Search results
- 1.0588476 - ÚOCHB 2025 RIV CH eng J - Journal Article
Gorantla, S. P. - Prince, G. - Osius, J. - Dinesh, Dhurvas Chandrasekaran - Boddu, V. - Duyster, J. - von Bubnoff, N.
Type II mode of JAK2 inhibition and destabilization are potential therapeutic approaches against the ruxolitinib resistance driven myeloproliferative neoplasms.
Frontiers in Oncology. Roč. 14, July (2024), č. článku 1430833. ISSN 2234-943X. E-ISSN 2234-943X
R&D Projects: GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Keywords : myeloproliferative neoplasm * JAK2-V617F * ruxolitinib resistance * Hsp90 inhibitior * type I JAK2 inhibition
Impact factor: 3.5, year: 2023
Method of publishing: Open access
https://doi.org/10.3389/fonc.2024.1430833
Permanent Link: https://hdl.handle.net/11104/0355356File Download Size Commentary Version Access 10.3389fonc.2024.1430833.pdf 1 36.7 MB Publisher’s postprint open-access - 2.0570494 - ÚOCHB 2024 RIV GB eng J - Journal Article
Selvaraj, C. - Dinesh, Dhurvas Chandrasekaran - Pedone, E. M. - Alothaim, A. S. - Vijayakumar, R. - Rudhra, O. - Singh, S. K.
SARS-CoV-2 ORF8 dimerization and binding mode analysis with class I MHC: computational approaches to identify COVID-19 inhibitors.
Briefings in Functional Genomics. Roč. 22, č. 2 (2023), s. 227-240. ISSN 2041-2649. E-ISSN 2041-2657
Institutional support: RVO:61388963
Keywords : SARS-CoV-2 * ORF8 * SARS-CoV * dimer * disulfide bond * covid-19 * protein-protein interactions * molecular dynamics * MHC-1 * immune evasion * viral peptides
OECD category: Biochemistry and molecular biology
Impact factor: 2.5, year: 2023
Method of publishing: Limited access
https://doi.org/10.1093/bfgp/elac046
Permanent Link: https://hdl.handle.net/11104/0341789 - 3.0561949 - ÚOCHB 2023 RIV GB eng J - Journal Article
Hušková, Andrea - Dinesh, Dhurvas Chandrasekaran - Srb, Pavel - Bouřa, Evžen - Veverka, Václav - Šilhán, Jan
Model of abasic site DNA cross-link repair, from the architecture of NEIL3 DNA binding domains to the X-structure model.
Nucleic Acids Research. Roč. 50, č. 18 (2022), s. 10436-10448. ISSN 0305-1048. E-ISSN 1362-4962
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : covalent structure * crystal-structure * fanconis anemia
OECD category: Biochemistry and molecular biology
Impact factor: 14.9, year: 2022
Method of publishing: Open access
https://doi.org/10.1093/nar/gkac793
Permanent Link: https://hdl.handle.net/11104/0334376 - 4.0557947 - ÚOCHB 2023 RIV AE eng J - Journal Article
Selvaraj, C. - Dinesh, Dhurvas Chandrasekaran - Krafčíková, Petra - Bouřa, Evžen - Aarthy, M. - Pravin, M. A. - Singh, S. K.
Structural Understanding of SARS-CoV-2 Drug Targets, Active Site Contour Map Analysis and COVID-19 Therapeutics.
Current Molecular Pharmacology. Roč. 15, č. 2 (2022), s. 418-433. ISSN 1874-4672. E-ISSN 1874-4702
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : SARS-CoV-2 * COVID-19 * repurposing * FDA * drug targets * antivirales * active site * contour maps * medicinal plants * phytochemicals * TCM * natural products
OECD category: Virology
Impact factor: 2.7, year: 2022
Method of publishing: Limited access
https://doi.org/10.2174/1874467214666210906125959
Permanent Link: http://hdl.handle.net/11104/0331831 - 5.0544623 - ÚOCHB 2022 RIV GB eng J - Journal Article
Bera, K. - Jeba Reeda, V. S. - Rabila, P. R. - Dinesh, Dhurvas Chandrasekaran - Hritz, J. - Karthick, T.
An in silico molecular dynamics simulation study on the inhibitors of SARS-CoV-2 proteases (3CLpro and PLpro) to combat COVID-19.
Molecular Simulation. Roč. 47, č. 14 (2021), s. 1168-1184. ISSN 0892-7022. E-ISSN 1029-0435
Grant - others:AV ČR(CZ) L200551951
Research Infrastructure: e-INFRA CZ - 90140
Institutional support: RVO:61388963
Keywords : SARS-CoV-2 PLpro * SARS-CoV-2 3CLpro inhibitors * molecular docking * molecular dynamics simulation * MM/PBSA
OECD category: Biochemistry and molecular biology
Impact factor: 2.346, year: 2021
Method of publishing: Limited access
https://doi.org/10.1080/08927022.2021.1957884
Permanent Link: http://hdl.handle.net/11104/0321458 - 6.0544596 - ÚOCHB 2022 RIV US eng J - Journal Article
Selvaraj, C. - Dinesh, Dhurvas Chandrasekaran - Panwar, U. - Bouřa, Evžen - Singh, S. K.
High-Throughput Screening and Quantum Mechanics for Identifying Potent Inhibitors Against Mac1 Domain of SARS-CoV-2 Nsp3.
I E E E - A C M Transactions on Computational Biology and Bioinformatics. Roč. 18, č. 4 (2021), s. 1262-1270. ISSN 1545-5963. E-ISSN 1557-9964
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Grant - others:AV ČR(CZ) L200551951
Institutional support: RVO:61388963
Keywords : COVID-19 * Mac1 * Macro X * molecular dynamics * Nsp3 * quantum mechanics * SARS-CoV-2
OECD category: Biochemical research methods
Impact factor: 3.702, year: 2021
Method of publishing: Limited access
https://doi.org/10.1109/TCBB.2020.3037136
Permanent Link: http://hdl.handle.net/11104/0321439 - 7.0540951 - ÚOCHB 2022 RIV US eng J - Journal Article
Selvaraj, C. - Dinesh, Dhurvas Chandrasekaran - Panwar, U. - Abhirami, R. - Bouřa, Evžen - Singh, S. K.
Structure-based virtual screening and molecular dynamics simulation of SARS-CoV-2 Guanine-N7 methyltransferase (nsp14) for identifying antiviral inhibitors against COVID-19.
Journal of Biomolecular Structure & Dynamics. Roč. 39, č. 13 (2021), s. 4582-4593. ISSN 0739-1102. E-ISSN 1538-0254
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Grant - others:AV ČR(CZ) L200551951
Institutional support: RVO:61388963
Keywords : SARS-CoV-2 * nsp14 * N7-MTase * RNA capping * Methyltransferase * COVID-19 * TCM * natural products * molecular dynamics * ensemble sampling
OECD category: Biochemistry and molecular biology
Impact factor: 5.235, year: 2021
Method of publishing: Limited access
https://doi.org/10.1080/07391102.2020.1778535
Permanent Link: http://hdl.handle.net/11104/0318539 - 8.0539587 - ÚOCHB 2022 RIV CH eng J - Journal Article
Selvaraj, C. - Panwar, U. - Dinesh, Dhurvas Chandrasekaran - Bouřa, Evžen - Singh, P. - Dubey, V. K. - Singh, S. K.
Microsecond MD Simulation and Multiple-Conformation Virtual Screening to Identify Potential Anti-COVID-19 Inhibitors Against SARS-CoV-2 Main Protease.
Frontiers in Chemistry. Roč. 8, Jan 13 (2021), č. článku 595273. ISSN 2296-2646. E-ISSN 2296-2646
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Grant - others:AV ČR(CZ) L200551951
Institutional support: RVO:61388963
Keywords : SARS-CoV-2 main protease * COVID-19 * TCM * natural products * molecular dynamics * ensemble sampling
OECD category: Biochemistry and molecular biology
Impact factor: 5.545, year: 2021
Method of publishing: Open access
https://doi.org/10.3389/fchem.2020.595273
Permanent Link: http://hdl.handle.net/11104/0318116 - 9.0536797 - ÚOCHB 2021 RIV US eng J - Journal Article
Dinesh, Dhurvas Chandrasekaran - Chalupská, Dominika - Šilhán, Jan - Koutná, Eliška - Nencka, Radim - Veverka, Václav - Bouřa, Evžen
Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoprotein.
PLoS Pathogens. Roč. 16, č. 12 (2020), č. článku e1009100. ISSN 1553-7366. E-ISSN 1553-7374
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Grant - others:AV ČR(CZ) L200551951
Institutional support: RVO:61388963
Keywords : N-terminal domain * binding domain * crystal structure
OECD category: Biochemistry and molecular biology
Impact factor: 6.823, year: 2020
Method of publishing: Open access
https://doi.org/10.1371/journal.ppat.1009100
Permanent Link: http://hdl.handle.net/11104/0316257 - 10.0521343 - ÚOCHB 2021 RIV AE eng J - Journal Article
Dinesh, Dhurvas Chandrasekaran - Tamilarasan, S. - Rajaram, K. - Bouřa, Evžen
Antiviral Drug Targets of Single-Stranded RNA Viruses Causing Chronic Human Diseases.
Current Drug Targets. Roč. 21, č. 2 (2020), s. 105-124. ISSN 1389-4501. E-ISSN 1873-5592
R&D Projects: GA MŠMT(CZ) EF16_027/0008477; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : RNA viruses * chronic diseases * drug targets * inhibitors * antivirals * HIV * hepatitis * flaviviruses * protein structures
OECD category: Biochemistry and molecular biology
Impact factor: 3.465, year: 2020
Method of publishing: Limited access
https://www.eurekaselect.com/175035/article
Permanent Link: http://hdl.handle.net/11104/0305972