Search results
- 1.0587162 - ÚMG 2025 RIV GB eng J - Journal Article
Řehulka, J. - Jurášek, M. - Dráber, Pavel - Ivanová, A. - Gurská, S. - Ječmenová, K. - Mokshyna, Olena - Hajdúch, M. - Polishchuk, P. - Drašar, P. B. - Džubák, P.
Click estradiol dimers with novel aromatic bridging units: synthesis and anticancer evaluation.
Journal of Enzyme Inhibition and Medicinal Chemistry. Roč. 39, č. 1 (2024), s. 2367139. ISSN 1475-6366. E-ISSN 1475-6374
R&D Projects: GA MŠMT LM2023052; GA MŠMT(CZ) LM2023053; GA MŠMT LX22NPO5102
Institutional support: RVO:68378050 ; RVO:61388963
Keywords : estradiol dimers * EDs variants * structural modification
OECD category: Biochemistry and molecular biology
Impact factor: 5.6, year: 2022
Method of publishing: Open access
https://www.tandfonline.com/doi/full/10.1080/14756366.2024.2367139
Permanent Link: https://hdl.handle.net/11104/0354427File Download Size Commentary Version Access Řehulka et al. EIMC_2024.pdf 1 3.3 MB Publisher’s postprint open-access - 2.0585794 - ÚOCHB 2025 RIV US eng J - Journal Article
Fleuti, Marianne - Sánchez Quirante, Tania - Poštová Slavětínská, Lenka - Tloušťová, Eva - Tichý, Michal - Gurská, S. - Džubák, P. - Hajdúch, M. - Hocek, Michal
Synthesis and Biological Profiling of Quinolino-Fused 7-Deazapurine Nucleosides.
ACS Omega. Roč. 9, č. 18 (2024), s. 20557-20570. ISSN 2470-1343. E-ISSN 2470-1343
R&D Projects: GA MŠMT LX22NPO5102; GA MŠMT(CZ) LM2023053
Research Infrastructure: CZ-OPENSCREEN IV - 90252
Institutional support: RVO:61388963
Keywords : center-dot-licl * enzymatic incorporation * analogs
Impact factor: 4.1, year: 2022
Method of publishing: Open access
https://doi.org/10.1021/acsomega.4c02031
Permanent Link: https://hdl.handle.net/11104/0353484File Download Size Commentary Version Access 10.1021acsomega.4c02031.pdf 0 2.5 MB Publisher’s postprint open-access - 3.0577107 - ÚOCHB 2024 RIV DE eng J - Journal Article
Yang, Chao - Tichý, Michal - Poštová Slavětínská, Lenka - Vaiedelich, Enzo - Gurská, S. - Džubák, P. - Hajdúch, M. - Hocek, Michal
Synthesis and Biological Profiling of Benzofuro-Fused 7-Deazapurine Nucleosides.
European Journal of Organic Chemistry. Roč. 26, č. 44 (2023), č. článku e202300723. ISSN 1434-193X. E-ISSN 1099-0690
R&D Projects: GA MŠMT LX22NPO5102
Research Infrastructure: CZ-OPENSCREEN IV - 90252; EATRIS-CZ IV - 90253
Institutional support: RVO:61388963
Keywords : cross-coupling * cytotoxicity * glycosylation * nucleosides * 7-deazapurine
OECD category: Organic chemistry
Impact factor: 2.8, year: 2022
Method of publishing: Open access
https://doi.org/10.1002/ejoc.202300723
Permanent Link: https://hdl.handle.net/11104/0346357File Download Size Commentary Version Access 10.1002ejoc.202300723.pdf 1 3.4 MB Publisher’s postprint open-access - 4.0563594 - ÚOCHB 2023 RIV US eng J - Journal Article
Yang, Chao - Poštová Slavětínská, Lenka - Fleuti, Marianne - Klepetářová, Blanka - Tichý, Michal - Gurská, S. - Pavliš, P. - Džubák, P. - Hajdúch, M. - Hocek, Michal
Synthesis of Polycyclic Hetero-Fused 7-Deazapurine Heterocycles and Nucleosides through C-H Dibenzothiophenation and Negishi Coupling.
Journal of the American Chemical Society. Roč. 144, č. 42 (2022), s. 19437-19446. ISSN 0002-7863. E-ISSN 1520-5126
R&D Projects: GA MŠMT LX22NPO5102; GA MŠMT(CZ) LM2018133
Research Infrastructure: CZ-OPENSCREEN III - 90130
Institutional support: RVO:61388963
Keywords : enzymatic incorporation * antiviral activity * analogs
OECD category: Biochemistry and molecular biology
Impact factor: 15, year: 2022
Method of publishing: Open access
https://doi.org/10.1021/jacs.2c07517
Permanent Link: https://hdl.handle.net/11104/0335502File Download Size Commentary Version Access 10.1021jacs.2c07517.pdf 2 2.7 MB Publisher’s postprint open-access - 5.0541879 - ÚOCHB 2022 RIV US eng J - Journal Article
Perlíková, Pavla - Krajczyk, Anna - Doleželová, Eva - Slapničková, Martina - Milisavljevič, Nemanja - Poštová Slavětínská, Lenka - Tloušťová, Eva - Gurská, S. - Džubák, P. - Hajdúch, M. - Zíková, Alena - Hocek, Michal
Synthesis and Antitrypanosomal Activity of 6-Substituted 7-Methyl-7-deazapurine Nucleosides.
ACS Infectious Diseases. Roč. 7, č. 4 (2021), s. 917-926. ISSN 2373-8227
R&D Projects: GA MŠMT(CZ) EF16_019/0000729; GA MŠMT(CZ) EF16_019/0000759; GA ČR(CZ) GA19-08124S; GA ČR(CZ) GA19-07707S; GA MŠMT(CZ) LM2015064
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963 ; RVO:60077344
Keywords : nucleosides * antiparasitic activity * antitrypanosomal * cytotoxicity
OECD category: Organic chemistry; Organic chemistry (BC-A)
Impact factor: 5.578, year: 2021
Method of publishing: Limited access
https://doi.org/10.1021/acsinfecdis.1c00062
Permanent Link: http://hdl.handle.net/11104/0319376 - 6.0534197 - ÚOCHB 2021 RIV US eng J - Journal Article
Veselovská, Lucia - Pohl, Radek - Tloušťová, Eva - Gurská, S. - Džubák, P. - Hajdúch, M. - Hocek, Michal
Pyrido-Fused Deazapurine Bases: Synthesis and Glycosylation of 4-Substituted 9H-Pyrido[2′,3′:4,5]- and Pyrido[4′,3′:4,5]pyrrolo[2,3-d]pyrimidines.
ACS Omega. Roč. 5, č. 40 (2020), s. 26278-26286. ISSN 2470-1343. E-ISSN 2470-1343
R&D Projects: GA ČR(CZ) GA19-08124S; GA MŠMT(CZ) LM2015064
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963
Keywords : Thymidylate synthase inhibitors * receptor tyrosine kinase * biological activity
OECD category: Organic chemistry
Impact factor: 3.512, year: 2020
Method of publishing: Open access
https://doi.org/10.1021/acsomega.0c04302
Permanent Link: http://hdl.handle.net/11104/0312441 - 7.0532766 - ÚOCHB 2021 RIV DE eng J - Journal Article
Veselovská, Lucia - Kudlová, N. - Gurská, S. - Lišková, B. - Medvedíková, M. - Hodek, Ondřej - Tloušťová, Eva - Milisavljevič, Nemanja - Tichý, Michal - Perlíková, Pavla - Mertlíková-Kaiserová, Helena - Trylčová, Jana - Pohl, Radek - Klepetářová, Blanka - Džubák, P. - Hajdúch, M. - Hocek, Michal
Synthesis and Cytotoxic and Antiviral Activity Profiling of All-Four Isomeric Series of Pyrido-Fused 7-Deazapurine Ribonucleosides.
Chemistry - A European Journal. Roč. 26, č. 57 (2020), s. 13002-13015. ISSN 0947-6539. E-ISSN 1521-3765
R&D Projects: GA ČR(CZ) GA19-08124S; GA MZd(CZ) NV15-31984A; GA MŠMT(CZ) LM2015064
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963
Keywords : antitumor agents * antiviral agents * drug discovery * phosphorylation * ribonucleosides
OECD category: Organic chemistry
Impact factor: 5.236, year: 2020
Method of publishing: Limited access
https://doi.org/10.1002/chem.202001124
Permanent Link: http://hdl.handle.net/11104/0311179 - 8.0532387 - ÚOCHB 2021 RIV US eng J - Journal Article
Fleuti, Marianne - Bártová, Kateřina - Poštová Slavětínská, Lenka - Tloušťová, Eva - Tichý, Michal - Gurská, S. - Pavliš, P. - Džubák, P. - Hajdúch, M. - Hocek, Michal
Synthesis and Biological Profiling of Pyrazolo-Fused 7-Deazapurine Nucleosides.
Journal of Organic Chemistry. Roč. 85, č. 16 (2020), s. 10539-10551. ISSN 0022-3263. E-ISSN 1520-6904
R&D Projects: GA ČR(CZ) GA19-08124S; GA MZd(CZ) NV15-31984A; GA MŠMT(CZ) LM2015064
Grant - others:AV ČR(CZ) AP1501
Program: Akademická prémie - Praemium Academiae
Institutional support: RVO:61388963
Keywords : tyrosine kinase * inhibitors * adenosine
OECD category: Organic chemistry
Impact factor: 4.354, year: 2020
Method of publishing: Limited access
https://doi.org/10.1021/acs.joc.0c00928
Permanent Link: http://hdl.handle.net/11104/0310889 - 9.0531532 - ÚOCHB 2021 RIV US eng J - Journal Article
Yang, Chao - Pohl, Radek - Tichý, Michal - Gurská, S. - Pavliš, P. - Džubák, P. - Hajdúch, M. - Hocek, Michal
Synthesis, Photophysical Properties, and Biological Profiling of Benzothieno-Fused 7-Deazapurine Ribonucleosides.
Journal of Organic Chemistry. Roč. 85, č. 12 (2020), s. 8085-8101. ISSN 0022-3263. E-ISSN 1520-6904
R&D Projects: GA ČR(CZ) GA19-08124S; GA MZd(CZ) NV15-31984A; GA MŠMT(CZ) LM2015064
Institutional support: RVO:61388963
Keywords : nucleoside * inhibitors * antitumor
OECD category: Organic chemistry
Impact factor: 4.354, year: 2020
Method of publishing: Limited access
https://doi.org/10.1021/acs.joc.0c00927
Permanent Link: http://hdl.handle.net/11104/0310168 - 10.0531266 - ÚMG 2021 RIV FR eng J - Journal Article
Dvořanová, J. - Kugler, Michael - Holub, J. - Šícha, V. - Das, V. - Nekvinda, J. - El Anwar, S. - Havránek, M. - Pospíšilová, K. - Fábry, Milan - Král, Vlastimil - Medvědiková, M. - Matějková, S. - Lišková, B. - Gurská, S. - Dzubak, P. - Brynda, Jiří - Hajduch, M. - Gruner, B. - Řezáčová, P.
Sulfonamido carboranes as highly selective inhibitors of cancer-specific carbonic anhydrase IX.
European Journal of Medicinal Chemistry. Roč. 200, August (2020), č. článku 112460. ISSN 0223-5234. E-ISSN 1768-3254
R&D Projects: GA ČR(CZ) GA15-05677S
Institutional support: RVO:68378050
Keywords : Anti-tumor agents * Carbonic anhydrase IX * Carboranes * Dicarbollide * Enzyme inhibitors * Drug penetration * Multicellular spheroids
OECD category: Medicinal chemistry
Impact factor: 6.514, year: 2020
Method of publishing: Limited access
https://www.sciencedirect.com/science/article/abs/pii/S0223523420304311?via%3Dihub
Permanent Link: http://hdl.handle.net/11104/0309958