Search results
- 1.0543164 - ÚOCHB 2022 RIV DE eng J - Journal Article
Kugler, Michael - Nekvinda, Jan - Holub, Josef - El Anwar, Suzan - Das, V. - Šícha, Václav - Pospíšilová, Klára - Fábry, M. - Král, V. - Brynda, Jiří - Kašička, Václav - Hajdúch, M. - Řezáčová, Pavlína - Grüner, Bohumír
Inhibitors of CA IX Enzyme Based on Polyhedral Boron Compounds.
Chembiochem. Roč. 22, č. 18 (2021), s. 2741-2761. ISSN 1439-4227. E-ISSN 1439-7633
R&D Projects: GA ČR(CZ) GA18-27648S; GA TA ČR(CZ) TE01020028; GA MŠMT(CZ) LM2015064
Institutional support: RVO:61388963 ; RVO:61388980
Keywords : carbonic anhydrase * carborane * cobalt bis(dicarbollide) * crystallography * enzyme inhibition * SAR studies
OECD category: Organic chemistry; Inorganic and nuclear chemistry (UACH-T)
Impact factor: 3.468, year: 2021
Method of publishing: Limited access
https://doi.org/10.1002/cbic.202100121
Permanent Link: http://hdl.handle.net/11104/0320438 - 2.0535986 - BFÚ 2021 RIV DE eng J - Journal Article
Fojt, Lukáš - Nekvinda, Jan - El Anwar, Suzan - Grüner, Bohumír - Havran, Luděk - Fojta, Miroslav
Simple Electrochemical Characterization of ortho-carborane and Some of its Exo-skeletal Derivatives.
Electroanalysis. Roč. 32, č. 8 (2020), s. 1859-1866. ISSN 1040-0397. E-ISSN 1521-4109
R&D Projects: GA ČR(CZ) GA19-04630S; GA ČR(CZ) GA18-27648S
Institutional support: RVO:68081707 ; RVO:61388980
Keywords : electrode * electrochemistry * carboranes * molecular sensors and probes * screen printed electrodes * glassy carbon electrode
OECD category: Analytical chemistry; Inorganic and nuclear chemistry (UACH-T)
Impact factor: 3.223, year: 2020
Method of publishing: Limited access
https://onlinelibrary.wiley.com/doi/full/10.1002/elan.202060038
Permanent Link: http://hdl.handle.net/11104/0313848 - 3.0534661 - ÚACH 2021 RIV DE eng J - Journal Article
Nekvinda, Jan - Kugler, Michael - Holub, Josef - El Anwar, Suzan - Brynda, Jiří - Pospíšilová, K. - Růžičková, Z. - Řezáčová, Pavlína - Grüner, Bohumír
Direct Introduction of an Alkylsulfonamido Group on C-sites of Isomeric Dicarba-closo-dodecaboranes: The Influence of Stereochemistry on Inhibitory Activity against the Cancer-Associated Carbonic Anhydrase IX Isoenzyme.
Chemistry - A European Journal. Roč. 26, č. 69 (2020), s. 16541-16553. ISSN 0947-6539. E-ISSN 1521-3765
R&D Projects: GA ČR(CZ) GA18-27648S; GA ČR(CZ) GA15-05677S
Grant - others:AV ČR(CZ) L200321851
Program: Program podpory perspektivníchlidských zdrojů - postdoktorandů
Institutional support: RVO:61388980 ; RVO:68378050
Keywords : medicinal chemistry * indomethacin * carbonic anhydrase * dicarba-closo-dodecaboranes * inhibitors * sulfonamide
OECD category: Inorganic and nuclear chemistry; Biochemistry and molecular biology (UMG-J)
Impact factor: 5.236, year: 2020
Method of publishing: Open access with time embargo
Permanent Link: http://hdl.handle.net/11104/0314883File Download Size Commentary Version Access Direct.pdf 2 1.8 MB Author’s postprint open-access Direct SI.pdf 0 5.2 MB Author’s postprint open-access - 4.0532715 - ÚOCHB 2021 RIV GB eng J - Journal Article
Kugler, Michael - Holub, Josef - Brynda, Jiří - Pospíšilová, Klára - El Anwar, Suzan - Bavol, Dmytro - Havránek, M. - Král, V. - Fábry, M. - Grüner, Bohumír - Řezáčová, Pavlína
The structural basis for the selectivity of sulfonamido dicarbaboranes toward cancer-associated carbonic anhydrase IX.
Journal of Enzyme Inhibition and Medicinal Chemistry. Roč. 35, č. 1 (2020), s. 1800-1810. ISSN 1475-6366. E-ISSN 1475-6374
R&D Projects: GA ČR(CZ) GA18-27648S; GA TA ČR(CZ) TE01020028; GA MŠMT(CZ) EF16_019/0000729
Grant - others:AV ČR(CZ) L200321851
Program: Program podpory perspektivníchlidských zdrojů - postdoktorandů
Institutional support: RVO:61388963 ; RVO:61388980
Keywords : carbonic anhydrase IX * carbone * enzyme inhibitors * sulfonamide * structure-activity relationship
OECD category: Biochemistry and molecular biology; Inorganic and nuclear chemistry (UACH-T)
Impact factor: 5.051, year: 2020
Method of publishing: Open access
https://doi.org/10.1080/14756366.2020.1816996
Permanent Link: http://hdl.handle.net/11104/0311123File Download Size Commentary Version Access The structural basis for the selectivity of sulfonamido dicarbaboranes toward cancer associated carbonic anhydrase IX.pdf 2 3.7 MB Publisher’s postprint open-access - 5.0532248 - ÚACH 2022 RIV DE eng J - Journal Article
Grüner, Bohumír - Kugler, Michael - El Anwar, Suzan - Holub, Josef - Nekvinda, Jan - Bavol, Dmytro - Růžičková, Z. - Pospíšilová, K. - Fábry, Milan - Král, Vlastimil - Brynda, Jiří - Řezáčová, P.
Cobalt Bis(dicarbollide) Alkylsulfonamides: Potent and Highly Selective Inhibitors of Tumor Specific Carbonic Anhydrase IX.
ChemPlusChem. Roč. 86, č. 3 (2021), s. 352-363. ISSN 2192-6506. E-ISSN 2192-6506
R&D Projects: GA ČR(CZ) GA18-27648S
Grant - others:AV ČR(CZ) L200321851
Program: Program podpory perspektivníchlidských zdrojů - postdoktorandů
Institutional support: RVO:61388980 ; RVO:68378050
Keywords : anti-tumor agents * carbonic anhydrase IX * carboranes * cobalt Bis(dicarbollide) * enzyme inhibitors
OECD category: Inorganic and nuclear chemistry; Human genetics (UMG-J)
Impact factor: 3.210, year: 2021
Method of publishing: Open access with time embargo
Permanent Link: http://hdl.handle.net/11104/0318394File Download Size Commentary Version Access Cobalt.pdf 0 1.9 MB Author’s postprint open-access Cobalt SI.pdf 0 5.5 MB Author’s postprint open-access - 6.0524603 - ÚOCHB 2021 RIV FR eng J - Journal Article
Dvořanová, J. - Kugler, Michael - Holub, Josef - Šícha, Václav - Das, V. - Nekvinda, Jan - El Anwar, Suzan - Havránek, M. - Pospíšilová, Klára - Fábry, M. - Král, V. - Medvedíková, M. - Matějková, Stanislava - Lišková, B. - Gurská, S. - Džubák, P. - Brynda, J. - Hajdúch, M. - Grüner, Bohumír - Řezáčová, Pavlína
Sulfonamido carboranes as highly selective inhibitors of cancer-specific carbonic anhydrase IX.
European Journal of Medicinal Chemistry. Roč. 200, Aug 15 (2020), č. článku 112460. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA ČR(CZ) GA18-27648S; GA ČR(CZ) GA15-05677S; GA TA ČR(CZ) TE01020028; GA MŠMT(CZ) LM2015064
Grant - others:AV ČR(CZ) L200321851
Program: Program podpory perspektivníchlidských zdrojů - postdoktorandů
Institutional support: RVO:61388963 ; RVO:61388980
Keywords : anti-tumor agents * carbonic anhydrase IX * carboranes * dicarbollide * enzyme inhibitors * drug penetration * multicellular spheroids
OECD category: Biochemistry and molecular biology; Inorganic and nuclear chemistry (UACH-T)
Impact factor: 6.514, year: 2020
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0223523420304311?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0308946 - 7.0523804 - ÚACH 2021 RIV CH eng J - Journal Article
Bakardjiev, Mario - El Anwar, Suzan - Bavol, Dmytro - Růžičková, Z. - Grüner, Bohumír
Focus on Chemistry of the 10-Dioxane-nido-7,8-dicarba-undecahydrido Undecaborate Zwitterion, Exceptionally Easy Abstraction of Hydrogen Bridge and Double-Action Pathways Observed in Ring Cleavage Reactions with OH- as Nucleophile.
Molecules. Roč. 25, č. 4 (2020), č. článku 814. E-ISSN 1420-3049
R&D Projects: GA ČR(CZ) GA18-27648S
Grant - others:AV ČR(CZ) L200321851
Program: Program podpory perspektivníchlidských zdrojů - postdoktorandů
Institutional support: RVO:61388980
Keywords : borane * carborane * dicarbollide ion * oxonium atom * nucleophilic substitution
OECD category: Inorganic and nuclear chemistry
Impact factor: 4.412, year: 2020
Method of publishing: Open access
Permanent Link: http://hdl.handle.net/11104/0308097File Download Size Commentary Version Access 0523804 SI.pdf 1 2.6 MB Other open-access Focus.pdf 1 1.6 MB CC-BY 4.0 licence Publisher’s postprint open-access
Research data: CCDC - 8.0520191 - ÚACH 2021 RIV US eng J - Journal Article
Nekvinda, Jan - Rozycka, D. - Rykowski, S. - Wyszko, E. - Fedoruk-Wyszomirska, A. - Gurda, D. - Orlicka-Plocka, M. - Giel-Pietraszuk, M. - Kiliszek, A. - Rypniewski, W. - Bachorz, R. - Wojcieszak, J. - Grüner, Bohumír - Olejniczak, A.
Synthesis of naphthalimide-carborane and metallacarborane conjugates: Anticancer activity, DNA binding ability.
Bioorganic Chemistry. Roč. 94, JAN (2020), č. článku 103432. ISSN 0045-2068. E-ISSN 1090-2120
R&D Projects: GA ČR(CZ) GA18-27648S
Institutional support: RVO:61388980
Keywords : Naphthalimides * Carborane * Metallacarborane * Anticancer activity
OECD category: Inorganic and nuclear chemistry
Impact factor: 5.275, year: 2020
Method of publishing: Open access with time embargo
Permanent Link: http://hdl.handle.net/11104/0304879File Download Size Commentary Version Access Synthesis.pdf 2 4.2 MB CC BY-NC-ND licence Author’s postprint open-access - 9.0511473 - ÚACH 2020 RIV US eng J - Journal Article
Grüner, Bohumír - Brynda, Jiří - Das, V. - Šícha, Václav - Štěpánková, J. - Nekvinda, Jan - Holub, Josef - Pospíšilová, B. - Fábry, Milan - Pachl, P. - Král, Vlastimil - Kugler, M. - Mašek, V. - Medvědiková, M. - Matějková, S. - Nová, A. - Lišková, B. - Gurská, S. - Džubák, P. - Hajdúch, M. - Řezáčová, Pavlína
Metallacarborane sulfamides: Unconventional, specific, and highly selective inhibitors of carbonic anhydrase IX.
Journal of Medicinal Chemistry. Roč. 62, č. 21 (2019), s. 9560-9575. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR(CZ) GA15-05677S; GA ČR(CZ) GA18-27648S
Institutional support: RVO:61388980 ; RVO:68378050
Keywords : Anti-tumor agents * Carbonic anhydrase IX * Cobaltacarborane inhibitors * Drug penetration * Multicellular spheroids
OECD category: Inorganic and nuclear chemistry; Medicinal chemistry (UMG-J)
Impact factor: 6.205, year: 2019
Method of publishing: Limited access
https://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.9b00945
Permanent Link: http://hdl.handle.net/11104/0302697