Search results

  1. 1.
    0583323 - BTÚ 2025 RIV US eng J - Journal Article
    Nováková, Zora - Tehrani, Zahra Aliakbar - Jurok, R. - Motlová, Lucia - Kutil, Zsofia - Pavlíček, Jiří - Shukla, Shivam - Choy, C. J. - Havlínová, Barbora - Baranová, Petra - Berkman, C. E. - Kuchař, M. - Černý, Jiří - Bařinka, Cyril
    Structural, Biochemical, and Computational Characterization of Sulfamides as Bimetallic Peptidase Inhibitors.
    Journal of Chemical Information and Modeling. Roč. 64, č. 3 (2024), s. 1030-1042. ISSN 1549-9596. E-ISSN 1549-960X
    R&D Projects: GA MŠMT LX22NPO5102; GA MŠMT(CZ) LM2023055
    Institutional support: RVO:86652036
    Keywords : glutamate-carboxypeptidase-ii * carbonic-anhydrase inhibitors * membrane antigen * siderophore biosynthesis
    OECD category: Medicinal chemistry
    Impact factor: 5.6, year: 2022
    Method of publishing: Open access
    https://pubs.acs.org/doi/10.1021/acs.jcim.3c01542
    Permanent Link: https://hdl.handle.net/11104/0353346
     
     
  2. 2.
    0582381 - BTÚ 2024 GB eng J - Journal Article
    Panska, L. - Nedvedova, S. - Vacek, V. - Křivská, D. - Konečný, L. - Knop, F. - Kutil, Zsofia - Škultétyová, Ĺubica - Leontovyč, Adrian - Ulrychová, Lenka - Sakanari, J. - Asahina, M. - Bařinka, Cyril - Macurkova, M. - Dvořák, Jan
    Uncovering the essential roles of glutamate carboxypeptidase 2 orthologs in Caenorhabditis elegans.
    Bioscience Reports. Roč. 44, č. 1 (2024), č. článku BSR20230502. ISSN 0144-8463. E-ISSN 1573-4935
    R&D Projects: GA ČR(CZ) GA18-14167S
    Research Infrastructure: Czech-BioImaging II - 90129; Czech-BioImaging III - 90250
    Institutional support: RVO:86652036 ; RVO:61388963
    Keywords : amyotrophic-lateral-sclerosis * c-terminal domain * membrane antigen * n-acetylaspartylglutamate
    OECD category: Biochemistry and molecular biology
    Impact factor: 4, year: 2022
    Method of publishing: Open access
    https://portlandpress.com/bioscirep/article/44/1/BSR20230502/233851/Uncovering-the-essential-roles-of-glutamate
    Permanent Link: https://hdl.handle.net/11104/0350504
     
     
  3. 3.
    0574532 - BTÚ 2024 RIV US eng J - Journal Article
    Motlová, Lucia - Šnajdr, Ivan - Kutil, Zsofia - Andris, Erik - Ptáček, Jakub - Novotná, Adéla - Nováková, Zora - Havlínová, Barbora - Tueckmantel, W. - Dráberová, Helena - Majer, Pavel - Schutkowski, M. - Kozikowski, A. - Rulíšek, Lubomír - Bařinka, Cyril
    Comprehensive Mechanistic View of the Hydrolysis of Oxadiazole-Based Inhibitors by Histone Deacetylase 6 (HDAC6).
    ACS Chemical Biology. Roč. 18, č. 7 (2023), s. 1594-1610. ISSN 1554-8929. E-ISSN 1554-8937
    R&D Projects: GA ČR(CZ) GA21-31806S; GA ČR(CZ) GA23-05940S; GA MŠMT(CZ) LUAUS23247
    Research Infrastructure: CIISB III - 90242; EATRIS-CZ IV - 90253
    Institutional support: RVO:86652036 ; RVO:61388963
    Keywords : BASIS-SETS * COSMO * ENERGY * REFINEMENT
    OECD category: Biochemistry and molecular biology
    Impact factor: 4, year: 2022
    Method of publishing: Open access
    https://pubs.acs.org/doi/10.1021/acschembio.3c00212
    Permanent Link: https://hdl.handle.net/11104/0347139
     
     
  4. 4.
    0571548 - BTÚ 2024 RIV CH eng J - Journal Article
    Ptáček, Jakub - Šnajdr, Ivan - Schimer, Jiří - Kutil, Zsofia - Mikesova, Jana - Baranová, Petra - Havlínová, Barbora - Tueckmantel, W. - Majer, Pavel - Kozikowski, A. - Bařinka, Cyril
    Selectivity of Hydroxamate- and Difluoromethyloxadiazole-Based Inhibitors of Histone Deacetylase 6 In Vitro and in Cells.
    International Journal of Molecular Sciences. Roč. 24, č. 5 (2023), č. článku 4720. E-ISSN 1422-0067
    R&D Projects: GA ČR(CZ) GA21-31806S; GA MŠMT LX22NPO5102
    Institutional support: RVO:86652036 ; RVO:61388963
    Keywords : metallohydrolase * histone deacetylase * inhibitor profiling * tubulin * histone acetylation * nanoBRET
    OECD category: Biochemistry and molecular biology
    Impact factor: 5.6, year: 2022
    Method of publishing: Open access
    https://www.mdpi.com/1422-0067/24/5/4720
    Permanent Link: https://hdl.handle.net/11104/0342903
     
     
  5. 5.
    0571539 - BTÚ 2024 RIV US eng J - Journal Article
    Temml, V. - Kollar, J. - Schoenleitner, T. - Hoell, A. - Schuster, D. - Kutil, Zsofia
    Combination of In Silico and In Vitro Screening to Identify Novel Glutamate II Inhibitors.
    Journal of Chemical Information and Modeling. Roč. 63, č. 4 (2023), s. 1249-1259. ISSN 1549-9596. E-ISSN 1549-960X
    R&D Projects: GA ČR(CZ) GJ19-22269Y
    Institutional support: RVO:86652036
    Keywords : CARBOXYPEPTIDASE-II * PHARMACOPHORE MODELS * POTENT INHIBITORS
    OECD category: Analytical chemistry
    Impact factor: 5.6, year: 2022
    Method of publishing: Open access
    https://pubs.acs.org/doi/10.1021/acs.jcim.2c01269
    Permanent Link: https://hdl.handle.net/11104/0343285
     
     
  6. 6.
    0566024 - ÚOCHB 2023 RIV GB eng J - Journal Article
    Jedličková, L. - Peterková, K. - Boateng, E. M. - Ulrychová, Lenka - Vacek, V. - Kutil, Zsofia - Jiang, Z. - Nováková, Zora - Šnajdr, Ivan - Kim, J. - O’Donoghue, A. J. - Bařinka, Cyril - Dvořák, Jan
    Characterization of glutamate carboxypeptidase 2 orthologs in trematodes.
    Parasites & Vectors. Roč. 15, č. 1 (2022), č. článku 480. ISSN 1756-3305. E-ISSN 1756-3305
    R&D Projects: GA ČR(CZ) GA18-14167S; GA ČR(CZ) GJ19-22269Y
    Institutional support: RVO:61388963 ; RVO:86652036
    Keywords : platyhelminth * M28B metalloproteases * prostate specific-membrane antigen * Schistosoma mansoni * Fasciola hepatica * RNA in situ hybridization * folate hydrolase * immunohistochemistry * NAALADase
    OECD category: Biochemistry and molecular biology
    Impact factor: 3.2, year: 2022
    Method of publishing: Open access
    https://doi.org/10.1186/s13071-022-05556-5
    Permanent Link: https://hdl.handle.net/11104/0337467
     
     
  7. 7.
    0565700 - BTÚ 2023 RIV DE eng J - Journal Article
    Nováková, Zora - Miloševič, Mirko - Kutil, Zsofia - Ondráková, Markéta - Havlínová, Barbora - Kašpárek, Petr - Sandoval-Acuna, Cristian - Korandová, Zuzana - Truksa, Jaroslav - Vrbacký, Marek - Rohlena, Jakub - Bařinka, Cyril
    Generation and characterization of human U-2 OS cell lines with the CRISPR/Cas9-edited protoporphyrinogen oxidase IX gene.
    Scientific Reports. Roč. 12, č. 1 (2022), č. článku 17081. ISSN 2045-2322. E-ISSN 2045-2322
    R&D Projects: GA MZd(CZ) NV17-32727A; GA ČR GA19-20553S; GA ČR(CZ) GA22-34507S; GA MŠMT(CZ) LM2018129; GA MŠMT(CZ) EF18_046/0016045
    Institutional support: RVO:86652036 ; RVO:68378050 ; RVO:67985823
    Keywords : DELTA-AMINOLEVULINATE SYNTHASE * VARIEGATE PORPHYRIA * MOLECULAR TARGET
    OECD category: Cell biology
    Impact factor: 4.6, year: 2022
    Method of publishing: Open access
    https://www.nature.com/articles/s41598-022-21147-x
    Permanent Link: https://hdl.handle.net/11104/0337228
     
     
  8. 8.
    0556614 - BTÚ 2023 RIV US eng J - Journal Article
    Kutil, Zsofia - Meleshin, M. - Baranová, Petra - Havlínová, Barbora - Schutkowski, M. - Bařinka, Cyril
    Characterization of the class IIa histone deacetylases substrate specificity.
    FASEB Journal. Roč. 36, č. 5 (2022), č. článku e22287. ISSN 0892-6638. E-ISSN 1530-6860
    R&D Projects: GA ČR(CZ) GA21-31806S
    Institutional support: RVO:86652036
    Keywords : controls chondrocyte hypertrophy * catalytic-activity * acetylation * phosphorylation
    OECD category: Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology
    Impact factor: 4.8, year: 2022
    Method of publishing: Limited access
    https://faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202101663R
    Permanent Link: http://hdl.handle.net/11104/0332031
     
     
  9. 9.
    0552067 - ÚOCHB 2023 RIV US eng J - Journal Article
    Bím, Daniel - Navrátil, Michal - Gutten, Ondrej - Konvalinka, Jan - Kutil, Zsofia - Culka, Martin - Navrátil, Václav - Alexandrova, A. N. - Bařinka, Cyril - Rulíšek, Lubomír
    Predicting Effects of Site-Directed Mutagenesis on Enzyme Kinetics by QM/MM and QM Calculations: A Case of Glutamate Carboxypeptidase II.
    Journal of Physical Chemistry B. Roč. 126, č. 1 (2022), s. 132-143. ISSN 1520-6106. E-ISSN 1520-5207
    R&D Projects: GA MŠMT(CZ) LTAUSA19148; GA ČR(CZ) GA18-14167S; GA ČR(CZ) GJ19-22269Y
    Institutional support: RVO:61388963 ; RVO:86652036
    Keywords : monoamine-oxidase B * reaction mechanism * membrane antigen
    OECD category: Physical chemistry
    Impact factor: 3.3, year: 2022
    Method of publishing: Limited access
    https://doi.org/10.1021/acs.jpcb.1c09240
    Permanent Link: http://hdl.handle.net/11104/0327224
     
     
  10. 10.
    0551535 - BTÚ 2023 RIV US eng J - Journal Article
    Nováková, Zora - Mikesova, Jana - Ondráková, Markéta - Kutil, Zsofia - Veselá, K. - Martásek, P. - Bařinka, Cyril
    Molecular characterization of a novel His333Arg variant of human protoporphyrinogen oxidase IX.
    Biochemical and Biophysical Research Communications. Roč. 588, JAN 15 2022 (2022), s. 182-186. ISSN 0006-291X. E-ISSN 1090-2104
    R&D Projects: GA MZd(CZ) NV17-32727A
    Institutional support: RVO:86652036
    Keywords : variegate porphyria * structural insight * mutations * gene * Protoporphyrinogen oxidase IX
    OECD category: Biophysics
    Impact factor: 3.1, year: 2022
    Method of publishing: Open access
    https://www.sciencedirect.com/science/article/pii/S0006291X21016971?via%3Dihub
    Permanent Link: http://hdl.handle.net/11104/0327302
     
     

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