Search results

  1. 1.
    0550096 - MBÚ 2022 RIV CH eng J - Journal Article
    Tvrdý, V. - Hrubša, M. - Jirkovský, E. - Biedermann, David - Kutý, M. - Valentová, Kateřina - Křen, Vladimír - Mladěnka, P.
    Silymarin dehydroflavonolignans chelate zinc and partially inhibit alcohol dehydrogenase.
    Nutrients. Roč. 13, č. 12 (2021), č. článku 4238. E-ISSN 2072-6643
    R&D Projects: GA ČR(CZ) GA18-00121S
    Institutional support: RVO:61388971
    Keywords : Alcohol dehydrogenase * Chelation * Dehydrosilybin * Docking * Flavonolignans * Glutamate dehydrogenase * Silybin * Zinc
    OECD category: Biochemistry and molecular biology
    Impact factor: 6.706, year: 2021
    Method of publishing: Open access
    https://www.mdpi.com/2072-6643/13/12/4238
    Permanent Link: http://hdl.handle.net/11104/0325947
     
     
  2. 2.
    0543521 - MBÚ 2022 RIV US eng J - Journal Article
    Tvrdý, V. - Pourová, J. - Jirkovský, E. - Křen, Vladimír - Valentová, Kateřina - Mladěnka, P.
    Systematic review of pharmacokinetics and potential pharmacokinetic interactions of flavonolignans from silymarin.
    Medicinal Research Reviews. Roč. 41, č. 4 (2021), s. 2195-2246. ISSN 0198-6325. E-ISSN 1098-1128
    R&D Projects: GA ČR(CZ) GA18-00121S
    Institutional support: RVO:61388971
    Keywords : absorption * excretion * interactions * metabolism * silybin
    OECD category: Pharmacology and pharmacy
    Impact factor: 12.388, year: 2021
    Method of publishing: Limited access
    https://onlinelibrary.wiley.com/doi/abs/10.1002/med.21791
    Permanent Link: http://hdl.handle.net/11104/0320713
     
     
  3. 3.
    0543091 - MBÚ 2022 RIV CH eng J - Journal Article
    Lomozová, Z. - Tvrdý, V. - Hrubša, M. - Catapano, M.C. - Macáková, K. - Biedermann, David - Kučera, R. - Křen, Vladimír - Mladěnka, P. - Valentová, Kateřina
    Dehydroflavonolignans from Silymarin Potentiate Transition Metal Toxicity In Vitro but Are Protective for Isolated Erythrocytes Ex Vivo.
    Antioxidants. Roč. 10, č. 5 (2021), č. článku 679. E-ISSN 2076-3921
    R&D Projects: GA ČR(CZ) GA18-00121S
    Institutional support: RVO:61388971
    Keywords : flavonolignans * silymarin * milk thistle * dehydroflavonolignans * dehydrosilybin * dehydrosilychristin * hydroxyl radical * iron * copper * prooxidation
    OECD category: Microbiology
    Impact factor: 7.675, year: 2021
    Method of publishing: Open access
    https://www.mdpi.com/2076-3921/10/5/679
    Permanent Link: http://hdl.handle.net/11104/0320379
     
     
  4. 4.
    0542509 - MBÚ 2022 RIV FR eng J - Journal Article
    Faisal, Z. - Mohos, V. - Fliszar-Nyul, E. - Valentová, Kateřina - Káňová, Kristýna - Lemli, B. - Kunsagi-Mate, S. - Poor, M.
    Interaction of silymarin components and their sulfate metabolites with human serum albumin and cytochrome P450 (2C9, 2C19, 2D6, and 3A4) enzymes.
    Biomedicine & Pharmacotherapy. Roč. 138, JUN 2021 (2021), č. článku 111459. ISSN 0753-3322. E-ISSN 1950-6007
    R&D Projects: GA ČR(CZ) GA18-00121S
    Institutional support: RVO:61388971
    Keywords : Silymarin * Sulfate conjugates * Human serum albumin * Cytochrome P450 * Pharmacokinetic interaction * Herb-drug interaction
    OECD category: Pharmacology and pharmacy
    Impact factor: 7.419, year: 2021
    Method of publishing: Open access
    https://www.sciencedirect.com/science/article/pii/S0753332221002444?via%3Dihub
    Permanent Link: http://hdl.handle.net/11104/0319906
     
     
  5. 5.
    0518345 - MBÚ 2020 RIV CH eng J - Journal Article
    Pourová, J. - Applová, L. - Macáková, K. - Vopršalová, M. - Migkos, T. - Bentanachs, R. - Biedermann, David - Petrásková, Lucie - Tvrdý, V. - Hrubša, M. - Karlíčková, J. - Křen, Vladimír - Valentová, Kateřina - Mladěnka, P.
    The effect of silymarin flavonolignans and their sulfated conjugates on platelet aggregation and blood vessels ex vivo.
    Nutrients. Roč. 11, č. 10 (2019), č. článku 2286. E-ISSN 2072-6643
    R&D Projects: GA ČR(CZ) GA18-00121S; GA MŠMT(CZ) LTC18003; GA MŠMT(CZ) LTC18071
    Institutional support: RVO:61388971
    Keywords : Silymarin * Milk Thiste * Flavonolignans
    OECD category: Cardiac and Cardiovascular systems
    Impact factor: 4.546, year: 2019
    Method of publishing: Open access
    https://www.mdpi.com/2072-6643/11/10/2286
    Permanent Link: http://hdl.handle.net/11104/0303506
    FileDownloadSizeCommentaryVersionAccess
    114_TheEffectOfSilymarinFlavonolignansAnd.pdf51 MBPublisher’s postprintrequire
     
     
  6. 6.
    0507895 - MBÚ 2020 RIV US eng J - Journal Article
    Begines, P. - Biedermann, David - Valentová, Kateřina - Petrásková, Lucie - Pelantová, Helena - Maya, I. - Fernandez-Bolanos, J.G. - Křen, Vladimír
    Chemoenzymatic Synthesis and Radical Scavenging of Sulfated Hydroxytyrosol, Tyrosol, and Acetylated Derivatives.
    Journal of Agricultural and Food Chemistry. Roč. 67, č. 26 (2019), s. 7281-7288. ISSN 0021-8561. E-ISSN 1520-5118
    R&D Projects: GA ČR(CZ) GA18-00121S; GA ČR(CZ) GA19-00043S
    Institutional support: RVO:61388971
    Keywords : olive phenols * arylsulfotransferase * hydroxytyrosol
    OECD category: Biochemistry and molecular biology
    Impact factor: 4.192, year: 2019
    Method of publishing: Limited access
    https://pubs.acs.org/doi/10.1021/acs.jafc.9b01065
    Permanent Link: http://hdl.handle.net/11104/0298855
    FileDownloadSizeCommentaryVersionAccess
    114_ChemoenzymaticSynthesisAndRadicalScavengingofSulfated.pdf3919.8 KBPublisher’s postprintrequire
     
     
  7. 7.
    0506716 - FGÚ 2020 RIV US eng J - Journal Article
    Plecitá-Hlavatá, Lydie - Engstová, Hana - Ježek, Jan - Holendová, Blanka - Tauber, Jan - Petrásková, Lucie - Křen, Vladimír - Ježek, Petr
    Potential of Mitochondria-Targeted Antioxidants to Prevent Oxidative Stress in Pancreatic beta-cells.
    Oxidative Medicine and Cellular Longevity. Roč. 2019, č. 2019 (2019), č. článku 1826303. ISSN 1942-0900. E-ISSN 1942-0994
    R&D Projects: GA ČR(CZ) GA16-06700S; GA ČR(CZ) GA17-01813S; GA ČR(CZ) GA18-00121S
    Institutional support: RVO:67985823 ; RVO:61388971
    Keywords : pancreatic beta cells * pancreatic islets * mitochondria- targeted antioxidants * oxidative stress * SkQ * S3QEL * S1QEL
    OECD category: Cell biology; Physiology (including cytology) (MBU-M)
    Impact factor: 5.076, year: 2019
    Method of publishing: Open access
    https://doi.org/10.1155/2019/1826303
    Permanent Link: http://hdl.handle.net/11104/0297909
     
     
  8. 8.
    0504552 - MBÚ 2020 RIV CH eng J - Journal Article
    De Bruyne, T. - Steenput, B. - Roth, L. - De Meyer, G.R.Y. - Nunes dos Santos, C. - Valentová, Kateřina - Dambrova, M . - Hermans, N.
    Dietary Polyphenols Targeting Arterial Stiffness: Interplay of Contributing Mechanisms and Gut Microbiome-Related Metabolism.
    Nutrients. Roč. 11, č. 3 (2019), č. článku 578. E-ISSN 2072-6643
    R&D Projects: GA ČR(CZ) GA18-00121S; GA MŠMT(CZ) LTC18003
    Institutional support: RVO:61388971
    Keywords : arterial stiffness * polyphenols * polyphenol biotransformation
    OECD category: Cardiac and Cardiovascular systems
    Impact factor: 4.546, year: 2019
    Method of publishing: Open access
    https://www.mdpi.com/2072-6643/11/3/578
    Permanent Link: http://hdl.handle.net/11104/0296158
     
     
  9. 9.
    0497478 - MBÚ 2019 RIV US eng J - Journal Article
    Tvrdý, V. - Catapano, M.C. - Rawlik, T. - Karlíčková, J. - Biedermann, David - Křen, Vladimír - Mladěnka, P. - Valentová, Kateřina
    Interaction of isolated silymarin flavonolignans with iron and copper.
    Journal of Inorganic Biochemistry. Roč. 189, DEC 2018 (2018), s. 115-123. ISSN 0162-0134. E-ISSN 1873-3344
    R&D Projects: GA ČR(CZ) GA18-00121S
    Institutional support: RVO:61388971
    Keywords : Silybin * Silychristin * Dehydrosilybin
    OECD category: Medicinal chemistry
    Impact factor: 3.224, year: 2018
    Permanent Link: http://hdl.handle.net/11104/0290043
     
     
  10. 10.
    0495022 - MBÚ 2019 RIV NL eng J - Journal Article
    Křen, Vladimír - Valentová, Kateřina
    Isoquercetin enzymatic production: A true story Response to the paper 'Zhua et al. [1]'.
    Molecular Catalysis. 458, Part A, October 2018 (2018), s. 112-114. ISSN 2468-8231. E-ISSN 2468-8231
    R&D Projects: GA MŠMT LTC17009; GA ČR(CZ) GA18-00121S
    Institutional support: RVO:61388971
    Keywords : RUTIN * BIOTRANSFORMATION * RHAMNOSIDASE
    OECD category: Bioprocessing technologies (industrial processes relying on biological agents to drive the process) biocatalysis, fermentation
    Impact factor: 2.938, year: 2018
    Permanent Link: http://hdl.handle.net/11104/0292368
     
     


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