Search results
- 1.0539841 - MBÚ 2021 RIV US eng J - Journal Article
Steiningerová, Lucie - Kameník, Zdeněk - Gažák, Radek - Kadlčík, Stanislav - Bashiri, G. - Man, Petr - Kuzma, Marek - Pavlíková, Magdaléna - Janata, Jiří
Different Reaction Specificities of F420H2-Dependent Reductases Facilitate Pyrrolobenzodiazepines and Lincomycin To Fit Their Biological Targets.
Journal of the American Chemical Society. Roč. 142, č. 7 (2020), s. 3440-3448. ISSN 0002-7863. E-ISSN 1520-5126
R&D Projects: GA ČR(CZ) GJ17-13436Y; GA MŠMT(CZ) ED1.1.00/02.0109; GA MŠMT(CZ) LQ1604
Research Infrastructure: CIISB - 90043
Institutional support: RVO:61388971
Keywords : antibody-drug conjugate * antitumor antibiotics * sequence-analysis * gene-cluster * biosynthesis * strain * lincosamides * tuberculosis * tomaymycin
OECD category: Microbiology
Impact factor: 15.419, year: 2020
Method of publishing: Limited access
https://pubs.acs.org/doi/abs/10.1021/jacs.9b11234
Permanent Link: http://hdl.handle.net/11104/0317538 - 2.0499560 - MBÚ 2019 RIV GB eng J - Journal Article
Janata, Jiří - Kameník, Zdeněk - Gažák, Radek - Kadlčík, Stanislav - Najmanová, Lucie
Biosynthesis and incorporation of an alkylproline-derivative (APD) precursor into complex natural products.
Natural Product Reports. Roč. 35, č. 3 (2018), s. 257-289. ISSN 0265-0568. E-ISSN 1460-4752
R&D Projects: GA ČR(CZ) GJ17-13436Y; GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:61388971
Keywords : synthetase adenylation domains * marine-derived actinomycete * peptidyl transferase center
OECD category: Microbiology
Impact factor: 11.876, year: 2018
Permanent Link: http://hdl.handle.net/11104/0291757File Download Size Commentary Version Access APD review published.pdf 12 4.3 MB Author´s preprint require - 3.0499534 - MBÚ 2019 RIV GB eng J - Journal Article
Kameník, Zdeněk - Gažák, Radek - Kadlčík, Stanislav - Steiningerová, Lucie - Rynd, Vít - Janata, Jiří
C-C bond cleavage in biosynthesis of 4-alkyl-L-proline precursors of lincomycin and anthramycin cannot precede C-methylation.
Nature Communications. Roč. 9, AUG 9 (2018), č. článku 3167. E-ISSN 2041-1723
R&D Projects: GA ČR(CZ) GJ17-13436Y
Institutional support: RVO:61388971
Keywords : Gene-cluster * Homolgy
OECD category: Microbiology
Impact factor: 11.878, year: 2018
Permanent Link: http://hdl.handle.net/11104/0291730File Download Size Commentary Version Access Kamenik_et_al-2018-Nature_Communications.pdf 7 1 MB Author´s preprint require - 4.0489915 - MBÚ 2019 RIV GB eng J - Journal Article
Pavlíková, Magdaléna - Kameník, Zdeněk - Janata, Jiří - Kadlčík, Stanislav - Kuzma, Marek - Najmanová, Lucie
Novel pathway of 3-hydroxyanthranilic acid formation in limazepine biosynthesis reveals evolutionary relation between phenazines and pyrrolobenzodiazepines.
Scientific Reports. Roč. 8, MAY17 (2018), č. článku 7810. ISSN 2045-2322. E-ISSN 2045-2322
R&D Projects: GA ČR(CZ) GJ17-13436Y; GA MŠMT(CZ) LQ1604; GA MŠMT(CZ) ED1.1.00/02.0109
Institutional support: RVO:61388971
Keywords : ANTIBODY-DRUG CONJUGATE * GENE-CLUSTER * PSEUDOMONAS-FLUORESCENS
OECD category: Microbiology
Impact factor: 4.011, year: 2018
Permanent Link: http://hdl.handle.net/11104/0284224File Download Size Commentary Version Access ASEP-2018-Pavlikova_publikace.pdf 4 2.9 MB Author´s preprint require - 5.0483944 - MBÚ 2018 RIV US eng J - Journal Article
Vobruba, Šimon - Kadlčík, Stanislav - Gažák, Radek - Janata, Jiří
Evolution-guided adaptation of an adenylation domain substrate specificity to an unusual amino acid.
PLoS ONE. Roč. 12, č. 12 (2017), č. článku e0189684. ISSN 1932-6203. E-ISSN 1932-6203
R&D Projects: GA ČR(CZ) GJ17-13436Y; GA MŠMT(CZ) LQ1604
Institutional support: RVO:61388971
Keywords : NONRIBOSOMAL PEPTIDE SYNTHETASES * BIOSYNTHETIC GENE-CLUSTER * LINCOSAMIDE ANTIBIOTICS
OECD category: Microbiology
Impact factor: 2.766, year: 2017
Permanent Link: http://hdl.handle.net/11104/0279118File Download Size Commentary Version Access 111_Evolution-guided adaptation of an adenylation domain substrat.pdf 8 1.6 MB Publisher’s postprint require - 6.0477899 - MBÚ 2018 RIV US eng J - Journal Article
Kameník, Zdeněk - Kadlčík, Stanislav - Gažák, Radek - Vobruba, Šimon - Palánová, Lucie - Kuzma, Marek - Janata, Jiří
Diversity of Alkylproline Moieties in Pyrrolobenzodiazepines Arises from Postcondensation Modifications of a Unified Building Block.
ACS Chemical Biology. Roč. 12, č. 8 (2017), s. 1993-1998. ISSN 1554-8929. E-ISSN 1554-8937
R&D Projects: GA ČR(CZ) GJ17-13436Y; GA MŠMT(CZ) LQ1604
Institutional support: RVO:61388971
Keywords : ANTIBODY-DRUG CONJUGATE * BIOSYNTHETIC GENE-CLUSTER * SEQUENCE-ANALYSIS
OECD category: Microbiology
Impact factor: 4.592, year: 2017
Permanent Link: http://hdl.handle.net/11104/0274106File Download Size Commentary Version Access Kamenik2017_APD in PBD_ACS chem biol.pdf 7 2 MB Publisher’s postprint require