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- 1.0523953 - ÚEB 2021 RIV CH eng J - Journal Article
Salas, C. O. - Zarate, A. M. - Kryštof, Vladimír - Mella, J. - Faundez, M. - Brea, J. - Loza, M. I. - Brito, I. - Hendrychová, Denisa - Jorda, Radek - Cabrera, A. R. - Tapia, R. A. - Espinosa-Bustos, C.
Promising 2,6,9-trisubstituted purine derivatives for anticancer compounds: Synthesis, 3D-QSAR, and preliminary biological assays.
International Journal of Molecular Sciences. Roč. 21, č. 1 (2020), č. článku 161. E-ISSN 1422-0067
Institutional support: RVO:61389030
Keywords : 3d-qsar * Apoptosis * Cancer * Cell cycle * Cytotoxicity * Purine derivatives
OECD category: Oncology
Impact factor: 5.924, year: 2020
Method of publishing: Open access
http://doi.org/10.3390/ijms21010161
Permanent Link: http://hdl.handle.net/11104/0308263File Download Size Commentary Version Access 2020_Salas_INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES_161.pdf 1 5.1 MB Other open-access - 2.0521912 - ÚEB 2020 RIV US eng J - Journal Article
Bertrand, J. - Dostálová, Hana - Kryštof, Vladimír - Jorda, Radek - Castro, A. - Mella, J. - Espinosa-Bustos, C. - María Zarate, A. - Salas, C. O.
New 2,6,9-trisubstituted purine derivatives as Bcr-Abl and Btk inhibitors and as promising agents against leukemia.
Bioorganic Chemistry. Roč. 94, JAN (2020), č. článku 103361. ISSN 0045-2068. E-ISSN 1090-2120
Institutional support: RVO:61389030
Keywords : Bcr-Abl inhibitors * Btk inhibitors * Docking * Leukemia * Purine derivatives * qsar
OECD category: Technologies involving identifying the functioning of DNA, proteins and enzymes and how they influence the onset of disease and maintenance of well-being (gene-based diagnostics and therapeutic interventions (pharmacogenomics, gene-based therapeutics)
Impact factor: 5.275, year: 2020
Method of publishing: Open access
http://dx.doi.org/10.1016/j.bioorg.2019.103361
Permanent Link: http://hdl.handle.net/11104/0306457File Download Size Commentary Version Access 2020_Bertrand_Bioorganic Chemistry_103361.pdf 2 3 MB Other open-access