Search results
- 1.0571218 - ÚMG 2024 RIV US eng J - Journal Article
Andrš, Martin - Stoy, H. - Boleslavská, Barbora - Chappidi, N. - Kanagaraj, R. - Naščáková, Zuzana - Menon, S. - Rao, S. - Oravetzová, Anna - Dobrovolná, Jana - Surendranath, K. - Lopes, M. - Janščák, Pavel
Excessive reactive oxygen species induce transcription-dependent replication stress.
Nature Communications. Roč. 14, č. 1 (2023), č. článku 1791. E-ISSN 2041-1723
R&D Projects: GA MŠMT(CZ) EF18_046/0016045; GA MŠMT(CZ) LM2018129; GA ČR GA22-08294S; GA ČR GX21-22593X
Institutional support: RVO:68378050
Keywords : DNA-REPLICATION * GENOMIC INSTABILITY * FORK REVERSAL * R-LOOPS * DAMAGE * ARCHITECTURE * CONFLICTS * YEAST
OECD category: Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology
Impact factor: 16.6, year: 2022
Method of publishing: Open access
https://www.nature.com/articles/s41467-023-37341-y
Permanent Link: https://hdl.handle.net/11104/0342497 - 2.0570756 - ÚMG 2024 RIV GB eng J - Journal Article
Han, Z. - Andrš, Martin - Madhavan, B. K. - Kaymak, S. - Sulaj, A. - Kender, Z. - Kopf, S. - Kihm, L. - Pepperkok, R. - Janščák, Pavel - Nawroth, P. - Kumar, V.
The importance of nuclear RAGE-Mcm2 axis in diabetes or cancer-associated replication stress.
Nucleic Acids Research. Roč. 51, č. 5 (2023), s. 2298-2318. ISSN 0305-1048. E-ISSN 1362-4962
R&D Projects: GA ČR GA22-08294S
Institutional support: RVO:68378050
Keywords : GLYCATION END-PRODUCTS * DNA-DAMAGE * GENE ATR * RECEPTOR * RAGE * COLOCALIZATION * CELLS * MUS81 * MECHANISMS * PROTEINS
OECD category: Biochemistry and molecular biology
Impact factor: 14.9, year: 2022
Method of publishing: Open access
https://academic.oup.com/nar/article/51/5/2298/7049327?login=true
Permanent Link: https://hdl.handle.net/11104/0342098 - 3.0567650 - ÚMG 2023 RIV GB eng J - Journal Article
Boleslavská, Barbora - Oravetzová, Anna - Shukla, Kaustubh - Naščáková, Zuzana - Ibini, O. N. - Hašanová, Zdeňka - Andrš, Martin - Kanagaraj, R. - Dobrovolná, Jana - Janščák, Pavel
DDX17 helicase promotes resolution of R-loop-mediated transcription-replication conflicts in human cells.
Nucleic Acids Research. Roč. 50, č. 21 (2022), s. 12274-12290. ISSN 0305-1048. E-ISSN 1362-4962
R&D Projects: GA ČR GA22-08294S; GA ČR GX21-22593X; GA MŠMT LTAUSA19096
Institutional support: RVO:68378050
Keywords : common fragile sites * dna-damage * fork reversal * biotin ligase * rna helicase * stress * phase * yeast * ends * p72
OECD category: Biochemistry and molecular biology
Impact factor: 14.9, year: 2022
Method of publishing: Open access
https://academic.oup.com/nar/article/50/21/12274/6858780?login=true
Permanent Link: https://hdl.handle.net/11104/0338874 - 4.0559749 - ÚMG 2023 RIV CH eng J - Journal Article
Gorecki, L. - Andrš, Martin - Korábečný, J.
Clinical Candidates Targeting the ATR-CHK1-WEE1 Axis in Cancer.
Cancers (Basel). Roč. 13, č. 4 (2021), č. článku 795. E-ISSN 2072-6694
Institutional support: RVO:68378050
Keywords : ATR–CHK1–WEE1 axis * DNA damage response * cell-cycle checkpoints * clinical trials * inhibitors
OECD category: Oncology
Impact factor: 6.575, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2072-6694/13/4/795
Permanent Link: https://hdl.handle.net/11104/0332953 - 5.0559439 - ÚMG 2023 RIV FR eng J - Journal Article
Gorecki, L. - Muthna, D. - Merdita, S. - Andrš, Martin - Kučera, T. - Havelek, R. - Mucková, L. - Kobrlová, T. - Soukup, J. - Krupa, P. - Prchal, L. - Soukup, O. - Roh, J. - Řezáčová, M. - Korábečný, J.
7-Azaindole, 2,7-diazaindole, and 1H-pyrazole as core structures for novel anticancer agents with potential chemosensitizing properties.
European Journal of Medicinal Chemistry. Roč. 240, June (2022), č. článku 114580. ISSN 0223-5234. E-ISSN 1768-3254
Institutional support: RVO:68378050
Keywords : ATR inhibition * Berzosertib * Cancer * Chemosensitization * Cytotoxicity * Glioblastoma
OECD category: Cell biology
Impact factor: 6.7, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/abs/pii/S0223523422004822?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0332860 - 6.0538154 - ÚMG 2021 RIV GB eng J - Journal Article
Gorecki, L. - Andrš, Martin - Řezáčová, M. - Korábečný, J.
Discovery of ATR kinase inhibitor berzosertib (VX-970, M6620): Clinical candidate for cancer therapy.
Pharmacology and Therapeutics. Roč. 210, June (2020), č. článku 107518. ISSN 0163-7258. E-ISSN 1879-016X
R&D Projects: GA ČR GA19-07674S
Institutional support: RVO:68378050
Keywords : ATR kinase inhibitor * Berzosertib * vx-970 * m6620 * DNA damage response * replication stress * cancer * drug development
OECD category: Biochemistry and molecular biology
Impact factor: 12.310, year: 2020
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/abs/pii/S0163725820300462?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0315976 - 7.0538114 - ÚMG 2021 RIV CH eng J - Journal Article
Andrš, Martin - Hašanová, Zdeňka - Oravetzová, Anna - Dobrovolná, Jana - Janščák, Pavel
RECQ5: A Mysterious Helicase at the Interface of DNA Replication and Transcription.
Genes. Roč. 11, č. 2 (2020), č. článku 232. E-ISSN 2073-4425
R&D Projects: GA ČR GA19-07674S; GA MŠMT LTAUSA19096; GA MŠMT(CZ) EF16_013/0001775
Institutional support: RVO:68378050
Keywords : recq5 * transcription-replication conflicts * replication stress * R-loops * DNA repair * genomic instability
OECD category: Biochemistry and molecular biology
Impact factor: 4.096, year: 2020
Method of publishing: Open access
https://www.mdpi.com/2073-4425/11/2/232
Permanent Link: http://hdl.handle.net/11104/0315941 - 8.0524112 - ÚMG 2021 RIV US eng J - Journal Article
Chappidi, N. - Naščáková, Zuzana - Boleslavská, Barbora - Zellweger, R. - Isik, E. - Andrš, Martin - Menon, S. - Dobrovolná, Jana - Pogliano, Ch.B. - Matos, J. - Porro, A. - Lopes, M. - Janščák, Pavel
Fork Cleavage-Religation Cycle and Active Transcription Mediate Replication Restart after Fork Stalling at Co-transcriptional R-Loops.
Molecular Cell. Roč. 77, č. 3 (2020), s. 528-541. ISSN 1097-2765. E-ISSN 1097-4164
R&D Projects: GA ČR GA17-02080S; GA MŠMT(CZ) LM2015062
Institutional support: RVO:68378050
Keywords : dna-damage * repair * conflicts * resolution * reversal * protein * genome * stress * instability * activation
OECD category: Cell biology
Impact factor: 17.970, year: 2020
Method of publishing: Limited access
https://www.cell.com/molecular-cell/fulltext/S1097-2765(19)30804-4?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1097276519308044%3Fshowall%3Dtrue
Permanent Link: http://hdl.handle.net/11104/0308455