Search results
- 1.0571539 - BTÚ 2024 RIV US eng J - Journal Article
Temml, V. - Kollar, J. - Schoenleitner, T. - Hoell, A. - Schuster, D. - Kutil, Zsofia
Combination of In Silico and In Vitro Screening to Identify Novel Glutamate II Inhibitors.
Journal of Chemical Information and Modeling. Roč. 63, č. 4 (2023), s. 1249-1259. ISSN 1549-9596. E-ISSN 1549-960X
R&D Projects: GA ČR(CZ) GJ19-22269Y
Institutional support: RVO:86652036
Keywords : CARBOXYPEPTIDASE-II * PHARMACOPHORE MODELS * POTENT INHIBITORS
OECD category: Analytical chemistry
Impact factor: 5.6, year: 2022
Method of publishing: Open access
https://pubs.acs.org/doi/10.1021/acs.jcim.2c01269
Permanent Link: https://hdl.handle.net/11104/0343285 - 2.0566024 - ÚOCHB 2023 RIV GB eng J - Journal Article
Jedličková, L. - Peterková, K. - Boateng, E. M. - Ulrychová, Lenka - Vacek, V. - Kutil, Zsofia - Jiang, Z. - Nováková, Zora - Šnajdr, Ivan - Kim, J. - O’Donoghue, A. J. - Bařinka, Cyril - Dvořák, Jan
Characterization of glutamate carboxypeptidase 2 orthologs in trematodes.
Parasites & Vectors. Roč. 15, č. 1 (2022), č. článku 480. ISSN 1756-3305. E-ISSN 1756-3305
R&D Projects: GA ČR(CZ) GA18-14167S; GA ČR(CZ) GJ19-22269Y
Institutional support: RVO:61388963 ; RVO:86652036
Keywords : platyhelminth * M28B metalloproteases * prostate specific-membrane antigen * Schistosoma mansoni * Fasciola hepatica * RNA in situ hybridization * folate hydrolase * immunohistochemistry * NAALADase
OECD category: Biochemistry and molecular biology
Impact factor: 3.2, year: 2022
Method of publishing: Open access
https://doi.org/10.1186/s13071-022-05556-5
Permanent Link: https://hdl.handle.net/11104/0337467 - 3.0552067 - ÚOCHB 2023 RIV US eng J - Journal Article
Bím, Daniel - Navrátil, Michal - Gutten, Ondrej - Konvalinka, Jan - Kutil, Zsofia - Culka, Martin - Navrátil, Václav - Alexandrova, A. N. - Bařinka, Cyril - Rulíšek, Lubomír
Predicting Effects of Site-Directed Mutagenesis on Enzyme Kinetics by QM/MM and QM Calculations: A Case of Glutamate Carboxypeptidase II.
Journal of Physical Chemistry B. Roč. 126, č. 1 (2022), s. 132-143. ISSN 1520-6106. E-ISSN 1520-5207
R&D Projects: GA MŠMT(CZ) LTAUSA19148; GA ČR(CZ) GA18-14167S; GA ČR(CZ) GJ19-22269Y
Institutional support: RVO:61388963 ; RVO:86652036
Keywords : monoamine-oxidase B * reaction mechanism * membrane antigen
OECD category: Physical chemistry
Impact factor: 3.3, year: 2022
Method of publishing: Limited access
https://doi.org/10.1021/acs.jpcb.1c09240
Permanent Link: http://hdl.handle.net/11104/0327224 - 4.0550559 - BTÚ 2022 RIV SE eng J - Journal Article
Temml, V. - Kutil, Zsofia
Structure-based molecular modeling in SAR analysis and lead optimization.
Computational and Structural Biotechnology Journal. Roč. 19, 2021-08-25 (2021), s. 1431-1444. ISSN 2001-0370. E-ISSN 2001-0370
R&D Projects: GA ČR(CZ) GJ19-22269Y
Institutional support: RVO:86652036
Keywords : Docking * Pharmacophore modeling * Lead optimization
OECD category: Biochemistry and molecular biology
Impact factor: 6.155, year: 2021
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S2001037021000696?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0329294 - 5.0534673 - BTÚ 2021 RIV US eng J - Journal Article
Kim, K. - Kwon, H. - Bařinka, Cyril - Motlová, Lucia - Nam, S. - Choi, D. - Ha, H. - Nam, H. - Son, S.-H. - Minn, I. - Pomper, M.G. - Yang, X. - Kutil, Zsofia - Byun, Y.
Novel beta- and gamma-Amino Acid-Derived Inhibitors of Prostate-Specific Membrane Antigen.
Journal of Medicinal Chemistry. Roč. 63, č. 6 (2020), s. 3261-3273. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR(CZ) GJ19-22269Y; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:86652036
Keywords : glutamate-carboxypeptidase-ii * urea-based inhibitors * preclinical evaluation * psma inhibitor * high-affinity
OECD category: Medicinal chemistry
Impact factor: 7.446, year: 2020
Method of publishing: Open access
https://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.9b02022
Permanent Link: http://hdl.handle.net/11104/0312850