Search results
- 1.0576080 - ÚOCHB 2024 RIV NL eng J - Journal Article
Zgarbová, Michala - Otava, Tomáš - Šilhán, Jan - Nencka, Radim - Weber, Jan - Bouřa, Evžen
Inhibitors of mpox VP39 2′-O methyltransferase efficiently inhibit the monkeypox virus.
Antiviral Research. Roč. 218, October (2023), č. článku 105714. ISSN 0166-3542. E-ISSN 1872-9096
R&D Projects: GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Keywords : structural basis
OECD category: Virology
Impact factor: 7.6, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.antiviral.2023.105714
Permanent Link: https://hdl.handle.net/11104/0345703File Download Size Commentary Version Access 10.1016j.antiviral.2023.105714.pdf 0 1.7 MB Publisher’s postprint open-access - 2.0574116 - ÚEM 2024 RIV US eng J - Journal Article
Kortus, Štěpán - Řeháková, Kristýna - Klíma, Martin - Kolcheva, Marharyta - Ladislav, Marek - Langore, Emily - Baráčková, Petra - Netolický, Jakub - Misiachna, Anna - Hemelíková, Katarína - Humpolíčková, Jana - Chalupská, Dominika - Šilhán, Jan - Kaniaková, Martina - Hrčka Krausová, Barbora - Bouřa, Evžen - Zápotocký, Martin - Horák, Martin
Subunit-Dependent Surface Mobility and Localization of NMDA Receptors in Hippocampal Neurons Measured Using Nanobody Probes.
Journal of Neuroscience. Roč. 43, č. 26 (2023), s. 4755-4774. ISSN 0270-6474. E-ISSN 1529-2401
R&D Projects: GA ČR(CZ) GA20-12420S; GA MŠMT(CZ) LX22NPO5107
Research Infrastructure: Czech-BioImaging III - 90250; Czech-BioImaging II - 90129
Institutional support: RVO:68378041 ; RVO:61388963 ; RVO:67985823
Keywords : GluN subunit * excitatory synapse * glutamate receptor * lateral diffusion * live microscopy * mammalian neuron
OECD category: Neurosciences (including psychophysiology; Biochemistry and molecular biology (UOCHB-X); Biochemistry and molecular biology (FGU-C)
Impact factor: 5.3, year: 2022
Method of publishing: Open access
https://www.jneurosci.org/content/43/26/4755
Permanent Link: https://hdl.handle.net/11104/0344475File Download Size Commentary Version Access Kortus 2023.pdf 4 4.6 MB Publisher’s postprint open-access - 3.0574061 - ÚOCHB 2024 RIV NL eng J - Journal Article
Škvára, Petr - Chalupská, Dominika - Klíma, Martin - Kozic, Ján - Šilhán, Jan - Bouřa, Evžen
Structural basis for RNA-cap recognition and methylation by the mpox methyltransferase VP39.
Antiviral Research. Roč. 216, August (2023), č. článku 105663. ISSN 0166-3542. E-ISSN 1872-9096
R&D Projects: GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Keywords : messenger-RNA * virus methyltransferase
OECD category: Virology
Impact factor: 7.6, year: 2022
Method of publishing: Open access
https://doi.org/10.1016/j.antiviral.2023.105663
Permanent Link: https://hdl.handle.net/11104/0344428File Download Size Commentary Version Access 10.1016j.antiviral.2023.105663.pdf 1 3 MB Publisher’s postprint open-access
Research data: PDB - 4.0571446 - ÚOCHB 2024 RIV US eng J - Journal Article
Šilhán, Jan - Klíma, Martin - Otava, Tomáš - Škvára, Petr - Chalupská, Dominika - Chalupský, Karel - Kozic, Ján - Nencka, Radim - Bouřa, Evžen
Discovery and structural characterization of monkeypox virus methyltransferase VP39 inhibitors reveal similarities to SARS-CoV-2 nsp14 methyltransferase.
Nature Communications. Roč. 14, April (2023), č. článku 2259. E-ISSN 2041-1723
R&D Projects: GA MŠMT(CZ) LX22NPO5103
Institutional support: RVO:61388963
Keywords : messenger RNA * recognition * binding
OECD category: Virology
Impact factor: 16.6, year: 2022
Method of publishing: Open access
https://doi.org/10.1038/s41467-023-38019-1
Permanent Link: https://hdl.handle.net/11104/0342665File Download Size Commentary Version Access 10.1038s41467-023-38019-1.pdf 0 1.9 MB Publisher’s postprint open-access - 5.0561949 - ÚOCHB 2023 RIV GB eng J - Journal Article
Hušková, Andrea - Dinesh, Dhurvas Chandrasekaran - Srb, Pavel - Bouřa, Evžen - Veverka, Václav - Šilhán, Jan
Model of abasic site DNA cross-link repair, from the architecture of NEIL3 DNA binding domains to the X-structure model.
Nucleic Acids Research. Roč. 50, č. 18 (2022), s. 10436-10448. ISSN 0305-1048. E-ISSN 1362-4962
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : covalent structure * crystal-structure * fanconis anemia
OECD category: Biochemistry and molecular biology
Impact factor: 14.9, year: 2022
Method of publishing: Open access
https://doi.org/10.1093/nar/gkac793
Permanent Link: https://hdl.handle.net/11104/0334376 - 6.0556771 - ÚOCHB 2023 RIV NL eng J - Journal Article
Hušková, Andrea - Landová, Barbora - Bouřa, Evžen - Šilhán, Jan
The rate of formation and stability of abasic site interstrand crosslinks in the DNA duplex.
Dna Repair. Roč. 113, May (2022), č. článku 103300. ISSN 1568-7864. E-ISSN 1568-7856
R&D Projects: GA ČR(CZ) GJ17-21649Y
Institutional support: RVO:61388963
Keywords : DNA damage * interstrand crosslink * abasic site * non-enzyme kinetics * DNA repair
OECD category: Biochemistry and molecular biology
Impact factor: 3.8, year: 2022
Method of publishing: Limited access
https://doi.org/10.1016/j.dnarep.2022.103300
Permanent Link: http://hdl.handle.net/11104/0330959 - 7.0555984 - ÚOCHB 2023 RIV GB eng J - Journal Article
Nencka, Radim - Šilhán, Jan - Klíma, Martin - Otava, Tomáš - Kocek, Hugo - Krafčíková, Petra - Bouřa, Evžen
Coronaviral RNA-methyltransferases: function, structure and inhibition.
Nucleic Acids Research. Roč. 50, č. 2 (2022), s. 635-650. ISSN 0305-1048. E-ISSN 1362-4962
R&D Projects: GA ČR(CZ) GA21-25280S; GA MZd(CZ) NU20-05-00472; GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : structure guided design * SARS coronavirus * SARS-CoV-2 replication
OECD category: Biochemistry and molecular biology
Impact factor: 14.9, year: 2022
Method of publishing: Open access
https://doi.org/10.1093/nar/gkab1279
Permanent Link: http://hdl.handle.net/11104/0330958 - 8.0544176 - ÚOCHB 2022 RIV US eng J - Journal Article
Dostalík, Pavel - Krafčíková, Petra - Šilhán, Jan - Kozic, Ján - Chalupská, Dominika - Chalupský, Karel - Bouřa, Evžen
Structural Analysis of the OC43 Coronavirus 2′-O-RNA Methyltransferase.
Journal of Virology. Roč. 95, č. 15 (2021), č. článku e00463-21. ISSN 0022-538X. E-ISSN 1098-5514
R&D Projects: GA ČR(CZ) GA21-25280S
Institutional support: RVO:61388963
Keywords : OC43 * coronavirus * crystal structure * methyltransferase
OECD category: Biochemistry and molecular biology
Impact factor: 6.549, year: 2021
Method of publishing: Open access with time embargo
https://doi.org/10.1128/JVI.00463-21
Permanent Link: http://hdl.handle.net/11104/0321236 - 9.0544070 - ÚOCHB 2022 RIV CH eng J - Journal Article
Cihlová, Bára - Hušková, Andrea - Böserle, Jiří - Nencka, Radim - Bouřa, Evžen - Šilhán, Jan
High-Throughput Fluorescent Assay for Inhibitor Screening of Proteases from RNA Viruses.
Molecules. Roč. 26, č. 13 (2021), č. článku 3792. E-ISSN 1420-3049
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Institutional support: RVO:61388963
Keywords : high-throughput screening * virus * drug * discovery * papain-like * protease * SARS-CoV-2 * flavivirus * TBEV
OECD category: Biochemistry and molecular biology
Impact factor: 4.927, year: 2021
Method of publishing: Open access
https://doi.org/10.3390/molecules26133792
Permanent Link: http://hdl.handle.net/11104/0321123 - 10.0536797 - ÚOCHB 2021 RIV US eng J - Journal Article
Dinesh, Dhurvas Chandrasekaran - Chalupská, Dominika - Šilhán, Jan - Koutná, Eliška - Nencka, Radim - Veverka, Václav - Bouřa, Evžen
Structural basis of RNA recognition by the SARS-CoV-2 nucleocapsid phosphoprotein.
PLoS Pathogens. Roč. 16, č. 12 (2020), č. článku e1009100. ISSN 1553-7366. E-ISSN 1553-7374
R&D Projects: GA MŠMT(CZ) EF16_019/0000729
Grant - others:AV ČR(CZ) L200551951
Institutional support: RVO:61388963
Keywords : N-terminal domain * binding domain * crystal structure
OECD category: Biochemistry and molecular biology
Impact factor: 6.823, year: 2020
Method of publishing: Open access
https://doi.org/10.1371/journal.ppat.1009100
Permanent Link: http://hdl.handle.net/11104/0316257