Search results
- 1.0584812 - BTÚ 2025 RIV US eng J - Journal Article
Sychra, T. - Spalenkova, A. - Balatka, S. - Václavíková, R. - Šeborová, K. - Ehrlichová, M. - Truksa, Jaroslav - Sandoval-Acuna, Cristian - Němcová, V. - Szabo, A. - Kočí, K. - Tesarova, T. - Chen, L. - Ojima, I. - Oliverius, M. - Souček, P.
Third-generation taxanes SB-T-121605 and SB-T-121606 are effective in pancreatic ductal adenocarcinoma.
iScience. Roč. 27, č. 2 (2024), č. článku 109044. E-ISSN 2589-0042
R&D Projects: GA ČR(CZ) GA21-14082S
Institutional support: RVO:86652036
Keywords : biological evaluation * cancer * microenvironment * cytotoxicity * transport * design
OECD category: Biochemistry and molecular biology
Impact factor: 5.8, year: 2022
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S2589004224002657?via%3Dihub
Permanent Link: https://hdl.handle.net/11104/0352753 - 2.0565763 - BTÚ 2023 RIV CH eng J - Journal Article
Šeborová, K. - Koucká, K. - Spalenkova, A. - Holý, P. - Ehrlichová, M. - Sychra, T. - Chen, L. - Bendale, H. - Ojima, I. - Sandoval-Acuna, Cristian - Truksa, Jaroslav - Souček, P. - Václavíková, R.
Anticancer regimens containing third generation taxanes SB-T-121605 and SB-T-121606 are highly effective in resistant ovarian carcinoma model.
Frontiers in Pharmacology. Roč. 13, NOV 9 2022 (2022), č. článku 971905. ISSN 1663-9812. E-ISSN 1663-9812
R&D Projects: GA ČR(CZ) GA21-14082S
Institutional support: RVO:86652036
Keywords : ovarian carcinoma * resistance * paclitaxel * SB-T taxanes * efficacy * in vitro * in vivo
OECD category: Pharmacology and pharmacy
Impact factor: 5.6, year: 2022
Method of publishing: Open access
https://www.frontiersin.org/articles/10.3389/fphar.2022.971905/full
Permanent Link: https://hdl.handle.net/11104/0337429 - 3.0565700 - BTÚ 2023 RIV DE eng J - Journal Article
Nováková, Zora - Miloševič, Mirko - Kutil, Zsofia - Ondráková, Markéta - Havlínová, Barbora - Kašpárek, Petr - Sandoval-Acuna, Cristian - Korandová, Zuzana - Truksa, Jaroslav - Vrbacký, Marek - Rohlena, Jakub - Bařinka, Cyril
Generation and characterization of human U-2 OS cell lines with the CRISPR/Cas9-edited protoporphyrinogen oxidase IX gene.
Scientific Reports. Roč. 12, č. 1 (2022), č. článku 17081. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA MZd(CZ) NV17-32727A; GA ČR GA19-20553S; GA ČR(CZ) GA22-34507S; GA MŠMT(CZ) LM2018129; GA MŠMT(CZ) EF18_046/0016045
Institutional support: RVO:86652036 ; RVO:68378050 ; RVO:67985823
Keywords : DELTA-AMINOLEVULINATE SYNTHASE * VARIEGATE PORPHYRIA * MOLECULAR TARGET
OECD category: Cell biology
Impact factor: 4.6, year: 2022
Method of publishing: Open access
https://www.nature.com/articles/s41598-022-21147-x
Permanent Link: https://hdl.handle.net/11104/0337228 - 4.0548987 - BTÚ 2022 RIV US eng J - Journal Article
Sandoval-Acuna, Cristian - Torrealba, Natalia - Tomkova, Veronika - Jadhav, Sukanya B. - Blažková, Kristýna - Merta, L. - Lettlová, Sandra - Adamcová, Miroslava Kari - Rosel, D. - Brabek, J. - Neužil, Jiří - Štursa, Jan - Werner, Lukáš - Truksa, Jaroslav
Targeting Mitochondrial Iron Metabolism Suppresses Tumor Growth and Metastasis by Inducing Mitochondrial Dysfunction and Mitophagy.
Cancer Research. Roč. 81, č. 9 (2021), s. 2289-2303. ISSN 0008-5472. E-ISSN 1538-7445
R&D Projects: GA ČR(CZ) GA16-12816S; GA ČR(CZ) GA18-13103S; GA ČR(CZ) GC17-01192J; GA ČR(CZ) GA18-10832S
Institutional support: RVO:86652036 ; RVO:68378050
Keywords : sulfur cluster * cancer * biogenesis * breast * cells
OECD category: Oncology; Oncology (UMG-J)
Impact factor: 13.312, year: 2021
Method of publishing: Limited access
https://cancerres.aacrjournals.org/content/81/9/2289
Permanent Link: http://hdl.handle.net/11104/0325023 - 5.0536341 - BTÚ 2021 RIV CH eng J - Journal Article
Fuentes-Retamal, S. - Sandoval-Acuna, Cristian - Peredo-Silva, L. - Guzman-Rivera, D. - Pavani, M. - Torrealba, Natalia - Truksa, Jaroslav - Castro-Castillo, V. - Catalan, M. - Kemmerling, U. - Urra, F. A. - Ferreira, J.
Complex Mitochondrial Dysfunction Induced by TPP+-Gentisic Acid and Mitochondrial Translation Inhibition by Doxycycline Evokes Synergistic Lethality in Breast Cancer Cells.
Cells. Roč. 9, č. 2 (2020), č. článku 407. E-ISSN 2073-4409
Institutional support: RVO:86652036
Keywords : inhibition of the electron transport chain * inhibition of alpha-ketoglutarate dehydrogenase complex * mitochondrially targeted
OECD category: Cell biology
Impact factor: 6.600, year: 2020
Method of publishing: Open access
https://www.mdpi.com/2073-4409/9/2/407
Permanent Link: http://hdl.handle.net/11104/0314143 - 6.0520490 - BTÚ 2020 RIV US eng J - Journal Article
Tomkova, Veronika - Sandoval-Acuna, Cristian - Torrealba, Natalia - Truksa, Jaroslav
Mitochondrial fragmentation, elevated mitochondrial superoxide and respiratory supercomplexes disassembly is connected with the tamoxifen-resistant phenotype of breast cancer cells.
Free Radical Biology and Medicine. Roč. 143, NOV 1 2019 (2019), s. 510-521. ISSN 0891-5849. E-ISSN 1873-4596
R&D Projects: GA ČR(CZ) GA16-12816S; GA ČR(CZ) GA18-13103S; GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT(CZ) LQ1604
Institutional support: RVO:86652036
Keywords : activated protein-kinase * estrogen-receptor-alpha * acquired-resistance * Mitochondrial fragmentation * Reactive oxygen species
OECD category: Biochemistry and molecular biology
Impact factor: 6.170, year: 2019
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S0891584919310044?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0305193 - 7.0504151 - BTÚ 2020 RIV US eng J - Journal Article
Bajziková, Martina - Kovářová, Jaromíra - Coelho, Ana R. - Boukalová, Štěpána - Oh, S. - Rohlenová, Kateřina - Švec, David - Hubáčková, Soňa - Endaya, B. - Judasová, Kateřina - Bezawork-Geleta, A. - Klučková, Katarína - Chatre, L. - Zobalová, Renata - Nováková, Anna - Váňová, Kateřina - Ezrová, Zuzana - Maghzal, G. J. - Novais, Silvia Magalhaes - Olsinova, M. - Krobová, Linda - An, Y. J. - Davidová, Eliška - Nahácka, Zuzana - Sobol, Margaryta - Cunha-Oliveira, T. - Sandoval-Acuna, Cristian - Strnad, Hynek - Zhang, T. - Huynh, T. - Serafim, T. L. - Hozák, Pavel - Sardao, V. A. - Koopman, W. J. H. - Ricchetti, M. - Oliveira, P. J. - Kolář, František - Kubista, Mikael - Truksa, Jaroslav - Dvořáková-Hortová, Kateřina - Pacak, K. - Gürlich, R. - Stocker, R. - Zhou, Y. - Berridge, M.V. - Park, S. - Dong, L. - Rohlena, Jakub - Neužil, Jiří
Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells.
Cell Metabolism. Roč. 29, č. 2 (2019), s. 399-416. ISSN 1550-4131. E-ISSN 1932-7420
R&D Projects: GA ČR GA15-02203S; GA ČR GA16-12719S; GA ČR GA17-20904S; GA ČR GA16-22823S; GA ČR(CZ) GA16-12816S; GA ČR(CZ) GA18-11275S; GA ČR(CZ) GA18-02550S; GA MZd(CZ) NV16-31604A; GA MZd(CZ) NV17-30138A; GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) LM2015062; GA ČR(CZ) GJ18-24753Y; GA MŠMT(CZ) EF16_013/0001775
Institutional support: RVO:86652036 ; RVO:67985823 ; RVO:68378050
Keywords : ELECTRON-TRANSPORT CHAIN * PANCREATIC-CANCER * MITOCHONDRIA
OECD category: Cell biology; Physiology (including cytology) (FGU-C); Cell biology (UMG-J)
Impact factor: 21.567, year: 2019
Method of publishing: Open access
https://www.sciencedirect.com/science/article/pii/S1550413118306466?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0295861 - 8.0487179 - BTÚ 2019 RIV US eng J - Journal Article
Peredo-Silva, L. - Fuentes-Retamal, S. - Sandoval-Acuna, Cristian - Pavani, M. - Maya, J. D. - Castro-Castillo, V. - Madrid-Rojas, M. - Rebolledo, S. - Kemmerling, U. - Parra, E. - Ferreira, J.
Derivatives of alkyl gallate triphenylphosphonium exhibit antitumor activity in a syngeneic murine model of mammary adenocarcinoma.
Toxicology and Applied Pharmacology. Roč. 329, AUG 15 2017 (2017), s. 334-346. ISSN 0041-008X. E-ISSN 1096-0333
Institutional support: RVO:86652036
Keywords : Alkyl gallate triphenylphosphonium derivatives * Syngeneic murine model of breast cancer * Uncoupling of mitochondrial function
OECD category: Pharmacology and pharmacy
Impact factor: 3.616, year: 2017
Permanent Link: http://hdl.handle.net/11104/0291729