Search results
- 1.0584024 - ÚOCHB 2025 RIV US eng J - Journal Article
Selicharová, Irena - Fabre, Benjamin - Garre Hernández, María Soledad - Lubos, Marta - Pícha, Jan - Voburka, Zdeněk - Mitrová, Katarína - Jiráček, Jiří
Combinatorial libraries of bipodal binders of the insulin receptor.
ChemMedChem. (2024), e202400145. ISSN 1860-7179. E-ISSN 1860-7187
R&D Projects: GA MŠMT(CZ) LX22NPO5104; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : insulin * receptor * library * scaffold * peptide * combinatorial chemistry
OECD category: Medicinal chemistry
Impact factor: 3.4, year: 2022
Method of publishing: Open access
https://doi.org/10.1002/cmdc.202400145
Permanent Link: https://hdl.handle.net/11104/0352016File Download Size Commentary Version Access 10.1002cmdc.202400145.pdf 0 1.1 MB Publisher’s postprint open-access - 2.0583294 - ÚOCHB 2025 RIV NL eng J - Journal Article
Vetýšková, Veronika - Hubálek, Martin - Šulc, Josef - Procházka, Jan - Vondrášek, Jiří - Vydra Boušová, Kristýna
Proteolytic profiles of two isoforms of human AMBN expressed in E. coli by MMP-20 and KLK-4 proteases.
Heliyon. Roč. 10, č. 2 (2024), č. článku e24564. ISSN 2405-8440. E-ISSN 2405-8440
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : ameloblastin * MMP-20 * Ameloblastin * proteolytic analysis * KLK-4 * enzymatic cleavage products
Impact factor: 4, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.heliyon.2024.e24564
Permanent Link: https://hdl.handle.net/11104/0351295 - 3.0583040 - ÚOCHB 2025 RIV CH eng J - Journal Article
Brouns, T. - Lux, Vanda - Van Belle, S. - Christ, F. - Veverka, Václav - Debyser, Z.
The Impact of Lens Epithelium-Derived Growth Factor p75 Dimerization on Its Tethering Function.
Cells. Roč. 13, č. 3 (2024), č. článku 227. E-ISSN 2073-4409
R&D Projects: GA ČR(CZ) GA22-03028S; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : DNA-binding protein * protein-DNA interaction * protein-protein interaction * chromatin structure * protein dynamic * LEDGF/p75 * DNA-induced protein binding
Impact factor: 6, year: 2022
Method of publishing: Open access
https://doi.org/10.3390/cells13030227
Permanent Link: https://hdl.handle.net/11104/0351072 - 4.0580493 - BC 2024 RIV CH eng J - Journal Article
Martins, Larissa Almeida - Buša, Michal - Chlastáková, A. - Kotál, Jan - Beránková, Z. - Stergiou, N. - Jmel, Mohamed Amine - Schmitt, E. - Chmelař, J. - Mareš, Michael - Kotsyfakis, Michalis
Protease-bound structure of Ricistatin provides insights into the mechanism of action of tick salivary cystatins in the vertebrate host.
Cellular and Molecular Life Sciences. Roč. 80, č. 11 (2023), č. článku 339. ISSN 1420-682X. E-ISSN 1420-9071
R&D Projects: GA ČR(CZ) GA19-07247S; GA MŠMT(CZ) EF16_019/0000759; GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) LTAUSA19109
Institutional support: RVO:60077344 ; RVO:61388963
Keywords : ray crystal-structure * sialostatin-l * functional expression * cysteine cathepsins * mammalian legumain * ixodes-scapularis * inhibitors * stefin * generation * peptidase * Ixodes ricinus * Tick saliva * Cystatins * Protease inhibition * Protein structure * Host-parasite interactions
OECD category: Biochemistry and molecular biology; Biochemistry and molecular biology (UOCHB-X)
Impact factor: 8, year: 2022
Method of publishing: Limited access
https://link.springer.com/article/10.1007/s00018-023-04993-4
Permanent Link: https://hdl.handle.net/11104/0349268 - 5.0579941 - ÚOCHB 2024 RIV GB eng J - Journal Article
Faltejsková, Kateřina - Vondrášek, Jiří
PAPerFly: Partial Assembly-based Peak Finder for ab initio binding site reconstruction.
BMC Bioinformatics. Roč. 24, č. 1 (2023), č. článku 487. ISSN 1471-2105. E-ISSN 1471-2105
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Research Infrastructure: e-INFRA CZ - 90140
Institutional support: RVO:61388963
Keywords : ChIP-seq * DNA recognition * transcription factor * peak analysis * algorithm * graph theory
OECD category: Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)
Impact factor: 3, year: 2022
Method of publishing: Open access
https://doi.org/10.1186/s12859-023-05613-5
Permanent Link: https://hdl.handle.net/11104/0348738 - 6.0577780 - ÚOCHB 2024 RIV GB eng J - Journal Article
Kertisová, Anna - Žáková, Lenka - Macháčková, Kateřina - Marek, Aleš - Šácha, Pavel - Pompach, Petr - Jiráček, Jiří - Selicharová, Irena
Insulin receptor Arg717 and IGF-1 receptor Arg704 play a key role in ligand binding and in receptor activation.
Open Biology. Roč. 13, č. 11 (2023), č. článku 230142. E-ISSN 2046-2441
R&D Projects: GA MŠMT(CZ) LX22NPO5104; GA MŠMT(CZ) EF16_019/0000729; GA ČR(CZ) GA22-17978S; GA MŠMT(CZ) EF18_046/0015974; GA MŠMT LM2023042
Institutional support: RVO:61388963 ; RVO:86652036
Keywords : mutagenesisin vitro * peptide hormone * eceptor modification * eceptor tyrosine kinase * structure–function
OECD category: Biochemistry and molecular biology
Impact factor: 5.8, year: 2022
Method of publishing: Open access
https://doi.org/10.1098/rsob.230142
Permanent Link: https://hdl.handle.net/11104/0346886File Download Size Commentary Version Access 10.1098rsob.230142.pdf 2 2 MB Publisher’s postprint open-access - 7.0576137 - ÚOCHB 2024 RIV US eng J - Journal Article
Inniss, N. L. - Kozic, Ján - Li, F. - Rosas-Lemus, M. - Minasov, G. - Rybáček, Jiří - Zhu, Y. - Pohl, Radek - Shuvalova, L. - Rulíšek, Lubomír - Brunzelle, J. S. - Bednárová, Lucie - Štefek, Milan - Kormaník, Ján Michael - Andris, Erik - Šebestík, Jaroslav - Li, A. S. M. - Brown, P. J. - Schmitz, U. - Saikatendu, K. - Chang, E. - Nencka, Radim - Vedadi, M. - Satchell, K. J. F.
Discovery of a Druggable, Cryptic Pocket in SARS-CoV-2 nsp16 Using Allosteric Inhibitors.
ACS Infectious Diseases. Roč. 9, č. 10 (2023), s. 1918-1931. ISSN 2373-8227
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA MZd(CZ) NU20-05-00472
Institutional support: RVO:61388963
Keywords : coronavirus * NSP16 methyltransferase * covalent inhibitors * structural biology * antiviral
OECD category: Virology
Impact factor: 5.3, year: 2022
Method of publishing: Limited access
https://doi.org/10.1021/acsinfecdis.3c00203
Permanent Link: https://hdl.handle.net/11104/0345731 - 8.0575033 - ÚOCHB 2024 RIV US eng J - Journal Article
Koutná, Eliška - Lux, Vanda - Kouba, Tomáš - Škerlová, Jana - Nováček, J. - Srb, Pavel - Hexnerová, Rozálie - Šváchová, Hana - Kukačka, Zdeněk - Novák, Petr - Fábry, Milan - Poepsel, S. - Veverka, Václav
Multivalency of nucleosome recognition by LEDGF.
Nucleic Acids Research. Roč. 51, č. 18 (2023), s. 10011-10025. ISSN 0305-1048. E-ISSN 1362-4962
R&D Projects: GA ČR(CZ) GA22-03028S; GA ČR(CZ) GA22-27695S; GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) LO1304
Research Infrastructure: CIISB II - 90127; CIISB III - 90242
Institutional support: RVO:61388963 ; RVO:61388971
Keywords : PWWP domain * recombinant histones * structural basis
OECD category: Biochemistry and molecular biology; Biochemistry and molecular biology (MBU-M)
Impact factor: 14.9, year: 2022
Method of publishing: Open access
https://doi.org/10.1093/nar/gkad674
Permanent Link: https://hdl.handle.net/11104/0344870 - 9.0574400 - ÚOCHB 2024 RIV GB eng J - Journal Article
Potalitsyn, Pavlo - Mrázková, Lucie - Selicharová, Irena - Tencerová, Michaela - Ferenčáková, Michaela - Chrudinová, Martina - Turnovská, Tereza - Brzozowski, A. M. - Marek, Aleš - Kaminský, Jakub - Jiráček, Jiří - Žáková, Lenka
Non-glycosylated IGF2 prohormones are more mitogenic than native IGF2.
Communications Biology. Roč. 6, č. 1 (2023), č. článku 863. E-ISSN 2399-3642
R&D Projects: GA ČR(CZ) GA19-14069S; GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) LX22NPO5104
Institutional support: RVO:61388963 ; RVO:67985823
Keywords : hormone * prohormone * precursor * mitogenic * receptor * IGF
OECD category: Biochemistry and molecular biology
Impact factor: 5.9, year: 2022
Method of publishing: Open access
https://doi.org/10.1038/s42003-023-05239-6
Permanent Link: https://hdl.handle.net/11104/0344735File Download Size Commentary Version Access 10.1038s42003-023-05239-6.pdf 1 2.1 MB Publisher’s postprint open-access - 10.0574393 - ÚOCHB 2024 RIV GB eng J - Journal Article
Khoroshyy, Petro - Martinez-Seara, Hector - Myšková, J. - Lazar, Josef
Dynamics of transition dipole moment orientation in representative fluorescent proteins.
Physical Chemistry Chemical Physics. Roč. 25, č. 33 (2023), s. 22117-22123. ISSN 1463-9076. E-ISSN 1463-9084
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : quantitative analysis * anisotropy * FRET
OECD category: Physical chemistry
Impact factor: 3.3, year: 2022
Method of publishing: Open access
https://doi.org/10.1039/D3CP01242E
Permanent Link: https://hdl.handle.net/11104/0344721