Search results
- 1.0533041 - FGÚ 2021 RIV US eng J - Journal Article
Ježek, Petr
2-Hydroxyglutarate in Cancer Cells.
Antioxidants & Redox Signaling. Roč. 33, č. 13 (2020), s. 903-926. ISSN 1523-0864. E-ISSN 1557-7716
R&D Projects: GA ČR(CZ) GA17-01813S
Institutional support: RVO:67985823
Keywords : 2-hydroxyglutarate * isocitrate dehydrogenase 1 and 2 * metabolic reprogramming in cancer * DNA and histone hypermethylation * metabolic marker
OECD category: Biochemistry and molecular biology
Impact factor: 8.401, year: 2020
Method of publishing: Open access
https://www.liebertpub.com/doi/10.1089/ars.2019.7902
Permanent Link: http://hdl.handle.net/11104/0311541 - 2.0532352 - FGÚ 2021 RIV US eng J - Journal Article
Plecitá-Hlavatá, Lydie - Engstová, Hana - Holendová, Blanka - Tauber, Jan - Špaček, Tomáš - Petrásková, Lucie - Křen, Vladimír - Špačková, Jitka - Gotvaldová, Klára - Ježek, Jan - Dlasková, Andrea - Smolková, Katarína - Ježek, Petr
Mitochondrial Superoxide Production Decreases on Glucose-Stimulated Insulin Secretion in Pancreatic beta Cells Due to Decreasing Mitochondrial Matrix NADH/NAD(+) Ratio.
Antioxidants & Redox Signaling. Roč. 33, č. 12 (2020), s. 789-815. ISSN 1523-0864. E-ISSN 1557-7716
R&D Projects: GA ČR(CZ) GA16-06700S; GA ČR(CZ) GA17-01813S; GA ČR(CZ) GA20-00408S
Institutional support: RVO:67985823 ; RVO:61388971
Keywords : mitochondrial superoxide generation * pancreatic beta cells * glucose-stimulated insulin secretion * Complex I * NADH/NAD(+) ratio * fluorescence lifetime imaging
OECD category: Endocrinology and metabolism (including diabetes, hormones); Analytical chemistry (MBU-M)
Impact factor: 8.401, year: 2020
Method of publishing: Open access
https://www.liebertpub.com/doi/10.1089/ars.2019.7800
Permanent Link: http://hdl.handle.net/11104/0310854 - 3.0531109 - FGÚ 2021 RIV US eng J - Journal Article
Plecitá-Hlavatá, Lydie - Jabůrek, Martin - Holendová, Blanka - Tauber, Jan - Pavluch, Vojtěch - Berková, Z. - Cahová, M. - Schröder, K. - Brandes, R. P. - Siemen, D. - Ježek, Petr
Glucose-Stimulated Insulin Secretion Fundamentally Requires H(2)O(2)Signaling by NADPH Oxidase 4.
Diabetes. Roč. 69, č. 7 (2020), s. 1341-1354. ISSN 0012-1797. E-ISSN 1939-327X
R&D Projects: GA ČR(CZ) GA20-00408S; GA ČR(CZ) GA16-06700S; GA ČR(CZ) GA17-01813S
Institutional support: RVO:67985823
Keywords : glucose-stimulated insulin secretion * NADPH oxidase NOX4 * ATP-sensitive potassium channel * cytosolic H2O2 redox signaling * beta-cell-specific NOX4 knockout mice * 2-oxo-isocaproate
OECD category: Endocrinology and metabolism (including diabetes, hormones)
Impact factor: 9.461, year: 2020
Method of publishing: Open access
https://doi.org/10.2337/db19-1130
Permanent Link: http://hdl.handle.net/11104/0309847 - 4.0531106 - FGÚ 2021 RIV CH eng J - Journal Article
Ježek, Petr - Holendová, Blanka - Plecitá-Hlavatá, Lydie
Redox Signaling from Mitochondria: Signal Propagation and Its Targets.
Biomolecules. Roč. 10, č. 1 (2020), č. článku 93. E-ISSN 2218-273X
R&D Projects: GA ČR(CZ) GA17-01813S
Institutional support: RVO:67985823
Keywords : redox signaling from mitochondria * mitochondrial superoxide formation * H2O2 diffusion * peroxiredoxins * HIF * redox-regulation of kinases
OECD category: Biochemistry and molecular biology
Impact factor: 4.879, year: 2020
Method of publishing: Open access
https://www.mdpi.com/2218-273X/10/1/93
Permanent Link: http://hdl.handle.net/11104/0309844 - 5.0531053 - FGÚ 2021 RIV GB eng J - Journal Article
Smolková, Katarína - Špačková, Jitka - Gotvaldová, Klára - Dvořák, Aleš - Křenková, Alena - Hubálek, Martin - Holendová, Blanka - Vítek, L. - Ježek, Petr
SIRT3 and GCN5L regulation of NADP plus - and NADPH-driven reactions of mitochondrial isocitrate dehydrogenase IDH2.
Scientific Reports. Roč. 10, č. 1 (2020), č. článku 8677. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA ČR(CZ) GA17-01813S; GA ČR(CZ) GA20-00408S
Research Infrastructure: CIISB - 90043
Institutional support: RVO:67985823 ; RVO:61388963
Keywords : IDH2 * SIRT3 * 2-hydroxyglutarate * 2HG * GCN5L * mitochondria * acetylation
OECD category: Biochemistry and molecular biology; Analytical chemistry (UOCHB-X)
Impact factor: 4.380, year: 2020
Method of publishing: Open access
https://doi.org/10.1038/s41598-020-65351-z
Permanent Link: http://hdl.handle.net/11104/0309806 - 6.0518635 - FGÚ 2020 RIV NL eng J - Journal Article
Ježek, Petr - Dlasková, Andrea
Dynamic of mitochondrial network, cristae, and mitochondrial nucleoids in pancreatic beta-cells.
Mitochondrion. Roč. 49, Nov (2019), s. 245-258. ISSN 1567-7249. E-ISSN 1872-8278
R&D Projects: GA ČR(CZ) GA17-08565S; GA ČR(CZ) GA17-01813S
Institutional support: RVO:67985823
Keywords : type 2 diabetes * mitochondrial network * mitochondrial cristae * mitochondrial nucleoids
OECD category: Endocrinology and metabolism (including diabetes, hormones)
Impact factor: 3.992, year: 2019
Method of publishing: Open access
https://doi.org/10.1016/j.mito.2019.06.007
Permanent Link: http://hdl.handle.net/11104/0303738 - 7.0510404 - FGÚ 2020 RIV US eng J - Journal Article
Ježek, Petr - Jabůrek, Martin - Plecitá-Hlavatá, Lydie
Contribution of Oxidative Stress and Impaired Biogenesis of Pancreatic beta-Cells to Type 2 Diabetes.
Antioxidants & Redox Signaling. Roč. 31, č. 10 (2019), s. 722-751. ISSN 1523-0864. E-ISSN 1557-7716
R&D Projects: GA ČR(CZ) GA16-06700S; GA ČR(CZ) GA17-01813S
Institutional support: RVO:67985823
Keywords : pancreatic beta-cells * type 2 diabetes * oxidative stress * impaired redox signaling * beta-cell identity self-checking * dedifferentiation
OECD category: Endocrinology and metabolism (including diabetes, hormones)
Impact factor: 7.040, year: 2019
Method of publishing: Open access
https://doi.org/10.1089/ars.2018.7656
Permanent Link: http://hdl.handle.net/11104/0300914 - 8.0506716 - FGÚ 2020 RIV US eng J - Journal Article
Plecitá-Hlavatá, Lydie - Engstová, Hana - Ježek, Jan - Holendová, Blanka - Tauber, Jan - Petrásková, Lucie - Křen, Vladimír - Ježek, Petr
Potential of Mitochondria-Targeted Antioxidants to Prevent Oxidative Stress in Pancreatic beta-cells.
Oxidative Medicine and Cellular Longevity. Roč. 2019, č. 2019 (2019), č. článku 1826303. ISSN 1942-0900. E-ISSN 1942-0994
R&D Projects: GA ČR(CZ) GA16-06700S; GA ČR(CZ) GA17-01813S; GA ČR(CZ) GA18-00121S
Institutional support: RVO:67985823 ; RVO:61388971
Keywords : pancreatic beta cells * pancreatic islets * mitochondria- targeted antioxidants * oxidative stress * SkQ * S3QEL * S1QEL
OECD category: Cell biology; Physiology (including cytology) (MBU-M)
Impact factor: 5.076, year: 2019
Method of publishing: Open access
https://doi.org/10.1155/2019/1826303
Permanent Link: http://hdl.handle.net/11104/0297909 - 9.0504243 - FGÚ 2020 RIV NL eng J - Journal Article
Ježek, Petr - Jabůrek, Martin - Porter, R. K.
Uncoupling mechanism and redox regulation of mitochondrial uncoupling protein 1 (UCP1).
Biochimica Et Biophysica Acta-Bioenergetics. Roč. 1860, č. 3 (2019), s. 259-269. ISSN 0005-2728. E-ISSN 1879-2650
R&D Projects: GA ČR(CZ) GA17-01813S; GA MŠMT(CZ) LTAUSA17174
Institutional support: RVO:67985823
Keywords : mitochondrial uncoupling protein1 * UCP1 * fatty acid cycling * brown adipose tissue * redox regulation
OECD category: Physiology (including cytology)
Impact factor: 3.465, year: 2019
Method of publishing: Open access
https://doi.org/10.1016/j.bbabio.2018.11.007
Permanent Link: http://hdl.handle.net/11104/0295921 - 10.0504242 - FGÚ 2020 RIV GB eng J - Journal Article
Ježek, Petr - Špaček, Tomáš - Tauber, Jan - Pavluch, Vojtěch
Mitochondrial Nucleoids: Superresolution microscopy analysis.
International Journal of Biochemistry and Cell Biology. Roč. 106, Jan (2019), s. 21-25. ISSN 1357-2725. E-ISSN 1878-5875
R&D Projects: GA ČR(CZ) GA16-04788S; GA ČR(CZ) GA17-01813S
Institutional support: RVO:67985823
Keywords : mtDNA * nucleoids * 3D superresolution microscopy * TFAM
OECD category: Cell biology
Impact factor: 3.673, year: 2019
Method of publishing: Limited access
https://doi.org/10.1016/j.biocel.2018.10.012
Permanent Link: http://hdl.handle.net/11104/0295920