Search results
- 1.0584489 - BFÚ 2024 RIV CZ eng J - Journal Article
Míčková, A. - Morong, M. - Levková, M. - Kurfurstova, D. - Kharaishvili, G. - Überall, I. - Študent, V. - Drápela, Stanislav - Souček, Karel - Bouchal, J.
Advantages and limitations of 3D organoids and ex vivo tumor tissue culture in personalized medicine for prostate cancer.
Klinická onkologie. Roč. 35, č. 6 (2022), s. 473-481. ISSN 0862-495X
Institutional support: RVO:68081707
Keywords : ex vivo tissue culture * organoids * personalized medicine * prostate cancer
OECD category: Oncology
Method of publishing: Open access
https://www.researchgate.net/publication/366322510_Advantages_and_limitations_of_3D_organoids_and_ex_vivo_tumor_tissue_culture_in_personalized_medicine_for_prostate_cancer
Permanent Link: https://hdl.handle.net/11104/0352404 - 2.0574949 - BFÚ 2024 RIV DE eng J - Journal Article
Kahounová, Zuzana - Pícková, Markéta - Drápela, Stanislav - Bouchal, J. - Szczyrbova, E. - Navrátil, J. - Souček, Karel
Circulating tumor cell-derived preclinical models: current status and future perspectives.
Cell Death & Disease. Roč. 14, č. 8 (2023), č. článku 530. ISSN 2041-4889. E-ISSN 2041-4889
R&D Projects: GA ČR(CZ) GA20-22984S; GA MZd(CZ) NU21-08-00023
Institutional support: RVO:68081707
Keywords : METASTATIC BREAST-CANCER * EX-VIVO CULTURE * PERIPHERAL-BLOOD
OECD category: Cell biology
Impact factor: 9, year: 2022
Method of publishing: Open access
https://www.nature.com/articles/s41419-023-06059-6
Permanent Link: https://hdl.handle.net/11104/0350472 - 3.0562613 - BFÚ 2023 RIV US eng J - Journal Article
Muresan, Ximena Maria - Slabáková, Eva - Procházková, Jiřina - Drápela, Stanislav - Fedr, Radek - Pícková, Markéta - Vacek, Antonín - Víchová, Ráchel - Suchánková, Tereza - Bouchal, J. - Kurfurstova, D. - Král, M. - Hulinova, T. - Sykora, R. - Študent, V. - Hejret, V. - van Weerden, W. - Puhr, M. - Pustka, V. - Potěšil, D. - Zdráhal, Z. - Culig, Z. - Souček, Karel
Toll-Like Receptor 3 Overexpression Induces Invasion of Prostate Cancer Cells, whereas Its Activation Triggers Apoptosis.
American Journal of Pathology. Roč. 192, č. 9 (2022), s. 1321-1335. ISSN 0002-9440. E-ISSN 1525-2191
Institutional support: RVO:68081707
Keywords : DOCETAXEL RESISTANCE * EPITHELIAL-CELLS * TUMOR-GROWTH
OECD category: Pathology
Impact factor: 6, year: 2022
Method of publishing: Limited access
https://doi.org/10.1016/j.ajpath.2022.05.009
Permanent Link: https://hdl.handle.net/11104/0340613 - 4.0556525 - BFÚ 2023 RIV NL eng J - Journal Article
Říhová, K. - Ducka, M. - Zambo, I. - Vymětalová, L. - Šrámek, M. - Trčka, F. - Verner, J. - Drápela, Stanislav - Fedr, Radek - Suchánková, Tereza - Pavlatovska, B. - Ondroušková, E. - Kubelkova, I. - Zapletalová, D. - Tucek, S. - Mudry, P. - Krakorova, D. - Knopfová, L. - Šmarda, J. - Souček, Karel - Borsig, L. - Beneš, P.
Transcription factor c-Myb: novel prognostic factor in osteosarcoma.
Clinical & Experimental Metastasis. Roč. 39, č. 2 (2022), s. 375-390. ISSN 0262-0898. E-ISSN 1573-7276
R&D Projects: GA ČR(CZ) GA20-22984S
Institutional support: RVO:68081707
Keywords : acute myeloid-leukemia * colorectal-cancer * down-regulation * expression * metastasis * stress
OECD category: Oncology
Impact factor: 4, year: 2022
Method of publishing: Limited access
https://link.springer.com/article/10.1007/s10585-021-10145-4
Permanent Link: https://hdl.handle.net/11104/0340442 - 5.0542177 - BFÚ 2022 RIV FR eng J - Journal Article
Němec, V. - Maier, L. - Berger, B.T. - Chaikuad, A. - Drápela, Stanislav - Souček, Karel - Knapp, S. - Paruch, K.
Highly selective inhibitors of protein kinases CLK and HIPK with the furo[3,2-b]pyridine core.
European Journal of Medicinal Chemistry. Roč. 215, APR 5 2021 (2021), č. článku 113299. ISSN 0223-5234. E-ISSN 1768-3254
Institutional support: RVO:68081707
Keywords : Kinase * Inhibitor * Furo[3,2-b]pyridine * hipk * mu135
OECD category: Pharmacology and pharmacy
Impact factor: 7.088, year: 2021
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/pii/S0223523421001483?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0319653 - 6.0534033 - BFÚ 2021 RIV NL eng J - Journal Article
Drápela, Stanislav - Khirsariya, P. - van Weerden, W. - Fedr, Radek - Suchánková, Tereza - Búzová, Diana - Červený, Jan - Hampl, A. - Puhr, M. - Watson, W. R. - Culig, Z. - Krejčí, L. - Paruch, K. - Souček, Karel
The CHK1 inhibitor MU380 significantly increases the sensitivity of human docetaxel-resistant prostate cancer cells to gemcitabine through the induction of mitotic catastrophe.
Molecular Oncology. Roč. 14, č. 10 (2020), s. 2487-2503. ISSN 1574-7891. E-ISSN 1878-0261
R&D Projects: GA MZd(CZ) NV18-08-00245; GA MZd(CZ) NV17-28518A
Institutional support: RVO:68081707 ; RVO:86652079
Keywords : dna-damage response * checkpoint kinase 1 * replication * initiation
OECD category: Plant sciences, botany; Plant sciences, botany (UEK-B)
Impact factor: 6.603, year: 2020
Method of publishing: Open access
https://febs.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/1878-0261.12756
Permanent Link: http://hdl.handle.net/11104/0312249 - 7.0524939 - BFÚ 2021 RIV CH eng J - Journal Article
Drápela, Stanislav - Bouchal, J. - Jolly, M. K. - Culig, Z. - Souček, Karel
ZEB1: A Critical Regulator of Cell Plasticity, DNA Damage Response, and Therapy Resistance.
Frontiers in molecular biosciences. Roč. 7, MAR 19 2020 (2020), č. článku 36. E-ISSN 2296-889X
R&D Projects: GA MZd(CZ) NV17-28518A; GA MZd(CZ) NV18-08-00245
Institutional support: RVO:68081707
Keywords : epithelial-mesenchymal-transition * negative breast-cancer * transcription factor * drug-resistance * prostate-cancer
OECD category: Biochemistry and molecular biology
Impact factor: 5.246, year: 2020
Method of publishing: Open access
https://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=AdvancedSearch&qid=8&SID=D4ZqAnHn6WSkCM83tcu&page=2&doc=20
Permanent Link: http://hdl.handle.net/11104/0309160 - 8.0523189 - BFÚ 2020 RIV IT eng J - Journal Article
Boudny, M. - Zemanová, J. - Khirsariya, P. - Borský, M. - Verner, J. - Černá, J. - Oltová, A. - Seda, V. - Mráz, M. - Jaros, J. - Jaskova, Z. - Spunarova, M. - Brychtová, Y. - Souček, Karel - Drápela, Stanislav - Kasparkova, M. - Mayer, J. - Paruch, K. - Trbusek, M.
Novel CHK1 inhibitor MU380 exhibits significant single-agent activity in TP53-mutated chronic lymphocytic leukemia cells.
Haematologica-The Hematology Journal. Roč. 104, č. 12 (2019), s. 2443-2455. ISSN 0390-6078
R&D Projects: GA MZd(CZ) NV15-33999A
Institutional support: RVO:68081707
Keywords : in-vitro * kinase * cll
OECD category: Hematology
Impact factor: 7.116, year: 2019
Method of publishing: Open access
http://www.haematologica.org/content/104/12/2443
Permanent Link: http://hdl.handle.net/11104/0307575 - 9.0501556 - BFÚ 2019 RIV DE eng J - Journal Article
Němec, V. - Hylsová, M. - Maier, L. - Flegel, J. - Sievers, S. - Ziegler, S. - Schroeder, M. - Berger, B.T. - Chaikuad, A. - Valčíková, B. - Uldrijan, S. - Drápela, Stanislav - Souček, Karel - Waldmann, H. - Knapp, S. - Paruch, K.
Furo[3,2-b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway.
Angewandte Chemie - International Edition. Roč. 58, č. 4 (2019), s. 1062-1066. ISSN 1433-7851. E-ISSN 1521-3773
Institutional support: RVO:68081707
Keywords : small-molecule * discovery * purine
OECD category: Biochemistry and molecular biology
Impact factor: 12.959, year: 2019
Method of publishing: Limited access
https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201810312
Permanent Link: http://hdl.handle.net/11104/0293565 - 10.0485556 - BFÚ 2018 RIV US eng J - Journal Article
Samadder, P. - Suchánková, Tereza - Hylse, O. - Khirsariya, P. - Nikulenkov, F. - Drápela, Stanislav - Straková, Nicol - Vaňhara, P. - Vašíčková, K. - Kolářová, H. - Binó, Lucia - Bittová, M. - Ovesná, P. - Kollár, P. - Fedr, Radek - Esner, M. - Jaros, J. - Hampl, A. - Krejčí, L. - Paruch, K. - Souček, Karel
Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation.
Molecular Cancer Therapeutics. Roč. 16, č. 9 (2017), s. 1831-1842. ISSN 1535-7163. E-ISSN 1538-8514
R&D Projects: GA MZd(CZ) NV15-33999A
Institutional support: RVO:68081707
Keywords : therapeutic-efficacy * protein-kinases * targeting chk1 * cancer-therapy
OECD category: Oncology
Impact factor: 5.365, year: 2017
Permanent Link: http://hdl.handle.net/11104/0280521