Search results
- 1.0586357 - ÚOCHB 2025 RIV NL eng J - Journal Article
Zamani, Mohammad Reza - Hadzima, Martin - Blažková, Kristýna - Šubr, Vladimír - Ormsby, Tereza - Celis-Gutierrez, J. - Malissen, B. - Kostka, Libor - Etrych, Tomáš - Šácha, Pavel - Konvalinka, Jan
Polymer-based antibody mimetics (iBodies) target human PD-L1 and function as a potent immune checkpoint blocker.
Journal of Biological Chemistry. Roč. 300, č. 6 (2024), č. článku 107325. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA MŠMT LX22NPO5102; GA ČR(CZ) GA23-05642S
Institutional support: RVO:61388963 ; RVO:61389013
Keywords : antibody mimetic * HPMA copolymer * mmune checkpoint * immunosuppression * immunotherapy * inhibitor * PD-1 * PD-L1 * T-cell * tumor immunology
Subject RIV: CD - Macromolecular Chemistry (UMCH-V)
OECD category: Polymer science (UMCH-V)
Impact factor: 4.8, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.jbc.2024.107325
Permanent Link: https://hdl.handle.net/11104/0353904File Download Size Commentary Version Access 10.1016j.jbc.2024.107325.pdf 1 1.6 MB Publisher’s postprint open-access - 2.0547173 - ÚMCH 2022 RIV GB eng J - Journal Article
Šubr, Vladimír - Ormsby, Tereza - Šácha, Pavel - Konvalinka, Jan - Etrych, Tomáš - Kostka, Libor
The role of the biotin linker in polymer antibody mimetics, iBodies, in biochemical assays.
Polymer Chemistry. Roč. 12, č. 41 (2021), s. 6009-6021. ISSN 1759-9954. E-ISSN 1759-9962
R&D Projects: GA ČR(CZ) GA19-05649S; GA ČR(CZ) GA19-10280S; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61389013 ; RVO:61388963
Keywords : HPMA * iBody * biotin
OECD category: Polymer science; Biochemical research methods (UOCHB-X)
Impact factor: 5.364, year: 2021
Method of publishing: Limited access
https://pubs.rsc.org/en/content/articlelanding/2021/PY/D1PY00707F
Permanent Link: http://hdl.handle.net/11104/0324045 - 3.0544791 - ÚOCHB 2022 RIV FR eng J - Journal Article
Šimková, Adéla - Ormsby, Tereza - Sidej, Natan - Poštová Slavětínská, Lenka - Brynda, Jiří - Beranová, Jana - Šácha, Pavel - Majer, Pavel - Konvalinka, Jan
Structure-activity relationship and biochemical evaluation of novel fibroblast activation protein and prolyl endopeptidase inhibitors with α-ketoamide warheads.
European Journal of Medicinal Chemistry. Roč. 224, Nov 15 (2021), č. článku 113717. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA ČR(CZ) GA19-10280S; GA MZd(CZ) NV15-31379A; GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) LM2015064
Institutional support: RVO:61388963
Keywords : fibroblast activation protein * seprase * FAP inhibitor * serine protease inhibition * prolyl endopeptidase * α-Ketoamide inhibitor
OECD category: Medicinal chemistry
Impact factor: 7.088, year: 2021
Method of publishing: Open access
https://doi.org/10.1016/j.ejmech.2021.113717
Permanent Link: http://hdl.handle.net/11104/0321598 - 4.0537077 - ÚOCHB 2021 RIV GB eng J - Journal Article
Storck, W. K. - Bicocca, V. T. - Rountree, M. R. - Honda, S. - Ormsby, Tereza - Selker, E. U.
LSD1 prevents aberrant heterochromatin formation in Neurospora crassa.
Nucleic Acids Research. Roč. 48, č. 18 (2020), s. 10199-10210. ISSN 0305-1048. E-ISSN 1362-4962
Institutional support: RVO:61388963
Keywords : DNA methylation * histone H3 * facultative heterochromatin
OECD category: Biochemistry and molecular biology
Impact factor: 16.971, year: 2020
Method of publishing: Open access
https://doi.org/10.1093/nar/gkaa724
Permanent Link: http://hdl.handle.net/11104/0316284 - 5.0525074 - ÚOCHB 2021 RIV US eng J - Journal Article
Wiles, E. T. - McNaught, K. J. - Kaur, G. - Selker, J. M. L. - Ormsby, Tereza - Aravind, L. - Selker, E. U.
Evolutionarily ancient BAH–PHD protein mediates Polycomb silencing.
Proceedings of the National Academy of Sciences of the United States of America. Roč. 117, č. 21 (2020), s. 11614-11623. ISSN 0027-8424. E-ISSN 1091-6490
Institutional support: RVO:61388963
Keywords : epigenetics * facultative heterochromatin * H3K27 methylation * Polycomb repressive complex * histone reader
OECD category: Biochemistry and molecular biology
Impact factor: 11.205, year: 2020
Method of publishing: Limited access
https://www.pnas.org/content/117/21/11614
Permanent Link: http://hdl.handle.net/11104/0309292 - 6.0524148 - ÚOCHB 2021 RIV US eng J - Journal Article
Kronholm, I. - Ormsby, Tereza - McNaught, K. J. - Selker, E. U. - Ketola, T.
Marked Neurospora crassa Strains for Competition Experiments and Bayesian Methods for Fitness Estimates.
G3-Genes, Genomes, Genetics. Roč. 10, č. 4 (2020), s. 1261-1270. ISSN 2160-1836. E-ISSN 2160-1836
Institutional support: RVO:61388963
Keywords : fungi * high resolution melting * competitive fitness * experimental evolution
OECD category: Biochemistry and molecular biology
Impact factor: 3.154, year: 2020
Method of publishing: Open access
https://www.g3journal.org/content/10/4/1261
Permanent Link: http://hdl.handle.net/11104/0308515