Search results
- 1.0559439 - ÚMG 2023 RIV FR eng J - Journal Article
Gorecki, L. - Muthna, D. - Merdita, S. - Andrš, Martin - Kučera, T. - Havelek, R. - Mucková, L. - Kobrlová, T. - Soukup, J. - Krupa, P. - Prchal, L. - Soukup, O. - Roh, J. - Řezáčová, M. - Korábečný, J.
7-Azaindole, 2,7-diazaindole, and 1H-pyrazole as core structures for novel anticancer agents with potential chemosensitizing properties.
European Journal of Medicinal Chemistry. Roč. 240, June (2022), č. článku 114580. ISSN 0223-5234. E-ISSN 1768-3254
Institutional support: RVO:68378050
Keywords : ATR inhibition * Berzosertib * Cancer * Chemosensitization * Cytotoxicity * Glioblastoma
OECD category: Cell biology
Impact factor: 6.7, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/abs/pii/S0223523422004822?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0332860 - 2.0556370 - FGÚ 2023 RIV FR eng J - Journal Article
Jůza, R. - Vojtěchová, I. - Štefková-Mazochová, K. - Dehaen, W. - Petrásek, T. - Prchal, L. - Kobrlová, T. - Janoušek, J. - Vlček, P. - Mezeiová, E. - Svozil, D. - Zdarová Karasová, J. - Pejchal, J. - Stark, H. - Satala, G. - Bojarski, A. J. - Kubacka, M. - Mogilski, S. - Randáková, Alena - Musílek, K. - Soukup, O. - Korábečný, J.
Novel D-2/5-HT receptor modulators related to cariprazine with potential implication to schizophrenia treatment.
European Journal of Medicinal Chemistry. Roč. 232, Mar 15 (2022), č. článku 114193. ISSN 0223-5234. E-ISSN 1768-3254
Institutional support: RVO:67985823
Keywords : aripiprazole * cariprazine * dopamine type 2 receptor * drug development * serotonin receptor type 3 * schizophrenia * 1,4-Di-substituted aromatic piperazines * antipsychotic
OECD category: Pharmacology and pharmacy
Impact factor: 6.7, year: 2022
Method of publishing: Limited access
https://doi.org/10.1016/j.ejmech.2022.114193
Permanent Link: http://hdl.handle.net/11104/0330742 - 3.0546462 - FGÚ 2022 RIV CH eng J - Journal Article
Jůza, R. - Štefková, K. - Dehaen, W. - Randáková, Alena - Petrásek, T. - Vojtěchová, I. - Kobrlová, T. - Pulkrábková, L. - Mucková, L. - Mecava, M. - Prchal, L. - Mezeiová, E. - Musílek, K. - Soukup, O. - Korábečný, J.
Synthesis and In Vitro Evaluation of Novel Dopamine Receptor D-2 3,4-dihydroquinolin-2(1H)-one Derivatives Related to Aripiprazole.
Biomolecules. Roč. 11, č. 9 (2021), č. článku 1262. E-ISSN 2218-273X
Institutional support: RVO:67985823
Keywords : aripiprazole * dopamine receptor * blood–brain barrier * molecular modeling studies * schizophrenia
OECD category: Pharmacology and pharmacy
Impact factor: 6.064, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2218-273X/11/9/1262
Permanent Link: http://hdl.handle.net/11104/0322976 - 4.0541833 - ÚEM 2022 RIV CH eng J - Journal Article
Konečný, J. - Misiachna, Anna - Hrabinová, M. - Pulkrábková, L. - Benková, M. - Prchal, L. - Kučera, T. - Kobrlová, T. - Finger, V. - Kolcheva, Marharyta - Kortus, Štěpán - Jun, D. - Valko, M. - Horák, Martin - Soukup, O. - Korábečný, J.
Pursuing the Complexity of Alzheimer's Disease: Discovery of Fluoren-9-Amines as Selective Butyrylcholinesterase Inhibitors and N-Methyl-d-Aspartate Receptor Antagonists.
Biomolecules. Roč. 11, č. 1 (2021), č. článku 3. E-ISSN 2218-273X
R&D Projects: GA MZd(CZ) NU20-08-00296
Research Infrastructure: e-INFRA CZ - 90140
Institutional support: RVO:68378041
Keywords : acetylcholinesterase * Alzheimer´s disease * butyrylcholinesterase * fluorene * in vitro * in silico * multi-target directed ligands * N-methyl-d-aspartate receptor
OECD category: Pharmacology and pharmacy
Impact factor: 6.064, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2218-273X/11/1/3
Permanent Link: http://hdl.handle.net/11104/0319349 - 5.0541685 - FGÚ 2022 RIV CH eng J - Journal Article
Konečný, J. - Misiachna, Anna - Hrabinová, M. - Pulkrábková, L. - Benková, M. - Prchal, L. - Kučera, T. - Kobrlová, T. - Finger, V. - Kolcheva, Marharyta - Kortus, Štěpán - Jun, D. - Valko, M. - Horák, Martin - Soukup, O. - Korábečný, J.
Pursuing the Complexity of Alzheimer's Disease: Discovery of Fluoren-9-Amines as Selective Butyrylcholinesterase Inhibitors and N-Methyl-d-Aspartate Receptor Antagonists.
Biomolecules. Roč. 11, č. 1 (2021), č. článku 3. E-ISSN 2218-273X
Research Infrastructure: e-INFRA CZ - 90140
Institutional support: RVO:67985823
Keywords : acetylcholinesterase * Alzheimer´s disease * butyrylcholinesterase * fluorene * in vitro * in silico * multi-target directed ligands * N-methyl-d-aspartate receptor
OECD category: Pharmacology and pharmacy
Impact factor: 6.064, year: 2021
Method of publishing: Open access
https://www.mdpi.com/2218-273X/11/1/3
Permanent Link: http://hdl.handle.net/11104/0319216 - 6.0518489 - ÚEM 2020 RIV NL eng J - Journal Article
Kaniaková, Martina - Nepovímová, E. - Kletečková, L. - Skřenková, Kristýna - Holubová, K. - Chrienová, Z. - Hepnarová, V. - Kučera, T. - Kobrlová, T. - Valeš, K. - Korábečný, J. - Soukup, O. - Horák, Martin
Combination of Memantine and 6-Chlorotacrine as Novel Multi-Target Compound against Alzheimer's Disease.
Current Alzheimer Research. Roč. 16, č. 9 (2019), s. 821-833. ISSN 1567-2050. E-ISSN 1875-5828
Institutional support: RVO:68378041
Keywords : 6-Chlorotacrine * memantine * acetylcholinesterase
OECD category: Neurosciences (including psychophysiology
Impact factor: 3.047, year: 2019
Method of publishing: Limited access
http://www.eurekaselect.com/170309/article
Permanent Link: http://hdl.handle.net/11104/0303623 - 7.0511902 - FGÚ 2020 RIV NL eng J - Journal Article
Kaniaková, Martina - Nepovímová, E. - Kletečková, L. - Skřenková, K. - Holubová, K. - Chrienová, Z. - Hepnarová, V. - Kučera, T. - Kobrlová, T. - Valeš, K. - Korábečný, J. - Soukup, O. - Horák, Martin
Combination of Memantine and 6-Chlorotacrine as Novel Multi-Target Compound against Alzheimer's Disease.
Current Alzheimer Research. Roč. 16, č. 9 (2019), s. 821-833. ISSN 1567-2050. E-ISSN 1875-5828
R&D Projects: GA ČR(CZ) GA16-08554S
Institutional support: RVO:67985823
Keywords : 6-Chlorotacrine * Alzheimer´s disease * NMDA receptor * acetylcholinesterase * ion channel * memantine * patch-clamp technique
OECD category: Neurosciences (including psychophysiology
Impact factor: 3.047, year: 2019
Method of publishing: Limited access
http://www.eurekaselect.com/170309/article
Permanent Link: http://hdl.handle.net/11104/0302140 - 8.0504272 - FGÚ 2020 RIV US eng J - Journal Article
Nepovímová, E. - Janočková, J. - Misík, J. - Kubík, Štěpán - Stuchlík, Aleš - Valeš, Karel - Korábečný, J. - Mezeiová, E. - Doležal, R. - Soukup, O. - Kobrlová, T. - Pham, N. L. - Nguyen, T. D. - Konečný, J. - Kuča, K.
Orexin supplementation in narcolepsy treatment: A review.
Medicinal Research Reviews. Roč. 39, č. 3 (2019), s. 961-975. ISSN 0198-6325. E-ISSN 1098-1128
R&D Projects: GA ČR(CZ) GA17-08596S
Institutional support: RVO:67985823
Keywords : cell transplantation * gene therapy * hypocretin * narcolepsy * orexin * orexin agonists
OECD category: Pharmacology and pharmacy
Impact factor: 9.300, year: 2019
Method of publishing: Limited access
https://doi.org/10.1002/med.21550
Permanent Link: http://hdl.handle.net/11104/0295940