Search results
- 1.0567469 - ÚMG 2023 RIV CH eng J - Journal Article
Součková, O. - Škopová, V. - Barešová, V. - Sedlák, David - Bleyer, A. J. - Kmoch, S. - Zikánová, M.
Metabolites of De Novo Purine Synthesis: Metabolic Regulators and Cytotoxic Compounds.
Metabolites. Roč. 12, č. 12 (2022), č. článku 1210. E-ISSN 2218-1989
R&D Projects: GA MŠMT(CZ) LM2018130
Research Infrastructure: NCMG II - 90132
Institutional support: RVO:68378050
Keywords : purine synthesis * pfas * paics * adsl * atic * cytotoxicity * fgar * air * saicar * aicar
OECD category: Biochemistry and molecular biology
Impact factor: 4.1, year: 2022
Method of publishing: Open access
https://www.mdpi.com/2218-1989/12/12/1210
Permanent Link: https://hdl.handle.net/11104/0338718 - 2.0566380 - ÚMG 2023 RIV CH eng J - Journal Article
Hason, Martina - Jovičić, Jovana - Vonková, Ivana - Bojić, Milan - Simon-Vermot, T. - White, R.M. - Bartůněk, Petr
Bioluminescent zebrafish transplantation model for drug discovery.
Frontiers in Pharmacology. Roč. 13, April (2022), č. článku 893655. ISSN 1663-9812. E-ISSN 1663-9812
R&D Projects: GA ČR(CZ) GA18-18363S; GA MŠMT(CZ) LM2018130
Institutional support: RVO:68378050
Keywords : bioluminescence * cancer * high-throughput screening * inhibitor * xenotransplantation * zebrafish
OECD category: Pharmacology and pharmacy
Impact factor: 5.6, year: 2022
Method of publishing: Open access
https://www.frontiersin.org/articles/10.3389/fphar.2022.893655/full
Permanent Link: https://hdl.handle.net/11104/0337747 - 3.0566015 - ÚMG 2023 RIV US eng J - Journal Article
Ryšánek, David - Vašicová, Pavla - Kolla, Jayaprakash Narayana - Sedlák, David - Anděra, Ladislav - Bártek, Jiří - Hodný, Zdeněk
Synergism of BCL-2 family inhibitors facilitates selective elimination of senescent cells.
Aging. Roč. 14, č. 16 (2022), s. 6381-6414. ISSN 1945-4589
R&D Projects: GA MŠMT(CZ) LM2018129; GA MŠMT(CZ) EF18_046/0016045; GA ČR(CZ) GA18-14259S; GA MŠMT(CZ) LM2018130; GA MŠMT LX22NPO5102
Institutional support: RVO:68378050
Keywords : homoharringtonine * cellular senescence * bcl-2 * mcl-1 * senolytics
OECD category: Cell biology
Impact factor: 5.2, year: 2022
Method of publishing: Open access
https://www.aging-us.com/article/204207/text
Permanent Link: https://hdl.handle.net/11104/0337451File Download Size Commentary Version Access aging-v14i16-204207.pdf 1 8.5 MB Publisher’s postprint open-access - 4.0564793 - BC 2023 RIV US eng J - Journal Article
Tůmová, Šárka - Miláček, Matěj - Šnajdr, Ivan - Muthu, Magesh - Tůma, R. - Řeha, D. - Jedlička, Pavel - Bittová, Lenka - Novotná, Adéla - Majer, Pavel - Sedlák, David - Jindra, Marek
Unique peptidic agonists of a juvenile hormone receptor with species-specific effects on insect development and reproduction.
Proceedings of the National Academy of Sciences of the United States of America. Roč. 119, č. 48 (2022), č. článku e2215541119. ISSN 0027-8424. E-ISSN 1091-6490
R&D Projects: GA ČR(CZ) GX20-05151X; GA MŠMT(CZ) LM2018130
Institutional support: RVO:60077344 ; RVO:61388963 ; RVO:68378050
Keywords : hormone receptor * juvenile hormone * ligand-binding pocket
OECD category: Biochemistry and molecular biology; Biochemistry and molecular biology (UOCHB-X); Biochemistry and molecular biology (UMG-J)
Impact factor: 11.1, year: 2022
Method of publishing: Limited access
https://www.pnas.org/doi/epdf/10.1073/pnas.2215541119
Permanent Link: https://hdl.handle.net/11104/0336446 - 5.0562743 - ÚMG 2023 RIV DE eng J - Journal Article
Bubanová, D. - Fučíková, A. M. - Majlath, I. - Pajer, Petr - Bjelková, K. - Majlathová, V.
The first detection of relapsing fever spirochete Borrelia miyamotoi in Ixodes ricinus ticks from the northeast Czech Republic.
Ticks and Tick-borne Diseases. Roč. 13, č. 6 (2022), č. článku 102042. ISSN 1877-959X. E-ISSN 1877-9603
R&D Projects: GA MŠMT(CZ) LM2018130
Institutional support: RVO:68378050
Keywords : Borrelia miyamotoi * Vectorborne disease * Czech Republic * Ixodes ricinus * Lipoptena cervi * Lipoptena fortisetosa
OECD category: Microbiology
Impact factor: 3.2, year: 2022
Method of publishing: Limited access
https://doi.org/10.1016/j.ttbdis.2022.102042
Permanent Link: https://hdl.handle.net/11104/0338392 - 6.0558018 - ÚMG 2023 RIV US eng J - Journal Article
Hason, Martina - Mikulášová, Tereza - Machoňová, Olga - Pombinho, António R. - van Ham, T.J. - Irion, U. - Nuesslein-Volhard, C. - Bartůněk, Petr - Svoboda, Ondřej
M-CSFR/CSF1R signaling regulates myeloid fates in zebrafish via distinct action of its receptors and ligands.
Blood Advances. Roč. 6, č. 5 (2022), s. 1474-1488. ISSN 2473-9529. E-ISSN 2473-9537
R&D Projects: GA MŠMT(CZ) LM2018131; GA MŠMT(CZ) LM2018129; GA MŠMT(CZ) EF18_046/0016045; GA ČR(CZ) GA18-18363S; GA MŠMT(CZ) LM2018130
Institutional support: RVO:68378050
Keywords : colony-stimulating factor-1 * in-vitro * macrophage * fms * cells * il-34 * csf1r * granulocytes * progenitor * expression
OECD category: Hematology
Impact factor: 7.6, year: 2022
Method of publishing: Open access
https://ashpublications.org/bloodadvances/article/6/5/1474/483305/M-CSFR-CSF1R-signaling-regulates-myeloid-fates-in
Permanent Link: http://hdl.handle.net/11104/0331932 - 7.0557101 - ÚMG 2023 RIV GB eng J - Journal Article
Králová, Jarmila - Popr, Martin - Valečka, Jan - Bartůněk, Petr
Sterolight as imaging tool to study sterol uptake, trafficking and efflux in living cells.
Scientific Reports. Roč. 12, č. 1 (2022), č. článku 6264. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA MŠMT(CZ) EF18_046/0016045; GA MŠMT(CZ) LM2018129; GA ČR GA17-02836S; GA MŠMT(CZ) LM2018130
Institutional support: RVO:68378050
Keywords : endoplasmic-reticulum * cellular cholesterol * plasma-membrane * intracellular-transport * lipid rafts * endocytosis * caveolin * dehydroergosterol * internalization * homeostasis
OECD category: Cell biology
Impact factor: 4.6, year: 2022
Method of publishing: Open access
https://www.nature.com/articles/s41598-022-10134-x
Permanent Link: http://hdl.handle.net/11104/0331415 - 8.0555982 - ÚMG 2023 RIV US eng J - Journal Article
Příhoda, D. - Maamary, J. - Waight, A. - Juan, V. - Fayadat-Dilman, L. - Svozil, Daniel - Bitton, D.
BioPhi: A platform for antibody design, humanization, and humanness evaluation based on natural antibody repertoires and deep learning.
MAbs. Roč. 14, č. 1 (2022), č. článku e2020203. ISSN 1942-0862. E-ISSN 1942-0870
R&D Projects: GA MŠMT(CZ) LM2018130
Institutional support: RVO:68378050
Keywords : Antibody humanization * humanness * human-likeness * immunogenicity * deimmunization * immune repertoires * machine learning * deep learning
OECD category: Biochemical research methods
Impact factor: 5.3, year: 2022
Method of publishing: Open access
https://www.tandfonline.com/doi/full/10.1080/19420862.2021.2020203
Permanent Link: http://hdl.handle.net/11104/0330851 - 9.0555872 - FGÚ 2023 RIV GB eng J - Journal Article
Štefková-Mazochová, K. - Danda, H. - Dehaen, W. - Jurásek, B. - Šíchová, K. - Pinterová-Leca, N. - Mazoch, V. - Hrčka Krausová, Barbora - Kysilov, Bohdan - Smejkalová, Tereza - Vyklický ml., Ladislav - Kohout, M. - Hájková, K. - Svozil, Daniel - Horsley, R. R. - Kuchař, M. - Páleníček, T.
Pharmacokinetic, pharmacodynamic, and behavioural studies of deschloroketamine in Wistar rats.
British Journal of Pharmacology. Roč. 179, č. 1 (2022), s. 65-83. ISSN 0007-1188. E-ISSN 1476-5381
R&D Projects: GA ČR(CZ) GA20-17945S; GA MZd(CZ) EF16_025/0007444; GA MŠMT(CZ) LM2018130
Research Infrastructure: CZ-OPENSCREEN III - 90130
Institutional support: RVO:67985823 ; RVO:68378050
Keywords : deschloroketamine * enantiomers * locomotion * NMDA receptor * pharmacokinetics * pharmacokinetics
OECD category: Pharmacology and pharmacy
Impact factor: 7.3, year: 2022
Method of publishing: Open access
https://doi.org/10.1111/bph.15680
Permanent Link: http://hdl.handle.net/11104/0330327 - 10.0555591 - ÚMG 2022 RIV GB eng J - Journal Article
Škuta, Ctibor - Southan, C. - Bartůněk, Petr
Will the chemical probes please stand up?
RSC MEDICINAL CHEMISTRY. Roč. 12, č. 8 (2021), s. 1428-1441. E-ISSN 2632-8682
R&D Projects: GA MŠMT(CZ) LM2018130
Research Infrastructure: CZ-OPENSCREEN III - 90130
Institutional support: RVO:68378050
Keywords : interference compounds pains * concise guide * inhibitors * discovery * libraries * drugs
OECD category: Biochemistry and molecular biology
Impact factor: 3.470, year: 2021
Method of publishing: Open access
https://pubs.rsc.org/en/content/articlelanding/2021/MD/D1MD00138H
Permanent Link: http://hdl.handle.net/11104/0330055