Search results
- 1.0569310 - BFÚ 2024 RIV DE eng J - Journal Article
Szczepanik, P. M. - Mikhaylov, A. A. - Hylse, O. - Kučera, R. - Daďová, Petra - Nečas, M. - Kubala, Lukáš - Paruch, K. - Svenda, J.
Convergent Assembly of the Tricyclic Labdane Core Enables Synthesis of Diverse Forskolin-like Molecules.
Angewandte Chemie - International Edition. Roč. 62, č. 1 (2023), č. článku e202213183. ISSN 1433-7851. E-ISSN 1521-3773
Institutional support: RVO:68081707
Keywords : Convergent Synthesis * Forskolin * Labdanes * Michael Addition * Olefin Metathesis
OECD category: Organic chemistry
Impact factor: 16.6, year: 2022
Method of publishing: Open access
https://onlinelibrary.wiley.com/doi/10.1002/anie.202213183
Permanent Link: https://hdl.handle.net/11104/0345676 - 2.0506414 - BFÚ 2020 RIV US eng J - Journal Article
Zemanová, J. - Hylse, O. - Collakova, J. - Veselý, P. - Oltová, A. - Borský, M. - Zaprazna, K. - Kasparkova, M. - Janovská, P. - Verner, J. - Kohoutek, J. - Dzimkova, M. - Bryja, Vítězslav - Jaskova, Z. - Brychtová, Y. - Paruch, K. - Trbušek, M.
Chk1 inhibition significantly potentiates activity of nucleoside analogs in TP53-mutated B-lymphoid cells.
OncoTarget. Roč. 7, č. 38 (2016), s. 62091-62106. ISSN 1949-2553
R&D Projects: GA MZd(CZ) NV15-33999A
Institutional support: RVO:68081707
Keywords : chronic lymphocytic-leukemia * checkpoint kinase 1 * dna-damage * cancer-cells
OECD category: Cell biology
Impact factor: 5.168, year: 2016
Method of publishing: Open access
http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=11388&path%5B%5D=36488
Permanent Link: http://hdl.handle.net/11104/0297664 - 3.0485556 - BFÚ 2018 RIV US eng J - Journal Article
Samadder, P. - Suchánková, Tereza - Hylse, O. - Khirsariya, P. - Nikulenkov, F. - Drápela, Stanislav - Straková, Nicol - Vaňhara, P. - Vašíčková, K. - Kolářová, H. - Binó, Lucia - Bittová, M. - Ovesná, P. - Kollár, P. - Fedr, Radek - Esner, M. - Jaros, J. - Hampl, A. - Krejčí, L. - Paruch, K. - Souček, Karel
Synthesis and Profiling of a Novel Potent Selective Inhibitor of CHK1 Kinase Possessing Unusual N-trifluoromethylpyrazole Pharmacophore Resistant to Metabolic N-dealkylation.
Molecular Cancer Therapeutics. Roč. 16, č. 9 (2017), s. 1831-1842. ISSN 1535-7163. E-ISSN 1538-8514
R&D Projects: GA MZd(CZ) NV15-33999A
Institutional support: RVO:68081707
Keywords : therapeutic-efficacy * protein-kinases * targeting chk1 * cancer-therapy
OECD category: Oncology
Impact factor: 5.365, year: 2017
Permanent Link: http://hdl.handle.net/11104/0280521 - 4.0485514 - BFÚ 2018 RIV DE eng J - Journal Article
Hylse, O. - Maier, L. - Kučera, R. - Perečko, Tomáš - Svobodová, Aneta - Kubala, Lukáš - Paruch, K. - Svenda, J.
A Concise Synthesis of Forskolin.
Angewandte Chemie - International Edition. Roč. 56, č. 41 (2017), s. 12586-12589. ISSN 1433-7851. E-ISSN 1521-3773
Institutional support: RVO:68081707
Keywords : adenylyl-cyclase isoforms * key intermediate * enantioselective route
OECD category: Biochemistry and molecular biology
Impact factor: 12.102, year: 2017
Permanent Link: http://hdl.handle.net/11104/0280506 - 5.0476449 - BFÚ 2018 RIV US eng J - Journal Article
Maier, L. - Khirsariya, P. - Hylse, O. - Adla, S.K. - Cernova, L. - Poljak, M. - Krajčovičová, S. - Weis, E. - Drápela, Stanislav - Souček, Karel - Paruch, K.
Diastereoselective Flexible Synthesis of Carbocyclic C-Nucleosides.
Journal of Organic Chemistry. Roč. 82, č. 7 (2017), s. 3382-3402. ISSN 0022-3263. E-ISSN 1520-6904
Institutional support: RVO:68081707
Keywords : mitsunobu * catalysis * alcohols
OECD category: Organic chemistry
Impact factor: 4.805, year: 2017
Permanent Link: http://hdl.handle.net/11104/0272947