Search results
- 1.0566362 - ÚVGZ 2023 RIV CH eng J - Journal Article
Strharsky, T. - Pindjakova, D. - Kos, J. - Vrablova, L. - Smak, P. - Michnová, H. - Gonec, T. - Hošek, J. - Oravec, Michal - Jendrzejewska, I. - Čížek, A. - Jampílek, J.
Trifluoromethylcinnamanilide Michael Acceptors for Treatment of Resistant Bacterial Infections.
International Journal of Molecular Sciences. Roč. 23, č. 23 (2022), č. článku 15090. E-ISSN 1422-0067
R&D Projects: GA MŠMT(CZ) LM2018123; GA MŠMT(CZ) EF16_019/0000797
Institutional support: RVO:86652079
Keywords : cinnamamides * Michael acceptors * antimicrobial activity * cytotoxicity * lipophilicity * structure-activity relationships * docking study
OECD category: Biochemistry and molecular biology
Impact factor: 5.6, year: 2022
Method of publishing: Open access
https://www.mdpi.com/1422-0067/23/23/15090
Permanent Link: https://hdl.handle.net/11104/0337705File Download Size Commentary Version Access ijms-23-15090.pdf 3 4.8 MB Publisher’s postprint open-access - 2.0558879 - ÚVGZ 2023 RIV CH eng J - Journal Article
Gonec, T. - Pindjakova, D. - Vrablova, L. - Strharsky, T. - Michnova, H. - Kauerová, T. - Kollár, P. - Oravec, Michal - Jendrzejewska, I. - Čížek, A. - Jampílek, J.
Antistaphylococcal Activities and ADME-Related Properties of Chlorinated Arylcarbamoylnaphthalenylcarbamates.
Pharmaceuticals. Roč. 15, č. 6 (2022), č. článku 715. E-ISSN 1424-8247
R&D Projects: GA MŠMT(CZ) LM2018123; GA MŠMT(CZ) EF16_019/0000797
Institutional support: RVO:86652079
Keywords : antimicrobial activity * staphylococcus-aureus * biological-activity * resistance * derivatives * permeability * mechanisms * spectrum * design * oxides * hydroxynaphthalenes * carbamates * antistaphylococcal activity * cytotoxicity * lipophilicity * structure-activity relationships
OECD category: Pharmacology and pharmacy
Impact factor: 4.6, year: 2022
Method of publishing: Open access
https://www.mdpi.com/1424-8247/15/6/715
Permanent Link: http://hdl.handle.net/11104/0332380 - 3.0556983 - ÚVGZ 2023 RIV CH eng J - Journal Article
Strharsky, T. - Pindjakova, D. - Kos, J. - Vrablova, L. - Michnová, H. - Hošek, J. - Straková, N. - Leláková, V. - Leva, L. - Kavanová, L. - Oravec, Michal - Čížek, A. - Jampílek, J.
Study of Biological Activities and ADMET-Related Properties of Novel Chlorinated N-arylcinnamamides.
International Journal of Molecular Sciences. Roč. 23, č. 6 (2022), č. článku 3159. E-ISSN 1422-0067
R&D Projects: GA MŠMT(CZ) EF16_019/0000797; GA MŠMT(CZ) LM2018123
Institutional support: RVO:86652079
Keywords : herbicidal activity * inhibiting activity * antimycobacterial * spectrum * antibacterial * derivatives * bonds * cinnamamides * antimicrobial activity * cytotoxicity * lipophilicity * structure-activity relationships
OECD category: Biochemistry and molecular biology
Impact factor: 5.6, year: 2022
Method of publishing: Open access
https://www.mdpi.com/1422-0067/23/6/3159
Permanent Link: http://hdl.handle.net/11104/0331109 - 4.0543720 - ÚVGZ 2022 RIV CH eng J - Journal Article
Kos, J. - Strharsky, T. - Štěpánková, Š. - Svrčková, K. - Oravec, Michal - Hošek, J. - Imramovský, A. - Jampílek, J.
Trimethoxycinnamates and Their Cholinesterase Inhibitory Activity.
Applied Sciences-Basel. Roč. 11, č. 10 (2021), č. článku 4691. E-ISSN 2076-3417
R&D Projects: GA MŠMT(CZ) EF16_019/0000797; GA MŠMT(CZ) LM2015061
Research Infrastructure: CzeCOS III - 90123
Institutional support: RVO:86652079
Keywords : biological evaluation * 3,4,5-trimethoxycinnamic acid * butyrylcholinesterase * acetylcholinesterase * derivatives * design * discovery * analogs * hybrids * trimethoxycinnamates * cholinesterase-inhibiting activity * cytotoxicity * structure-activity relationships
OECD category: Organic chemistry
Impact factor: 2.838, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2076-3417/11/10/4691
Permanent Link: http://hdl.handle.net/11104/0320889 - 5.0536266 - ÚVGZ 2021 RIV CH eng J - Journal Article
Kos, J. - Bak, A. - Kozik, V. - Jankech, T. - Strharsky, T. - Swietlicka, A. - Michnova, H. - Hošek, J. - Smolinski, A. - Oravec, Michal - Devinsky, F. - Hutta, M. - Jampílek, J.
Biological Activities and ADMET-Related Properties of Novel Set of Cinnamanilides dagger.
Molecules. Roč. 25, č. 18 (2020), č. článku 4121. E-ISSN 1420-3049
R&D Projects: GA MŠMT(CZ) EF16_019/0000797
Institutional support: RVO:86652079
Keywords : molecular lipophilicity * drug discovery * log-p * som-4d-qsar * prediction * hybrids * agents * pk(a) * dye * cinnamamides * synthesis * antistaphylococcal activity * MTT assay * cytotoxicity * lipophilicity * pca * ive-pls * quantitative structure-property relationships
OECD category: Demography
Impact factor: 4.412, year: 2020
Method of publishing: Open access
https://www.mdpi.com/1420-3049/25/18/4121
Permanent Link: http://hdl.handle.net/11104/0314080