journal Article
Abramová, Vera - Leal Alvarado, Vanessa - Hill, M. - Smejkalová, Tereza - Malý, Michal - Valeš, Karel - Dittert, Ivan - Božíková, Paulina - Kysilov, Bohdan - Hrčka Krausová, Barbora - Vyklický, Vojtěch - Balík, Aleš - Fili, Klevinda - Kořínek, Miloslav - Chodounská, Hana - Kudová, Eva - Číž, D. - Martinovič, J. - Černý, Jiří - Bartůněk, Petr - Vyklický ml., Ladislav
Effects of Pregnanolone Glutamate and Its Metabolites on GABAA and NMDA Receptors and Zebrafish Behavior.
ACS Chemical Neuroscience. Roč. 14, č. 10 (2023), s. 1870-1883. ISSN 1948-7193. E-ISSN 1948-7193
R&D Projects: GA MZd(CZ) EF16_025/0007444; GA MŠMT LM2023052; GA ČR(CZ) GA23-04922S; GA TA ČR(CZ) TN02000109
Research Infrastructure: CZ-OPENSCREEN IV - 90252
Institutional support: RVO:67985823 ; RVO:86652036 ; RVO:61388963 ; RVO:68378050
Keywords : negative allosteric modulator * thigmotaxis * steroid * glutamate * zebrafish
OECD category: Neurosciences (including psychophysiology; Neurosciences (including psychophysiology (UOCHB-X); Biochemistry and molecular biology (UMG-J); Biochemistry and molecular biology (BTO-N)
Impact factor: 5, year: 2022
Method of publishing: Limited access
https://doi.org/10.1021/acschemneuro.3c00131
Permanent Link: https://hdl.handle.net/11104/0343402 - 5.0559495 - ÚOCHB 2023 RIV US eng J - Journal Article
Kašpar, Miroslav - Kudová, Eva
Selectivity of Oxidizing Agents toward Axial and Equatorial Hydroxyl Groups.
Journal of Organic Chemistry. Roč. 87, č. 14 (2022), s. 9157-9170. ISSN 0022-3263. E-ISSN 1520-6904
R&D Projects: GA MZd(CZ) EF16_025/0007444; GA TA ČR(CZ) TN01000013
Institutional support: RVO:61388963
Keywords : secondary alcohols * dimethyl-sulfoxide * oxidation
OECD category: Organic chemistry
Impact factor: 3.6, year: 2022
Method of publishing: Limited access
https://doi.org/10.1021/acs.joc.2c00877
Permanent Link: https://hdl.handle.net/11104/0332776 - 6.0558978 - FGÚ 2023 RIV GB eng J - Journal Article
Kysilov, Bohdan - Hrčka Krausová, Barbora - Vyklický, Vojtěch - Smejkalová, Tereza - Kořínek, Miloslav - Horák, Martin - Chodounská, Hana - Kudová, Eva - Černý, Jiří - Vyklický ml., Ladislav
Pregnane-based steroids are novel positive NMDA receptor modulators that may compensate for the effect of loss-of-function disease-associated GRIN mutations.
British Journal of Pharmacology. Roč. 179, č. 15 (2022), s. 3970-3990. ISSN 0007-1188. E-ISSN 1476-5381
R&D Projects: GA ČR(CZ) GA20-17945S; GA MZd(CZ) EF16_025/0007444; GA TA ČR(CZ) TN01000013
Institutional support: RVO:67985823 ; RVO:61388963
Keywords : GRIN channelopathy * NMDA receptor * positive allosteric modulator * steroids * transmembrane domain
OECD category: Neurosciences (including psychophysiology
Impact factor: 7.3, year: 2022
Method of publishing: Open access
https://doi.org/10.1111/bph.15841
Permanent Link: https://hdl.handle.net/11104/0332640 - 7.0558805 - FGÚ 2023 RIV GB eng J - Journal Article
Rudolfová, V. - Petrásek, Tomáš - Antošová, E. - Frynta, D. - Landová, E. - Valeš, Karel - Nekovářová, Tereza
Inter-individual differences in laboratory rats as revealed by three behavioural tasks.
Scientific Reports. Roč. 12, č. 1 (2022), č. článku 9361. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA MZd(CZ) EF16_025/0007444; GA ČR(CZ) GA22-15096S
Institutional support: RVO:67985823
Keywords : elevated plus-maze * open-field behavior * Morris water maze * animal-model * mice * traits
OECD category: Neurosciences (including psychophysiology
Impact factor: 4.6, year: 2022
Method of publishing: Open access
https://doi.org/10.1038/s41598-022-13288-w
Permanent Link: https://hdl.handle.net/11104/0332649 - 8.0558551 - ÚOCHB 2023 RIV US eng J - Journal Article
Solntseva, E. I. - Bukanova, J. V. - Skrebitsky, V. G. - Kudová, Eva
Pregnane neurosteroids exert opposite effects on GABA and glycine-induced chloride current in isolated rat neurons.
Hippocampus. Roč. 32, č. 7 (2022), s. 552-563. ISSN 1050-9631. E-ISSN 1098-1063
R&D Projects: GA MZd(CZ) EF16_025/0007444
Institutional support: RVO:61388963
Keywords : GABA(A) receptor * glycine receptor * neurosteroid * pregnane * structure-activity relationship study
OECD category: Neurosciences (including psychophysiology
Impact factor: 3.5, year: 2022
Method of publishing: Limited access
https://doi.org/10.1002/hipo.23449
Permanent Link: http://hdl.handle.net/11104/0332190 - 9.0557063 - FGÚ 2023 RIV NL eng J - Journal Article
Kolář, D. - Kletečková, L. - Skálová, K. - Brožka, Hana - Kalous, M. - Valeš, Karel
Glycolytic and Krebs cycle enzymes activity in rat prefrontal cortex, hippocampus, and striatum after single and repeated NMDA inhibition by MK-801.
Neurotoxicology. Roč. 90, May (2022), s. 35-47. ISSN 0161-813X. E-ISSN 1872-9711
R&D Projects: GA ČR(CZ) GA18-09296S; GA MZd(CZ) EF16_025/0007444; GA MZd(CZ) NU20-04-00389; GA ČR(CZ) GA22-15096S
Institutional support: RVO:67985823
Keywords : energy metabolism * hexokinase * lactate dehydrogenase * citrate synthase * malate dehydrogenase * schizophrenia
OECD category: Pharmacology and pharmacy
Impact factor: 3.4, year: 2022
Method of publishing: Limited access
https://doi.org/10.1016/j.neuro.2022.02.005
Permanent Link: http://hdl.handle.net/11104/0331183 - 10.0556130 - FGÚ 2023 RIV CH eng J - Journal Article
Fábera, Petr - Uttl, Libor - Kubová, Hana - Tsenov, Grygoriy - Mareš, Pavel
Adenosine Kinase Isoforms in the Developing Rat Hippocampus after LiCl/Pilocarpine Status Epilepticus.
International Journal of Molecular Sciences. Roč. 23, č. 5 (2022), č. článku 2510. E-ISSN 1422-0067
R&D Projects: GA ČR(CZ) GA19-11931S; GA MZd(CZ) EF16_025/0007444; GA ČR(CZ) GA18-09296S
Institutional support: RVO:67985823
Keywords : adenosine kinase * isoforms * inhibitor * development * hippocampus * epileptic afterdischarges * rat * LiCl/pilocarpine * status epilepticus
OECD category: Pharmacology and pharmacy
Impact factor: 5.6, year: 2022
Method of publishing: Open access
https://www.mdpi.com/1422-0067/23/5/2510
Permanent Link: http://hdl.handle.net/11104/0330483