Search results
- 1.0550576 - BTÚ 2022 RIV US eng J - Journal Article
Shen, S. - Picci, C. - Ustinova, Kseniya - Benoy, V. - Kutil, Zsofia - Zhang, G. - Tavares, M. T. - Pavlíček, Jiří - Zimprich, Ch. A. - Robers, M. B. - Van den Bosch, L. - Bařinka, Cyril - Langley, B. - Kozikowski, A. P.
Tetrahydroquinoline-Capped Histone Deacetylase 6 Inhibitor SW-101 Ameliorates Pathological Phenotypes in a Charcot-Marie-Tooth Type 2A Mouse Model.
Journal of Medicinal Chemistry. Roč. 64, č. 8 (2021), s. 4810-4840. ISSN 0022-2623. E-ISSN 1520-4804
Institutional support: RVO:86652036
Keywords : hdac6 inhibitors * acetylation * disease * neuropathy
OECD category: Medicinal chemistry
Impact factor: 8.039, year: 2021
Method of publishing: Limited access
https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c02210
Permanent Link: http://hdl.handle.net/11104/0329546 - 2.0541383 - BTÚ 2021 RIV US eng J - Journal Article
Noonepalle, S. - Shen, S. - Ptáček, Jakub - Tavares, M. T. - Zhang, G. - Stránský, Jan - Pavlíček, Jiří - Ferreira, G. M. - Hadley, M. - Pelaez, G. - Bařinka, Cyril - Kozikowski, A. P. - Villagra, A.
Rational Design of Suprastat: A Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models.
Journal of Medicinal Chemistry. Roč. 63, č. 18 (2020), s. 10246-10262. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA MŠMT(CZ) LM2018127; GA ČR GA15-19640S; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:86652036
Keywords : antitumor-activity * force-field * hdac6 * acetylation * gromacs * charmm * implementation * metabolism * discovery * maps
OECD category: Medicinal chemistry
Impact factor: 7.446, year: 2020
Method of publishing: Open access
https://pubs.acs.org/doi/10.1021/acs.jmedchem.0c00567
Permanent Link: http://hdl.handle.net/11104/0318945 - 3.0510398 - BTÚ 2020 RIV US eng J - Journal Article
Shen, S. - Hadley, M. - Ustinova, Kseniya - Pavlíček, Jiří - Knox, T. - Noonepalle, S. - Tavares, M. T. - Zimprich, Ch. A. - Zhang, A. - Robers, M. B. - Bařinka, Cyril - Kozikowski, A. P. - Villagra, A.
Discovery of a New Isoxazole-3-hydroxamate-Based Histone Deacetylase 6 Inhibitor SS-208 with Antitumor Activity in Syngeneic Melanoma Mouse Models.
Journal of Medicinal Chemistry. Roč. 62, č. 18 (2019), s. 8557-8577. ISSN 0022-2623. E-ISSN 1520-4804
R&D Projects: GA ČR GA15-19640S; GA MŠMT(CZ) LM2015043; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:86652036
Keywords : HDAC6-SELECTIVE INHIBITORS * ACQUIRED-RESISTANCE * HDAC6 INHIBITOR
OECD category: Pharmacology and pharmacy
Impact factor: 6.205, year: 2019
Method of publishing: Open access
https://pubs.acs.org/doi/10.1021/acs.jmedchem.9b00946
Permanent Link: http://hdl.handle.net/11104/0300905 - 4.0480754 - BTÚ 2018 RIV US eng J - Journal Article
Tavares, M. T. - Shen, S. - Knox, T. - Hadley, M. - Kutil, Zsofia - Bařinka, Cyril - Villagra, A. - Kozikowski, A. P.
Synthesis and Pharmacological Evaluation of Selective Histone Deacetylase 6 Inhibitors in Melanoma Models.
ACS Medicinal Chemistry Letters. Roč. 8, č. 10 (2017), s. 1031-1036. ISSN 1948-5875
R&D Projects: GA ČR GA15-19640S; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:86652036
Keywords : HDAC6 inhibitors * nexturastat A * melanoma
OECD category: Biochemistry and molecular biology
Impact factor: 3.794, year: 2017
Permanent Link: http://hdl.handle.net/11104/0276455