Search results
- 1.0585278 - MBÚ 2025 RIV NL eng J - Journal Article
Vrbata, David - Červený, Jakub - Kulik, Natalia - Hovorková, Michaela - Balogová, Soňa - Vlachová, Miluše - Pelantová, Helena - Křen, Vladimír - Bojarová, Pavla
Glycomimetic inhibitors of tandem-repeat galectins: Simple and efficient.
Bioorganic Chemistry. Roč. 145, April 24 (2024), č. článku 107231. ISSN 0045-2068. E-ISSN 1090-2120
R&D Projects: GA ČR(CZ) GA22-00262S; GA MŠMT(CZ) LUC23148
Research Infrastructure: e-INFRA CZ II - 90254
Institutional support: RVO:61388971
Keywords : carbohydrate-recognition * domain * lectin * oligosaccharide * optimization * expression * crystal * docking * Glycomimetic * Molecular modeling * Tandem-repeat galectin * Structure-affinity relationship * Thiodigalactoside
OECD category: Biochemistry and molecular biology
Impact factor: 5.1, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0045206824001366?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0353049 - 2.0575346 - ÚCHP 2024 RIV US eng J - Journal Article
Müllerová, Monika - Hovorková, Michaela - Závodná, Táňa - Červenková Šťastná, Lucie - Krupková, Alena - Hamala, Vojtěch - Nováková, Kateřina - Topinka, Jan - Bojarová, Pavla - Strašák, Tomáš
Lactose-Functionalized Carbosilane Glycodendrimers Are Highly Potent Multivalent Ligands for Galectin-9 Binding: Increased Glycan Affinity to Galectins Correlates with Aggregation Behavior.
Biomacromolecules. Roč. 24, č. 11 (2023), s. 4705-4717. ISSN 1525-7797. E-ISSN 1526-4602
R&D Projects: GA MŠMT(CZ) LTC19049; GA ČR(CZ) GA23-05146S; GA MŠMT(CZ) LM2018124; GA MŠMT(CZ) EF16_013/0001821
Institutional support: RVO:67985858 ; RVO:61388971 ; RVO:68378041 ; RVO:61388963
Keywords : polysaccharides * carbosilanes * glycodendrimers
OECD category: Organic chemistry; Biochemistry and molecular biology (UOCHB-X); Biochemistry and molecular biology (MBU-M); Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials (UEM-P)
Impact factor: 6.2, year: 2022
Method of publishing: Open access
https://pubs.acs.org/doi/10.1021/acs.biomac.3c00426
Permanent Link: https://hdl.handle.net/11104/0345132File Download Size Commentary Version Access müllerová-et-al-2023-lactose-functionalized-carbosilane-glycodendrimers-are-highly-potent-multivalent-ligands-for.pdf 2 3.1 MB Publisher’s postprint open-access - 3.0569335 - MBÚ 2024 RIV GB eng J - Journal Article
Konvalinková, Dorota - Dolníček, F. - Hovorková, Michaela - Červený, Jakub - Kundrát, O. - Pelantová, Helena - Petrásková, Lucie - Cvačka, Josef - Faizulina, M. - Varghese, B. - Kovaříček, P. - Křen, Vladimír - Lhoták, P. - Bojarová, Pavla
Glycocalix[4]arenes and their affinity to a library of galectins: the linker matters.
Organic & Biomolecular Chemistry. Roč. 21, č. 6 (2023), s. 1294-1302. ISSN 1477-0520. E-ISSN 1477-0539
R&D Projects: GA ČR(CZ) GA20-00215S; GA MŠMT(CZ) LTC20072
Institutional support: RVO:61388971 ; RVO:61388963
Keywords : upper rim * multivalent * lectins * glycoclusters * recognition * ligands * binding * conformations * glycoprotein * selectivity
OECD category: Biochemistry and molecular biology; Analytical chemistry (UOCHB-X)
Impact factor: 3.2, year: 2022
Method of publishing: Limited access
https://pubs.rsc.org/en/content/articlelanding/2023/OB/D2OB02235D
Permanent Link: https://hdl.handle.net/11104/0342522 - 4.0567424 - MBÚ 2024 RIV NL eng J - Journal Article
Hovorková, Michaela - Červený, Jakub - Bumba, Ladislav - Pelantová, Helena - Cvačka, Josef - Křen, Vladimír - Renaudet, O. - Goyard, D. - Bojarová, Pavla
Advanced high-affinity glycoconjugate ligands of galectins.
Bioorganic Chemistry. Roč. 131, February (2023), č. článku 106279. ISSN 0045-2068. E-ISSN 1090-2120
R&D Projects: GA ČR(CZ) GA22-00317S; GA MŠMT(CZ) LTC19038
Institutional support: RVO:61388971 ; RVO:61388963
Keywords : Biolayer interferometry * Carbohydrate * Click chemistry * Galectin * Glycoconjugate * Multivalency * Transglycosylation
OECD category: Biochemistry and molecular biology; Analytical chemistry (UOCHB-X)
Impact factor: 5.1, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S004520682200685X?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0342596 - 5.0557244 - MBÚ 2023 RIV CH eng J - Journal Article
Nekvasilová, Pavlína - Hovorková, Michaela - Mészáros, Zuzana - Petrásková, Lucie - Pelantová, Helena - Křen, Vladimír - Slámová, Kristýna - Bojarová, Pavla
Engineered Glycosidases for the Synthesis of Analogs of Human Milk Oligosaccharides.
International Journal of Molecular Sciences. Roč. 23, č. 8 (2022), č. článku 4106. E-ISSN 1422-0067
R&D Projects: GA MŠMT(CZ) LTC20072; GA MŠMT(CZ) LTC19035; GA ČR(CZ) GA20-00215S
EU Projects: European Commission(XE) CA18103
Institutional support: RVO:61388971
Keywords : beta-n-acetylhexosaminidase * crystal-structure * galactosidase * expression * lactose * cloning * glycosynthase * principle * gene * enzymatic synthesis * glycosidase * human milk oligosaccharide * mutagenesis
OECD category: Biochemistry and molecular biology
Impact factor: 5.6, year: 2022
Method of publishing: Open access
https://www.mdpi.com/1422-0067/23/8/4106
Permanent Link: http://hdl.handle.net/11104/0331292 - 6.0549199 - MBÚ 2022 RIV DE eng J - Journal Article
Hovorková, Michaela - Kulik, Natalia - Konvalinková, Dorota - Petrásková, Lucie - Křen, Vladimír - Bojarová, Pavla
Mutagenesis of Catalytic Nucleophile of beta-Galactosidase Retains Residual Hydrolytic Activity and Affords a Transgalactosidase.
ChemCatChem. Roč. 13, č. 21 (2021), s. 4532-4542. ISSN 1867-3880. E-ISSN 1867-3899
R&D Projects: GA ČR(CZ) GA20-00215S; GA MŠMT(CZ) LTC20072
Research Infrastructure: e-INFRA CZ - 90140
Institutional support: RVO:61388971
Keywords : glycosynthases * glycosidases * docking * Galactosidase * Glycosylation * Glycosynthase * Molecular Modeling * Site-Directed Mutagenesis
OECD category: Biochemistry and molecular biology
Impact factor: 5.501, year: 2021
Method of publishing: Limited access
https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/cctc.202101107
Permanent Link: http://hdl.handle.net/11104/0325223 - 7.0544845 - ÚCHP 2022 RIV DE eng J - Journal Article
Kurfiřt, Martin - Dračínský, Martin - Červenková Šťastná, Lucie - Cuřínová, Petra - Hamala, Vojtěch - Hovorková, Michaela - Bojarová, Pavla - Karban, Jindřich
Selectively Deoxyfluorinated N-Acetyllactosamine Analogues as 19F NMR Probes to Study Carbohydrate-Galectin Interactions.
Chemistry - A European Journal. Roč. 27, č. 51 (2021), s. 13040-13051. ISSN 0947-6539. E-ISSN 1521-3765
R&D Projects: GA MŠMT(CZ) LTC20052; GA ČR(CZ) GA20-01472S; GA MŠMT(CZ) LTC19038
EU Projects: European Commission(XE) CA17140 - COST Action
Institutional support: RVO:67985858 ; RVO:61388963 ; RVO:61388971
Keywords : carbohydrates * ELISA * galectins * NMR spectroscopy * T2 filter
OECD category: Organic chemistry; Physical chemistry (UOCHB-X); Biochemistry and molecular biology (MBU-M)
Impact factor: 5.020, year: 2021
Method of publishing: Limited access
Permanent Link: http://hdl.handle.net/11104/0321651File Download Size Commentary Version Access Selectively Deoxyfluorinated N-Acetyllactosamine Analogues.pdf 0 8.2 MB Publisher’s postprint require - 8.0544083 - MBÚ 2022 RIV FR eng J - Journal Article
Heine, Viktoria - Hovorková, Michaela - Vlachová, Miluše - Filipová, Marcela - Bumba, Ladislav - Janoušková, Olga - Hubálek, Martin - Cvačka, Josef - Petrásková, Lucie - Pelantová, Helena - Křen, Vladimír - Elling, L. - Bojarová, Pavla
Immunoprotective neo-glycoproteins: Chemoenzymatic synthesis of multivalent glycomimetics for inhibition of cancer-related galectin-3.
European Journal of Medicinal Chemistry. Roč. 220, AUG 5 2021 (2021), č. článku 113500. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA ČR(CZ) GA20-00215S; GA MŠMT(CZ) LTC19038; GA MŠMT(CZ) LTC18041; GA MŠMT(CZ) LM2018133
EU Projects: European Commission(XE) CA16225
Grant - others:AV ČR(CZ) DAAD-20-04
Program: Bilaterální spolupráce
Institutional support: RVO:61388971 ; RVO:61389013 ; RVO:61388963
Keywords : Cancer * Galectin-3 * Glycomimetic * Inhibition * Neo-glycoprotein
OECD category: Biochemistry and molecular biology; Polymer science (UMCH-V); Analytical chemistry (UOCHB-X)
Impact factor: 7.088, year: 2021
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0223523421003494?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0321173 - 9.0503890 - MBÚ 2020 RIV CH eng J - Journal Article
Bojarová, Pavla - Kulik, Natalia - Hovorková, Michaela - Slámová, Kristýna - Pelantová, Helena - Křen, Vladimír
The beta-N-Acetylhexosaminidase in the Synthesis of Bioactive Glycans: Protein and Reaction Engineering.
Molecules. Roč. 24, č. 3 (2019), č. článku 599. E-ISSN 1420-3049
R&D Projects: GA MŠMT(CZ) LTC18038
Institutional support: RVO:61388971
Keywords : beta-N-acetylhexosaminidase * galectin-3 * site-directed mutagenesis
OECD category: Biochemistry and molecular biology
Impact factor: 3.267, year: 2019
Method of publishing: Open access
https://www.mdpi.com/1420-3049/24/3/599
Permanent Link: http://hdl.handle.net/11104/0295661