Search results
- 1.0585467 - MBÚ 2025 RIV NL eng J - Journal Article
Lepesheva, Anna - Grobarčíková, Michaela - Osičková, Adriana - Jurnečka, David - Knoblochová, Šárka - Čížková, Monika - Osička, Radim - Šebo, Peter - Mašín, Jiří
Modification of the RTX domain cap by acyl chains of adapted length rules the formation of functional hemolysin pores.
Biochimica Et Biophysica Acta-Biomembranes. Roč. 1866, č. 5 (2024), s. 184311. ISSN 0005-2736. E-ISSN 1879-2642
R&D Projects: GA ČR(CZ) GA22-15825S; GA ČR(CZ) GA22-01558S; GA ČR(CZ) GX19-27630X; GA MŠMT(CZ) LX22NPO5103; GA MŠMT(CZ) EH22_008/0004597
Research Infrastructure: EATRIS-CZ IV - 90253; CIISB III - 90242
Institutional support: RVO:61388971
Keywords : RTX toxin * Adenylate cyclase toxin * α-Hemolysin * Chimera * Fatty acylation * Cytotoxicity
OECD category: Microbiology
Impact factor: 3.4, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0005273624000427?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0353157File Download Size Commentary Version Access Modification of the RTX.pdf 2 3 MB Publisher’s postprint open-access
Research data: the ProteomeXchange Consortium via the PRIDE partner repository with the data set identifier PXD046160 - 2.0573968 - MBÚ 2024 RIV NL eng J - Journal Article
Osičková, Adriana - Knoblochová, Šárka - Bumba, Ladislav - Man, Petr - Kalaninová, Zuzana - Lepesheva, Anna - Jurnečka, David - Čížková, Monika - Biedermannová, Lada - Goldsmith, J. A. - Maynard, J. A. - McLellan, J. S. - Osička, Radim - Šebo, Peter - Mašín, Jiří
A conserved tryptophan in the acylated segment of RTX toxins controls their βinf2/inf integrin–independent cell penetration.
Journal of Biological Chemistry. Roč. 299, č. 8 (2023), č. článku 104978. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA ČR(CZ) GA22-01558S; GA ČR(CZ) GA22-01558S; GA MŠMT(CZ) LX22NPO5103; GA MŠMT(CZ) EF18_046/0015974; GA ČR(CZ) GX19-27630X
Research Infrastructure: e-INFRA CZ - 90140; EATRIS-CZ IV - 90253; CIISB III - 90242
Institutional support: RVO:61388971 ; RVO:86652036
Keywords : acylated segment * adenylate cyclase toxin * cytotoxicity * hydrogen/deuterium exchange * RTX toxin * thermal stability * tryptophan residue * α-hemolysin * β integrins 2
OECD category: Microbiology
Impact factor: 4.8, year: 2022
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0021925823020069?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0344352 - 3.0549727 - MBÚ 2022 RIV CH eng J - Journal Article
Holubová, Jana - Juhasz, Attila - Mašín, Jiří - Staněk, Ondřej - Jurnečka, David - Osičková, Adriana - Šebo, Peter - Osička, Radim
Selective enhancement of the cell-permeabilizing activity of adenylate cyclase toxin does not increase virulence of bordetella pertussis.
International Journal of Molecular Sciences. Roč. 22, č. 21 (2021), č. článku 11655. E-ISSN 1422-0067
R&D Projects: GA MŠMT(CZ) LM2018133; GA ČR(CZ) GA19-12695S
Research Infrastructure: CIISB II - 90127; CCP II - 90126
Institutional support: RVO:61388971
Keywords : Adenylate cyclase toxin * Bordetella pertussis * CAMP intoxication * Lung colonization * Lung inflammation * Pore-forming activity * RTX toxin * Virulence
OECD category: Microbiology
Impact factor: 6.208, year: 2021
Method of publishing: Open access
https://www.mdpi.com/1422-0067/22/21/11655
Permanent Link: http://hdl.handle.net/11104/0325678 - 4.0547497 - MBÚ 2022 RIV DE eng J - Journal Article
Lepesheva, Anna - Osičková, Adriana - Holubová, Jana - Jurnečka, David - Knoblochová, Šárka - Espinosa-Vinals, Carlos Angel - Bumba, Ladislav - Škopová, Karolína - Fišer, Radovan - Osička, Radim - Šebo, Peter - Mašín, Jiří
Different roles of conserved tyrosine residues of the acylated domains in folding and activity of RTX toxins.
Scientific Reports. Roč. 11, č. 1 (2021), č. článku 19814. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA MŠMT(CZ) LM2018133; GA ČR(CZ) GA19-12695S; GA ČR(CZ) GX19-27630X; GA ČR(CZ) GA19-04607S
Research Infrastructure: CIISB II - 90127
Institutional support: RVO:61388971
Keywords : adenylate-cyclase toxin * escherichia-coli hemolysin * bordetella-pertussis cyaa * cell-invasive activity * alpha-hemolysin * membrane translocation * complement receptor-3 * fatty-acylation * calcium * binding
OECD category: Biochemistry and molecular biology
Impact factor: 4.997, year: 2021
Method of publishing: Open access
https://www.nature.com/articles/s41598-021-99112-3
Permanent Link: http://hdl.handle.net/11104/0323712 - 5.0544756 - MBÚ 2022 RIV US eng J - Journal Article
Espinosa-Vinals, Carlos Angel - Mašín, Jiří - Holubová, Jana - Staněk, Ondřej - Jurnečka, David - Osička, Radim - Šebo, Peter - Bumba, Ladislav
Almost half of the RTX domain is dispensable for complement receptor 3 binding and cell-invasive activity of the Bordetella adenylate cyclase toxin.
Journal of Biological Chemistry. Roč. 297, č. 1 (2021), č. článku 100833. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA ČR(CZ) GA19-15175S; GA ČR(CZ) GA19-04607S; GA ČR(CZ) GX19-27630X; GA MŠMT(CZ) LM2018133
Institutional support: RVO:61388971
Keywords : identification * translocation * secretion * acylation * membrane * delivery
OECD category: Microbiology
Impact factor: 5.485, year: 2021
Method of publishing: Open access
https://www.webofscience.com/wos/woscc/full-record/WOS:000678068400033
Permanent Link: http://hdl.handle.net/11104/0321577 - 6.0537334 - MBÚ 2021 RIV US eng J - Journal Article
Novák, Jakub - Jurnečka, David - Linhartová, Irena - Holubová, Jana - Staněk, Ondřej - Štipl, Daniel - Dienstbier, Ana - Večerek, Branislav - Azevedo, N. - Provazník, J. - Beneš, V. - Šebo, Peter
A mutation upstream of the rpln-rpsd ribosomal operon downregulates bordetella pertussis virulence factor production without compromising bacterial survival within human macrophages.
mSystems. Roč. 5, č. 6 (2020), č. článku e00612-20. ISSN 2379-5077. E-ISSN 2379-5077
R&D Projects: GA ČR(CZ) GA19-12338S; GA MŠMT(CZ) LM2018133
Institutional support: RVO:61388971
Keywords : Bordetella Bronchiseptica * Pertussis Vaccine * Whooping Cough
OECD category: Microbiology
Impact factor: 6.496, year: 2020
Method of publishing: Open access
https://msystems.asm.org/content/5/6/e00612-20
Permanent Link: http://hdl.handle.net/11104/0315058 - 7.0533326 - MBÚ 2021 RIV US eng J - Journal Article
Osičková, Adriana - Khaliq, Humaira - Mašín, Jiří - Jurnečka, David - Suková, Anna - Fišer, Radovan - Holubová, Jana - Staněk, Ondřej - Šebo, Peter - Osička, Radim
Acyltransferase-mediated selection of the length of the fatty acyl chain and of the acylation site governs activation of bacterial RTX toxins.
Journal of Biological Chemistry. Roč. 295, č. 28 (2020), s. 9268-9280. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA MŠMT(CZ) LM2018127
Institutional support: RVO:61388971
Keywords : acylation * acyltransferase * cytotoxicit
OECD category: Microbiology
Impact factor: 5.157, year: 2020
Method of publishing: Open access
Permanent Link: http://hdl.handle.net/11104/0311734 - 8.0533321 - MBÚ 2021 RIV US eng J - Journal Article
Bayram, Jan - Malcová, Ivana - Sinkovec, Larisa - Holubová, Jana - Streparola, Gaia - Jurnečka, David - Kučera, Jan - Sedláček, Radislav - Šebo, Peter - Kamanová, Jana
Cytotoxicity of the effector protein BteA was attenuated in Bordetella pertussis by insertion of an alanine residue.
PLoS Pathogens. Roč. 16, č. 8 (2020), č. článku e1008512. ISSN 1553-7366. E-ISSN 1553-7374
R&D Projects: GA ČR(CZ) GJ18-16772Y; GA ČR(CZ) GX19-27630X; GA MŠMT(CZ) LM2018133; GA MŠMT(CZ) LM2015040; GA MŠMT ED2.1.00/19.0395
Research Infrastructure: CCP - 90040
Institutional support: RVO:61388971 ; RVO:68378050
Keywords : III SECRETION SYSTEM * PARAPERTUSSIS * BRONCHISEPTICA
OECD category: Microbiology; Microbiology (UMG-J)
Impact factor: 6.823, year: 2020
Method of publishing: Open access
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1008512
Permanent Link: http://hdl.handle.net/11104/0311731 - 9.0533031 - MBÚ 2021 RIV US eng J - Journal Article
Novák, Jakub - Fabrik, I. - Jurnečka, David - Holubová, Jana - Staněk, Ondřej - Šebo, Peter
Bordetella pertussis Acetylome is Shaped by Lysine Deacetylase Bkd1.
Journal of Proteome Research. Roč. 19, č. 9 (2020), s. 3680-3696. ISSN 1535-3893. E-ISSN 1535-3907
R&D Projects: GA ČR(CZ) GX19-27630X; GA ČR(CZ) GA18-20621S; GA MZd(CZ) NV16-28126A; GA MŠMT(CZ) LM2018133
Institutional support: RVO:61388971
Keywords : Bordetella pertussis * acetylome * KDAC * deacetylation
OECD category: Microbiology
Impact factor: 4.466, year: 2020
Method of publishing: Limited access
https://pubs.acs.org/doi/abs/10.1021/acs.jproteome.0c00178
Permanent Link: http://hdl.handle.net/11104/0311530 - 10.0533024 - MBÚ 2021 RIV US eng J - Journal Article
Mašín, Jiří - Osičková, Adriana - Jurnečka, David - Klímová, Nela - Khaliq, Humaira - Šebo, Peter - Osička, Radim
Retargeting from the CR3 to the LFA-1 receptor uncovers the adenylyl cyclase enzyme?translocating segment ofBordetellaadenylate cyclase toxin.
Journal of Biological Chemistry. Roč. 295, č. 28 (2020), s. 9349-9365. ISSN 0021-9258. E-ISSN 1083-351X
R&D Projects: GA ČR(CZ) GA19-04607S; GA ČR(CZ) GA18-18079S; GA ČR(CZ) GA19-12695S; GA ČR(CZ) GA18-20621S; GA MŠMT(CZ) LM2018133
Institutional support: RVO:61388971
Keywords : AC domain translocation * acylation * acyltransferase * fatty acyl * integrin * RTX toxin
OECD category: Microbiology
Impact factor: 5.157, year: 2020
Method of publishing: Open access with time embargo
https://www.jbc.org/content/early/2020/05/11/jbc.RA120.013630.short
Permanent Link: http://hdl.handle.net/11104/0311527